Ehlers-Danlos Syndromes: Symptoms & Signs

Ehlers-Danlos syndromes are a group of inherited disorders that share common symptoms such as easy bruising, joint hypermobility (loose joints), skin that stretches easily (skin hyperelasticity or laxity), and weakness of tissues. These defects cause the body to produce abnormal forms of the protein collagen that plays a role in maintaining many body tissues.

Ehlers-Danlos syndrome symptoms and signs can include

Other common symptoms and signs can include

  • joint dislocations,
  • scoliosis,
  • instability of joints that causes frequent strains and sprains,
  • sagging skin,
  • muscle shrinking, and
  • fragile skin that takes on a smooth, velvety appearance.

Cause of Ehlers-Danlos syndromes

Inherited genetic changes (mutations) that pass from parents to offspring cause Ehlers-Danlos syndromes.

Other ehlers-danlos syndromes

  • Being Double Jointed
  • Bleeding
  • Elastic Skin
  • Fragile Skin With a Smooth, Velvety Appearance
  • Heart Murmur
  • Joint Dislocations
  • Joint Instability Leading to Sprains and Strains
  • Joint Pain
  • Muscle Pain
  • Muscle Shrinking
  • Muscle Weakness
  • Physical Deformity
  • Poor Wound Healing
  • Sagging Skin
  • Scoliosis
  • Wrinkles

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Medically Reviewed on 9/29/2019
References
Kasper, D.L., et al., eds. Harrison's Principles of Internal Medicine, 19th Ed. United States: McGraw-Hill Education, 2015.