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- What are PEG and electrolytes?
- What are examples of PEG and electrolytes available in the United States?
- What are the side effects of PEG and electrolytes?
- What drugs interact with PEG and electrolytes?
- What formulations of PEG and electrolytes are available?
- What about taking PEG and electrolytes during pregnancy or while breastfeeding?
What are PEG and electrolytes?
PEG and electrolytes are oral solutions used prior to colonoscopy and other examinations or procedures to cleanse the intestines, in particular, the large bowel or colon. The PEG remains in the intestines where it retains water by producing an osmotic effect. This causes a watery stool, in fact, diarrhea, which rapidly cleanses the bowel within hours. Polyethylene 3350 is used in all of the formulations. Since electrolytes (sodium, potassium, etc.) are lost with diarrhea, electrolytes are added to the PEG to replace or prevent the losses. The electrolytes and their concentrations may vary from product-to-product. PEG and electrolyte containing products are mixed with water and drunk for the cleanse.
What are examples of PEG and electrolytes available in the United States?
Examples of PEG and electrolytes brand names are:
- peg/electrolyte (Colyte)
- peg/electrolyte (Gavilyte-C)
- peg/electrolyte (Golytely)
- peg/electrolyte (Nulytely)
- polyethylene glycol 3350, sodium sulfate, sodium chloride, potassium chloride, sodium ascorbate, and ascorbic acid oral solution (Moviprep)
- peg-3350, sodium chloride, sodium bicarbonate and potassium chloride for oral solution (Trilyte)
What are the side effects of PEG and electrolytes?
Side effects of PEG and electrolytes are:
What drugs interact with PEG and electrolytes?
Oral medications administered within one hour of the start of PEG and electrolytes may be flushed from the body and may not be absorbed.
What formulations of PEG and electrolytes are available?
PEG and electrolytes are available as oral powder for solution.
- Colyte, Golytely, and Gavilyte contain polyethylene glycol 3350, sodium chloride, potassium chloride, sodium bicarbonate, and sodium sulfate.
- Moviprep contains polyethylene glycol 3350, sodium sulfate, sodium chloride, potassium chloride, sodium ascorbate and ascorbic acid.
- Nulytely contains polyethylene glycol 3350, sodium chloride, sodium bicarbonate and potassium chloride.
- Trilyte contains polyethylene glycol 3350, sodium chloride, sodium bicarbonate and potassium chloride.
- Colyte, Nulytely and Trilyte are available with flavor packs.
What about taking PEG and electrolytes during pregnancy or while breastfeeding?
The FDA classifies PEG and electrolytes as pregnancy category C, which means that there is no evidence of safe and effective use of PEG and electrolytes for pregnant women. PEG and electrolytes should be given to pregnant women only if clearly needed.
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Polyethylene glycol (PEG) and electrolytes are oral solutions prescribed to a patient by a health-care professional prior to colonoscopy and other examinations or procedures to cleanse the intestines, the colon (the large bowel) in particular. Side effects, drug interactions, brand names, formulations, and pregnancy and breastfeeding safety information should be reviewed prior to using this product.
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Stool Color, Changes in Color, Texture, and Form
Stool color changes can very from green, red, maroon, yellow, white, or black. Causes of changes of stool color can range from foods a person eats, medication, diseases or conditions, pregnancy, cancer, or tumors. Stool can also have texture changes such as greasy or floating stools. Stool that has a uncharacteristically foul odor may be caused by infections such as giardiasis or medical conditions.
Blood in the Stool (Rectal Bleeding, Hematochezia)
Blood in the stool or rectal bleeding (hematochezia) refers to the passage of bright red blood from the anus. Common causes include anal fissures, hemorrhoids, diverticulitis, colitis, Crohn's disease, colon and rectum polyps, and cancer. The color of the blood in the stool may provide information about the origin of the bleeding. The color of stool with blood in it may range from black, red, maroon, green yellow, gray, or white, and may be tarry, or sticky. Treatment of blood in the stool depends on the cause.
What Causes Abdominal Pain?
Abdominal pain can have many causes that range from mild to severe. Some of these causes include bloating, gas, colitis, endometriosis, food poisoning, GERD, IBS (irritable bowel syndrome), ovarian cysts, abdominal adhesions, diverticulitis, Crohn's disease, ulcerative colitis, gallbladder disease, liver disease, and cancers. Signs and symptoms of the more serious causes include dehydration, bloody or black tarry stools, severe abdominal pain, pain with no urination or painful urination. Treatment for abdominal pain depends upon the cause.
Colitis refers to inflammation of the inner lining of the colon. Symptoms of the inflammation of the colon lining include diarrhea, pain, and blood in the stool. There are several causes of colitis, including infection, ischemia of the colon, inflammatory bowel disease (Crohn's disease, ulcerative colitis, infectious colitis like C. difficile, or microscopic colitis). Treatment depends on the cause of the colitis.
Irritable Bowel Syndrome (IBS)
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Colon Polyps: Symptoms, Causes, Cancer Risk, Treatment, and Prevention
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Diverticulitis (Diverticulosis, Diverticular Disease)
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Colon Cancer Prevention
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Disease Prevention in Women
Disease prevention in women includes screening tests that are a basic part of prevention medicine. All screening tests are commonly available through your general doctor. Some specialized tests may be available elsewhere.
Disease Prevention in Men
Disease prevention in men includes routine screening tests that are part of basic prevention medicine. Take an active role in your own health care and discuss screening tests with your doctor early in life. Age of screening and timing of screening depends upon the condition being assessed. Diseases men should take steps to prevent include high blood pressure (hypertension), hypercholesterolemia, type II diabetes mellitus, HIV (human immunodeficiency virus), colon cancer and colon polyps, prostate cancer, glaucoma, melanoma and other skin cancer, and bladder cancer.
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