- What is feverfew (tanacetum parthenium)-oral, and how does it work (mechanism of action)?
- What brand names are available for feverfew (tanacetum parthenium)-oral?
- Is feverfew (tanacetum parthenium)-oral available as a generic drug?
- Do I need a prescription for feverfew (tanacetum parthenium)-oral?
- What are the side effects of feverfew (tanacetum parthenium)-oral?
- What is the dosage for feverfew (tanacetum parthenium)-oral?
- Which drugs or supplements interact with feverfew (tanacetum parthenium)-oral?
- Is feverfew (tanacetum parthenium)-oral safe to take if I'm pregnant or breastfeeding?
- What else should I know about feverfew (tanacetum parthenium)-oral?
What is feverfew (tanacetum parthenium)-oral, and how does it work (mechanism of action)?
Tanacetum parthenium is an herb. The leaves are used as a natural herbal supplement. Tanacetum parthenium contains parthenolide, which works on serotonin receptors in the brain, giving relief from migraine headaches. Tanacetum parthenium is also believed to have anti-inflammatory, pain relieving, and anti-histamine effects. Check with your health-care professional before using herbs or herbal supplements.
What brand names are available for feverfew (tanacetum parthenium)-oral?
Feverfew, Bachelor's Buttons, Featherfew
What are the side effects of feverfew (tanacetum parthenium)-oral?
Common side effects of Tanacetum parthenium are oral ulcers and tongue soreness if dried leaves are chewed. It can cause increased heart rates, dizziness, anxiety, sleeplessness, abdominal pain, bloating, nausea, and diarrhea.
What is the dosage for feverfew (tanacetum parthenium)-oral?
Migraine headache prevention: Take 50 – 100 mg dried leaf extract by mouth once daily; for other preparations, see manufacturer's directions.
Safe and effective use of Tanacetum parthenium is not established for individuals under the age of 18.
Which drugs or supplements interact with feverfew (tanacetum parthenium)-oral?
: Tanacetum parthenium should be used with caution with warfarin (Coumadin), clopidogrel (Plavix), and aspirin because Tanacetum parthenium can decrease clotting, increasing bleeding risk from these medications.
Tanacetum parthenium may reduce break down or conversion of drugs in the liver. Examples include omeprazole (Prilosec), lansoprazole (Prevacid), amiodarone (Cordarone), lovastatin (Mevacor), ketoconazole (Nizoral), and itraconazole (Sporanox). Check with your doctor before using this herbal product.

QUESTION
Who suffers more frequently from migraine headaches? See AnswerIs feverfew (tanacetum parthenium)-oral safe to take if I'm pregnant or breastfeeding?
It is not known whether Tanacetum parthenium enters breast milk; It should be avoided by nursing mothers to prevent harm to the newborn.
What else should I know about feverfew (tanacetum parthenium)-oral?
What preparations of feverfew (tanacetum parthenium)-oral are available?
Tanacetum parthenium is available as oral capsules, dried leaf extract, and as a liquid extract. Concentration of Tanacetum parthenium may vary from product-to-product due to multiple manufacturers producing various products.
How should I keep feverfew (tanacetum parthenium)-oral stored?
Due to multiple manufacturers making different forms of Tanacetum parthenium, storage requirements may vary based on individual manufacturer practices.
Summary
Feverfew, Bachelor's Buttons, Featherfew (Tanacetum parthenium, Chrysanthemum parthenium) is an herbal supplement used to prevent and treat migraine headahces. Consult your health-care professional before you take any herbal supplments. Side effects, drug interactions, dosage, storage, and pregnancy safety should be reviewed prior to taking this product.
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Treatment & Diagnosis
Medications & Supplements

Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
REFERENCES:
MedlinePlus Supplements. Feverfew.
NIH. Feverfew.