- 10 Common Allergy Triggers Slideshow Pictures
- Take the Quiz on Allergies
- Nasal Allergy Relief Products Slideshow
- What is epinephrine injection Auvi-Q, and how does it work (mechanism of action)?
- What brand names are available for epinephrine injection Auvi-Q?
- Is epinephrine injection Auvi-Q available as a generic drug?
- Do I need a prescription for epinephrine injection Auvi-Q?
- What are the side effects of epinephrine injection Auvi-Q?
- What is the dosage for epinephrine injection Auvi-Q?
- Which drugs or supplements interact with epinephrine injection Auvi-Q?
- Is epinephrine injection Auvi-Q safe to take if I'm pregnant or breastfeeding?
- What else should I know about epinephrine injection Auvi-Q?
What is epinephrine injection Auvi-Q, and how does it work (mechanism of action)?
Auvi-Q is an auto-injectable epinephrine-containing device used for self-administration during life-threatening allergic reactions, including anaphylaxis. Auvi-Q is an epinephrine auto-injector that talks the user step by step through the injection process. Epinephrine, the medicine contained in Auvi-Q, is an excitatory chemical naturally made by our bodies. Epinephrine stimulates alpha and beta adrenergic receptors found throughout the body. When injected during an allergic reaction, epinephrine works in multiple ways to treat the many signs of anaphylaxis. It causes blood vessels to constrict or tighten which helps to increase blood pressure and decrease swelling. Epinephrine also stimulates the heart muscle, causing the heart to beat faster and pump more blood to the vital organs. Epinephrine helps patient's breathe better by relaxing the muscles in the lungs and allowing the airways to open up. Additionally, it also helps to prevent further release of inflammatory chemicals that were triggered by the initial allergic reaction.
Auvi-Q was approved by the FDA in 2012.
Is epinephrine injection Auvi-Q available as a generic drug?
GENERIC AVAILABLE: Although auto-injectable epinephrine is available in generic forms, a generic version of Auvi-Q device is currently not available.
What are the side effects of epinephrine injection Auvi-Q?
The most common side effects of Auvi-Q include:
- fast, irregular, or pounding heartbeat;
- vomiting; and
- breathing problems.
Auvi-Q is intended for administration in the muscle or fat tissues in the outer thigh only. Injecting Auvi-Q in other areas of the body including the buttocks, hands, or feet may not provide effective treatment of anaphylaxis and may even cause side effects.
Quick GuideBad Bugs: Identify Bug Bites From Mosquitos, Spiders and More
What is the dosage for epinephrine injection Auvi-Q?
Auvi-Q is available in two strengths, 0.15 mg and 0.3 mg. The selection of the appropriate strength is based on the patient's body weight. Patients weighing = 30 kg (approximately = 66 pounds) should use Auvi-Q 0.3 mg. Patients weighing 15 to 30 kg (approximately 33 to 66 pounds) should use Auvi-Q 0.15 mg. It is not known if Auvi-Q is safe and effective for use in children weighing less than 15 kg (33 pounds).
Each device contains only 1 dose of medicine and can only be used once. Auvi-Q should be injected into the muscle of the outer thigh. If needed, Auvi-Q may be injected through clothing.
Which drugs or supplements interact with epinephrine injection Auvi-Q?
Administration of epinephrine to patients taking cardiac glycosides, diuretics (water pills), or drugs for treating irregular heartbeats (antiarrhythmics) can cause the development of irregular heartbeats.
The treatment benefits of epinephrine can be reduced by beta-adrenergic blocking medicines such as propranolol (Inderal) and alpha-adrenergic blocking medicines such as phentolamine (Regitine, OraVerse).
Some anti-migraine medications may also interfere with the benefits of epinephrine treatment.
Patients should speak with their pharmacist for a complete list of all drug interactions, and check if any of their current medications have any meaningful interactions with Auvi-Q.
Is epinephrine injection Auvi-Q safe to take if I'm pregnant or breastfeeding?
Use of epinephrine has not been adequately evaluated in pregnant women. Use of epinephrine in animal studies was associated with birth defects. Epinephrine should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Epinephrine is classified as FDA pregnancy risk category C (animal studies show an adverse effect on the fetus).
