Patient Comments: Endometrial Biopsy - Experience

Question:

Have you had an endometrial biopsy? Please describe your experience. Submit Your Comment

Comment from: Scoundrel, 45-54 Female (Patient) Published: November 15

I was terrified of endometrial biopsy after having read the comments everywhere. I had a uterine ultrasound today by a doctor in his office to check on a fibroid I've had for a while. Before I knew what was going on he said he wanted to do a biopsy. I said I'd heard horror stories and asked if it was necessary, and he said it's better to rule out cancer despite fibroids being benign. I had taken no pain reliever or sedative. I knew what to expect, when he asked me to cough I knew he was putting on a cervix clamp. I could feel it but it did not hurt at all. Then the dilation was like cramps, no pain or stabbing, honestly it was worse lying there expecting pain. Then I felt him taking the sample, it was a tiny ache but believe me I've had worse pain thumping my head on a cupboard or something. I have had much worse periods. Well, after that he said it was over and that was it. It was overall like a medium-bad period and only lasted a few minutes. I'm not sure if he used any numbing agent on my cervix or not but if he did he was fast. I worried for nothing and have it behind me. Now, I was very hot and flushed so they had me lie back for a bit, and after I left I felt queasy like I could vomit but didn't. I did have some bleeding this afternoon but they gave me a pad. But that was it. The dreaded test is over and we can rule out cancer and any worries.

Comment from: Nessie150, 55-64 Female (Patient) Published: November 08

I have just had an endometrial biopsy. Well, I almost had one, had to decline halfway through as pain was too much. I had knife-like burning, no cramping just a hotness. I had a smear done prior and no problems, going for a scan now. Hopefully I will not be recalled as I am not sure I could go through this without something.

Comment from: mommafluff, 45-54 Female (Patient) Published: October 27

I had a sonohysterogram and endometrial biopsy yesterday. I too was very nervous about the procedure. I was advised to take 4 ibuprofen 1 hour prior to the test. I opted to take hydrocodone that I had left over from a past procedure, which I did tell the doctor about when I got in the exam room. Sonohysterogram didn't feel any more uncomfortable than a normal internal ultrasound. Just pressure, no pain. I asked questions of the doctor the whole time he was preparing to do the biopsy, especially when I could expect to feel the most pain. He was really great at telling me every step made, and when it was going to hurt the most. Speculum was in the furthest I think it could go! Not so much pain as discomfort. The catheter was inserted easily, and painlessly. The sonohysterogram was fine, a little cramping when the saline was injected, not more than period cramping. Then he did say that the biopsy would hurt, which it did. But definitely not unbearable, just pinchy. I have had worse pain stubbing a toe. He counted down how long it was going to take which was great, because when you have an end in sight you can get through it! Removal of the instrument also caused a little cramping. Hardly any spotting, and no after cramps, just a little sore if I pressed on my pelvic area, like a bruise. I don't know if it was the stronger pain medicines I took that made it easier than others have stated. But, it also helped me to talk during the whole procedure with the doctor and nurse in the room.

Comment from: edbk35, 55-64 Female (Patient) Published: October 20

I had endometrial biopsy yesterday. I had read all the reviews that other women had posted on various forums and had totally freaked out about it. I was so worried and dreaded it so badly. I mean some of the posts were horrible and so scary. However, it was not bad at all. I just turned 55 on Tuesday. I had this the next day. I was given a pill to insert the night before to help with softening of my uterus. I have had 3 children the last one in 1998. I dreaded the clamp for the cervix if it was needed and yes, I got the clamp too. It was just a pinch. Yes, I felt it when she inserted the device to collect the samples and yes, there was a bit of cramping and mostly pressure like it was deep inside, but my doctor was great with telling me every step of the way what she was doing. When she was in there getting samples she told me that what I was feeling was the absolute worse part. It was just a lot of pressure. So I knew at that point that was all I had to deal with. I also brought a stress ball. It was just a squishy ball to squeeze in my hand. I also took four 200 mg. of Motrin about an hour before my procedure. I had some light bleeding yesterday and a tinge of spotting this morning. I did take Tylenol 4 hours after the 800 mg of Motrin and I took 800 mg of Motrin last night with dinner. Now I get to worry about the results which I should hear back in a week. From start to finish I was probably in the exam room 15 minutes. The actual procedure was a few minutes from start to finish. I feel a little uncomfortable down there today, but I haven't take any Motrin or Tylenol. If I had to do this again, I would be completely fine. Good luck!

Comment from: veme, 35-44 Female (Patient) Published: October 19

My endometrial biopsy was done due to abnormal incessant bleeding. I am 37, and have not had children so far. I knew beforehand there would be cramping, so I thought I was prepared for that. But I was not. Although it was brief (1 minute or so), it hurt like crazy, I was crying and breathing as much as I could. I got nauseated and light-headed from the pain and thought I would pass out. Now 3 hours after the procedure I don't want to move, just on pain medicines, and I can feel the blood accumulating in my pants. I'd only do this again with opioids, before and after the procedure. Awful!

Comment from: Christina, 45-54 Female (Patient) Published: October 04

The uterine lining biopsy was horrible! I was not advised to take any NSAIDs or a pad. I have not had any children so I had to be dilated to get the cervix open. I felt a lot of pressure, bad cramping and a searing poker or needle going through me! Although it was not long, it felt like an eternity! I moaned and groaned the whole way through the endometrial biopsy. I also had a tight grip on the edges of the examining table. The gynecologist kept telling me how well I did. Then, when I was going to get up and get dressed, the doctor told me to lie back down for a little longer because of vasovagal syncope. I assume I must have been pale. I bled for a few days afterwards. I would not go through this again without some strong drugs!

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Comment from: Tress, 55-64 Female (Patient) Published: September 19

Well, I am a first timer of endometrial biopsy, no prior understanding of procedure. They had to clamp a 'jumpy uterus', still okay, but then, during the second tissue collection, there was a moment of 'no way!' Just like the line crossed, when giving birth, there was intense pain. It was afterwards that one is not prepared too. Similar to my stereotactic breast biopsy, where you roll over, catch a good breath and weep. To be a woman!

Comment from: Callie, 35-44 Female (Patient) Published: September 08

I wanted to add my experience(s) given most of these seem to fit my first experience, but not my second. The first time I had the endometrial biopsy I had 1 child already, but a C-section. I had taken 3 ibuprofen prior and the first part of the procedure (getting past the cervix) was awful. Many attempts, and I very well may have cried. Once doctor was past that point, the rest of the procedure was fine! Felt weird, but not painful. The second time around, last week, I was really freaked out ahead of time (and I read these stories on top of remembering my previous experience). I was not able to take ibuprofen, but took 2 Tylenol. Also, I had a second child a few years back, not a C-section. I think that made the difference. No problem with the cervix, and the other part of biopsy was fine again. So, I am not sure if it will ease some people's minds; it is possible for this to not hurt, or minimally be uncomfortable. Wish it could be that way for all.

Comment from: JerryLynn, 35-44 Female (Patient) Published: September 07

I just had my first endometrial biopsy. I read all the stuff on here and was scared to death. Anyway, I took 3 Aleve and a tramadol 1 hour 15 minutes before my appointment time and it wasn't nearly as bad as I thought it would be. Procedure was, put gown on, spread legs, scooch down, regular speculum clamp, cough while she put in second cervix clamp; a few samples were suctioned and she removed both clamps and it was over. The cervical clamp was painful (I moaned and tensed up a bit) but it was doable. That was probably the worst part of it. The sample taking was easy (suctioning was it). So, it was about 2 to 3 minutes of pain, then it was over. A little sore. I relaxed for a couple of hours until the tramadol wore off. Then I was out food shopping with no problem. Moral of story, take pain killer prior to appointment.

