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- What is docusate-oral, and how does it work (mechanism of action)?
- What are the side effects of docusate-oral?
- What is the dosage for docusate-oral?
- Which drugs or supplements interact with docusate-oral?
- Is docusate-oral safe to take if I'm pregnant or breastfeeding?
- What else should I know about docusate-oral?
What is docusate-oral, and how does it work (mechanism of action)?
Docusate is a commonly used non-prescription (OTC or over-the-counter) stool softener used to treat or prevent constipation. Docusate is an anionic surfactant that helps lower the surface tension at the oil-water interface of the stool, and thus allows water and lipids or fats to enter the stool. Consequently, fecal matter is softened which helps natural defecation or bowel movement. Relief of constipation may occur with 1 to 3 days of therapy. Docusate is available in various salt forms including docusate sodium, docusate potassium, and docusate calcium. The salt forms of docusate are considered to be interchangeable. Docusate was approved by the US Food and Drug Administration (FDA) in 1957.
What brand names are available for docusate-oral?
Aqualax, Colace, Colace Micro-Enema, Conate, Correctol Extra Gentle, Diocto, DocQLace, Docu Soft, Docu, Docuprene, Docusil, DocuSol Kids, DocuSol Mini, DOK, Dulcolax Stool Softener, D.O.S., DC Softgels, Dialose, Enemeez Mini, Genasoft, GoodSense Stool Softener, Fam-Colsof, Healthy Mama Move It Along, Kao-Tin, KS Stool Softener, Laxa Basic, Modane Soft, Phillips Liquid-Gels, Pedia-Lax, Promolaxin, Regulax SS, Silace, Sof-Lax, Stool Softener Laxative DC, Stool Softener, Sulfolax, Surfak, Sur-Q-Lax, Therevac SB, Top Care Stool Softener, Uni-Ease, Vacuant Mini-Enema, Vacuant Plus
Is docusate-oral available as a generic drug?
GENERIC AVAILABLE: Yes
Do I need a prescription for docusate-oral?
What are the side effects of docusate-oral?
Docusate salts rarely cause side effects since they are not absorbed into the body. Occasional side effects may include
Throat irritation has occurred in some patients after taking liquid formulations of docusate orally.
Excessive use of docusate may cause low electrolyte levels and may also result in dependence. Docusate should not be used in people with
What is the dosage for docusate-oral?
- Adult (≥ 12 years): The recommended oral dose is 50 to 500 mg/day in 1 to 4 divided doses. The recommended rectal dose is 50 to100 mg of docusate liquid added to enema fluid.
- Pediatric: The recommended dose for infants and children <3 years is 10 to 40 mg/day in 1 to 4 divided doses. The recommended dose in children between the ages of 3 to 6 is 20 to 60 mg/day in 1 to 4 divided doses. The recommended dose in children between the ages of 6 to 12 is 40-150 mg/day in 1 to 4 divided doses.
Which drugs or supplements interact with docusate-oral?
No significant drug to drug interactions have been reported with docusate salts. Administration of docusate with mineral oil is not recommended because docusate may increase the absorption of mineral oil which may lead to serious allergic reactions.
Is docusate-oral safe to take if I'm pregnant or breastfeeding?
Docusate is generally considered to be safe during breastfeeding.
What else should I know about docusate-oral?
What preparations of docusate-oral are available?
- Docusate Calcium: Softgel Capsules: 240 mg
- Docusate Sodium: 100 mg capsules; 100 mg liquid filled capsules; 50 mg/5 ml oral solution; 50 mg/5 ml oral suspension; 60 mg/15 ml syrup; 100 mg tablets; 100 mg rectal enema suspension; 282 mg rectal enema suspension.
How should I keep docusate-oral stored?
Tablets should be stored at room temperature between 15 C to 30 C (59 F to 86 F).
Latest Digestion News
Daily Health News
Docusate (Aqualax, Colace, Colace Micro-Enema, Conate, Correctol Extra Gentle, Diocto, DocQLace, Docu Soft, Docu, Docuprene, Docusil, DocuSol Kids, DocuSol Mini, DOK, Dulcolax Stool Softener, D.O.S., DC Softgels, Dialose, Enemeez Mini, Genasoft, GoodSense Stool Softener, Fam-Colsof, Healthy Mama Move It Along, Kao-Tin, KS Stool Softener, Laxa Basic, Modane Soft, Phillips Liquid-Gels, Pedia-Lax, Promolaxin, Regulax SS, Silace, Sof-Lax, Stool Softener Laxative DC, Stool Softener, Sulfolax, Surfak, Sur-Q-Lax, Therevac SB, Top Care Stool Softener, Uni-Ease, Vacuant Mini-Enema, Vacuant Plus) is a common OTC stool softener used to treat and prevent constipaiton. Side effects, drug interactions, dosage, storage, and pregnancy safety information should be reviewed prior to taking this medication.
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Laxatives for Constipation
Laxatives types for treatment of constipation include over-the-counter (OTC) preparations, for example, bulk-forming laxatives, stool softeners, lubricant laxatives, stimulant or saline laxatives, enemas, and suppositories. Some OTC laxatives are not recommended for people with specific diseases or conditions (for example, people with diabetes). Some laxatives may have negative side effects if taken over a long time. Laxatives are not recommended for weight loss.
Diverticulitis (Diverticulosis, Diverticular Disease)
Most people with diverticulosis have few if any symptoms at all. When people do experience signs and symptoms of diverticulosis (diverticular disease) they may include abdominal pain, abdominal cramps, diarrhea, constipation, and bloating. Diverticulitis is a condition in which diverticuli in the colon rupture. The rupture results in infection in the tissues that surround the colon. Treatment methods for diverticulitis includes prescription medications, and in some cases, diverticulitis surgery.
Irritable Bowel Syndrome (IBS)
Irritable bowel syndrome (IBS) is a GI (gastrointestinal) disorder with signs and symptoms that include abdominal pain, bloating, increased gas (flatulence), abdominal cramping, diarrhea, constipation, and food intolerance.Two new tests are now available that may help diagnose irritable bowel syndrome with diarrhea and constipation (IBS-M) irritable bowel syndrome with diarrhea (IBS-D), and irritable bowel syndrome with constipation (IBS-C). Treatment for IBS includes diet changes, medications, and other lifestyle changes to manage symptoms.
Constipation (Relief, Home Remedies, Treatment Medications)
Constipation is defined medically as fewer than three stools per week and severe constipation as less than one stool per week. Constipation usually is caused by the slow movement of stool through the colon. There are many causes of constipation including medications, poor bowel habits, low fiber diets, laxative abuse, and hormonal disorders, and diseases primarily of other parts of the body that also affect the colon.
IBS Triggers (Prevention)
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Is Diverticulitis Contagious?
Diverticulitis is an inflammation of the diverticula or diverticulum. Diverticulitis causes are either infectious or noninfectious, however, it is not contagoius. Symptoms of diverticulitis include: nausea, vomiting, diarrhea, gas, constipation, changes in bowel habits, bloating, constipation, fever, abdominal tenderness, swollen abdomen, fistula formation, and lower left abdominal pain.
Pregnancy Changes and Body Discomforts
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Treatment & Diagnosis
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Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.