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- Do I need a prescription for doxycycline?
- What is doxycycline?
- What brand names are available for doxycycline?
- Is doxycycline available as a generic drug?
- Why is doxycycline prescribed to patients?
- What are the side effects of doxycycline?
- What is the dosage for doxycycline?
- Which drugs or supplements interact with doxycycline?
- Is doxycycline safe to use during pregnancy or while breastfeeding?
- What else should I know about doxycycline?
What is doxycycline?
Doxycycline is a synthetic (man-made) antibiotic derived from tetracycline.
What brand names are available for doxycycline?
Brand names for doxycycline hyclate include Vibramycin, Oracea, Adoxa, Atridox, Acticlate, Acticlate Cap, Doryx, Doxteric, Doxy, Monodox, and others.
Why is doxycycline prescribed to patients?
Doxycycline is used for many different types of infections, including respiratory tract infections due to Hemophilus influenzae, Streptococcus pneumoniae, or Mycoplasma pneumoniae. It also is used for the treatment of
What are the side effects of doxycycline?
Doxycycline is generally well-tolerated. The most common side effects are
Tetracyclines, such as doxycycline, may cause tooth discoloration if used in persons below 8 years of age. Exaggerated sunburn can occur with tetracyclines; therefore, sunlight should be minimized during treatment.
What is the dosage for doxycycline?
- The absorption of doxycycline is not markedly affected by food, and therefore, it can be taken with meals.
- For most infections, doxycycline is taken once or twice daily for 7 to 14 days.
- For adult infections, the usual dose of oral doxycycline is 200 mg on the first day of treatment (100 mg every 12 hours) followed by a dose of 100 to 200 mg/day as a single dose or divided and administered twice daily.
Which drugs or supplements interact with doxycycline?
- It is recommended that doxycycline not be taken at the same time as aluminum, magnesium, or calcium based antacids, such as Mylanta, Maalox, Tums, or Rolaids because, like food, these medications bind doxycycline in the intestine and prevent its absorption. Similarly, doxycycline should not be taken with minerals (such as calcium or iron) or with bismuth subsalicylate (Pepto Bismol).
- Doxycycline may enhance the activity of warfarin (Jantoven, Coumadin) and cause excessive "thinning" of the blood leading to exaggerated bleeding, necessitating a reduction in the dose of warfarin. Phenytoin (Dilantin), carbamazepine (Tegretol), and barbiturates (such as phenobarbital) may enhance the metabolism (destruction) of doxycycline thus making it less effective.
- Doxycycline may interfere with the action of penicillins and should not be combined with penicillins. It may also reduce the effect of oral contraceptives. Combining tetracycline and methoxyflurane (Penthrane) may reduce kidney function.
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Is doxycycline safe to use during pregnancy or while breastfeeding?
- Tetracycline antibiotics, such as doxycycline, can have toxic effects on development of bone in the fetus. Therefore, tetracyclines are not recommended during pregnancy unless there is no other appropriate antibiotic.
- Doxycycline is secreted into breast milk but the extent of absorption by the breastfed infant is not known. Since tetracyclines can cause toxic effects on bone, the use of tetracyclines in nursing mothers is of concern. The physician must decide whether to recommend that a nursing mother discontinue nursing during treatment with tetracyclines or change to a different antibiotic.
What else should I know about doxycycline?
What preparations of doxycycline are available?
- Capsules: 50, 75, 100 and 150 mg.
- Capsule (Delayed Release): 40 mg.
- Tablets: 20, 50, 75, 100 and 150 mg.
- Tablets (Delayed Release): 50, 60, 75, 80, 100, 120, 150, and 200 mg.
- Syrup: 50 mg/5 ml (teaspoon)
- Oral Suspension: 25 mg/5ml
- Powder for injection: 100and 200 mg.
- Periodontal Extended Release Liquid: 10%
How should I keep doxycycline stored?
- Tablets, capsules, and syrup should be kept at room temperature 15 C to 30 C (59 F to 86 F) in tight, light resistant containers.
- Powder for injection should be stored at or below 25 C (77 F) and protected from light.
- Atridox (doxycycline in a gel used for subgingival application) should be stored at 2 C to 8 C (36 F to 46 F).
How does doxycycline work?
- Doxycycline works by interrupting the production of proteins by bacteria. It is effective against a wide variety of bacteria, such as Hemophilus influenzae, Streptococcus pneumoniae, Mycoplasma pneumoniae, Chlamydia psittaci, Chlamydia trachomatis, Neisseria gonorrhoea, and many others.
When was doxycycline approved by the FDA?
The FDA approved doxycycline in December 1967.