It is not known if epinephrine is excreted in breast milk. Since many drugs are excreted in human milk and have the potential of causing harm to the nursing infant, caution should be used when Auvi-Q is administered to a nursing mother.
What else should I know about epinephrine injection Auvi-Q?
What preparations of epinephrine injection Auvi-Q are available?
Injection: 0.3 mg (0.3 mg/0.3ml) and 0.15 (0.15 mg/0.15 ml) prefilled auto injector.
How should I keep epinephrine injection Auvi-Q stored?
Auvi-Q should be stored at room temperature, between 15 C and 30 C (59 F to 86 F). Auvi-Q should not be refrigerated. The medicine contained in Auvi-Q is light sensitive and should be protected from the light. Auvi-Q should always be stored in the outer case provided by the manufacturer.
REFERENCE: FDA Prescribing Information
Quick GuideBad Bugs: Identify Bug Bites From Mosquitos, Spiders and More
A self-administered epinephrine injection (Auvi-Q) is a prescription medication used in emergencies by people with severe allergies to halt anaphylaxis. Side effects, drug interactions, and patient safety information should be reviewed prior to taking this medication
Multimedia: Slideshows, Images & Quizzes
Allergies Quiz: Symptoms & Home Remedies
What are the causes of allergies? This online quiz challenges your knowledge of common food and household allergens,...
Picture of Eye Allergies
Severe allergic eye symptoms can be very distressing and are a common reason for visits to the allergist or ophthalmologist. See...
When Animal (Allergies) Attack: Pet Allergy Symptoms, Treatment
How do you control and relieve pet allergies? How do you prevent pet allergies? Learn dog and cat allergy symptoms, the cause of...
10 Worst Cities for Spring Allergies With Pictures
See pictures of the top 10 "spring allergy capitals", according to the Asthma and Allergy Foundation of America (AAFA). From...
Out-of-Control Allergy Symptoms: Treatment Relief in Pictures
Learn 10 signs your allergies are out of control. See these surprising allergy symptoms and find out how to get relief for...
Related Disease Conditions
Food Allergies: When Food Becomes the Enemy
Second Source article from Government...
Insect Sting Allergies
The majority of stinging insects in the United States are from bees, yellow jackets, hornets, wasps, and fire ants. Severity of...
An allergy refers to a misguided reaction by our immune system in response to bodily contact with certain foreign substances. ...
Anaphylaxis is a serious allergic reaction that affects a number of different areas of the body at one time, and can be fatal....
About 1% to 2% of people in the U.S. have a peanut allergy. Symptoms and signs of a peanut allergy include rash, hives, redness,...
Fragrances and preservatives in cosmetics may cause allergic reactions in some people. Symptoms include redness, itching, and...
Drug Allergy (Medication Allergy)
Drug or medication allergies are caused when the immune system mistakenly creates an immune response to a medication. Symptoms of...
Treatment & Diagnosis
Medications & Supplements
Prevention & Wellness
- Options Increasing for Coping With Kids' Food Allergies
- Options Increasing for Coping With Kids' Food Allergies
- Bullied Over Food Allergies
- African-American Kids May Have More Food Allergies
- Black Male Children Have Highest Rates of Food Allergies
- Don't Let Food Allergies Spoil the Picnic
- Rate of Childhood Peanut Allergies More Than Triples
- Kids With Food Allergies May Need 2 EpiPens
- Kids' Peanut Allergies Might Be Tamed: Study
- Child Food Allergies on the Rise in U.S.
- Black Male Children Face Highest Risk for Food Allergies
- Sesame Allergies on the Rise in U.S.
- New Ways to Fight Nut, Milk Allergies
- Students Inattentive to Food Allergies
- Progress Against Peanut Allergies
Daily Health News
Subscribe to MedicineNet's Allergy and Asthma Newsletter
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Top epinephrine injection Auvi-Q Related ArticlesComplete List
Take the Allergies QuizWhat are the causes of allergies? This online quiz challenges your knowledge of common food and household allergens, environmental triggers, allergic diseases and conditions, and allergy symptoms and treatments.
