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- What are PEG and electrolytes?
- What are examples of PEG and electrolytes available in the United States?
- What are the side effects of PEG and electrolytes?
- What drugs interact with PEG and electrolytes?
- What formulations of PEG and electrolytes are available?
- What about taking PEG and electrolytes during pregnancy or while breastfeeding?
What are PEG and electrolytes?
PEG and electrolytes are oral solutions used prior to colonoscopy and other examinations or procedures to cleanse the intestines, in particular, the large bowel or colon. The PEG remains in the intestines where it retains water by producing an osmotic effect. This causes a watery stool, in fact, diarrhea, which rapidly cleanses the bowel within hours. Polyethylene 3350 is used in all of the formulations. Since electrolytes (sodium, potassium, etc.) are lost with diarrhea, electrolytes are added to the PEG to replace or prevent the losses. The electrolytes and their concentrations may vary from product-to-product. PEG and electrolyte containing products are mixed with water and drunk for the cleanse.
What are examples of PEG and electrolytes available in the United States?
Examples of PEG and electrolytes brand names are:
- peg/electrolyte (Colyte)
- peg/electrolyte (Gavilyte-C)
- peg/electrolyte (Golytely)
- peg/electrolyte (Nulytely)
- polyethylene glycol 3350, sodium sulfate, sodium chloride, potassium chloride, sodium ascorbate, and ascorbic acid oral solution (Moviprep)
- peg-3350, sodium chloride, sodium bicarbonate and potassium chloride for oral solution (Trilyte)
What are the side effects of PEG and electrolytes?
Side effects of PEG and electrolytes are:
What drugs interact with PEG and electrolytes?
Oral medications administered within one hour of the start of PEG and electrolytes may be flushed from the body and may not be absorbed.
What formulations of PEG and electrolytes are available?
PEG and electrolytes are available as oral powder for solution.
- Colyte, Golytely, and Gavilyte contain polyethylene glycol 3350, sodium chloride, potassium chloride, sodium bicarbonate, and sodium sulfate.
- Moviprep contains polyethylene glycol 3350, sodium sulfate, sodium chloride, potassium chloride, sodium ascorbate and ascorbic acid.
- Nulytely contains polyethylene glycol 3350, sodium chloride, sodium bicarbonate and potassium chloride.
- Trilyte contains polyethylene glycol 3350, sodium chloride, sodium bicarbonate and potassium chloride.
- Colyte, Nulytely and Trilyte are available with flavor packs.
What about taking PEG and electrolytes during pregnancy or while breastfeeding?
The FDA classifies PEG and electrolytes as pregnancy category C, which means that there is no evidence of safe and effective use of PEG and electrolytes for pregnant women. PEG and electrolytes should be given to pregnant women only if clearly needed.
Latest Digestion News
Polyethylene glycol (PEG) and electrolytes are oral solutions prescribed to a patient by a health-care professional prior to colonoscopy and other examinations or procedures to cleanse the intestines, the colon (the large bowel) in particular. Side effects, drug interactions, brand names, formulations, and pregnancy and breastfeeding safety information should be reviewed prior to using this product.
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Related Disease Conditions
Stool Color, Changes in Color, Texture, and Form
Stool color changes can very from green, red, maroon, yellow, white, or black. Causes of changes of stool color can range from foods a person eats, medication, diseases or conditions, pregnancy, cancer, or tumors. Stool can also have texture changes such as greasy or floating stools. Stool that has a uncharacteristically foul odor may be caused by infections such as giardiasis or medical conditions.
Blood in the Stool (Rectal Bleeding, Hematochezia)
Blood in the stool or rectal bleeding (hematochezia) refers to the passage of bright red blood from the anus. Common causes include anal fissures, hemorrhoids, diverticulitis, colitis, Crohn's disease, colon and rectum polyps, and cancer. The color of the blood in the stool may provide information about the origin of the bleeding. The color of stool with blood in it may range from black, red, maroon, green yellow, gray, or white, and may be tarry, or sticky. Treatment of blood in the stool depends on the cause.
What Causes Abdominal Pain?
