Drug-Induced Liver Disease: Symptoms & Signs

Medically Reviewed on 1/29/2021

Drug-induced liver disease is a disease of the liver.

Mild drug injury to the liver may not produce any symptoms. Signs and symptoms of drug-induced liver disease, when they do appear, vary in severity and can include

Causes of drug-induced liver disease

Physician-prescribed medications, over-the-counter medications, illicit drugs, environmental toxins, or other substances such as supplements, hormones, or vitamins may cause drug-induced liver disease. Many drugs can cause liver diseases. Examples include chemotherapy drugs and drugs used to treat hypertension, high cholesterol, diabetes, and irregular heart rhythms.

Other drug-induced liver disease symptoms and signs

Jameson, J. Larry, et al. Harrison's Principles of Internal Medicine, 20th Ed. New York: McGraw-Hill Education, 2018.