Doxycycline (Vibramycin, Oracea, Adoxa, Atridox, Acticlate, Acticlate Cap, Doryx, Doxteric, Doxy, Monodox, and others) is a synthetic broad-spectrum antibiotic derived from tetracycline. It is used to treat many different types of infections, including respiratory tract infections due to Hemophilus influenzae, Streptococcus pneumoniae, or Mycoplasma pneumoniae. It also is used for the treatment of
- nongonococcal urethritis (due to Ureaplasma),
- Rocky mountain spotted fever,
- syphilis, and
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Related Disease Conditions
Acne is a localized skin inflammation as a result of overactivity of oil glands at the base of hair follicles. This inflammation, depending on its location, can take the form of a superficial pustule (contains pus), a pimple, a deeper cyst, congested pores, whiteheads, or blackheads. Treatments vary depending on the severity of the acne.
Diverticulitis (Diverticulosis, Diverticular Disease)
Most people with diverticulosis have few if any symptoms at all. When people do experience signs and symptoms of diverticulosis (diverticular disease) they may include abdominal pain, abdominal cramps, diarrhea, constipation, and bloating. Diverticulitis is a condition in which diverticuli in the colon rupture. The rupture results in infection in the tissues that surround the colon. Treatment methods for diverticulitis includes prescription medications, and in some cases, diverticulitis surgery.
Leptospirosis is an infectious disease that causes symptoms such as fever, headache, and chills. Treatment for leptospirosis requires antibiotics.
Lyme disease is a bacterial illness, which is spread by ticks when they bite the skin. Initially the disease affects the skin causing a reddish rash associated with flu-like symptoms. It takes weeks to months after the initial redness of the skin for its effects to spread throughout the body. Lyme disease can be treated with antibiotics. Lyme disease can be prevented by using tick avoidance techniques.
Malaria is a disease that is spread by the bite of an infected Anopheles mosquito. Malaria symptoms include fever, chills, nausea, vomiting, and body aches. Treatment involves supportive care and antibiotics.
Melioidosis (Whitmore's disease) is an infectious disease caused by Burkholderia pseudomallei bacteria. Symptoms include bronchitis, pneumonia, fever, headache, loss of appetite, cough, and chest pain. Treatment involves antibiotics or surgical removal of the lung abscess in severe cases.
Osteoarthritis is a type of arthritis caused by inflammation, breakdown, and eventual loss of cartilage in the joints. Also known as degenerative arthritis, osteoarthritis can be caused by aging, heredity, and injury from trauma or disease.
Rosacea is a skin disease that causes redness of the forehead, chin, and lower half of the nose. In addition to inflammation of the facial skin, symptoms include dilation of the blood vessels and pimples (acne rosacea) in the middle third of the face. Oral and topical antibiotics are treatments for rosacea. If left untreated, rhinophyma (a disfiguring nose condition) may result.
Sexually Transmitted Diseases in Women (STDs)
Sexually transmitted diseases (STDs) are among the most common infectious diseases in the United States. STDs can be spread through any type of sexual activity involving the sex organs, the anus or mouth, or through contact with blood during sexual activity. Examples of STDs include, chancroid, chlamydia, gonorrhea, granuloma inguinale, lymphogranuloma venereum, syphilis, genital herpes, genital warts, trichomoniasis, pubic lice (crabs), and scabies. Treatment is generally with antibiotics; however, some STDs that go untreated can lead to death.
Travelers should prepare for their trip by visiting their physician to get the proper vaccinations and obtain the necessary medication if they have a medical condition or chronic disease. Diseases that travelers may pick up from contaminated water or food, insect or animal bites, or from other people include: malaria, meningococcal meningitis, yellow fever, hepatitis A, typhoid fever, polio, and cholera.
Urinary Tract Infection (UTI)
A urinary tract infection (UTI) is an infection of the bladder, kidneys, ureters, or urethra. E. coli, a type of bacteria that lives in the bowel and near the anus, causes most UTIs. UTI symptoms include pain, abdominal pain, mild fever, urinary urgency and frequency. Treatment involves a course of antibiotics.
Anthrax is a deadly infectious disease that may be transmitted to humans by infected animals or by biological warfare. There are three types of anthrax: cutaneous, inhalation, and gastrointestinal. Symptoms of cutaneous anthrax include a swollen glands, muscle ache, headache, fever, nausea, vomiting, and a red-brown raised spot that enlarges, blisters, and hardens, forming an ulcer crater with black crust. Symptoms of inhalation anthrax are flu-like and may progress to respiratory distress, shock, coma, and death. Symptoms of gastrointestinal anthrax include loss of appetite, bloody diarrhea, and abdominal pain. Treatment for cutaneous anthrax involves penicillin, tetracycline, erythromycin, and ciprofloxin. Inhalation anthrax necessitates treatment with IV therapy with antibiotics.