AllergyAn allergy refers to a misguided reaction by our immune system in response to bodily contact with certain foreign substances. When these allergens come in contact with the body, it causes the immune system to develop an allergic reaction in people who are allergic to it. It is estimated that 50 million North Americans are affected by allergic conditions. The parts of the body that are prone to react to allergies include the eyes, nose, lungs, skin, and stomach. Common allergic disorders include hay fever, asthma, allergic eyes, allergic eczema, hives, and allergic shock.
AnaphylaxisAnaphylaxis is a serious allergic reaction that affects a number of different areas of the body at one time, and can be fatal. Causes of anaphylaxis can be food allergy, latex allergy, allergy to insect or but stings/bites, asthma, or other materials or conditions. Symptoms include flushing, itching, hives, anxiety, rapid or irregular pulse. Severe symptoms may be throat and tongue swelling, swallowing, and difficulty breathing. Some disorders appear similar to anaphylaxis such as fainting, panic attacks, blood clots in the lungs, heart attacks, and septic shock. If you think that you may be having an anaphylactic reaction, seek emergency care or call 911 immedately.
Cosmetic AllergiesFragrances and preservatives in cosmetics may cause allergic reactions in some people. Symptoms include redness, itching, and swelling after the product comes in contact with the person's skin. Treatment typically involves the use of over-the-counter cortisone creams.
Periactin (brand name) cyproheptadine (generic name) is an antihistamine used to treat allergic reactions by blocking the histamines. The drug is used to for various types of allergic reactions including skin reactions. Off-label (non-FDA approved uses) include spasticity associated with spinal cord injury and preventing migraine headaches. There are numerous side effects of this medication and some include:
- Blurred vision
- Double Vision
- Ringing in the ears
- Urinary retention
Dosing, drug and supplement interactions, and pregnancy and breastfeeding safety should be reviewed prior to taking this drug.
Drug or medication allergies are caused when the immune system mistakenly creates an immune response to a medication. Symptoms of a drug allergic reaction include:
- Itchy skin or eyes
The most common drugs that people are allergic to include:
- Penicillins and penicillin type drugs
- Sulfa drugs
Treatment may involve antihistamines or corticosteroids. An Epipen may be used for life-threatening anaphylactic symptoms.
EpiPen and EpiPen Jr (epinephrine injection, autoinjector) is a prescription drug used for the emergency treatment of allergic reactions. Side effects of EpiPen include:
- Pale skin
Drug interactions, dosage, and pregnancy and breastfeeding safety information should be reviewed prior to using this drug.
Eye Allergies PictureSevere allergic eye symptoms can be very distressing and are a common reason for visits to the allergist or ophthalmologist. See a picture of Eye Allergies and learn more about the health topic.
Insect Sting AllergiesThe majority of stinging insects in the United States are from bees, yellow jackets, hornets, wasps, and fire ants. Severity of reactions to stings varies greatly. Avoidance and prompt treatment are essential. In selected cases, allergy injection therapy is highly effective.
Allergies SlideshowLearn 10 signs your allergies are out of control. See these surprising allergy symptoms and find out how to get relief for sneezing, congestion, watery eyes, and more.
Peanut AllergyAbout 1% to 2% of people in the U.S. have a peanut allergy. Symptoms and signs of a peanut allergy include rash, hives, redness, and itching. Severe reactions may cause difficulty breathing, nausea, decreased blood pressure, lightheadedness, and behavioral changes. People with a peanut allergy should carry an epinephrine auto-injector with them at all times.
Pets & AllergiesHow do you control and relieve pet allergies? How do you prevent pet allergies? Learn dog and cat allergy symptoms, the cause of allergies to cats and dogs, how to clean up for pet allergies, and the truth about hypoallergenic dogs and cats. Discover how to treat symptoms of pet allergies.
Worst Allergy CitiesSee pictures of the top 10 "spring allergy capitals", according to the Asthma and Allergy Foundation of America (AAFA). From coast to coast, see if your city made the top 10.