- A Visual Guide to Migraine Headaches Slideshow
- Headache and Migraine Triggers Slideshow
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- What is eletriptan, and how does it work (mechanism of action)?
- What brand names are available for eletriptan?
- Do I need a prescription for eletriptan?
- What are the side effects of eletriptan?
- What is the dosage for eletriptan?
- Which drugs or supplements interact with eletriptan?
- Is eletriptan safe to take if I'm pregnant or breastfeeding?
- What else should I know about eletriptan?
What is eletriptan, and how does it work (mechanism of action)?
Eletriptan is an oral drug that is used for treating migraine headaches. It is in the "triptan" class of drugs that also includes sumatriptan (Imitrex), zolmitriptan (Zomig), naratriptan (Amerge), rizatriptan (Maxalt), almotriptan (Axert), and frovatriptan (Frova). Migraine headaches are believed to be the result of abnormal activity in the brain that leads to dilation of the blood vessels on the surface of the brain as well as the tissues that surround the brain. The dilation of the blood vessels is believed to be associated with inflammation. The triptan class of drugs, including eletriptan, constricts the blood vessels, thus preventing migraine headache. While it is very effective in relieving migraine, it does not prevent or reduce the number of attacks of migraine. In a large study, it was shown to be more effective than sumatriptan in relieving migraine headache pain within two hours. Eletriptan was approved by the FDA in December 2002.
What are the side effects of eletriptan?
Common side effects include:
- abdominal cramps, and
- chest pain,
- jaw pain, or
- neck pain.
More serious side effects include:
Quick GuideMigraine or Headache? Migraine Symptoms, Triggers, Treatment
What is the dosage for eletriptan?
Eletriptan 20 or 40 mg is taken at the first sign of a migraine attack. The maximum single dose is 40 mg. If the symptoms improve but then return after two hours or longer, a second tablet may be taken before calling the doctor. In any case, no more than 80 mg of eletriptan should be taken in any 24-hour period.
Which drugs or supplements interact with eletriptan?
Ergots, like dihydroergotamine (DHE 45) and ergotamine tartrate (Cafergot, Bellergal-S, Ergomar), or methysergide (Sansert) can causes constriction of blood vessels. It is possible that these effects may add to the effects of eletriptan. Therefore, it is recommended that ergot-containing drugs not be used within 24 hours of eletriptan.
Ketoconazole (Nizoral), itraconazole (Sporanox), nefazodone (Serzone), clarithromycin (Biaxin), ritonavir (Norvir), and nelfinavir (Viracept) may increase the amount of eletriptan in the blood by blocking an enzyme in the liver that's important in eliminating eletriptan. Eletriptan should not be taken if any of these medications have been taken within the previous 72 hours. Other drugs that block the same enzyme include diltiazem (Cardizem; Dilacor), Verapamil (Calan; Isoptin), fluconazole (Diflucan), voriconazole (VFend), indinavir (Crixivan), and erythromycin (Ery-Tab).
Is eletriptan safe to take if I'm pregnant or breastfeeding?
Safe use of eletriptan in pregnancy has not been established.
Safe use of eletriptan in nursing mothers has not been established.
What else should I know about eletriptan?
What preparations of eletriptan are available?
Tablets: 20 and 40 mg
How should I keep eletriptan stored?
Eletriptan should be stored at room temperature, 15 C - 30 C (59 F - 86 F), away from heat and light and out of the reach of children.
Eletriptan (Relpax) is a triptan drug that is prescribed to treat migraine headaches. Side effects, drug interactions, dosage, and pregnancy safety information should be reviewed prior to taking this medication.
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Top eletriptan Related Articles
HeadacheHeadaches can be divided into two categories: primary headaches and secondary headaches. Migraine headaches, tension headaches, and cluster headaches are considered primary headaches. Secondary headaches are caused by disease. Headache symptoms vary with the headache type. Over-the-counter pain relievers provide short-term relief for most headaches.
Migraine headaches are severe headaches that are sensitive to light, sounds, and smells. Some people who suffer from migraines also have severe head pain. People also have symptoms of nausea and vomiting. Common migraine triggers may include:
- Certain foods
- Changes in barometric pressure
- Other phenomenon
They are diagnosed by a doctor if the headache pattern fits established migraine headache criteria. Over-the-counter (OTC) and prescription medications are sometime used to treat acute migraines. To prevent or reduce the frequency and severity of them doctors recommend supplements and prescription medications, for example:
- Blood pressure drugs
- Anti-seizure drugs
Lifestyle modification helps in migraine management. Many people who suffer from migraines get relief from their condition by keeping a headache diary, identifying and avoiding triggers, and taking appropriate medication.
sumatriptanSumatriptan (Imitrex, Alsuma, Imitrex STATdose System, Sumavel DosePro) is in a class of drugs referred to as selective serotonin receptor agonists, and is prescribed for the treatment of migraine and cluster headaches. Side effects, warnings and precautions, and drug interaction information should be reviewed prior to taking this medication.
zolmitriptanZolmitriptan (Zomig, Zomig-ZMT) is a drug prescribed for the treatment of migraine headaches. Side effects, drug interactions, pregnancy information, dosing, and patient information should be reviewed prior to taking any medication.