Comment from: Gina, 45-54 Female (Patient) Published: August 22

I had an endometrial biopsy yesterday. It was the most painful thing I have ever experienced. I have had a few colposcopies, and an HSG (hysterosalpingogram). Neither hurt as much. The pain was sudden and short lived but goodness! I did not expect how painful it would be. I have not had any children so insertion was very painful as was the collection. Ask if you can get something to numb the pain and I would suggest Advil or something an hour before.

Comment from: Erin, 45-54 Female (Patient) Published: August 10

I had an endometrial biopsy today and took ibuprofen. The first 2 attempts using a pipette were slightly uncomfortable but very tolerable. Unfortunately they didn't get what they needed and had to clamp my cervix to try again. The clamp was excruciating when it was placed, I screamed as it went on. It continued to cause some pain for the rest of the procedure and was almost as painful when it was removed. They tried 3 more times with the pipette and only managed to get a tiny sample which may not be enough to test. The pipette itself caused more pain after clamp was placed and my quick procedure took about 30 minutes and may not get any results. I am 9 hours post procedure and having very little bleeding but have bad cramps and some pain in the area of my cervix. If your doctor can safely do the procedure without clamping the cervix, have them try that first as it was the clamp that caused the majority of my pain.

Comment from: Benny, 55-64 Female (Patient) Published: August 04

I'm 59, and had an impromptu endometrial biopsy last week, so no medications taken ahead of time. Because I've had 4 C-sections and no vaginal deliveries, my cervix was extremely tight and difficult to get through, requiring multiple attempts to do the biopsy. The pain was excruciating! I usually have a high pain tolerance, but this was unlike anything I've experienced before. I felt traumatized afterwards, and will never go through this again without sedation!

Comment from: madge, 55-64 Female (Patient) Published: July 27

I had an ultrasound for prolonged bleeding last week, following my annual checkup. After completing the ultrasound, I was told to get dressed and the doctor would talk to me. After dressing and moving into a different room, the nurse came back in and told me to undressed again, that they would be doing an endometrial biopsy. Stupid me, I was totally unprepared and didn't even know what they were looking for. I must say, while short lived, I thought the pain was excruciating. It was over within a minute, I am sure, but afterwards, I burst into tears.

Comment from: Nanna?C, 45-54 Female (Patient) Published: July 19

I received a uterine biopsy last week. During the endometrial biopsy there was pain but it wasn't horrible, however it was more painful than expected. There is a memory of someone yelling, 'what the heck'; yes that person was me. However afterwards during the post-surgical discussion with my doctor and husband all the severe pain had already subsided. There was discomfort for four days when I bent sideways or moved around too much. I received my all clear status yesterday! The tumor is not cancerous.

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Comment from: alibaba, 45-54 Female (Patient) Published: July 14

I had an appointment with a gynecologist today and did not expect to be having an endometrial biopsy. So no idea beforehand of what to expect and no pain relief taken. This test needs re-thinking and by a woman. Brutal. I had 10 seconds of sheer agony. I broke out into a sweat and felt light headed only to be told another sample was needed; a count of 5. This was worse as I knew what was coming. I came home and took maximum pain relief and I'm still griping 2 hours later. The consultant and nurse were both extremely lovely, the procedure however was possibly the worst pain ever. It's a 9.5 if not a 10.

Comment from: Dorothy, 55-64 Female (Patient) Published: July 11

My doctor attempted to do an endometrial biopsy years ago. It was the worst pain I ever experienced in my life and I've experienced a lot of pain. I begged her to stop and she did. Now since I'm showing lots of signs of uterine cancer they scheduled me for another endometrial biopsy. I prepared this time by taking several Tylenol and codeine plus anti-anxiety drugs. Again it was the worst pain I ever felt and the doctor could not do the procedure. She recommended that I just have a hysterectomy because I will simply be asleep and feel no pain. I will be having a hysterectomy soon.

Comment from: Dms, 55-64 Female (Patient) Published: June 29

I just had an endometrial biopsy today for post-menopausal bleeding. I took 400 mg of ibuprofen 1 hour before. My doctor inserted the tube and started counting to 10. There was some minor pain and a few cramps, but that was it. Sorry others had a harder time, depends on the length of the procedure and number of samples needed.

Comment from: armywife, 55-64 Female (Patient) Published: June 16

I had an endometrial biopsy (EB) when I was 40. I took Motrin ahead of time as directed which am not sure that helped or not! It took several minutes and the pain was tolerable but I still broke out in a sweat and felt nauseated when it was over but that passed quickly. Second EB done when I was 58. One word comes to mind; barbaric! It was extremely painful, I almost passed out. They gave me a shot of Toradol after the EB. I will never have this procedure again unless sedated.

Comment from: catfang, 55-64 Female (Patient) Published: June 15

I had a follow up appointment with my doctor because what she previously prescribed had not taken any effect on me. To my surprise, the nurse said given my current symptoms, she will prepare me for an endometrial biopsy. She explained the procedure and I immediately got nervous. Then the doctor came in and assured me it would not take long and would go step by step so I knew what she was doing. She was very good in trying to relax me and went step by step. However, no prepping in the world prepared me for the pain I was going to experience. I'm sure the whole area heard my yells. It felt like I was being ripped inside. Thankfully it was over in a few minutes but those were the longest minutes in my life.

Comment from: FrannyBlue, 45-54 Female (Patient) Published: June 15

I just had an endometrial biopsy today. It wasn't bad at all. Maybe it depends on your obstetrician/gynecologist's experience. It's not fun, but I'd estimate that the whole procedure took about 5 minutes from the time my doctor walked into the room. I've never had children, so my cervix is probably a bit narrower, but mostly I feel like I have some menstrual cramps and that's it.

Comment from: Riblet2017ad, 35-44 Female (Patient) Published: June 15

I never had any problems until January 2017. I started a heavy cycle and was told to get an ultrasound. It showed I have a cyst on my right ovary and many fibroids. I was asked to come in for an endometrial biopsy. I too read that it would feel like cramping. I took my ibuprofen an hour in advance. I'll be honest, it was uncomfortable in the beginning. My doctor was up to 6 samples with cramps happening. Now this is the part where I felt my guts were being ripped out; and we had 9 more samples to be taken. There was no scraping, it was an electronic suction and each time she counted it got worse to excruciating. I was literally was squeezing the life out the nurse's hand, and on number 13 no amount of pain killer would numb that. So if anyone who needs to have this biopsy ask how many samples they will take. And with what surgical instrument. Beyond 8, I would rather be anesthetized. I have had my foot caught in a motorcycle, all ligaments in both ankles torn and I know pain and can tolerate it, but this was way beyond normal.

Comment from: Wendy, 45-54 Female (Patient) Published: June 07

I had an endometrial biopsy today. While it is a quick procedure it felt as though the doctor unleashed the juggernaut in my uterus. I had the procedure done at 1:30 today. It's now 2:30 and I only have slight cramping.

