GENERIC NAME: DIPHTHERIA/TETANUS/ACELLULAR PERTUSSIS (ADULT) - INJECTION (dip-THEER-ee-uh/TET-un-us/per-TUSS-iss)
USES: This medication is given to maintain protection (immunity) against diphtheria, tetanus (lockjaw), and pertussis (whooping cough) in children and adults aged 11 to 64 years who have been vaccinated for these diseases in the past.Vaccination is the best way to protect against these life-threatening diseases. Vaccines work by causing the body to produce its own protection (antibodies). Booster doses are needed to maintain immunity because antibody levels may become too low over time to provide the needed protection.
HOW TO USE: Read the Vaccine Information Statement available from your health care provider before receiving the vaccine. If you have any questions, consult your health care provider.This vaccination should be given at least 5 years since your last vaccination for diphtheria, tetanus, or pertussis. Tell your doctor about all the vaccinations you have received.Shake the medication well before using. This medication is given by injection into a muscle by a health care professional. It is usually given in the upper arm. Do not inject into a vein or into the skin.Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid. Discard any unused vaccine remaining in the vial or syringe.If you are receiving other vaccines (e.g., hepatitis B) at the same time, they should be injected into a different site with a separate syringe.
SIDE EFFECTS: Headache, tiredness, body aches, nausea, diarrhea, fever, chills, vomiting, pain/swelling/redness at the injection site, or sore/swollen joints may occur. Acetaminophen or ibuprofen may be used to reduce soreness. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.Tell your doctor immediately if any of these rare but very serious side effects occur: difficulty breathing, high fever (higher than 104 degrees F/40 degrees C), numbness/tingling, muscle weakness, inability to move (paralysis).A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.Contact your doctor for medical advice about side effects. The following numbers do not provide medical advice, but in the US, you may report side effects to the Vaccine Adverse Event Reporting System (VAERS) at 1-800-822-7967. In Canada, you may report side effects to Health Canada at 1-866-234-2345.
PRECAUTIONS: Before receiving this vaccination, tell your doctor or pharmacist if you are allergic to it; or to any other vaccines; or to latex; or if you have any other allergies.This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: uncontrolled seizures or other nervous system disorder (e.g., encephalopathy), history of severe reaction to vaccine (e.g., paralysis, encephalopathy).Before using this medication, tell your doctor or pharmacist your medical history, especially of: bleeding disorders (e.g., hemophilia, low platelets), history of Guillain-Barre syndrome, immune system disorders (e.g., autoimmune disorders, radiation treatment), current illness/infection, seizures (e.g., epilepsy controlled by medication, febrile seizures), other nervous system disorders (e.g., paralysis, numbness/tingling, severe drowsiness, confusion), previous reactions to any vaccine (e.g., high fever, seizures).During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.It is not known whether this drug passes into breast milk. Consult your doctor before breast-feeding.
DRUG INTERACTIONS: Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.Before receiving this vaccine, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: "blood thinners" (e.g., warfarin), corticosteroids (e.g., hydrocortisone, prednisone), cancer chemotherapy, drugs that weaken the immune system (e.g., cyclosporine, tacrolimus), other recent/planned vaccines (e.g., diphtheria/tetanus toxoids).This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.
OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US National Poison Hotline at 1-800-222-1222. Canada residents can call a provincial poison control center.
NOTES: There are various combinations of vaccines available. Based on your age, vaccination history, and previous reaction to vaccines, your health care professional will determine the most appropriate one for you. Discuss the risks and benefits of vaccination with your health care professional.History of infection with tetanus or diphtheria does not always protect against future infections with these bacteria. You should still receive this vaccine if your doctor orders it for you.
MISSED DOSE: It is important to receive each vaccination as scheduled. Be sure to make a note of when the vaccination was last given for your medical record.
STORAGE: Refrigerate between 36-46 degrees F (2-8 degrees C). Do not freeze. Discard this product if it has been frozen. Keep all medicines away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.
