Medical Definition of Eye color

Reviewed on 3/29/2021

Eye color: The color of the iris. The genetics of eye color are complicated. Eye color is polygenic. It is determined by multiple genes. The eye color genes include EYCL1 (a green/blue eye color gene located on chromosome 19), EYCL2 (a brown eye color gene) and EYCL3 (a brown/blue eye color gene located on chromosome 15). There are clearly other genes that influence eye color. The once-held view that blue eye color is a simple recessive trait has been shown to be wrong. The genetics of eye color are so complex that almost any parent-child combination of eye colors can occur.

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