Comment from: Ange, 45-54 Female (Patient) Published: June 06

When I read some of the comments on here prior to having my endometrial biopsy I was scared stiff so I'd like to share my more positive experience which shows that we don't all experience the same. Obviously we can't escape that fact that it's an embarrassing position to be in (excuse the pun). I can only describe the procedure as slightly uncomfortable. I experienced only spotting afterwards and no post procedure pain at all. If anyone needs to have this done it is necessary and not always painful. Good luck.

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Comment from: Mrs D., 55-64 Female (Patient) Published: June 06

The endometrial biopsy was ordered by my PCP (primary care physician) after I made a visit to her about seeing bright red blood. The medical staff at my gynecologist's office did not give me any details on what to expect. I was totally oblivious to the procedure. I have never felt any real pain until I had the procedure done. It only lasted about 2 minutes. Please ask questions before you make the visit. I was glad my coworker advised me to take a pain pill. However, I don't think it really helped at all.

Comment from: vlee, 45-54 Female (Patient) Published: June 02

I had an endometrial biopsy on 05/26 because of bleeding and spotting for 32 days. My gynecologist felt that it was due to perimenopause (I'm 48), but because it didn't follow the normal pattern, she ordered an ultrasound and biopsy. The ultrasound showed a slightly thickened and disorganized endometrium, so the biopsy was definitely warranted. Please, if you are told you need this done, do it. It wasn't something you would want every day but, at least with my experience, it wasn't that bad. Start to finish it took less than 5 minutes. It was like bad menstrual cramps and I cramped for about an hour after, just slightly. Slight/light bleeding after, but I was having that anyway. I got my results last night and thankfully, they were negative, but please, don't let fear keep you from doing a quick test that could potentially save your life!

Comment from: PJinNH, 55-64 Female (Patient) Published: June 01

Well, I had an endometrial biopsy done today. I took my Mobic this morning and 2 extra strength Tylenol (I really don't think it did any good at all). I'm a DES daughter and the doctor tried several times to get past the cervix and told me one more time and if that didn't work, I'd have to have the procedure done in the hospital. Last try he got in, but not without pinching me with the instruments (ouch). The cramping felt like someone grabbed the tissue down there with forceps, twisted around a dozen times and pulled and the actual removal of the tissue was worse. I was in tears and hoping all the time he could get the sample. He's pretty sure the test results will be benign and that my bleeding was due to a polyp. If I ever have to go through this again, I am going to ask for valium or something. It's ridiculous in this day and age you have to experience this amount of pain.

Comment from: h20tiger, 55-64 Female (Patient) Published: May 15

I just had endometrial biopsy today and I will admit I have a high pain threshold but I was definitely having a hard time keeping relaxed. I have never had children so nothing there to compare it to and I have a tilted cervix so that could have added to the discomfort. I do know that the 5 minutes of pain will be worth it to find out yay or nay. I basically told the doctor if it ends in an 'A' (hyperplasia, carcinoma or any other A) schedule the hysterectomy as soon as possible.

Comment from: earlymorning, 65-74 Female (Patient) Published: May 15

If endometrial biopsy were a procedure men had to undergo, I bet anesthesia would be standard procedure. I've had no pain since my endometrial biopsy. But the pain during the procedure took my breath away. I'd read the comments here beforehand, and had taken Tylenol (I have gastric problems with ibuprofen). Nonetheless, it was excruciating. I know that different women have different experiences with this; but many here seem to have a great deal of pain, as I did. (It didn't last long, but I'll not soon forget it.) I had a liver biopsy several years ago, and was given anesthesia, so no pain was involved. Isn't it time to address this!

Comment from: sunny, 55-64 Female (Patient) Published: May 11

Well, well, or maybe not so well, well; today was my turn to have an endometrial biopsy and after reading enough comments on this site to say that l was truly terrified. Having to wait 2 hours for my appointment did not help my nerves one bit. On being called in l burst into tears which is not like me, my general physician had told me to take pain killers 1 hour before which l had. The female doctor and nurse were lovely to me. I have quite a high pain threshold however out of 10 this was probably a 7 of discomfort. The instrument went through my cervix alright, l did feel it and it caused cramping. I certainly felt her scraping my womb with instrument. After taking it out l thought thank goodness but the doctor said he had to get some more cells to be sure, so round two started again. I gripped the nurse's hand very tight, and it was over. I was walking back to my car and l felt something trickling down my leg and thought l was bleeding, somehow l managed to get to my car. I could tell my pants were filling up with blood. Don't ask me how l got home but l did. I went straight to the bathroom to clean up, and yes, blood was running down my legs, I was scared, shaky and on my own. I was now crying in pain. I hadn't seen this much blood in 10 years. I took more pain medications and lay on the sofa with hot water bottle clutched to me and still bleeding. Now 5 hours later, still bad cramping and bleeding not quite so heavy. Verdict never again, if l ever have to have it again l will have a general anesthesia. I hope l stop bleeding soon and stop these cramps which are killing me now. I will update you all later with how my recovery is progressing. Good luck everyone who has this. I am trying to give you an honest overview. It would have helped if the doctor had told me this might happen.

Comment from: michelle, 45-54 Female (Patient) Published: May 02

I had my first endometrial biopsy due to some abnormal post-menopausal bleeding. I was prepared for severe pain because of things I have read and heard. I took the pain reliever an hour before the procedure. I did not feel any horrible pain like I thought I would. I felt slight cramping upon insertion of that tissue grabbing instrument, but that was it. Easy. The hardest part was for the poor gynecologist to find and see my cervix and that was probably due to my obesity.

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Comment from: Kathy, 65-74 Female (Patient) Published: May 01

April 26/17 I had an endometrial biopsy in the doctor's office due to one day of blood show 15 years after menopause. I have a huge pain tolerance generally, but I had no idea what this was and was not at all prepared. I was not told to take pain medicines ahead of time. For 15 minutes I stayed in stirrups while the doctor tried to dilate my cervix and then tried twice to get a sample with both metal and plastic instruments. I screamed and vomited from the pain. The doctor yelled at me for not 'helping the process' and I was sobbing when I left. I cannot believe this is not done under anesthetic in a hospital setting. I went home, took Tylenol and curled up in bed for hours rocking in pain. Never again.

Comment from: stargirl, 45-54 Female (Patient) Published: May 01

I had an endometrial biopsy done a few hours ago. It wasn't too bad. I pre-treated with one Tylenol (I can't take Advil due to a medical interaction) and this seemed to work some. I can't say it hurt all that badly, but it did feel uncomfortable because it is hard to source the exact place where it feels pinched inside. I had it done at 8:45 am, I was seated back at my desk working at 10:00 am. Minimal bleeding, some cramping after, but really not too bad. If you are searching the web for a bit of comfort regarding this procedure (as I was last night), I'm here to tell you it'll be ok.

Comment from: ninermom, 55-64 Female (Patient) Published: April 28

I had an endometrial biopsy done this afternoon because of some endometrial cells found in my Pap smear. It was the most painful experience of my life! I took Advil as instructed about an hour before the procedure was scheduled; as I was a work in, I did have it in my system for closer to 2 hours instead of one. I had forgotten how menstrual cramps felt, but this was like menstrual cramps on steroids! I hope I never have to go through this procedure again. Just waiting a couple of days to get the results, and hoping all is normal. I have slight cramping and some watery blood discharge, but nothing a panty liner cannot handle. I hope that will dispense within a day or so also as big plans for the weekend and vacation trip next week!