Adult tetanus, diphtheria, pertussis (Td, Tdap) vaccine is an injectable drug used to maintain immunity against diphtheria, lock jaw (tetanus), and whooping cough (pertussis) in children and adults.
Side effects of the Tdap vaccine include redness, warmth, and pain, swelling around the injection site, drowsiness, and rash. More serious side effects include, vomiting, fretfulness, collapse, convulsions, and crying for more than three hours. Dosage and safety during pregnancy and breastfeeding information are provided.
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Related Disease Conditions
Shingles (Herpes Zoster)
Shingles, or herpes zoster, is a painful rash caused by the varicella zoster virus. Other shingles symptoms include headache, fever, nausea, and body aches. Treatment focuses on pain management and shortening the duration of the illness with antiviral medications.
Is Shingles Contagious?
Shingles is an infection caused by the varicella-zoster virus. Shingles symptoms and signs include skin burning, numbness, and tingling along with a painful red, blistering rash. Shingles is contagious until all of the blisters have crusted over.
Tetanus is an often-fatal disease caused by nerve toxins produced by the common bacteria Clostridium tetani. In a 7-day period after infection, a person experiences muscle spasms, restlessness, headache, irritability, then lockjaw, and the lungs stop functioning. Tetanus is treatable with antibiotics and drainage. Sedation is often give to stop muscle spasms.
Is Scarlet Fever Contagious?
Scarlet fever is contagious when caused by a certain Group A strep bacteria strain. Scarlet fever can be transmitted via person-to-person contact and by coming in contact with contaminated objects. Treatment includes antibiotics. Scarlet fever symptoms include a red rash, fever, a red, sore throat, strawberry tongue, and others.
Whooping Cough (Pertussis)
Whooping cough (pertussis) is a highly contagious respiratory infection caused by the bacteria Bordetella pertussis. There are an estimated 300,000 plus deaths annually from whooping cough (pertussis). Whooping cough commonly affects infants and young children but can be prevented with immunization with the vaccine. First stage whooping cough symptoms are a runny nose, sneezing, low-grade fever, a mild cough with the cough gradually becoming more severe. After one to two weeks, the second stage of whooping cough begins.
Yellow fever is an infectious disease transmitted by infected mosquitoes. Side effects are rare with the yellow fever vaccine. Symptoms include fever, chills, back pain, nausea, vomiting, and headache. Treatment is aimed at relieving symptoms.
What Happens When You Get Shingles When Pregnant?
Becoming infected with chickenpox during pregnancy could cause birth defects in your unborn child. Likewise, shingles could also cause problems for your unborn child. If you are pregnant and haven't had chickenpox, avoid exposure to infected people. Zostavax, the shingles vaccine, can reduce the incidence of shingles by half. Women should wait at least three months after receiving the vaccine before trying to get pregnant.
Zika Virus (Zika Fever)
The Zika virus is transmitted by the bite of an infected Aedes mosquito. Symptoms and signs of a Zika virus infection include conjunctivitis, headache, joint pain, fever, rash, and muscle aches. Treatment for Zika virus infections aims to alleviate symptoms.
Is Whooping Cough (Pertussis) Contagious?
Whooping cough (pertussis) is a highly contagious respiratory infection caused by Bordetella pertussis. Whooping cough symptoms include severe coughing fits and whooping sound produced during inhalation. The bacteria spreads via airborne droplets produced during sneezing or coughing. There is a whooping cough vaccine that is typically administered during childhood vaccinations.
Treatment & Diagnosis
Medications & Supplements
- tetanus toxoid injection (Tetanus Toxoid Absorbed)
- diphtheria-tetanus-pertussis-haemophilus vaccine-injection, Tetramune
- What Vaccines Are Given in Childhood?
- diphtheria and tetanus toxoids combined (pediatric) - injection
- diphtheria and tetanus toxoids combined (adult) - injection
- diphtheria/tetanus/acellular pertussis (pediatric) - injection, Daptacel, Infanrix, Tripedia
Prevention & Wellness
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.