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- What is efinaconazole Jublia, and how does it work (mechanism of action)?
- What are the side effects of efinaconazole Jublia?
- What is the dosage for efinaconazole Jublia?
- Which drugs or supplements interact with efinaconazole Jublia?
- Is efinaconazole Jublia safe to take if I'm pregnant or breastfeeding?
- What else should I know about efinaconazole Jublia?
What is efinaconazole Jublia, and how does it work (mechanism of action)?
Efinaconazole is a topical (applied to the skin) antifungal used for the local treatment of fungal infections of the toenails. Efinaconazole destroys fungal cells by inhibiting fungal lanosterol 14α-demethylase, an enzyme required to make ergosterol, an important fungal cell wall component. Without cell walls fungus cannot survive. Efinaconazole was approved by the FDA in June, 2014.
What brand names are available for efinaconazole Jublia?
Is efinaconazole Jublia available as a generic drug?
Do I need a prescription for efinaconazole Jublia?
What are the side effects of efinaconazole Jublia?
: The most common side effects of treatment are mainly irritation of the area(s) efinaconazole is applied to. Side effects include:
What is the dosage for efinaconazole Jublia?
: Efinaconazole is applied to the affected toenail(s) once daily for 48 weeks. When applying efinaconazole, patients should make sure that the toenails, toenail beds, and surrounding skin are completely covered. For best results, apply efinaconazole to dry toenails. Patients should wait for at least 10 minutes after showering, bathing, or washing before applying efinaconazole. Patients should avoid pedicures, use of nail polish, or cosmetic nail products while using efinaconazole. Efinaconazole is only intended for use on toenails and surrounding skin.
The safety and effectiveness of efinaconazole has not been established in pediatric patients.
Which drugs or supplements interact with efinaconazole Jublia?
: No known drug interaction has been identified with efinaconazole.
Is efinaconazole Jublia safe to take if I'm pregnant or breastfeeding?
NURSING MOTHERS: It is not known if efinaconazole is excreted in breast milk. As many drugs are excreted in human milk and have the potential of harming the nursing infant, efinaconazole should be used cautiously in nursing mothers.
What else should I know about efinaconazole Jublia?
What preparations of efinaconazole Jublia are available?
PREPARATIONS: Topical solution: 10%
How should I keep efinaconazole Jublia stored?
STORAGE: Efinaconazole should be stored at room temperature, from 15 C to 30 C (59 C to 86 F). Efinaconazole is flammable and should be protected from heat or flames. Efinaconazole containers should be stored in an upright position. Keep efinaconazole and all medications out of the reach of children.
Latest Skin News
Efinaconazole (Jublia) is an antifungal cream applied to the toenails and surrounding skin to treat toenail fungus. Side effects, drug interactions, and pregnancy safety information should be reviewed prior to taking any medication.
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Related Disease Conditions
Fungal nails (onychomycosis) may be caused by many species of fungi, but the most common is Trichophyton rubrum. Distal subungal onychomycosis starts as a discolored area at the nail's corner and slowly spread toward the cuticle. In proximal subungal onychomycosis, the infection starts at the cuticle and spreads toward the nail tip. Yeast onychomycosis is caused by Candida and may be the most common cause of fungal fingernail.
Athlete's foot (tinea pedis) is a skin infection caused by the ringworm fungus. Symptoms include itching, burning, cracking, peeling, and bleeding feet. Treatment involves keeping the feet dry and clean, wearing shoes that can breathe, and using medicated powders to keep your feet dry.
Ingrown Toenail (Onychocryptosis)
Ingrown toenails are caused by the growth of the toenail into the surrounding nail fold. Symptoms and signs include toe pain, swelling, redness, and yellow drainage. Treatment at home involves soaking the affected foot in diluted white vinegar or Epsom salts, elevating the foot, and trimming the nails straight across. Surgery is also an option for severe cases. Prevent ingrown toenails by wearing shoes with a wider toe box and avoiding repeated injury to the toenails. Avoid curving or cutting the nails short at the edges.
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Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.