Comment from: Christina, 45-54 Female (Patient) Published: April 26

I am beyond angry at my doctor right now. And in general, and doctor who doesn't understand that endometrial biopsy might be painful for some, maybe most, if you read the comments here. Sadly, I did not read any of this before my procedure, if I had I would have at least asked for something. I've gone through IVF, so I've had some serious poking and prodding done, and have very painful menstrual cycles; this was the single most painful thing I've ever had done to me in a doctor's office.

Comment from: CALIGIRL, 35-44 Female (Patient) Published: April 14

I had an endometrial biopsy on Monday, and this was my 2nd time I had to experience this. This 2nd time was far the worst pain ever. I have never given birth so I don't know what that feeling is like but, oh my goodness, did I scream. Yes, it lasted for about 3 to 5 minutes, and I had 2 days of cramping. I am experiencing some light bleeding and discharge, but I can deal with that. All this to get ready for a hysterectomy.

Comment from: sdavis, 65-74 Female (Patient) Published: March 29

I had an endometrial biopsy today for a thickened lining. Having had a colposcopy some years back I was very nervous about having this procedure. I was given a pill to insert vaginally last night to soften the cervix and I took 2 Advil an hour before the procedure today. I have to say the anxiety was far worse than the procedure. There was a feeling of pressure but not really pain. It was over within a few minutes. On a scale of 1 to 10 I would say it was a 2 or 3.

Comment from: heatherjoy, 35-44 Female (Patient) Published: March 22

I have recently been scheduled for a hysterectomy due to fibroids. The obstetrician/gynecologist wanted to do an endometrial biopsy to make sure there was no cancer before proceeding. Got it. No problem. My cervix is so scarred, she had to dilate me, number one. Number two, that was the worst thing I have been through. Trying to have the Mirena IUD (intrauterine device) placed is a close second. I was so embarrassed. I have delivered twins and never acted like that. I felt dizzy and nauseous. I don't think there is any way to prepare for this.

Comment from: 45-54 Female (Patient) Published: March 06

I had endometrial biopsy yesterday, I cannot believe in this day and age we have to go through something so barbaric! The pain was excruciating! I'm so glad my friend was in there with me to hold my hand. The doctor had to clamp my cervix, then tried to get the instrument in, and it wouldn't go. So then she dilated me, then did the chopping; I was screaming. Then she decided to do another one just to make sure she had enough! When she said she was going to do the second one, I asked for something for the pain, and she said not necessary! I have had three kids, yes, that hurts, but at least you have drugs to help. I hope I never have to deal with that again!

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Comment from: nancyS, 55-64 Female (Patient) Published: March 06

I am 59 and have had postmenopausal bleeding off and on for 3 years. I had two other endometrial biopsies in the past. So I saw my gynecologist 3 weeks ago for the bleeding and he sent me for a transvaginal ultrasound and a pelvic ultrasound to determine how thick my uterine lining is. He said 5 or 6 cm is ok. Mine after the testing was found out to be 12 cm so that's why the endometrial biopsy today. I worried for 7 days, thinking of nothing else but the pain I experienced during the first 2, years ago with another gynecologist. So today I was pleasantly surprised how little it hurt. I took 3 Advil and felt just a mild cramping and it was over in about 4 minutes. He was gentle and now I just have light bleeding but no pain. He did say because I've had 2 children it might not hurt as much. Waiting 5 days for the results now. From reading all the reviews it seems like every woman is different with the pain.

Comment from: leelam, 45-54 Female (Patient) Published: February 22

I had an endometrial biopsy done two days ago and it was the worst pain I have ever felt. I have given birth twice so it's not like I don't have that as a baseline. The pain was something that filled the whole room and though it was short-lived it was the only thing I was aware of. My doctor told me I must have a high tolerance for pain as I didn't show any reaction to the pain, she was also really impressed with how well I did. All I was thinking as she said that was how much I wanted to punch her! She is amazing and very nice but that pain! I am still sore two days later. For those who had a pain free experience count yourself very lucky. I have to wait 2 weeks for my results, I wonder if there is any connection between having a problem like fibroids or polyps and the amount of pain.

Comment from: Bravegirl, 45-54 Female (Patient) Published: February 07

I had endometrial biopsy today. It was the most painful procedure I have ever endured. I wept. The consultant was so kind and after three attempts she managed to get enough for a biopsy which is very important. I was relieved.

Comment from: carlawilsons, 55-64 Female (Patient) Published: February 07

I am 59 years old. I have endometrial lining that is 11 mm. I have had light spotting twice a year for two years. A transvaginal sonogram says I have fibroids. I have been petrified to go for an endometrial biopsy because I read other postings saying that it is extremely painful. Well, today I had one done. The doctor used a Pipelle that had a plunger on the end which sucked up tissue. I am here to tell you that on a scale of 1 to 10 it was a 3! I had some cramping when he moved the Pipelle back and forth but that's it, no bleeding or after-cramps. The procedure was over in less than 7 minutes. Just a tip, take something for pain 1 hour before the procedure. Good luck!

Comment from: suefreedom, 45-54 Female (Patient) Published: February 02

I had an endometrial biopsy of my uterus done today in my gynecologist's office. It was impromptu and was probably the most painful procedure I have gone through. I was screaming and almost passed out twice. How is it that some people don't find this procedure painful!

Comment from: Shybutterfly, 45-54 Female (Patient) Published: January 24

I went for an endometrial biopsy on the 17th, it was performed in my doctor's office. My doctor tried several times to get the instrument in but it just would not go in so my doctor stopped and explained to me that she didn't want to force the instrument in and put me through that. She also explained that she will need my cervix to be dilated so she prescribed a medication for me to take an hour before my next visit which will be on the 30th. I am so glad that after trying several times she decided to stop whereas some doctors would have kept going and forcing the instrument into the cervix. This is the first time that I have ever had a biopsy done.

Comment from: Zeebee, 55-64 Female (Patient) Published: January 19

I had an endometrial biopsy today, no pain and no cramping. The procedure took about 5 minutes and I think that was because he couldn't get the first Pipelle in and had to dilate my cervix and use a smaller one. The only thing I felt was pressure. It was like an extended Pap for me. I am so sorry to hear of the horrible experiences others have had and am wondering if they are having different procedures. The Pipelle sucks up lining, no scraping, so maybe that is why it wasn't painful.

Comment from: Brandyelle, 35-44 Female (Patient) Published: January 19

I had an endometrial biopsy done yesterday. It was the fourth visit in less than two month to this obstetrician/gynecologist. I did not expect it to be painful during or after since I have a pretty high tolerance to pain although I did take the ibuprofen as suggested. She could not get into my uterus. The attempts were excruciating. She said that it was because my uterus is probably small and that she had never encountered this problem. I am rescheduled to go back on Wednesday. She prescribed me some medications to help dilate me. My concern is if I shouldn't have had a sonogram first due to the fact I have all the symptoms of fibroids. Seems to me that fibroids may be more reason for her not being able to get in than having a small uterus.

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Comment from: AK, 65-74 Female (Patient) Published: January 11

I have had two endometrial biopsies. The first one was 18 months ago, easy, very little pain. The second biopsy, done last Wednesday, hurt a lot. I think it is because I have a polyp and they needed to sample it. It turned out to be cancerous. I will need a hysterectomy. Six days later and I am in quite a bit of pain with cramping and soreness. I think I may have an infection because this got very painful at 5 in the morning. I took Percocet (oxycodone). By the way, you don't want to take aspirin or an NSAID like Advil because those can increase bleeding in surgery.

