What is Diprolene (betamethasone dipropionate)?

Diprolene Lotion (betamethasone dipropionate) is a corticosteroid topical medication used to relieve itching and inflammation associated with a wide variety of skin conditions in patients 13 years of age or older. Examples include allergic dermatitis, atopic dermatitis, contact dermatitis, and plaque psoriasis

Common side effects of Diprolene Lotion include:

  • burning at the area of application,
  • itching,
  • irritation, and
  • dryness.

Serious side effects of Diprolene Lotion include:

  • severe skin irritation where the medicine was applied, and
  • signs of skin infection (swelling, redness, warmth, oozing).

Drug interactions of Diprolene Lotion include topical anthralin, which may increase psoriasis symptoms

Use of Diprolene Lotion in pregnant women has not been studied. When corticosteroids are given systemically (orally, intramuscularly, or intravenously) to pregnant animals, fetal abnormalities occur. 

It is unknown if Diprolene Lotion is secreted in breast milk. Corticosteroids absorbed into the body may appear in breast milk and may cause harmful effects in breastfed infants. Consult your doctor before breastfeeding.

What are the important side effects of Diprolene Lotion (betamethasone dipropionate)?

The most common side effects of betamethasone are:

  • burning at the area of application,
  • itching,
  • irritation, and
  • dryness.

Diprolene Lotion (betamethasone dipropionate) side effects list for healthcare professionals

Clinical Trials Experience

Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in clinical practice.

In controlled clinical trials, adverse reactions associated with the use of Diprolene Lotion reported at a frequency of less than 1% included erythema, folliculitis, pruritus, and vesiculation.

Postmarketing Experience

Because adverse reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure.

Postmarketing reports for local adverse reactions to topical corticosteroids may also include: skin atrophy, striae, telangiectasias, burning, irritation, dryness, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, secondary infection, hypertrichosis, and miliaria.

Hypersensitivity reactions, consisting of predominantly skin signs and symptoms, e.g., contact dermatitis, pruritus, bullous dermatitis, and erythematous rash have been reported.

What drugs interact with Diprolene Lotion (betamethasone dipropionate)?

No information provided.

Summary

Diprolene Lotion (betamethasone dipropionate) is a corticosteroid topical medication used to relieve itching and inflammation associated with a wide variety of skin conditions in patients 13 years of age or older. Examples include allergic dermatitis, atopic dermatitis, contact dermatitis, and plaque psoriasis. Common side effects of Diprolene Lotion include burning at the area of application, itching, irritation, and dryness. Drug interactions of Diprolene Lotion include topical anthralin, which may increase psoriasis symptoms. Use of Diprolene Lotion in pregnant women has not been studied. It is unknown if Diprolene Lotion is secreted in breast milk.

Treatment & Diagnosis

Medications & Supplements

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Medically Reviewed on 4/10/2020
References
FDA Prescribing Information
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