- High Blood Pressure Slideshow Pictures
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- What is felodipine, and how does it work?
- What brand names are available for felodipine?
- Is this drug available as a generic ?
- Do I need a prescription for it?
- Why doctors prescribe (uses) felodipine?
- What are the side effects of felodipine?
- How should I take this drug (dosage)?
- Which drugs, supplements, or foods interact with felodipine?
- Is it safe to take if I'm pregnant or breastfeeding?
- What else should I know about this drug?
What is felodipine, and how does it work?
Felodipine is an oral calcium channel blocker (CCB) of the dihydropyridine (DHP) class. Other calcium channel blockers in the DHP class include:
- nifedipine (Procardia, Adalat)
- amlodipine (Norvasc)
- nisoldipine (Sular)
- nicardipine (Cardene)
- isradipine (Dynacirc)
Calcium is necessary for muscle cells to contract. Felodipine prevents calcium from being released within the muscle cells of the small arteries and thereby causes the muscles to relax and the arteries to dilate or expand. Dilation of arteries reduces blood pressure. It has little or no effect on the muscles of veins or the heart.
What brand names are available for felodipine?
Plendil is the brand name available for this drug in the US.
Quick GuideHow to Lower Blood Pressure: Exercise Tips
Do I need a prescription for it?
Yes, you need a prescription from your doctor or health care professional.
Why doctors prescribe (uses) felodipine?
What are the side effects of felodipine?
The most common side effects reported by patients include:
- Peripheral edema (swollen ankles and feet)
- Increased heart rate
- Low blood pressure
Other important side effects include:
How should I take this drug (dosage)?
- The recommended dose of felodipine is 2.5-10 mg once daily.
- It should be taken without food or with no more than a light meal since food may reduce its absorption.
- Since felodipine comes as a sustained-release tablet, it should be swallowed whole. It should not be chewed or crushed.
Which drugs, supplements, or foods interact with felodipine?
- Cimetidine (Tagamet), ketoconazole (Nizoral, Extina, Xolegel, Kuric), itraconazole (Sporanox), and erythromycin can block the breakdown of felodipine, resulting in higher blood concentrations of felodipine and drops in blood pressure.
- Carbamazepine (Tegretol), phenobarbital, or phenytoin (Dilantin) can lower felodipine blood concentrations. Therefore, higher doses of felodipine may be necessary in patients receiving these medications.
- Taking felodipine with grapefruit juice increases its absorption and may lead to sudden drops in blood pressure.
- Felodipine may increase blood concentrations of tacrolimus (Prograf). Tacrolimus blood concentrations should be monitored and the dose should be modified as necessary.
Is it safe to take if I'm pregnant or breastfeeding?
- There aren't any adequate studies on the effects of felodipine in ppregnant women. Animal studies have shown adverse effects. Therefore, your doctor or health care professional must weigh the potential risks to the fetus against the potential benefits to the you.
- We don't know if felodipine is excreted in breast milk.
What else should I know about this drug?
- It's available as tablets (extended Release) in 2.5, 5, and 10 mg
- You should keep the tablets stored below 86 F (30 C) and protect them from light and moisture.
- Felodipine was approved by the FDA in 1991.
Felodipine (Plendil) is a drug prescribed for the treatment of high blood pressure to prevent heart attack and stroke. Doctors also prescribe it to treat patients for angina, however, it is not an FDA approved drug for this condition.
Common side effects include:
Multimedia: Slideshows, Images & Quizzes
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- Sugar FAQs
- High Blood Pressure FAQs
- Heart Disease FAQs
- Salt FAQs
- How To Reduce Your Medication Costs
- Pharmacy Visit, How To Get The Most Out of Your Visit
- Indications for Drugs: Approved vs. Non-approved
- Drugs: Buying Prescription Drugs Online Safely
- Drugs: The Most Common Medication Errors
- Medication Disposal
- Dangers of Mixing Medications
- Grapefruit Juice and Drug Interactions
- Generic Drugs, Are They as Good as Brand-Names?
Medications & Supplements
- High Blood Pressure Drugs (Hypertension)
- Drugs: Questions to Ask Your Doctor or Pharmacist about Your Drugs
- Drug Interactions
- Calcium Channel Blockers (CCBs)
- amlodipine, Norvasc
- nifedipine, Adalat (discontinued brand), Procardia, Afeditab, Nifediac
- nicardipine, Cardene, Cardene SR
- bepridil (Vascor, Bepadin - Discontinued)
Prevention & Wellness
Heart Health Resources
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Top felodipine Related Articles
Angina SymptomsAngina is chest pain due to inadequate blood supply to the heart. Angina symptoms may include chest tightness, burning, squeezing, and aching. Coronary artery disease is the main cause of angina but there are other causes. Angina is diagnosed by taking the patient's medical history and performing tests such as an electrocardiogram (EKG), blood test, stress test, echocardiogram, cardiac CT scan, and heart catheterization. Treatment of angina usually includes lifestyle modification, medication, and sometimes, surgery. The risk of angina can be reduced by following a heart healthy lifestyle.
Congestive Heart Failure (CHF) OverviewCongestive heart failure (CHF) refers to a condition in which the heart loses the ability to function properly. Heart disease, high blood pressure, diabetes, myocarditis, and cardiomyopathies are just a few potential causes of congestive heart failure. Signs and symptoms of congestive heart failure may include fatigue, breathlessness, palpitations, angina, and edema. Physical examination, patient history, blood tests, and imaging tests are used to diagnose congestive heart failure. Treatment of heart failure consists of lifestyle modification and taking medications to decrease fluid in the body and ease the strain on the heart. The prognosis of a patient with congestive heart failure depends on the stage of the heart failure and the overall condition of the individual.