Comment from: Yogagirl24, 35-44 Female (Patient) Published: January 10

I had an endometrial biopsy done twice. They weren't pleasant, but they weren't terrible. The pain (pretty bad cramping) is felt during the procedure and for a minute or two afterwards. The procedure is fairly quick. Only thing is a couple of days later I experienced some clear gooey, yellowish discharge. I think it was an aftermath of the iodine used to prepare before the procedure.

Comment from: Boogie1953, 55-64 Female (Patient) Published: January 04

After experiencing some post-menopausal bleeding, I underwent a pelvic sonogram. The sonogram showed the endometrial lining was .7 which was of some concern to my obstetrician/gynecologist. I was scheduled for an endometrial biopsy so, of course, I went to this website to read some reviews and get an idea of what I might experience during this procedure. This site terrified me. I also had a friend who had told me this was the most painful experience she had ever had. I spent three weeks in utter dread of having this biopsy done. Let me put some of your minds to rest. It was a snap! The only difference from a normal Pap smear was that the instrument inserted through the cervix to actually snip the biopsy did cause a small amount of cramping that lasted all of two seconds. No extreme bleeding afterward and definitely no after affects that would cause great concern. Hope this makes some of you rest easier. Now the hard part is waiting for the results. Those of you scheduled for this procedure should maybe take a couple Advil beforehand and relax just as you would when undergoing a Pap. It is over so fast you hardly know it happened.

Comment from: Lee, 35-44 Female (Patient) Published: December 27

I had an endometrial biopsy (EB) done on Tuesday and I am still cramping and spotting/bleeding. I was not given any post procedure instructions. I feel like I may be starting my cycle. I don't know if this is part of the after effects of the EB. This was not a planned EB and was the most painful experience that I have ever had.

Comment from: Panapoo2002@gmail.co, 55-64 Female (Patient) Published: December 21

I had bleeding Tuesday after being in menopause for 8 years. I'm 56. I had endometrial biopsy Wednesday and fainted during the procedure which was beyond painful. I was told my cervix was like a nun's, never had a vaginal birth, and hard as cement. I'm now experiencing bloating, spotting, bursts of salmon colored fluid like your water breaking, and cramping. I am on day three following biopsy, still no results. I am taking ibuprofen for pain, and heating pad seems to help. Why in this day and age of technology this procedure is so archaic, and why you can't have twilight sleep and do it in a surgical center, I can't think. I would rather have a tooth pulled with no anesthetic then endure anything like this ever again!

Comment from: rachel45, 45-54 Female (Patient) Published: December 14

I had endometrial biopsy done today. Not fun. The pelvic ultrasound was a breeze but I experienced severe cramping during the biopsy. I believe an expletive may have been shouted out along with, ouch, ouch, ouch. Husband in waiting area heard me. But it was over fast and the cramping afterward was very minimal. I had slight bleeding for a few hours after. It was very painful for about 10 seconds and then done. Afterwards my doctor told me it was much easier to do in the office rather than put me under general anesthesia and have me spend the day in hospital. Uh. I wish I had been offered that as an option.

Comment from: Bri, 25-34 Female (Patient) Published: December 13

I had a uterine (endometrial) biopsy done about a month ago. I never had regular periods due to having PCOS (polycystic ovary syndrome) but never have had really any severe cramping, but with my period this month it feels like my uterus is being used as a trampoline while my ovaries are simultaneously being used as punching bags. I have done ibuprofen, and sitting in hot baths and heating pads. Sitting in the bath and the heating pad helps while I am doing but I can't live with the heating pad on me, or in the bathtub.

Comment from: DeborahBee, 35-44 Female (Patient) Published: December 05

I had an endometrial biopsy today, and was totally freaked out beforehand. It was not a big deal at all. In fact, I thought the doctor was still preparing me when she said she was all done! I did relax my lower jaw, a trick I learned in natural childbirth; your cervix has to relax when your mouth is relaxed. Honestly, getting my blood drawn from my arm later today hurt way worse than the biopsy. I am a little sore now that the ibuprofen has worn off, but not much. It was really not a big deal at all.

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Comment from: MaryN, 45-54 Female (Patient) Published: December 01

My doctor was having a hard time collecting tissue samples during my endometrial biopsy. So what I had expected to be a quick 1 minute procedure lasted much longer. It was very painful and I started sweating and getting nauseated. Only during the procedure, while trying to do small talk to distract me from the pain, the doctor found out that I had had an endometrial ablation 7 years ago, which explained why she was having difficulties extracting tissue samples; the lining was too thin. My concern now is if it was safe to undergo an endometrial biopsy after an endometrial ablation.

Comment from: NikkiBosler85, 25-34 Female (Patient) Published: November 23

I just had my first uterine biopsy today 11/21/16, or should I say, attempted. I have endometriosis and had a uterine ablation 2 years ago at age 29, and due to bleeding again my gynecologist wanted to do endometrial biopsy. I was not prepared. I have dealt with a lot of pain from surgeries, chronic illnesses, endometriosis, interstitial cystitis. This pain was excruciating. My doctor couldn't get past my cervix, so now I have to do it all over again in 2 weeks with medications to loosen my cervix and hopefully I can call and ask about a dose of Valium and pain medications. My tears were pooled under my head and I nearly passed out, that's when she decided to stop. She nicknamed my cervix 'Fort Knox'. Do yourself a favor, go to a happy place, breathe deep, take some pain medications, a squishy ball, and get it done if the doctor says you need it. But definitely take measures to not want to crawl up the wall to get away from the tommy knockers trying to eat your innards.

Comment from: Menopausal61, 55-64 Female (Patient) Published: November 17

I had an in-office endometrial biopsy done 48 hours ago due to postmenopausal spotting. It was the worst pain of my life. I was not told to take a pain reliever prior, but I can't imagine that it would have helped much unless it was prescription strength. I don't have a high tolerance to pain, but am not a wuss either. Shortly after the procedure I felt nauseated, light-headed and drenched in sweat. Fortunately I had someone to drive me home, because I couldn't have driven myself. What a brutal and archaic procedure! At the very least sedation should be used. The nausea and light-headedness continued until today. Now I await the biopsy results and hope it doesn't show endometrial cancer.

Comment from: Mrs. W, 55-64 Female (Patient) Published: November 15

I had an endometrial biopsy a year ago and again one today. Ouch! Ouch! I went home and took a Tylenol and then a nap, but when I awoke, ouch! Maybe it is my underlying condition that makes it hurt, but I am feeling tender. That said, I don't want to let a potential cancerous condition go unchecked. The results won't be back for a week or more.

Comment from: DJ, 55-64 Female (Patient) Published: November 15

The endometrial biopsy is terribly painful. Barbaric. I have had major surgeries, many procedures, etc., where sedation was used. I don't know why on earth sedation is not even offered. I would pay any amount not to go through that pain again. Tylenol! I don't think so!

Comment from: limitedgrace, 25-34 Female (Patient) Published: November 09

I had an endometrial biopsy or 'scratch' done as part of IVF treatment in September. I was advised to take 1000 mg ibuprofen 1 hour prior. It was the single most excruciating experience of my life! Directly beforehand my doctor advised that if I needed to scream that would be alright. I felt violated and traumatized by the experience and will not undergo it again without better pain management. For some of us this is a truly barbaric procedure.

