- Deep Vein Thrombosis Slideshow Pictures
- Take the DVT and PE Quiz
- Spider & Varicose Veins Pictures Slideshow
- What brand names are available for enoxaparin?
- Is enoxaparin available as a generic drug?
- Do I need a prescription for enoxaparin?
- What are the uses for enoxaparin?
- What are the side effects of enoxaparin?
- What is the dosage for enoxaparin?
- Which drugs or supplements interact with enoxaparin?
- Is enoxaparin safe to take if I'm pregnant or breastfeeding?
- What else should I know about enoxaparin?
What are the uses for enoxaparin?
- Lovenox is used for preventing deep vein thrombosis after abdominal surgery, or hip or knee replacement surgeries, and in patients with reduced mobility due to illness.
- It is used both in and out of the hospital for treating deep vein thrombosis and pulmonary embolism.
- Lovenox also is used for preventing a second heart attack and related complications after a heart attack and for preventing blood clots in arterial stents.
What are the side effects of enoxaparin?
Common side effect associated with Lovenox are:
Other possible side effects include:
- Abnormal liver tests in the blood
- Mild local irritation
- Local injection site reaction
Possible serious side effects include:
Quick GuideDVT in Pictures: Symptoms of Deep Vein Thrombosis, Beyond Leg Pain and More
What is the dosage for enoxaparin?
Lovenox is administered by injection under the skin (subcutaneous) or intravenously.
- Preventing deep vein thrombosis after abdominal surgery: 40 mg subcutaneous injection once daily.
- Preventing deep vein thrombosis after knee replacement: 30 mg subcutaneous injection every 12 hours.
- Preventing deep vein thrombosis after hip replacement: 30 mg every 12 hours or 40 mg once daily by subcutaneous injection.
- Preventing deep vein thrombosis in ill patients with limited mobility: 40 mg subcutaneous injection once daily.
- Treatment of deep vein thrombosis or pulmonary embolism: 1 mg/kg every 12 hours or 1.5 mg/kg once daily by subcutaneous injection.
- Outpatient treatment of deep vein thrombosis: 1 mg/kg subcutaneous injection every 12 hours.
- Treatment of severe heart attacks (ST elevation myocardial infarction or STEMI): For patients under the age of 75, 30 mg intravenously plus 1 mg/kg subcutaneously followed by 1 mg/kg every 12 hours (maximum of 100 mg for each of the first two subcutaneous doses only). For patients over age 75, 0.75 mg/kg subcutaneously every 12 hours (maximum of 75 mg for each of the first two subcutaneous doses only). All patients should receive aspirin. Doses should be reduced in patients with impaired kidney function.
- Treatment of chest pain (unstable angina) or mild heart attack (non-Q-wave myocardial infarction): 1 mg/kg subcutaneously every 12 hours with aspirin.
- For coronary artery stent procedures (percutaneous coronary intervention or PCI): Patients should receive 0.3 mg/kg during stent placement if the last dose of Lovenox was administered more than 8 hours before the procedure.
Which drugs or supplements interact with enoxaparin?
- Medications that increase the risk of bleeding will add to the effects of Lovenox and further increase the risk of bleeding that is associated with Lovenox. Such medications include aspirin, clopidogrel (Plavix), warfarin (Coumadin), other anticoagulants, and nonsteroidal anti-inflammatory drugs such as ibuprofen (Motrin; Advil), naproxen (Naprosyn), diclofenac (Voltaren), and others.
Is enoxaparin safe to take if I'm pregnant or breastfeeding?
- Lovenox does not cross the placenta and shows no evidence of effects on the fetus. It often is used during pregnancy as an alternative to oral anticoagulants such as warfarin (Coumadin), which cannot be safely used during pregnancy.
- Lovenox multiple-dose vials contain benzyl alcohol as a preservative. Benzyl alcohol has been associated with a fatal "gasping syndrome" in premature neonates. Lovenox vials preserved with benzyl alcohol should be used with caution in pregnant women and only if clearly needed because benzyl alcohol may cross the placenta.
- It is not known if Lovenox is excreted in breast milk. Since most medicines are excreted in breast milk, it is recommended that women receiving Lovenox should not breastfeed.
