Medical Definition of Fissure

Reviewed on 3/29/2021

Fissure: A cleft or groove. A fissure can be normal or abnormal.

A fissure in the cerebral cortex is a normal feature. It is a deep fold that involves the entire thickness of the brain wall.

A fissure in the anus is abnormal. It is a painful crack in the edge of the anus and is very painful. Also called an anal fissure or fissure in ano.

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