Comment from: Denise, 45-54 Female (Patient) Published: November 01

I had an endometrial biopsy 10/25/16. There was no pain at all. Doctor told me to take two Advil before the procedure. I'm experiencing light spotting after the procedure for the past three days, however. I have a concern that blood appears to have been sitting in my uterus because that is what came out first. The instrument had to be reinserted to get a tissue sample. I've been in menopause since October 2014. Seems there should not have been any blood in the uterus at all. I'm now awaiting the results. Thanks!

Comment from: Serabi, 45-54 Female (Patient) Published: November 01

I found the endometrial biopsy pain to be unbearable, worse than labor. It appears that some women have no pain, and some of us have unbearable pain. I was not told to take so much as a Tylenol before the procedure, and was so traumatized I could barely drive myself home. It is not a matter of pain thresholds, as I have had migraines for 30 plus years and have learned to function even when the medications don't work; I have also had surgeries and extensive dental work without requiring pain killers afterwards. I suspect that there may be more nerves or different pathways, as there are in the mouth (when I get freezing I need it done in different spots than most). I am not trying to scare people, I just think we need to be prepared. If you haven't had one done yet, take some painkillers and arrange a drive just in case! If you are lucky it will be fine, if not you will not be surprised or trying to drive when unsafe.

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Comment from: Nomadona, 45-54 Female (Patient) Published: November 01

I had an endometrial Pipelle biopsy 5 days ago. This was an appointment and I was given no instructions. When the doctor came in, I was out ten minutes later. He described everything as he was doing it. I felt a little pressure when he opened my cervix and two sharp cramps for each of the samples he took. It was very much like menstrual cramps. I have 3 children so I don't know if that matters. I know a lot of women did not share which type of biopsy they had as I believe there are three. I am more concerned over the results. However, it has been 5 days and I am bleeding steadily. This was done half way after my cycle which you can set your watch to.

Comment from: donna, 55-64 Female (Patient) Published: October 31

I had my endometrial biopsy a day ago. I am not bleeding but having slight cramps. I was not told how painful this procedure would be, I was in so much pain during the procedure. The pain was worse than labor. It felt as if my intestines were going to explode and I nearly threw up. The doctor gave me an illustration of how far up my canal she had to go and spoke at each step. She said my reaction was same as all other patients who had the procedure. So why can't there be a better way to get this biopsy even in the office which is where mine was done! Now that I know how painful this procedure is, it will be hard for me to it again.

Comment from: Steelergirl, 45-54 Female (Patient) Published: October 24

All I can say is that this was the most awful pain that I experienced in a long time. I was not made aware that the endometrial biopsy would be so painful, this procedure should be done under sedation. I had my biopsy done on Wednesday and here it is Friday and I am still cramping and bleeding, never again!

Comment from: arizonamom, 45-54 Female (Patient) Published: October 20

I just had my obstetrician/gynecologist try to do an endometrial biopsy but I was in so much excruciating pain that she didn't do it. Now I am so angry that she told me to just take Tylenol before the appointment. I should have been sedated. I had extreme anxiety before and after and she told me to go walk the mall if I have anxiety, no medication needed. Never again! If I ever have to have this done I will get sedation or get my uterus taken out! I cannot believe that this is done without sedation.

Comment from: Charlie, 35-44 Female (Patient) Published: October 20

I had the endometrial biopsy today. I didn't know I was having one when I went in. Doctor said it would be painful but not even 40 seconds. Oh my goodness! It was horrible! I can take the pinch and whatever for 40 seconds but what I did not expect was the most horrible cramping! Oh, and a lot of blood! I'm still in pain hours later. I would have liked to know to take some sort of pain reliever prior!

Comment from: TMB, 35-44 Female (Patient) Published: October 19

I had the endometrial biopsy today. It was not as bad as I thought, and she had to do it twice. There was pain, but not horrible. I cramped a little afterwards but not bad. I did feel slightly lightheaded, maybe a little buzzed for a while after. I guess I found that odd. I will tell you that I did start my menstrual cycle this morning, and my doctor told me that would actually make it easier. Who would have thought! By the way, I did not take pain medications before or after.

Comment from: girlproblems, 45-54 Female (Patient) Published: October 17

I had an endometrial biopsy done yesterday. I was nervous because of reports I had read. Yes it hurt, but it really was not that bad. I did some deep breathing for the few seconds it took to get what they needed and it was over, 5 minutes tops. I had a small amount of bleeding and a few minutes of minor cramping, and that was it. So just relax, you will get through it, for me it really wasn't a big deal at all.

Comment from: Cookie, 45-54 Female (Patient) Published: October 10

I had a uterine biopsy done today. It was not that bad. I'm very happy to have the endometrial biopsy over with because the stress of needing it done was worse than the actual procedure. It didn't take very long at all. I'd say about three minutes start to finish.

Comment from: meme, 35-44 Female (Patient) Published: October 07

I just had endometrial biopsy done today, didn't know I was going to have it done so I didn't read anything ahead of time. I thought I was going in for a consultation for an endometrial ablation but apparently cancer has to be ruled out first so the biopsy was needed. It was really horrible, and I am used to having terrible cramps and heavy periods. First my doctor had trouble with my tight cervix and once she got in it only got worse. I could feel the blood running down me and when I sat up I was shocked how much was on the paper lining. Thankfully she had maxi pads available. It has now been 4 hours post procedure and I am still bleeding and cramping. I think this is one of those procedures that depends on the skill of the doctor preforming it and the condition of the recipient. I don't think taking pain medications would have helped, maybe sedation would have been better.

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Comment from: Faye, 65-74 Female (Patient) Published: October 07

Today I had my 2nd endometrial biopsy. My first one was at age 55. I am 67 now. The one at age 55 was somewhat painful, but this one was quite painful. Because of other tests going on, I was not able to take anything for pain before or after today's biopsy. I suggest anyone having this done to take a couple ibuprofen if you can. My doctor was very good about explaining everything he was about to do. I am super sensitive to touch sensation, so perhaps this caused me to feel the pain more. It only lasted a few minutes, but I felt dizzy and afterwards. I had nausea, then cramping.

Comment from: Dawn, 55-64 Female (Patient) Published: September 30

I had an endometrial biopsy today. I experienced extreme pain which I was not prepared for! My opinion, this procedure should be done while under sedation! I will be having a hysterectomy so I will not have to go through this again thank goodness!

Comment from: Aameee, 45-54 Female (Patient) Published: September 26

I had an endometrial biopsy procedure done and read about the horrible posts. Ladies, if you never had this procedure, please relax! I just had this procedure. About 30 years ago, I did have an abortion; now that was painful! I have suffered years of guilt, and mental pain about that story, but save that for another time. Anyway, I read the posts about this procedure and became terrified! I would advise taking some medicines; Motrin or ibuprofen. Talk to your doctor. I showed up weeping, my doctor reassured me and told me what he was doing step by step. You will feel a very slow dull pain when he inserts the suction. It felt like a squeeze but no bad pain, just a cramp. Count to 5 seconds, think of something else and that is all! Afterwards, you will feel like you are having regular period cramps, slight to regular bleeding, but don't worry, it is nothing! I feel a little foolish getting worked up about this.

Comment from: Jksmm3, 35-44 Female (Patient) Published: September 21

I just had the endometrial biopsy today. I made the mistake of reading this site first. My experience was nothing like what I read. It was nothing more than some small cramping, what I associate with a regular yearly check-up with my obstetrician/gynecologist. I fell sorry for all who had a bad experience.