Abdominal pain can have many causes that range from mild to severe. Some of these causes include bloating, gas, colitis, endometriosis, food poisoning, GERD, IBS (irritable bowel syndrome), ovarian cysts, abdominal adhesions, diverticulitis, Crohn's disease, ulcerative colitis, gallbladder disease, liver disease, and cancers. Signs and symptoms of the more serious causes include dehydration, bloody or black tarry stools, severe abdominal pain, pain with no urination or painful urination. Treatment for abdominal pain depends upon the cause.
Colitis refers to inflammation of the inner lining of the colon. Symptoms of the inflammation of the colon lining include diarrhea, pain, and blood in the stool. There are several causes of colitis, including infection, ischemia of the colon, inflammatory bowel disease (Crohn's disease, ulcerative colitis, infectious colitis like C. difficile, or microscopic colitis). Treatment depends on the cause of the colitis.
Irritable Bowel Syndrome (IBS)
Irritable bowel syndrome (IBS) is a GI (gastrointestinal) disorder with signs and symptoms that include abdominal pain, bloating, increased gas (flatulence), abdominal cramping, diarrhea, constipation, and food intolerance.Two new tests are now available that may help diagnose irritable bowel syndrome with diarrhea and constipation (IBS-M) irritable bowel syndrome with diarrhea (IBS-D), and irritable bowel syndrome with constipation (IBS-C). Treatment for IBS includes diet changes, medications, and other lifestyle changes to manage symptoms.
Indigestion (Dyspepsia, Upset Stomach Pain)
Indigestion (dyspepsia) can be caused by diseases or conditions that involve the gastrointestinal (GI) tract, and also by some diseases and conditions that do not involve the GI tract. Indigestion can be a chronic condition in which the symptoms fluctuate in frequency and intensity. Signs and symptoms that accompany indigestion include pain in the chest, upper abdominal pain, belching, nausea, bloating, abdominal distention, feeling full after eating only a small portion of food, and rarely, vomiting.
Colon Polyps: Symptoms, Causes, Cancer Risk, Treatment, and Prevention
Colon polyps are common growths on the inner lining of the colon. Colon polyps may become cancerous. There are several different types of colon polyps, and the chance of the polyp becoming cancerous depends on the type, size, and histology. Blood in the stool or rectal bleeding are the most common symptoms of colon polyps. Treatment for colon polyps depend on the type, size, and histology.
Diverticulitis (Diverticulosis, Diverticular Disease)
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Inflammatory Bowel Disease (IBD)
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Melanosis coli is a condition that is often associated with prolonged laxative use. Dark pigment forms in the wall of the large intestine as a result of wear and tear. Melanosis coli (pseudomelanosis coli) causes no symptoms and can be reversed with discontinuation of laxative use.
Microscopic Colitis (Lymphocytic Colitis and Collagenous Colitis)
Microscopic colitis (lymphocytic colitis and collagenous colitis) is a disease of inflammation of the colon. Microscopic colitis is only visible when the colon's lining is examined under a microscope. The cause of microscopic colitis is not known. Symptoms of microscopic colitis are chronic watery diarrhea and abdominal pain or cramps.
Irritable Bowel Syndrome in Children (IBS)
Irritable bowel syndrome (IBS) in children is a functional gastrointestinal disorder with signs and symptoms of: Abdominal pain Bloating Diarrhea Constipation The cause of IBS is unknown, however, certain foods, stress, anxiety, and depression may contribute to the symptoms of IBS. There is no cure for IBS in children; however, medications, dietary changes, and stress management may relieve symptoms.
Colon Cancer Prevention
Colorectal cancer is both curable and preventable if it is detected early and completely removed before the cancerous cells metastasize to other parts of the body. Colonoscopy and flexible sigmoidoscopy (along with digital rectal examination and stool occult blood testing) are both effective at preventing colo-rectal cancers and detecting early colo-rectal cancers.
Disease Prevention in Women
Disease prevention in women includes screening tests that are a basic part of prevention medicine. All screening tests are commonly available through your general doctor. Some specialized tests may be available elsewhere.
Disease Prevention in Men
Disease prevention in men includes routine screening tests that are part of basic prevention medicine. Take an active role in your own health care and discuss screening tests with your doctor early in life. Age of screening and timing of screening depends upon the condition being assessed. Diseases men should take steps to prevent include high blood pressure (hypertension), hypercholesterolemia, type II diabetes mellitus, HIV (human immunodeficiency virus), colon cancer and colon polyps, prostate cancer, glaucoma, melanoma and other skin cancer, and bladder cancer.
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