A heart attack happens when a blood clot completely obstructs a coronary artery supplying blood to the heart muscle. A heart attack can cause chest pain, heart failure, and electrical instability of the heart.
Heart Attack Symptoms and Early Warning SignsRecognizing heart attack symptoms and signs can help save your life or that of someone you love. Some heart attack symptoms, including left arm pain and chest pain, are well known but other, more nonspecific symptoms may be associated with a heart attack. Nausea, vomiting, malaise, indigestion, sweating, shortness of breath, and fatigue may signal a heart attack. Heart attack symptoms and signs in women may differ from those in men.
Heart Disease (Coronary Artery Disease)
Heart disease (coronary artery disease) occurs when plaque builds up in the coronary arteries, the vessels that supply blood to the heart. Heart disease can lead to heart attack. Risk factors for heart disease include:
- High blood pressure
- High cholesterol
- Family history
Angina, shortness of breath, and sweating are just a few symptoms that may indicate a heart attack. Treatment of heart disease involves control of heart disease risk factors through lifestyle changes, medications, and/or stenting or bypass surgery. Heart disease can be prevented by controlling heart disease risk factors.
CAD SlideshowWhat is heart disease (coronary artery disease)? Learn about the causes of heart disease. Symptoms of heart disease include chest pain and shortness of breath. Explore heart disease diagnosis, treatment, and prevention.
Heart Disease SlideshowLearn about heart disease and heart attack symptoms and signs of a heart attack in men and women. Read about heart disease diagnostic tests, treatments, and prevention strategies.
Heart Disease QuizTake our Heart Disease Quiz to get answers and facts about high cholesterol, atherosclerosis prevention, and the causes, symptoms, treatments, testing, and procedures for medically broken hearts.
Illustrations of the HeartThe muscle that pumps blood received from veins into arteries throughout the body. See a picture of the Heart and learn more about the health topic.
Heart: How the Heart WorksThe heart is a very important organ in the body. It is responsible for continuously pumping oxygen and nutrient-rich blood throughout your body to sustain life. It is a fist-sized muscle that beats (expands and contracts) 100,000 times per day, pumping a total of five or six quarts of blood each minute, or about 2,000 gallons per day.
High Blood Pressure Hypertension
High blood pressure (hypertension) is a disease in which pressure within the arteries of the body is elevated. About 75 million people in the US have hypertension (1 in 3 adults), and only half of them are able to manage it. Many people do not know that they have high blood pressure because it often has no has no warning signs or symptoms.
Systolic and diastolic are the two readings in which blood pressure is measured. The American College of Cardiology released new guidelines for high blood pressure in 2017. The guidelines now state that blood normal blood pressure is 120/80 mmHg. If either one of those numbers is higher, you have high blood pressure.
The American Academy of Cardiology defines high blood pressure slightly differently. The AAC considers 130/80 mm Hg. or greater (either number) stage 1 hypertension. Stage 2 hypertension is considered 140/90 mm Hg. or greater.
If you have high blood pressure you are at risk of developing life threatening diseases like stroke and heart attack.
REFERENCE: CDC. High Blood Pressure. Updated: Nov 13, 2017.
High Blood PressureWhat causes high blood pressure (hypertension)? Know the warning signs and symptoms of high blood pressure. Read about high blood pressure medications, diet, and long term treatments.
Take the HBP QuizTake this quiz and test your IQ of high blood pressure (hypertension), the cardiovascular disease that causes most strokes and heart attacks. How are dizziness, snoring, and gout related to HBP? Find the answer and learn how medical treatments and lifestyle adjustments fight this common problem.
High Blood Pressure TreatmentHigh blood pressure (hypertension) means high pressure (tension) in the arteries. Treatment for high blood pressure include lifestyle modifications (alcohol, smoking, coffee, salt, diet, exercise), drugs and medications such as ACE inhibitors, angiotensin receptor blockers, beta blockers, diuretics, calcium channel blockers (CCBs), alpha blockers, clonidine, minoxidil, and Exforge.
Lower Your BP ExercisesTrying to lower high blood pressure (hypertension)? Discover exercises good for lowering blood pressure, along with other lifestyle changes and medications to prevent high blood pressure.
Omega-3 Fatty AcidsOmega-3 fatty acids are essential fats that help decrease one's cholesterol and triglyceride levels as well as reduce the risk of coronary artery disease. Omega-3s are found in:
- walnuts, and
- canola oil.
ParathyroidectomyParathyroidectomy is the removal of one or more of the parathyroid glands to treat hyperparathyroidism. Risks of parathyroidectomy include:
- paralysis of the vocal cords,
- difficulty swallowing thin liquids,
- difficulty breathing,
- and drug reactions.
- damage to the recurrent laryngeal nerve,
- bleeding or hematoma,
- problems maintaining calcium levels in the blood,
- need for further and more aggressive surgery,
- need for a limited or total thyroidectomy,
- prolonged pain,
- impaired healing,
- and recurrence of the tumor.
Take the Salt QuizDo you love salt? Take the online Salt Quiz to get the facts about dietary salts and sodium in fruits, vegetables, processed foods, snacks and soups!