Chlamydia in Women
Chlamydia is the most common sexually transmitted disease in the U.S. Signs and symptoms of chlamydia, a bacterial infection, include vaginal discharge, abdominal pain, burning with urination, blood in the urine, and feelings of urinary urgency and frequency. Untreated chlamydia can cause pelvic inflammatory disease (PID), increased risk of ectopic pregnancy, and infertility. Chlamydia is diagnosed with a culture or by identification of the genetic material of the bacteria. Treatment of chlamydia consists of a course of antibiotics.
Yaws is an infectious disease that mainly occurs in the tropical areas of South and Central America, Asia, Africa, and the Pacific Islands. The disease is caused by a bacterium called Treponema pertenue, which causes lesions that look like bumps on the skin of the feet, hands, face, and genital area. Yaws is treated with penicillin or another antibiotic.
Travelers' diarrhea is generally contracted by eating contaminated food or drinking contaminated water. Food is the primary source of travelers' diarrhea. Enterotoxigenic E. coli is the cause of up to 70% of all cases of travelers' diarrhea. There are five unique classes of E. coli that causes gastroenteritis. Other bacteria responsible for travelers' diarrhea include Campylobacter, jejuni, shigella, and salmonella. Viruses such as rotavirus and Norwalk virus (norovirus) and giardia lamblia a parasite may cause travelers' diarrhea. Prevention is careful eating and drinking of water.
Pregnancy and Drugs (Prescription and OTC)
Taking prescription medications or over-the-counter drugs or supplements should be discussed with your doctor. There are some medications that have been found to cause no problems in pregnancy, however, medications such as Accutane for acne, should never be taken during pregnancy.
Heart Attack Prevention
Heart disease and heart attacks can be prevented by leading a healthy lifestyle with diet, exercise, and stress management. Symptoms of heart attack in men and women include chest discomfort and pain in the shoulder, neck, jaw, stomach, or back. Women experience the same symptoms as men; however, they also may experience: Extreme fatigue Pain in the upper abdomen Dizziness Fainting Leading a healthy lifestyle with a heart healthy low-fat diet, and exercise can help prevent heart disease and heart attack.
Legionellosis is an infection caused by the Legionella pneumophila bacterium. There are two forms of legionellosis: Pontiac fever and Legionnaires' disease, which is the more severe of the two infections. Symptoms of Pontiac fever include fever, headache, muscle aches, and chills. Symptoms of Legionnaires' disease include cough, chills, fever and sometimes muscle aches, headaches, loss of appetite, diarrhea, and severe pneumonia. While Pontiac fever resolves on its own, Legionnaires' disease must be treated with antibiotics.
STDs in Men
Sexually transmitted diseases (STDs) are infections transmitted during sexual contact. They may be caused by viruses, bacteria, or parasites. STDs in men cause no symptoms or symptoms like genital burning, itching, sores, rashes, or discharge. Common infections that are sexually transmitted in men include gonorrhea, chlamydia, syphilis, hepatitis C and B, genital warts, human papillomavirus (HPV), and genital herpes. Some STDs in men are treatable while others are not. STDs are diagnosed with tests that identify proteins or genetic material of the organisms causing the infection. The prognosis of an STD depends on whether the infection is treatable or not. Use of latex condoms can help reduce the risk of contracting an STD but it does not eliminate the risk entirely.
Cholera is an infectious disease characterized by intense vomiting and profuse watery diarrhea and that rapidly lease to dehydration and often death. Cholera is caused by infection with the bacteria Vibrio cholerae, which may be transmitted via infected fecal matter, food, or water.
Dry eyes are caused by an imbalance in the tear-flow system of the eye, but also can be caused by the drying out of the tear film. This can be due to dry air created by air conditioning, heat, or other environmental conditions. Treatment may involve self-care measures, medications, or rarely, surgery.
Sty (Definition, Causes, Pictures, and Treatment)
A sty is a bump that forms on the eyelid as a result of a blocked gland. Styes may be caused by infections, burns, or trauma to the eyelid. Most styes resolve on their own. The application of warm compresses can speed healing. In some cases, steroid injection or incision and drainage may be necessary. Keeping the area clean and consuming a diet high in omega-3-fatty acids may help prevent the formation of styes.
MRSA (methicillin-resistant Staphylococcus aureus) bacteria causes skin infections with the following signs and symptoms: cellulitis, abscesses, carbuncles, impetigo, styes, and boils. Normal skin tissue doesn't usually allow MRSA infection to develop. Individuals with depressed immune systems and people with cuts, abrasions, or chronic skin disease are more susceptible to MRSA infection.
Rocky Mountain Spotted Fever (RMSF)
Rocky Mountain spotted fever is a tick-borne disease that causes symptoms and signs such as fever, rash, headache, and muscle aches. The antibiotic doxycycline is the standard treatment for Rocky Mountain spotted fever.
