- Enlarged Prostate (BPH) Pictures Slideshow
- Prostate Cancer Slideshow Pictures
- Take the Enlarged Prostate Quiz!
- What is dutaseride? How does it work (mechanism of action)?
- What are the uses for dutasteride?
- What are the side effects of dutasteride?
- What is the dosage for dutasteride?
- Which drugs or supplements interact with dutasteride?
- Is dutasteride safe to take if I'm pregnant or breastfeeding?
- What else should I know about dutasteride?
What is dutaseride? How does it work (mechanism of action)?
Dutasteride is a medication used for the treatment of benign prostatic hyperplasia (BPH) also known as an enlarged prostate. Dutasteride belongs to a class of medication called 5-alpa reductase inhibitors. Male hormone dihydrotestosterone (DHT) is primarily responsible for development and enlargement of the prostate gland. Testosterone is converted into DHT by 5-alpha reductase enzyme. Dutasteride blocks 5-alpha reductase enzyme and prevents excessive DHT production in the prostate gland. This delays the progression of an enlarged prostate and improves symptoms of BPH.
The FDA approved dutasteride in November 2001.
What are the uses for dutasteride?
What are the side effects of dutasteride?
Dutasteride causes many sexual side effects.
Common side effects are:
Allergic reaction such as swelling under the skin may occur. Dutasteride also increases risk of high-grade prostate cancer. Patients must contact their healthcare professional if unusual reactions to dutasteride occur.
What is the dosage for dutasteride?
The recommended dose of dutasteride is 0.5 mg once daily. Do not chew the medication and do not administer to pediatric patients.
Which drugs or supplements interact with dutasteride?
Medications such as ketoconazole (Nizoral), cimetidine (Tagamet), diltiazem (Cardizem), verapamil (Calan), ritonavir (Norvir) and clarithromycin (Biaxin) slow down the breakdown of dutasteride. This may lead to increased levels of dutasteride in the body, increasing side effects such as decreased libido, erectile dysfunction, and impotence.
Medications such as carbamazepine (Tegretol) and primidone (Mysoline) increase the breakdown of dutasteride in the body. This may lead to decreased levels of dutasteride in the body, lowering the beneficial effects of the medication.
Is dutasteride safe to take if I'm pregnant or breastfeeding?
It is not known whether dutasteride enters breast milk.
What else should I know about dutasteride?
What preparations of dutasteride are available?
Dutasteride is available as 0.5 mg liquid-filled capsules.
How should I keep dutasteride stored?
Dutasteride capsules should be stored between 15 C to 30 C (59 F to 86 F).
Dutasteride is available in generic form, but must be prescribed by a doctor or other health-care professional. The brand name available for dutaseride is Avodart.
Multimedia: Slideshows, Images & Quizzes
Benign Prostatic Hyperplasia (Enlarged Prostate) Quiz
Take the Enlarge Prostate Quiz and challenge your knowledge of prostate problems. Learn causes, symptoms, treatments, and...
Enlarged Prostate (BPH) Symptoms, Diagnosis, Treatment
Benign Prostatic Hyperplasia (BPH) is a condition cause by an enlarged prostate. Get more information on how an enlarged prostate...
Picture of Prostate Gland
A gland within the male reproductive system that is located just below the bladder. See a picture of Prostate Gland and learn...
Picture of Prostate
Side View of the Prostate. The prostate is a walnut-sized gland located between the bladder and the penis. See a picture of the...
Related Disease Conditions
There are many causes of scalp hair loss. This featured article covers the common ones such as patchy hair loss (alopecia areata,...
Prostatitis (Inflammation of the Prostate Gland)
Prostatitis is an inflammation of the prostate gland. Signs and symptoms of prostatitis include painful or difficulty urinating,...
Enlarged Prostate (BPH, Benign Prostatic Hyperplasia)
Benign prostatic hyperplasia (BPH or enlarged prostate) is very common in men over 50 years of age. Half of all men over the...
Men's Health: Keys to a Healthy Life
Second Source article from Government...
Men's health is an important component to a happy lifestyle and healthy relationships. Eating healthy, exercise, managing stress,...
There are many types of urinary incontinence (UI), which is the accidental leakage of urine. These types include stress...
Treatment & Diagnosis
Medications & Supplements
Prevention & Wellness
Health Solutions From Our Sponsors
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.