- High Blood Pressure Slideshow Pictures
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- What is felodipine, and how does it work?
- What brand names are available for felodipine?
- Is this drug available as a generic ?
- Do I need a prescription for it?
- Why doctors prescribe (uses) felodipine?
- What are the side effects of felodipine?
- How should I take this drug (dosage)?
- Which drugs, supplements, or foods interact with felodipine?
- Is it safe to take if I'm pregnant or breastfeeding?
- What else should I know about this drug?
What is felodipine, and how does it work?
Felodipine is an oral calcium channel blocker (CCB) of the dihydropyridine (DHP) class. Other calcium channel blockers in the DHP class include:
- nifedipine (Procardia, Adalat)
- amlodipine (Norvasc)
- nisoldipine (Sular)
- nicardipine (Cardene)
- isradipine (Dynacirc)
Calcium is necessary for muscle cells to contract. Felodipine prevents calcium from being released within the muscle cells of the small arteries and thereby causes the muscles to relax and the arteries to dilate or expand. Dilation of arteries reduces blood pressure. It has little or no effect on the muscles of veins or the heart.
What brand names are available for felodipine?
Plendil is the brand name available for this drug in the US.
Quick GuideHow to Lower Blood Pressure: Exercise Tips
Do I need a prescription for it?
Yes, you need a prescription from your doctor or health care professional.
Why doctors prescribe (uses) felodipine?
What are the side effects of felodipine?
The most common side effects reported by patients include:
- Peripheral edema (swollen ankles and feet)
- Increased heart rate
- Low blood pressure
Other important side effects include:
How should I take this drug (dosage)?
- The recommended dose of felodipine is 2.5-10 mg once daily.
- It should be taken without food or with no more than a light meal since food may reduce its absorption.
- Since felodipine comes as a sustained-release tablet, it should be swallowed whole. It should not be chewed or crushed.
Which drugs, supplements, or foods interact with felodipine?
- Cimetidine (Tagamet), ketoconazole (Nizoral, Extina, Xolegel, Kuric), itraconazole (Sporanox), and erythromycin can block the breakdown of felodipine, resulting in higher blood concentrations of felodipine and drops in blood pressure.
- Carbamazepine (Tegretol), phenobarbital, or phenytoin (Dilantin) can lower felodipine blood concentrations. Therefore, higher doses of felodipine may be necessary in patients receiving these medications.
- Taking felodipine with grapefruit juice increases its absorption and may lead to sudden drops in blood pressure.
- Felodipine may increase blood concentrations of tacrolimus (Prograf). Tacrolimus blood concentrations should be monitored and the dose should be modified as necessary.
Is it safe to take if I'm pregnant or breastfeeding?
- There aren't any adequate studies on the effects of felodipine in ppregnant women. Animal studies have shown adverse effects. Therefore, your doctor or health care professional must weigh the potential risks to the fetus against the potential benefits to the you.
- We don't know if felodipine is excreted in breast milk.
What else should I know about this drug?
- It's available as tablets (extended Release) in 2.5, 5, and 10 mg
- You should keep the tablets stored below 86 F (30 C) and protect them from light and moisture.
- Felodipine was approved by the FDA in 1991.
Quick GuideHow to Lower Blood Pressure: Exercise Tips
Felodipine (Plendil) is a drug prescribed for the treatment of high blood pressure to prevent heart attack and stroke. Doctors also prescribe it to treat patients for angina, however, it is not an FDA approved drug for this condition.
Common side effects include:
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Medications & Supplements
- nicardipine, Cardene, Cardene SR
- amlodipine, Norvasc
- nifedipine, Adalat (discontinued brand), Procardia, Afeditab, Nifediac
- bepridil (Vascor, Bepadin - Discontinued)
- Drugs: What You Should Know About Your Drugs
- Calcium Channel Blockers (CCBs)
- Drug Interactions
- High Blood Pressure Drugs (Hypertension)
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Top felodipine Related Articles
Angina SymptomsAngina is chest pain due to inadequate blood supply to the heart. Angina symptoms may include chest tightness, burning, squeezing, and aching. Coronary artery disease is the main cause of angina but there are other causes. Angina is diagnosed by taking the patient's medical history and performing tests such as an electrocardiogram (EKG), blood test, stress test, echocardiogram, cardiac CT scan, and heart catheterization. Treatment of angina usually includes lifestyle modification, medication, and sometimes, surgery. The risk of angina can be reduced by following a heart healthy lifestyle.