Bug Bites and Stings
Bug bites and stings have been known to transmit insect-borne illnesses such as West Nile virus, Rocky Mountain spotted fever, and Lyme disease. Though most reactions to insect bites and stings are mild, some reactions may be life-threatening. Preventing bug bites and stings with insect repellant, wearing the proper protective attire, and not wearing heavily scented perfumes when in grassy, wooded, and brushy areas is key.
Jock itch is an itchy red rash that appears in the groin area. The rash may be caused by a bacterial or fungal infection. People with diabetes and those who are obese are more susceptible to developing jock itch. Antifungal shampoos, creams, and pills may be needed to treat fungal jock itch. Bacterial jock itch may be treated with antibacterial soaps and topical and oral antibiotics.
Blepharitis is inflammation of the eyelids. Acne rosacea, staphylococcal bacteria, allergies, sensitivities to makeup or contact lens solutions, head lice, or other conditions may cause blepharitis. Symptoms and signs include itchy eyelids, burning sensation in the eyes, crusting of the eyelids, light sensitivity, red, swollen eyelids, loss of eyelashes, and dandruff of the lashes and eyebrows. Proper eyelid hygiene and a regular cleaning routine controls blepharitis.
The bacteria Brucella causes brucellosis, an infectious zoonotic disease in humans. Symptoms and signs include fatigue, fever, sweating, and appetite loss. The preferred treatment is doxycycline and rifampin taken for six to eight weeks.
Tularemia (rabbit fever) is an infection caused by the Francisella tularensis bacteria. People can become infected with tularemia by coming into contact with infected animals or via a tick bite. Symptoms and signs include fever, headache and rash. Tularemia is treated with streptomycin or gentamicin.
Typhus is a disease caused by Rickettsia bacteria. Symptoms and signs include fever, headache, nausea, vomiting, diarrhea, and rash. Antibiotics are recommended as the treatment for endemic and epidemic typhus infections.
Onchocerciasis, or river blindness, is a parasitic disease that may cause blindness. It is transmitted by the bite of a female blackfly. Symptoms include skin depigmentation, vision loss, and itch. Ivermectin is used to treat the disease.
Q fever is a highly infectious disease that causes high fever, diarrhea, cough, and sweating. Infected animals may transmit Q fever to humans. Antibiotics are available to treat Q fever.
Is Chlamydia Contagious?
Chlamydia is a sexually transmitted disease (STD) that is contagious. Chlaymida is spread through sexual contact. (You cannot get chlamyidia from kissing or sharing utensils or drinks.) Chlamydia is the most common STD in the U.S. The incubation period for chlamydia ranges from days to months, and the contagious period ends seven days after patients begin treatment. Chlamydia signs and symptoms may include painful urination, rectal irritation (proctitis), eye infections, and infertility. Women can also develop chronic pelvic pain, salpingitis, and endometritis.
Cystic acne is distinguised by painful nodules on the chest, face, neck, and back. This form of acne is known to scar. Treatment may incorporate the use of hormonal therapies, oral antibiotics, and prescription medications.
Pimple vs. Cold Sore
Pimples are areas of skin inflammation with pus in the center. Cold sores are fluid-filled blisters. Pimples are caused by bacterial overgrowth and inflammation. Cold sores are caused by infection with herpes simplex viruses (HSV-1 and HSV-2). Benzoyl peroxide and sometimes antibiotics treat acne. Antiviral medications accelerate the healing process of oral herpes.
Prostatitis vs. BPH (Enlarged Prostate) Differences and Similarities
Prostatitis and BPH (benign prostatic hyperplasia, enlarged prostate gland) are both conditions of the prostate gland. There are four types of prostatitis that can be caused by infections (usually bacterial) or other health conditions or problems, acute bacterial prostatitis (type I), chronic bacterial prostatitis (type II), chronic prostatitis and chronic pelvic pain syndrome (type III), and asymptomatic inflammatory prostatitis (type IV). BPH is inflammation of the prostate gland, and most men have the condition by age 50. Doctor's don't know what causes this inflammation, but they theorize that it may be related to hormones. Both of these conditions can cause similar symptoms like low back pain, pain during urination, or difficulty or the inability to urinate. However, prostatitis has many more symptoms and signs than BPH, and they based on the type of prostatitis. Examples include low back pain and/or abdominal pain, painful urination, fever, chills, feeling tired, recurrent urinary tract infections (UTIs), painful urination intermittently, intermittent obstruction urinary tract symptoms (frequent, painful, or incomplete urination), pelvic pain and/or discomfort, pain with ejaculation, and erectile dysfunction (ED). If you think you have either of these conditions contact your doctor or other health care professional. Bacterial prostatitis can be cured with antibiotics; however, there is no cure for BPH.
Treatment & Diagnosis
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