- Irritable Bowel Syndrome (IBS) Slideshow Pictures
- Digestive Disease Myths
- Irritable Bowel Syndrome (IBS) Quiz
- What is dicyclomine, and how does it work (mechanism of action)?
- What brand names are available for dicyclomine?
- Is dicyclomine available as a generic drug?
- Do I need a prescription for dicyclomine?
- What are the side effects of dicyclomine?
- What is the dosage for dicyclomine?
- Is dicyclomine safe to take if I'm pregnant or breastfeeding?
- What else should I know about dicyclomine?
What is dicyclomine, and how does it work (mechanism of action)?
Dicyclomine is a drug that is used for treating irritable bowel syndrome (IBS). Dicyclomine is in a class of drugs called anticholinergics. Anticholinergic drugs block the effects of acetylcholine, the chemical transmitter that nerves release in order to cause muscles to contract. They prevent contraction of muscles by blocking the acetylcholine receptors on the muscle cells. Anticholinergic drugs also have a direct relaxing effect on muscle. Dicyclomine is used to reduce contraction of the muscles in the intestines. Dicyclomine was approved by the FDA in 1950.
What are the side effects of dicyclomine?
Common side effects include:
- dry mouth,
- blurred vision,
- increased heart rate,
- heart palpitations,
- difficulty urinating, and
Other important side effects include:
Quick GuideIBS - Irritable Bowel Syndrome: Symptoms, Diet, Treatment
What is the dosage for dicyclomine?
The recommended starting oral dose of dicyclomine is 20 mg given 4 times daily. The dose can be increased to 40 mg 4 times daily. The recommended intramuscular injection is 10 to 20 mg 4 times daily. The intramuscular injection is only used for 1 to 2 days if a patient cannot take capsules or tablets.
Is dicyclomine safe to take if I'm pregnant or breastfeeding?
There are no adequate studies of the effect of dicyclomine in pregnant women at recommended doses (80-160 mg/day). Observation of women who received dicyclomine (up to 40 mg/day) containing products during the first trimester of pregnancy did not reveal any increased risk of harm to the fetus.
Dicyclomine is excreted into breast milk. Since there have been reports of apnea (cessation of breathing) when dicyclomine has been given to children, it should not be used by nursing mothers.
What else should I know about dicyclomine?
What preparations of dicyclomine are available?
Capsules: 10 mg. Tablets: 20 mg. Syrup: 10 mg/5 mL. Injection (Intramuscular): 10 mg/ mL
How should I keep dicyclomine stored?
Capsules, tablets, and injection should be stored at room temperature, between 15 C to 30 C (59 F to 86 F). Injection should be protected from freezing.
Dicyclomine (Bentyl) is a drug prescribed for the treatment of irritable bowel syndrome (IBS). Side effects, drug interactions, dosage, and pregnancy safety should be reviewed prior to taking this medication.
Multimedia: Slideshows, Images & Quizzes
Diverticulitis (Diverticulosis) Symptoms, Diet, Treatment
Diverticulitis (diverticulosis) is a condition in which the diverticulum or diverticula rupture in the colon causing infection....
IBS - Irritable Bowel Syndrome: Symptoms, Diet, Treatment
What is irritable bowel syndrome (IBS)? Learn about symptoms, causes, and foods that trigger IBS. Get lifestyle tips for managing...
Related Disease Conditions
Diverticulitis (Diverticulosis, Diverticular Disease)
Most people with diverticulosis have few if any symptoms at all. When people do experience signs and symptoms of diverticulosis...
Irritable Bowel Syndrome (IBS) Symptoms, Diet, Treatment, and Test
Irritable bowel syndrome (IBS) is a GI (gastrointestinal) disorder with signs and symptoms of: Abdominal...
Microscopic Colitis (Lymphocytic Colitis and Collagenous Colitis)
Microscopic colitis (lymphocytic colitis and collagenous colitis) is a disease of inflammation of the colon. Microscopic colitis...
Irritable Bowel Syndrome in Children (IBS)
Irritable bowel syndrome (IBS) in children is a functional gastrointestinal disorder with signs and symptoms of: Abdominal...
IBS Triggers (Prevention)
Irritable bowel syndrome (IBS) is a functional disease that can affect the quality of those who suffer from this condition....
IBS-D (Irritable Bowel Syndrome with Diarrhea)
IBS-D or irritable bowel syndrome with diarrhea refers to IBS with diarrhea. Symptoms of IBS-D include intestinal gas...
Treatment & Diagnosis
- Medication Disposal
- Dangers of Mixing Medications
- How To Reduce Your Medication Costs
- Pharmacy Visit, How To Get The Most Out of Your Visit
- Indications for Drugs: Approved vs. Non-approved
- Drugs: Buying Prescription Drugs Online Safely
- Drugs: The Most Common Medication Errors
- Generic Drugs, Are They as Good as Brand-Names?
Medications & Supplements
Daily Health News
Subscribe to MedicineNet's General Health Newsletter
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Top dicyclomine Related Articles
Anticholinergic or antispasmodic (generic name) drugs include prescription medications used to treat a variety of medical conditions like:
- muscle spasms,
- breathing problems,
- movement disorders,
- motion sickness,
- and gastrointestinal cramps.
Examples of anticholinergic (antispasmodic) drugs include:
- Parkinson's disease medications,
- Benadryl, antipsychotics,
- and Levsin.
