Erythema Nodosum: Symptoms & Signs

Medically Reviewed on 1/14/2022

Erythema nodosum is a type of skin inflammation that is most commonly seen on the front surfaces of the lower legs (shins).

Signs and symptoms of erythema nodosum include

Other associated symptoms and signs can include enlarged lymph nodes in the chest and bruising on the shins. The nodules on the shins can come and go over a period of weeks to months. When the nodular areas have gone away, a bruised appearance to the skin may remain.

Causes of Erythema Nodosum

The condition can occur on its own or may develop in relation to other conditions, including pregnancy, infections such as mononucleosis, cat scratch disease, fungal infections, inflammatory bowel diseases, and sarcoidosis. The condition can also be related to certain medications.

Other erythema nodosum symptoms and signs


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Jameson, J. Larry, et al. Harrison's Principles of Internal Medicine, 20th Ed. New York: McGraw-Hill Education, 2018.