Ask the experts

Do diuretics decrease the effectiveness of Vicodin?

Doctor's response

There should not be any interaction between diuretics and hydrocodone/acetaminophen (Vicodin). If the Vicodin is not working, you should look to other causes than the diuretic.

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References

Medically reviewed by John A. Daller, MD; American Board of Surgery with subspecialty certification in surgical critical care

REFERENCE:

"Cancer pain management: Use of acetaminophen and nonsteroidal antiinflammatory drugs"
UpToDate.com

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Do Diuretics Interact with Vicodin?

Ask the experts

Doctor's response

Related Article

Pain Management: Surprising Causes of Pain