What else should I know about enoxaparin?
What preparations of enoxaparin are available?
- Lovenox is available in pre-filled syringes containing 30, 40, 60, 80, 100, 120, and 150 mg.
- Multiple dose vial: 300 mg
How should I keep enoxaparin stored?
All Lovenox products should be stored at room temperature, between 15 and 30 C (59 and 86 F).
Lovenox (enoxaparin) is a medication prescribed for preventing deep vein thrombosis (DVT) and pulmonary embolism after surgeries such as abdominal, hip or knee replacement, and in patients with reduced mobility due to illness. Lovenox is also prescribed to prevent a second heart attack and related complications after a heart attack, and for preventing blood clots in arterial stents. Side effects include
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Treatment & Diagnosis
Medications & Supplements
Prevention & Wellness
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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Blood ClotsBlood clots can occur in the venous and arterial vascular system. Blood clots can form in the heart, legs, arteries, veins, bladder, urinary tract and uterus. Risk factors for causes of blood clots include high blood pressure and cholesterol, diabetes, smoking, and family history.
Symptoms of a blood clot depend on the location of the clot. Some blood clots are a medical emergency. Blood clots are treated depending upon the cause of the clot. Blood clots can be prevented by lowering the risk factors for developing blood clots.
Coronary AngioplastyBalloon angioplasty of the coronary artery and stents (percutaneous coronary intervention, PCI) is a non-surgical procedure that relieves narrowing and obstruction of the arteries to the muscle of the heart. PCI can relieve chest pain (angina), minimize or stop a heart attack, or improve the prognosis of patients with unstable angina. The availability of stainless steel stents have expanded the spectrum of patients suitable for PCI.
Deep Vein Thrombosis
Deep vein thrombosis (DVT) is a blood clot in the deep veins, and can be caused by broken bones, trauma to a limb, immobility, medications, smoking, cancer, genetic predisposition, and cancer. Symptoms of a deep vein thrombosis in a leg are swelling, tenderness, redness, warmth, and pain.
Treatment for DVT include medications and surgery.
Take the DVT QuizTake the Deep Vein Thrombosis and Pulmonary Embolism Quiz to learn causes, symptoms, and treatments for these two dangerous conditions.
DVT SlideshowDeep vein thrombosis (DVT) is a dangerous and sometimes fatal blood clot that occurs deep within the lower leg or thigh. Understand the symptoms, treatment and prevention of deep vein thrombosis (DVT).
Heart Disease (Coronary Artery Disease)
Heart disease (coronary artery disease) occurs when plaque builds up in the coronary arteries, the vessels that supply blood to the heart. Heart disease can lead to heart attack. Risk factors for heart disease include:
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Heart: How the Heart WorksThe heart is a very important organ in the body. It is responsible for continuously pumping oxygen and nutrient-rich blood throughout your body to sustain life. It is a fist-sized muscle that beats (expands and contracts) 100,000 times per day, pumping a total of five or six quarts of blood each minute, or about 2,000 gallons per day.
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Pulmonary EmbolismA pulmonary embolism (PE) occurs when a piece of a blood clot from deep vein thrombosis (DVT) breaks off and travels to an artery in the lung where it blocks the artery and damages the lung. The most common symptoms of a pulmonary embolism are shortness of breath, chest pain, and a rapid heart rate. Causes of pulmonary embolism include prolonged immobilization, certain medications, smoking, cancer, pregnancy, and surgery. Promt medical attention should be sought if you think you or someome you know has a pulmonary embolus.
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Surgery QuestionsSurgery is the branch of medicine that employs operations in the treatment of disease or injury. Prior to surgery you might consider asking your surgeon questions about the operation (procedure).
Total Hip ReplacementDuring total hip replacement, diseased hip cartilage and bone is replaced with artificial materials. Risks of the surgery include blood clots in the lower extremities, difficulty with urination, infection, bone fracture, scarring, limited range of motion, and prosthesis failure.
Total Knee ReplacementDuring total knee replacement surgery, the diseased knee joint is replaced with artificial material. The risks include blood clots in the legs, urinary tract infection, nausea and vomiting, chronic knee pain, nerve damage, and infection.