- High Blood Pressure Slideshow Pictures
- Take the Salt Quiz!
- Lowering Blood Pressure Exercise Tips Pictures
- What is felodipine, and how does it work?
- What brand names are available for felodipine?
- Is this drug available as a generic ?
- Do I need a prescription for it?
- Why doctors prescribe (uses) felodipine?
- What are the side effects of felodipine?
- How should I take this drug (dosage)?
- Which drugs, supplements, or foods interact with felodipine?
- Is it safe to take if I'm pregnant or breastfeeding?
- What else should I know about this drug?
What is felodipine, and how does it work?
Felodipine is an oral calcium channel blocker (CCB) of the dihydropyridine (DHP) class. Other calcium channel blockers in the DHP class include:
- nifedipine (Procardia, Adalat)
- amlodipine (Norvasc)
- nisoldipine (Sular)
- nicardipine (Cardene)
- isradipine (Dynacirc)
Calcium is necessary for muscle cells to contract. Felodipine prevents calcium from being released within the muscle cells of the small arteries and thereby causes the muscles to relax and the arteries to dilate or expand. Dilation of arteries reduces blood pressure. It has little or no effect on the muscles of veins or the heart.
Why doctors prescribe (uses) felodipine?
What are the side effects of felodipine?
The most common side effects reported by patients include:
- Peripheral edema (swollen ankles and feet)
- Increased heart rate
- Low blood pressure
Other important side effects include:
How should I take this drug (dosage)?
- The recommended dose of felodipine is 2.5-10 mg once daily.
- It should be taken without food or with no more than a light meal since food may reduce its absorption.
- Since felodipine comes as a sustained-release tablet, it should be swallowed whole. It should not be chewed or crushed.
Which drugs, supplements, or foods interact with felodipine?
- Cimetidine (Tagamet), ketoconazole (Nizoral, Extina, Xolegel, Kuric), itraconazole (Sporanox), and erythromycin can block the breakdown of felodipine, resulting in higher blood concentrations of felodipine and drops in blood pressure.
- Carbamazepine (Tegretol), phenobarbital, or phenytoin (Dilantin) can lower felodipine blood concentrations. Therefore, higher doses of felodipine may be necessary in patients receiving these medications.
- Taking felodipine with grapefruit juice increases its absorption and may lead to sudden drops in blood pressure.
- Felodipine may increase blood concentrations of tacrolimus (Prograf). Tacrolimus blood concentrations should be monitored and the dose should be modified as necessary.
Is it safe to take if I'm pregnant or breastfeeding?
- There aren't any adequate studies on the effects of felodipine in ppregnant women. Animal studies have shown adverse effects. Therefore, your doctor or health care professional must weigh the potential risks to the fetus against the potential benefits to the you.
- We don't know if felodipine is excreted in breast milk.
What else should I know about this drug?
- It's available as tablets (extended Release) in 2.5, 5, and 10 mg
- You should keep the tablets stored below 86 F (30 C) and protect them from light and moisture.
- Felodipine was approved by the FDA in 1991.
Felodipine (Plendil) is a drug prescribed for the treatment of high blood pressure to prevent heart attack and stroke. Doctors also prescribe it to treat patients for angina, however, it is not an FDA approved drug for this condition.
Common side effects include:
Multimedia: Slideshows, Images & Quizzes
Heart Disease: Causes of a Heart Attack
Learn about heart disease and heart attack symptoms and signs of a heart attack in men and women. Read about heart disease...
High Blood Pressure (Hypertension): Symptoms, Causes, Treatments
What causes high blood pressure (hypertension)? Know the warning signs and symptoms of high blood pressure. Read about high blood...
Sugar Quiz: Facts on Diet & Sugar
Sugar lurks in surprising places. Take the Sugar Quiz to learn of the many ways sugar sneaks into your diet and see what you know...
High Blood Pressure (Hypertension) Quiz: Symptoms, Signs & Causes
Take this quiz and test your IQ of high blood pressure (hypertension), the cardiovascular disease that causes most strokes and...
Salt Quiz: Test Your Diet IQ
Do you love salt? Take the online Salt Quiz to get the facts about dietary salts and sodium in fruits, vegetables, processed...
Heart Disease Quiz: Test Your Medical IQ
Take our Heart Disease Quiz to get answers and facts about high cholesterol, atherosclerosis prevention, and the causes,...
Picture of Hypertension
High blood pressure, defined as a repeatedly elevated blood pressure exceeding 140 over 90 mmHg -- a systolic pressure above 140...
Picture of Blood Pressure
The blood pressure is the pressure of the blood within the arteries. See a picture of Blood Pressure and learn more about the...
Heart Disease: Symptoms, Signs, and Causes
What is heart disease (coronary artery disease)? Learn about the causes of heart disease. Symptoms of heart disease include chest...
Picture of Heart Detail
The heart is composed of specialized cardiac muscle, and it is four-chambered, with a right atrium and ventricle, and an...
Picture of Blood Clot
Blood that has been converted from a liquid to a solid state. See a picture of Blood Clot and learn more about the health topic....
Picture of Heart
The muscle that pumps blood received from veins into arteries throughout the body. See a picture of the Heart and learn more...
Am I Having a Heart Attack? Symptoms of Heart Disease
Heart attacks symptoms vary greatly for men and women, from anxiety and fatigue to nausea and sweating. Learn the warning signs...