Congestive Heart Failure (CHF) OverviewCongestive heart failure (CHF) refers to a condition in which the heart loses the ability to function properly. Heart disease, high blood pressure, diabetes, myocarditis, and cardiomyopathies are just a few potential causes of congestive heart failure. Signs and symptoms of congestive heart failure may include fatigue, breathlessness, palpitations, angina, and edema. Physical examination, patient history, blood tests, and imaging tests are used to diagnose congestive heart failure. Treatment of heart failure consists of lifestyle modification and taking medications to decrease fluid in the body and ease the strain on the heart. The prognosis of a patient with congestive heart failure depends on the stage of the heart failure and the overall condition of the individual.
Stress-Reducing FoodsWhile there are many ways to cope with stress, one strategy is to eat stress-fighting foods. Find out which foods to eat as part of a stress management diet.
Heart AttackHeart attack happens when a blood clot completely obstructs a coronary artery supplying blood to the heart muscle. A heart attack can cause chest pain, heart failure, and electrical instability of the heart.
Heart Attack and Atherosclerosis Prevention
Heart disease and heart attacks can be prevented by leading a healthy lifestyle with diet, exercise, and stress management. Symptoms of heart attack in men and women include chest discomfort and pain in the shoulder, neck, jaw, stomach, or back. Women experience the same symptoms as men; however, they also may experience:
- Extreme fatigue
- Pain in the upper abdomen
Leading a healthy lifestyle with a heart healthy low-fat diet, and exercise can help prevent heart disease and heart attack.
Heart Attack Symptoms and Early Warning SignsRecognizing heart attack symptoms and signs can help save your life or that of someone you love. Some heart attack symptoms, including left arm pain and chest pain, are well known but other, more nonspecific symptoms may be associated with a heart attack. Nausea, vomiting, malaise, indigestion, sweating, shortness of breath, and fatigue may signal a heart attack. Heart attack symptoms and signs in women may differ from those in men.
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Heart: How the Heart WorksThe heart is a very important organ in the body. It is responsible for continuously pumping oxygen and nutrient-rich blood throughout your body to sustain life. It is a fist-sized muscle that beats (expands and contracts) 100,000 times per day, pumping a total of five or six quarts of blood each minute, or about 2,000 gallons per day.
High Blood Pressure Hypertension
High blood pressure (hypertension) is a disease in which pressure within the arteries of the body is elevated. About 75 million people in the US have hypertension (1 in 3 adults), and only half of them are able to manage it. Many people do not know that they have high blood pressure because it often has no has no warning signs or symptoms.
Systolic and diastolic are the two readings in which blood pressure is measured. The American College of Cardiology released new guidelines for high blood pressure in 2017. The guidelines now state that blood normal blood pressure is 120/80 mmHg. If either one of those numbers is higher, you have high blood pressure.
The American Academy of Cardiology defines high blood pressure slightly differently. The AAC considers 130/80 mm Hg. or greater (either number) stage 1 hypertension. Stage 2 hypertension is considered 140/90 mm Hg. or greater.
If you have high blood pressure you are at risk of developing life threatening diseases like stroke and heart attack.
REFERENCE: CDC. High Blood Pressure. Updated: Nov 13, 2017.
Take the HBP QuizTake this quiz and test your IQ of high blood pressure (hypertension), the cardiovascular disease that causes most strokes and heart attacks. How are dizziness, snoring, and gout related to HBP? Find the answer and learn how medical treatments and lifestyle adjustments fight this common problem.
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Omega-3 Fatty AcidsOmega-3 fatty acids are essential fats that help decrease one's cholesterol and triglyceride levels as well as reduce the risk of coronary artery disease. Omega-3s are found in:
- walnuts, and
- canola oil.
ParathyroidectomyParathyroidectomy is the removal of one or more of the parathyroid glands to treat hyperparathyroidism. Risks of parathyroidectomy include:
- paralysis of the vocal cords,
- difficulty swallowing thin liquids,
- difficulty breathing,
- and drug reactions.
- damage to the recurrent laryngeal nerve,
- bleeding or hematoma,
- problems maintaining calcium levels in the blood,
- need for further and more aggressive surgery,
- need for a limited or total thyroidectomy,
- prolonged pain,
- impaired healing,
- and recurrence of the tumor.
Stress and Heart DiseaseThe connection between stress and heart disease is not clear. Stress itself may be a risk factor, or high levels of stress may make risk factors for heart disease worse. The warning signs of stress can be physical, mental, emotional, or behavioral. Reducing stressors in an individuals life not only can lead to a more productive life, but may also decrease the risk for heart disease and causes of heart disease.
Take the Sugar QuizSugar lurks in surprising places. Take the Sugar Quiz to learn of the many ways sugar sneaks into your diet and see what you know about sugar and artificial sweeteners!
Vegetarian DietThinking about becoming a vegetarian? Compared to the general population, the typical vegetarian has a lower body mass index (BMI), lower cholesterol, reduced risk of type 2 diabetes and coronary artery disease. Here are some nutritious and satisfying vegetarian foods to get you started.