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- Is dobutamine-injection available as a generic drug?
- Do I need a prescription for dobutamine-injection?
- What are the uses for dobutamine-injection?
- What are the side effects of dobutamine-injection?
- What is the dosage for dobutamine-injection?
- Which drugs or supplements interact with dobutamine-injection?
- Is dobutamine-injection safe to take if I'm pregnant or breastfeeding?
- What else should I know about dobutamine-injection?
What are the uses for dobutamine-injection?
- Dobutamine is prescribed to help increase cardiac output in a failing heart due to heart disease or cardiac surgery.
What are the side effects of dobutamine-injection?
The most frequent adverse reactions include
- increased heart rate,
- increased blood pressure,
- irregular ventricular beats, and
- chest pain.
Other important side effects include
Serious side effects of dobutamine include
- abnormal heart beats,
- increased heart rate,
- low blood pressure,
- chest pain,
- fainting , and
- eosinophilic myocarditis.
Quick GuideHeart Disease: Symptoms, Signs, and Causes
What is the dosage for dobutamine-injection?
- The initial dose for adults is based on the indication and severity of heart failure.
- Dosing is 0.5 to 1 micrograms per kilogram body weight per minute followed by an intravenous infusion of 2 to 20 micrograms per kilogram body weight per minute.
- Maximum dose is 40 micrograms per kilogram per minute.
Which drugs or supplements interact with dobutamine-injection?
- Use caution when combining dobutamine with other agents that increase heart rate or blood pressure (sympathomimetics), such as atomoxetine (Strattera), dopamine, and epinephrine.
- Use lower doses of dobutamine initially if the patient is also on linezolid (Zyvox) as there is a risk of significant increase in blood pressure.
- Calcium salts may decrease the effect of dobutamine, so monitor closely.
Is dobutamine-injection safe to take if I'm pregnant or breastfeeding?
What else should I know about dobutamine-injection?
What preparations of dobutamine-injection are available?
Intravenous solution: 250, 500, 1000 mg in 250 mL, 250 mg in 20 mL, 500 mg in 40 mL
How should I keep dobutamine-injection stored?
- Vials should be stored at room temperature, between 15 C to 30 C (59 F to 86 F).
- Once diluted, dobutamine may be stored in the refrigerator (4 C) for 7 days or up to 48 hours at room temperature.
REFERENCE: FDA Prescribing Information.
Dobutamine injection (Dobutrex brand has been discontinued in the US) is a prescription drug in the drug class of catecholamines. Dobutamine is prescribed to assist with cardiac output in a person with a failing heart due to heart disease or cardiac surgery. Side effects and frequent adverse reactions include:
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