Comment from: susdq1016, 55-64 Female (Patient) Published: September 15

I had endometrial biopsy this morning 9-14-16. I felt the anesthesia that went through my entire body and I felt drowsy at first, but they took only a 5 to 10 minutes for the procedure and then I was okay and back to normal. And I went back to work and felt fine.

Comment from: Mrs.G, 35-44 Female (Patient) Published: September 14

I am so sorry other women had painful experiences. I can say for myself that endometrial biopsy wasn't painful at all, it felt like a Pap smear procedure. Light cramping after procedure, but nothing unbearable.

Comment from: JA9, 45-54 Female (Patient) Published: September 07

I had an endometrial biopsy last week. I've read the range from no big deal to horrible. I thought I had a high pain tolerance but this was beyond anything I expected, I was already taking pain medicines for a hurt shoulder so I thought it would be fine. Seven years since menopause and bleeding, I was very nervous about the possibility of cancer. It was beyond painful; he had to dilate me just to get the sample, the scraping for the sample brought me off the table ready to pass out in tears.

Comment from: Em, 55-64 Female (Patient) Published: September 06

At the age of 62 I had an endometrial biopsy done yesterday after an ultra sound. I was not offered any pain relief and the pain was horrendous and it was done twice in succession. I was told it would be like period cramps, believe me it's a lot worse. Had I been informed previously that I was having this done I would have, as some have done, gone to see my general physician for pain relief before having this done.

Comment from: cindy1960, 55-64 Female (Patient) Published: September 06

I had an endometrial biopsy today and I am glad I didn't read this first! I barley felt when he went through my cervix and only had some cramping while the samples were taken. They were painful but not enough to make me cry out like some have said here. As soon as it was over, the cramps stopped. I have very light bleeding and was told I have no restrictions on my daily activity. I took two ibuprofen before my appointment. I was told I could bowl on my league tonight. I am sorry for those who have had a bad experience.

Comment from: SharJa, 55-64 Female (Patient) Published: August 16

I had a Pipelle endometrial biopsy this morning, after a fortnight of absolute dread after reading women's experiences of this procedure on this site. I took two tramadol painkillers an hour before my appointment. It obviously was not a pleasant experience but not horrendous either. I stayed calm and concentrated on my breathing. The cramping was like period pains but it only took around ten seconds to get the sample needed, then it was over. I had cramping pains for a few hours after, just like normal period pains, and some bleeding, but seriously, if you need this test done do not panic! It is an important test and over and done with so quickly. I am the biggest wimp going and if I can do this, anyone can!

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Comment from: Trina, 25-34 Female (Patient) Published: August 15

I had the uterine biopsy done after an ultrasound Tuesday to check the size of my fibroids and get a sample before having NovaSure done. I was scared to death when the doctor told me I had to have endometrial biopsy done because I had it 8 years ago and it was painful. I read some reviews and decided to call my doctor and ask for some medicine to help ease the pain of the procedure. She prescribed a Valium and 2 Percocet. I took that 40 minutes before the procedure and I didn't feel any pain. It was a breeze. The Valium calmed me down and I didn't tense up during the procedure. Now I'm just waiting on my results.

Comment from: td1960, 45-54 Female (Patient) Published: August 10

At 54 I had a period that started light, with light bleeding on and off for almost 21 days. My gynecologist told me I'd need a uterine biopsy, and told me this was done in office without anesthesia. I had never heard a patient describe an endometrial biopsy, just the doctor's description, so I looked up patient experiences. After seeing that some people had bad experiences, I changed gynecologists, since mine has dismissed my concerns about pain and she was rather rude and unpleasant. I found a better doctor affiliated with a major medical school hospital, and he did the biopsy under sedation/light anesthesia in the hospital's outpatient /same day surgery. I'd go and have this done again under anesthesia, it was not a bad experience. My gynecologist was the only doctor I have that is not affiliated with a teaching hospital, and her services were not as good. If looking to have this done in an emergency room, it can be done.

Comment from: KKrob, 45-54 Female (Patient) Published: August 02

I had the endometrial biopsy on Friday. The doctor was knowledgeable. I felt very confident with her. She did an ultrasound first and found two fibroids. But the biopsy was for polyps. She asked me if I wanted 2 shots to ease the pain. I opted out, because the pain of the needle might be worse. It went okay until the end. The instrument scraped my cervix on the way out and the bleeding didn't stop right away. She had to use spray and pressure for a long time to stop the bleeding. I felt crampy afterwards and was glad my daughter drove. I'm still spotting and crampy. No fever. I need to work Monday morning, but don't feel back to normal.

Comment from: Susie, 65-74 Female (Patient) Published: August 02

I had an endometrial biopsy done for the third time in my life. First time I was in my 30s. It was horrible. The second time I was in my 50s. It wasn't very bad but the third time I had it done, I am in my very early 70s. Never again! The doctor took way too long. She was conversing with the nurse while she was half way through, to boot. Seemed to take forever. I screamed and cried for 10 minutes. She had me as her last patient of the day so I guess she knew that this was going to happen and didn't inform me. Seems nothing has changed in over 40 years. We can put a man on the moon but medicine in some areas are archaic. I would never have it done again unless I am totally out. I even took a Vicodin before.

Comment from: birdy, 45-54 Female (Patient) Published: August 02

I had an endometrial biopsy yesterday and the doctor told me it was going to feel like cramps. Well, it felt more like labor pains! I did scream and I also cried but I knew it was a procedure that needed to be done to find out if I have cervical cancer. So I had to do what needed to be done to take care of my health.

Comment from: tre631981, 45-54 Female (Patient) Published: August 01

I had an endometrial biopsy two weeks ago. I had one done, unplanned, because of abnormal bleeding. My gynecologist told me everything that was going to happen while doing the procedure. I felt a little cramping. My experience wasn't bad at all. I bled for a few days and that was it.

Comment from: M, 55-64 Female (Patient) Published: July 28

I just had my first endometrial biopsy today. Felt mostly cramping, no pain and I do have some bleeding. My experience was not as bad as I thought it was going to be, my doctor was really great. Now I just wait for my results which I think will be the worst part of the whole thing.

Comment from: Deb, 45-54 Female (Patient) Published: July 27

I had an endometrial biopsy and a cervical polyp removal yesterday. I took 2 Advil and an Ativan to ease my stress. The whole procedure took 10 minutes, with 5 seconds of light cramping, and a little bleeding which has now stopped. Do not let people's scary negative experience scare and discourage you from having important tests. This was quick and really no big deal!

Comment from: Paula, 55-64 Female (Patient) Published: July 27

I am glad I did not see this blog before today. I would have been scared. As it was, I was unaware of what was to happen when I had my endometrial biopsy today. I too found it nearly unbearable. Yes, like a long ice pick being slowly pushed into a raw, open wound. I did succumb and let out a scream a moment before it was over, it was bad! Then I Immediately became light headed, nearly passed out and was actually slurring my words. Hey, we are women and we are tough old birds! If you have to go through this, go through it. It hurts, a lot, in a very weird, inside-out way. It is quick and once it is over it is over. I feel like it never happened. However, I don't think I could or would do it again without a Darvon or something.

