What is Fludeoxyglucose and how does it work?
cancer, coronary artery disease, or epileptic seizures.
Fludeoxyglucose F 18 Injection,USP is indicated in PET (positron emission tomography) for:
- Identification of regions of abnormal glucose metabolism associated with foci of epileptic seizures.
- Assessment of abnormal glucose metabolism to assist in the evaluation of malignancy in patients with known or suspected abnormalities found by other testing modalities, or in patients with an existing diagnosis of cancer.
- Assessment of patients with coronary artery disease and left ventricular dysfunction, when used together with myocardial perfusion imaging, for the identification of left ventricular myocardium with residual glucose metabolism and reversible loss of systolic function.
Fludeoxyglucose F 18 Injection, USP is not indicated for distinguishing epileptogenic foci from brain tumors or other brain lesions which may cause seizures.
What is the dosage for Fludeoxyglucose?
- F 18 (FDG) uptake may be changed by fasting or by blood sugar changes associated with diabetic mellitus.
- Blood glucose levels should be stabilized in non-diabetic patients by fasting before F 18 (FDG) injection.
- Diabetic patients may need stabilization of blood glucose on the day preceding and on the day of the F 18 (FDG) scan.
- The recommended dose of F 18 (FDG) for an adult (70 kg) is within the range 185-370 MBq (5-10 mCi), intravenous injection.
- In children doses as low as 2.6 mCi have been given.
- Optimal dose reductions for children have not been confirmed.
- The optimum rate of administration and upper safe dose for F 18 (FDG) have not been established.
- The time interval between doses of F 18 (FDG) should be long enough to allow substantial decay (physical and biological) of previous administrations.
- It is recommended that PET imaging be initiated within 40 minutes of F 18 (FDG) injection.
- The final dose for the patient should be calculated using proper decay factors from the time of the EOS, and measured by a suitable radioactivity calibration system before administration.
- F 18 (FDG), like other parenteral drug products, should be inspected visually for particulate matter and discoloration before administration, whenever solution and container permit.
- Preparations containing particulate matter or discoloration should not be administered. They should be disposed of in a safe manner, in compliance with applicable regulations.
- F 18 (FDG) should be stored upright in a lead shielded environment at controlled room temperature.
- Aseptic techniques and effective shielding should be employed in withdrawing doses for administration to patients.
- Waterproof gloves and effective shielding should be worn when handling the product.
Is Fludeoxyglucose safe to take when pregnant or breastfeeding?
- It is not known whether F 18 (FDG) can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. Therefore, F 18 (FDG) should not be administered to a pregnant woman unless the potential benefit justifies the potential risk to the fetus.
- It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when F 18 (FDG) is administered to a nursing woman.
Fludeoxyglucose F 18 Injection (fdg) is a positron emitting radiopharmaceutical used for diagnostic purposes in conjunction with Positron Emission Tomography (PET). It is also used to assist assessment of cancer, coronary artery disease, or epileptic seizures.
Multimedia: Slideshows, Images & Quizzes
Understanding Cancer: Metastasis, Stages of Cancer, and More
Learn the basics about cancer including types, causes, how it spreads, symptoms and signs, stages and treatment options. Read...
Skin Cancer Symptoms, Types, Images
Discover the causes, types, and treatments of skin cancer. Learn how to prevent skin cancer and how to check for melanoma, basal...
Signs of Cancer in Women: Symptoms You Can't Ignore
Colon and stomach cancer symptoms can surprise women but can be treated if detected early. Learn about breast cancer signs and...
Cancer: Guide to Leukemia
Learn about the common types and stages of leukemia, who gets it, symptoms, tests, treatments, and more. People with blood cancer...
Cancer-Fighting Foods: Resveratrol, Green Tea, and More
Experts have praised certain foods for their ability to reduce cancer risks. Learn which foods and eating strategies may help...
Top 10 Cancers Quiz
Take this quiz to learn the causes of cancer. Get the facts about the causes, symptoms, and treatments for the world's most...
Epilepsy & Seizures Quiz: What Causes Seizures?
Do you know the difference between seizures and epilepsy? What are the types of seizures? Take the Epilepsy & Seizures Quiz to...
Cancer: Visual Guide to Thyroid Cancer
Find out the symptoms of thyroid cancer, and learn how to treat it after you get a diagnosis.
Cancer: Does This Cause Cancer?
Everything gives you cancer, right? Not really. WebMD's slide show tells you about the research into cancer and cell phones,...
Cancer: How to Lower and Cut Your Risk of Cancer
About a third of all cases of cancer can be prevented. Find out how to lower your chances of getting it.
Cancer: Symptoms of Common Cancers in Men
Can men get breast cancer? Cancer symptoms men need to watch out for include skin changes, difficulty swallowing, rapid weight...
Cancer: Cancer 'Remedies' That Don't Work
You may have read about an all-natural cure for cancer. While many therapies are helpful, some aren't worth your time or money....