Examples of anticholinergic drugs for overactive bladder include:
- and Sanctura.
Examples of anticholinergic antidepressant medications include:
- and Norpranmin.
Examples of anticholinergic muscle relaxants include:
- and Norflex.
Anticholinergic motion sickness medications include:
- and respiratory medications.
Anticholinergic drug side effects, drug interactions, storage, dosing, and pregnancy and safety information should be reviewed prior to taking any medication.
chlordiazepoxide hydrochloride, clidinium bromideChlordiazepoxide hydrochloride and clidinium bromide (Librax) is a prescription drug used as therapy for peptic ulcer disease and IBS (irritable bowel syndrome). Librax also may be useful in management of acute gastroenteritis (stomach flu). Side effects, drug interactions, dosage, storage, and pregnancy safety should be reviewed prior to taking this drug.
Diverticulitis SlideshowDiverticulitis (diverticulosis) is a condition in which the diverticulum or diverticula rupture in the colon causing infection. Change in diet and medical treatments such as antibiotics and surgery can ease the symptoms of diverticulitis (diverticulosis).
Most people with diverticulosis have few if any symptoms at all. When people do experience signs and symptoms of diverticulosis (diverticular disease) they may include
- abdominal pain,
- abdominal cramps,
- constipation, and
Diverticulitis is a condition in which diverticuli in the colon rupture. The rupture results in infection in the tissues that surround the colon. Treatment methods for diverticulitis includes prescription medications, and in some cases, diverticulitis surgery.
Drug InteractionsDrug interactions occur frequently. Get facts about the types of drug interactions, what substances or other things that may interact with drugs such as OTC drug and prescription drugs, vitamins, food(s) (grapefruit), and laboratory tests. Find out how to protect yourself from potential drug interactions.
Drugs: What You Should Know About Your DrugsImportant information about your drugs should be reviewed prior to taking any prescription drug. Side effects, drug interactions, warnings and precauctions, dosage, what the drug is used for, what to do if you miss a dose, how the drug is to be stored, and generic vs. brand names.
hyoscyamine, atropine, scopolamine, phenobarbitalHyoscyamine sulfate, atropine sulfate, scopolamine sulfate and phenobarbital (Donnatal, Donnatal Extentabs) is a medication prescribed for the treatment of abdominal pain, bloating, and cramps in patients with IBS (irritable bowel syndrome), and gastroenteritis. Side effects, drug interactions, warnings and precautions, and pregnancy safety should be reviewed prior to taking any medication.
IBS SlideshowWhat is irritable bowel syndrome (IBS)? Learn about symptoms, causes, and foods that trigger IBS. Get lifestyle tips for managing IBS through diet and with IBS medications.
IBS-D Irrititable Bowel Syndrome with Diarrhea
IBS-D or irritable bowel syndrome with diarrhea refers to IBS with diarrhea. Symptoms of IBS-D include
- intestinal gas (flatulence),
- loose stools,
- frequent stools,
- abdominal pain,
- diarrhea, and
New non-FDA approved IBS tests may help diagnose IBS and IBS-D. Treatment of IBS-D is geared to toward managing symptoms with diet, medication, and lifestyle changes.
Irritable Bowel Syndrome (IBS)
Irritable bowel syndrome (IBS) is a GI (gastrointestinal) disorder with signs and symptoms of:
- Abdominal pain
- Increased gas (flatulence)
- Abdominal cramping
- Food intolerance
Two new tests are now available that may help diagnose irritable bowel syndrome with diarrhea and constipation (IBS-M) and irritable bowel syndrome with diarrhea (IBS-D). Treatment for IBS includes diet changes, medications, and other lifestyle changes to manage symptoms.
Irritable Bowel Syndrome (IBS) Triggers, Prevention
Irritable bowel syndrome (IBS) is a functional disease that can affect the quality of those who suffer from this condition. People with IBS can make lifestyle changes that may modify or control the number and severity of episodes. Certain foods, medications, and hormone levels may trigger IBS episodes, for example:
- Fatty foods
- Dairy products
- Eating foods in large quantities
- Foods that contain high levels of sorbitol
- Foods that produce intestinal gas (broccoli, onions, cabbage, and beans)
- Physiological stress
- Some antibiotics
- Some antidepressants
- Medicine with sorbitol
- Menstrual pain
Exercise, diet, and other lifestyle changes can decrease IBS flares, and prevent the number and severity of IBS episodes of diarrhea and constipation.
Irritable Bowel Syndrome in Children
Irritable bowel syndrome (IBS) in children is a functional gastrointestinal disorder with signs and symptoms of:
- Abdominal pain
The cause of IBS is unknown, however, certain foods, stress, anxiety, and depression may contribute to the symptoms of IBS. There is no cure for IBS in children; however, medications, dietary changes, and stress management may relieve symptoms.
Lymphocytic ColitisMicroscopic colitis (lymphocytic colitis and collagenous colitis) is a disease of inflammation of the colon. Microscopic colitis is only visible when the colon's lining is examined under a microscope. The cause of microscopic colitis is not known. Symptoms of microscopic colitis are chronic watery diarrhea and abdominal pain or cramps. Microscopic colitis is diagnosed through biopsies of several areas of the colon. There is no standardized treatment for microscopic colitis; however, eliminating NSAIDs, and treatment medications such as Imodium, Lomotil, Petpo-Bismol, Entocort EC, and mesalamine (Asacol) have been helpful in some individuals.