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Comment from: Lynn, 55-64 Female (Patient) Published: July 22

I had the endometrial biopsy procedure done 4 days ago. I took medicine the night before and the morning of the procedure. They had trouble getting through the cervix. Cramping started but then when they were taking the samples it felt like a hot knife with a wire brush along with cramping. I could barely stand it and I have a high pain threshold. I broke out into a sweat, felt nauseous and weak. I lay for a while after and then sat outside for half an hour before I drove home. I had what appeared to be some clotting discharge and spotting. I still have spotting.

Comment from: katmando, 35-44 Female (Patient) Published: July 22

I just had an endometrial biopsy yesterday because my hemoglobin is 113 and my iron stores are at 10. Taking iron supplements and eating high iron foods is slowly helping but the doctor says I am just chasing the problem. Oh, and I am losing my hair because of it! Thank goodness I have lots to lose. I decided to take one 400 mg Advil (liquid-gels) an hour before. All went well, I had some cramping, as doctor had to take a few samples and some light bleeding. I felt pretty good for the remainder of the day until last night, I guess the Advil had run its course. Cramping was bad enough that it woke me up and I had shooting pains down my right leg and lower back, got chills, aches and pains all over. I got up for some more Advil and was able to rest after it started working again. Not feeling the best today, just generally feeling achy, little weak and some chills. I took another Advil, using a nice hot water bottle, sipping on some coffee and now feeling a little better. Hopefully tomorrow will be better. If it doesn't get any better in a few days, I will have to go back to the doctor to make sure there is no infection. I am waiting now for results, then booked for an intrauterine device, and if that doesn't work, then ablation it is. I am trying to avoid ablation if possible.

Comment from: sjde, 55-64 Female (Patient) Published: July 19

I have had 3 of these endometrial biopsies and they were awful. The first time I was told to take ibuprofen. I think I took 600 or 800 mg. It didn't seem to help so the 2nd time I took 5 mg Vicodin. That didn't seem to help much either so the 3rd time I took 1 1/2 oxycodone (7.5 mg) and still it was awful! I've had 2 natural childbirths.

Comment from: summer, 45-54 Female (Patient) Published: July 15

I had an endometrial biopsy due to the fact that I had 21 days of bleeding at 52. Only the last 6 days were heavy. Next period was fine. I missed the next one. Hormone test showed I am not in menopause. They did an internal ultrasound which showed uterine thickness. It was suggested that I get a biopsy, either in the office or a D and C in the hospital that I would be put out for. I was going to choose the D and C so I could be put under anesthesia because I read reviews that the regular biopsy was painful. This option ended up cost prohibitive. So I decided I'd have to do the office biopsy. I asked for something to help relax and for the pain. It was denied. I had read that it was painful and some women said barbaric. You always hope you are in the minority and that it won't be bad. I read that when they grasped the cervix it can cause cramping. I didn't have that; so far so good. Then they stuck in the mechanism to do the biopsy (a straw perhaps). I came up off of the table and let out a scream. The doctor asked me if I wanted to stop. After getting this far, I didn't want to not finish so I let her try again. I had my husband with me. I let out a scream again and clawed his hand and said some very bad profanities (which I usually never do). I forced myself to stay in position while I was cursing (the first attempt, I shot to the head of the table). This whole time I was muttering that it was ridiculous that in this day and age and medical knowledge that this had to be done under no pain medication. I don't want to scare anyone as they need to get something checked if it is for their health. But at the same time, I am glad I read the reviews as I can't imagine going through this if I thought it was no big deal. I am not sure how it is going to turn out but I won't do that again. It would have to be while I am under. The only positive I have is that I had only a trace amount of bleeding afterwards and no cramping. I felt tired but it was more like I was in a mental shock over the pain of it while it lasted.

Comment from: Notnormallyawimp, 55-64 Female (Patient) Published: June 28

I went in for my annual Pap smear test today and casually mentioned that I had a period after 8 months of none. I am 58. I have been thinking I was perimenopausal but after looking at my FSH (follicle stimulating hormone) my obstetrician/gynecologist said I was in menopause and wanted to see why I am still getting periods. The endometrial biopsy procedure was painful. I wish I could say otherwise. I knew nothing about it and said, sure just do it. She said there might be a little cramping. Oh my goodness, no. I kept asking when it was going to be over. I have a high pain threshold and have walked on nine broken bones in my foot before I knew they were broken. If I have to have this procedure again, I am going to ask for heavy painkillers. I am hoping I will feel better tomorrow.

Comment from: Linda, Female (Patient) Published: June 27

I had an endometrial biopsy today and was given a 2 mg Xanax and a 10 mg Valium 1 hour before procedure. The doctor was running behind and my sedation was wearing off. When she finally came in I was still a little relaxed. The pain was no more than heavy menstrual cramps and was over in 5 minutes. I took a Celebrex the night before and the morning of the procedure to help with pain. I really worried myself sick. Now I have to wait two weeks for results. I think this is the worst part.

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Comment from: HMK99, 35-44 Female (Patient) Published: June 15

I had an endometrial biopsy a week ago. I've never had children, and the doctor used a sound to widen/open my cervix so that she could insert the collection tube. The procedure was painful, like a hot knife stabbing my abdomen, both during the sounding and the two collection passes. I had abdominal pain and cramping for days. I also had some spotting/bleeding during the procedure, and I have continued to bleed since it was done, 7 days now. The procedure is not supposed to cause prolonged bleeding, yet many women report this very symptom post-uterine biopsy. It's clear to me that conventional/standard description of what to expect when you have a uterine biopsy is outdated and doesn't reflect the actual experiences of women receiving the procedure. I do not have the results of the biopsy yet, so I don't know if there are cancerous growths causing the bleeding. I'm scheduled for an ultrasound, but not for another month and a half.

Comment from: Susan, 65-74 Female (Patient) Published: June 14

I had a Pipelle endometrial biopsy 2 weeks ago. I did take pain killers 30 minutes before my appointment as suggested on my appointment letter. The doctor asked me to cough when he actually took the biopsy which took my mind off what he was doing. I felt really bad shooting pains but it was soon over. I also had cramps and bleeding for about a day after, plus feeling rubbish for a couple of days.

Comment from: Ori16, 35-44 Female (Patient) Published: June 01

I just had an endometrial biopsy yesterday at my doctor's office and I had a pretty bad reaction. There was awkward pain during the procedure, tugging and cramping. I can take a lot of pain though and it didn't take longer than maybe 15 or 20 minutes. In addition to the biopsy my doctor did a procedure to take pictures to see what if there was any damage in my uterus. They inserted an instrument to take pictures, with a light and inserted saline solution to get clear images. That all was more awkward feeling than the tugging of the biopsy. Afterward though it started with what was like a hot flash, then I had sweating, nausea, dizziness and an upset stomach and cramping. My blood pressure dropped very low. The nurse and doctor were very caring and gave me some peanut butter and crackers, water and eventually a shot of something for pain; I was out of it at that point. I lay there for half an hour then moved to another exam room to just lie there and rest until I could drive home. I lay there shivering so bad my teeth chattered for about 3 hours. Maybe if they told me to take pain medications before it would have been better. I don't know why I had that reaction. I did take 1 misoprostol the night before and 1 the morning of and that might have helped with not so much pain for the actual biopsy.

Comment from: Tink, 55-64 Female (Patient) Published: May 27

I had endometrial biopsy today with no preparation and it went fine. He told me it would hurt for about 10 seconds but it wasn't bad at all, just some pressure and slight pain. Now the wait for results.

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