Related Disease Conditions
Cancer is a disease caused by an abnormal growth of cells, also called malignancy. It is a group of 100 different diseases, and is not contagious. Cancer can be treated through chemotherapy, a treatment of drugs that destroy cancer cells.
Heart disease (coronary artery disease) occurs when plaque builds up in the coronary arteries, the vessels that supply blood to the heart. Heart disease can lead to heart attack. Risk factors for heart disease include: Smoking High blood pressure High cholesterol Diabetes Family history Obesity Angina, shortness of breath, and sweating are just a few symptoms that may indicate a heart attack. Treatment of heart disease involves control of heart disease risk factors through lifestyle changes, medications, and/or stenting or bypass surgery. Heart disease can be prevented by controlling heart disease risk factors.
Cancer Risk Factors and Causes
Though it's difficult to say why some people develop cancer while others don't, research shows that certain risk factors increase a person's odds of developing cancer. These risk factors include growing older, family history of cancer, diet, alcohol and tobacco use, and exposure to sunlight, ionizing radiation, certain chemicals, and some viruses and bacteria.
Migraines and Seizures
Migraines are a type of headache and seizures are the main symptom of epilepsy. Migraine headaches and seizures are two different neurological problems that have similar signs, symptoms, and auras, for example, sensitivity to light (photophobia) and sound, irritability, nausea, and vomiting. Symptoms unique to migraine and migraine auras are water retention, problems sleeping, appetite changes, and talkativeness. Symptoms unique to seizure and seizures auras are depression, a feeling of heaviness, a feeling that a seizure is approaching, and depression. Many of the symptoms of migraine and seizures are the same, however, seizures do not cause migraines; however, people who have seizures are twice as likely to have migraines and vice-versa. People who have migraines are twice as likely to have seizures, and people with seizures are twice as likely to have migraines; however, one condition does not cause the other.
Seizures: Symptoms and Types
Seizures occur when there is an abnormal burst of electrical activity in the brain and are divided into two categories: generalized and partial. Learn about the symptoms of different types of seizures, and check out the center below for more medical references on seizures, including multimedia (slideshows, images, and quizzes), related diseases, treatment, diagnosis, medications, and prevention or wellness.
Is Cancer Contagious?
Cancer is an abnormal growth of cells. A variety of parasites and viruses have been linked to various cancers. Cancer may metastasize, spreading from its original location to other organs. If you have cancer, you should seek medical care immediately if you experience high fever, shortness of breath, intense headaches, vomiting blood or passing blood rectally, chest pain or moderate to severe weakness, passing out (fainting), mental status changes, or seizures.
Seizure vs. Seizure Disorders: What's the Difference?
Seizures and seizure disorders are not the same medical problems. A seizure happens when the electrical activity in the brain is uncontrolled. There are about 40 different types of seizure disorders, in which epilepsy is one. Symptoms depend on the type of disorder, but can include loss of consciousness, uncontrolled twitching or shaking of one side, or the entire body.
Epilepsy and Seizures: How to Treat?
A seizure is a sudden, uncontrolled electrical disturbance in the brain. Epilepsy is a neurological disorder where brain activities are abnormal, causing more than one or recurrent episodes of seizures. Most cases of seizures can be managed conservatively with medication and supportive treatments.
Cancer pain is a common experience that may result from the disease, treatment, or diagnostic procedure. Check out the center below for more medical references on cancer, including multimedia (slideshows, images, and quizzes), related disease conditions, treatment and diagnosis, medications, and prevention or wellness.
Treatment & Diagnosis
- Seizure (Epilepsy)
- Cancer: Confronting Cancer with Humor
- Cancer: The Importance of Joining a Cancer Support Group with Selma Schimmel
- Cancer Survival and Attitude with Hamilton Jordan
- Cancer and Green Tea
- Cancer Pain Management with Ann Reiner
- Cancer Patients Need Proper Diet and Exercise
- Epilepsy: Silencing the Seizures
- Cancer: Journaling to Save Your Life
- Cancer: Emotional Aftershocks: When Cancer Comes Back 10/30/02
- Cancer: Living Well Despite with Win Boerckel
- Cancer Treatment: Writing to Heal with Margie Davis
- Cancers: Children's Cancers
- Cancer: Childhood Cancer Survivors
- Cancer Research: Going the Distance
- Epilepsy and Seizures FAQs
- Cancer FAQs
- Cancer,Stroke & Heart Attack Risks- ReducedThrough Walking
- Cancer Care in the Elderly
- Seizure Symptoms: How to Assist the Victim
- Cancer Survivor?
- Seizures: When the Computer Goes Haywire
- Does Lupus Cause Seizures?
- 10 Cancer Symptoms That Men Ignore
- Cancer Prevention: The Anticancer Diet
Medications & Supplements
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.