How to Lower Blood Pressure: Exercise Tips
Trying to lower high blood pressure (hypertension)? Discover exercises good for lowering blood pressure, along with other...
Heart Health Pictures: How to Lower Triglycerides
Learn 14 ways to lower triglycerides. Learn to keep your heart healthy and triglyceride levels in check with these diet,...
The Benefits of Omega 3 Foods on Heart Health
What are the benefits of omega 3 fatty acids? Learn how Omega 3 rich foods like fish oil, salmon, walnuts, & more can boost brain...
Heart-Healthy Diet: 25 Foods to Protect Your Cardiovascular System
See 25 foods loaded with heart-healthy nutrients that help protect your cardiovascular system. Plus, find easy meal/recipes and...
12 Reasons to Love the Mediterranean Diet in Pictures
The Mediterranean diet is a delicious way to eat healthy. We show you how to get the most from this diet with foods like olive...
Diet for Stress Management: Carbs, Nuts, and Other Stress-Relief Foods
While there are many ways to cope with stress, one strategy is to eat stress-fighting foods. Find out which foods to eat as part...
Vegetarian Diet: Tasty, Basic Choices in Pictures
Thinking about becoming a vegetarian? Compared to the general population, the typical vegetarian has a lower body mass index...
Healthy Seeds: 11 Edible Super Seeds for Better Nutrition
Are pumpkin seeds good for your health? What's the nutritional value of chia seeds? Find out how to easily incorporate more...
Tips to Eat Healthy When You Dine Out in Pictures
Recognize the dangers of eating out and stay on your healthy diet at restaurants. Learn about healthy eating at restaurants,...
Food Swaps for Meals and Snacks for Heart Health in Pictures
Explore 10 food swaps for heart-wise dining. Learn what food to buy and how to cook in order to make a big difference for your...
Related Disease Conditions
How the Heart Works
The heart is a very important organ in the body. It is responsible for continuously pumping oxygen and nutrient-rich blood...
12 Congestive Heart Failure Symptoms, Stages, Causes, and Life Expectancy
Congestive heart failure (CHF) refers to a condition in which the heart loses the ability to function properly. Heart disease,...
Heart Attack Symptoms and Early Warning Signs in Women and Men
Recognizing heart attack symptoms and signs can help save your life or that of someone you love. Some heart attack symptoms,...
Heart disease (coronary artery disease) occurs when plaque builds up in the coronary arteries, the vessels that supply blood to...
High Blood Pressure (Hypertension) Signs, Causes, Diet, and Treatment
High blood pressure (hypertension) is a disease in which pressure within the arteries of the body is elevated. About 75 million...
A heart attack happens when a blood clot completely obstructs a coronary artery supplying blood to the heart muscle. A heart...
Stress and Heart Disease
The connection between stress and heart disease is not clear. Stress itself may be a risk factor, or high levels of stress may...
Angina (Symptoms, Causes, Types, Diagnosis, and Treatment)
Angina is chest pain due to inadequate blood supply to the heart. Angina symptoms may include chest tightness, burning,...
High Blood Pressure Treatment (Natural Home Remedies, Diet, Medications)
High blood pressure (hypertension) means high pressure (tension) in the arteries. Treatment for high blood pressure include...
Omega-3 Fatty Acids (Benefits, Uses, Foods)
Omega-3 fatty acids are essential fats that help decrease one's cholesterol and triglyceride levels as well as reduce the risk of...
Heart Disease in Women
Heart disease in women has somewhat different symptoms, risk factors, and treatment compared to heart disease in men. Many women...
Heart Attacks in Women
Heart disease, particularly coronary artery disease is the leading cause of heart attacks. Women are more likely to die from a...
Heart Attack Treatment
A heart attack involves damage or death of part of the heart muscle due to a blood clot. The aim of heart attack treatment is to...
Febrile seizures, or convulsions caused by fever, can be frightening in small children or infants. However, in general, febrile...
Smoking and Heart Disease
Smoking increases the risk of heart disease in women and men. Nicotine in cigarettes decrease oxygen to the heart, increases...
Vitamins & Exercise: Heart Attack Prevention Series
Vitamins and exercise can lower your risk for heart attack and heart disease. Folic acid, vitamins, and homocysteine levels are...
Heart Attack Prevention
Heart disease and heart attacks can be prevented by leading a healthy lifestyle with diet, exercise, and stress management....
Heart Disease Treatment in Women
Heart disease treatment in women should take into account female-specific guidelines that were developed by the American Heart...
Heart Attack Prevention Overview
Heart attacks are the major causes of unexpected, sudden death among men and women. A heart attack also is a significant cause...
Treatment & Diagnosis
- Sugar FAQs
- High Blood Pressure FAQs
- Heart Disease FAQs
- Salt FAQs
- Medication Disposal
- Dangers of Mixing Medications
- How To Reduce Your Medication Costs
- Pharmacy Visit, How To Get The Most Out of Your Visit
- Indications for Drugs: Approved vs. Non-approved
- Drugs: Buying Prescription Drugs Online Safely
- Drugs: The Most Common Medication Errors
- Grapefruit Juice and Drug Interactions
- Generic Drugs, Are They as Good as Brand-Names?
Medications & Supplements
Prevention & Wellness
Heart Health Resources
Health Solutions From Our Sponsors
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.