Delirium refers to a state of severe confusion and rapid changes in brain function that comes on suddenly. It can be associated with hallucinations and hyperactivity, and the sufferer is inaccessible to normal contact. Delirium can occur due to a wide variety of causes, including head injury, drug use or withdrawal, poisonings, brain tumors, infections, and metabolic disturbances. A urinary tract infection or pneumonia, for example, may lead to delirium in older people. The prognosis of delirium depends upon the underlying cause of the condition. Delirium can also occur as a result of mental illness. Symptoms can include
- changes in alertness or level of consciousness,
- confusion,
- drowsiness,
- incontinence,
- delusions,
- changes in speech,
- emotional changes,
- decreases in memory,
- concentration problems,
- disorientation,
- disorganized thinking, and
- changes in perception.
Delirium is sometimes mistaken for depression or dementia.
Other causes of delirium
- Alcohol Withdrawal
- Bacterial Infection
- Brain Infections/Abscesses
- Decompression Sickness
- Diabetic Ketoacidosis
- Drug Overdose
- Drug Withdrawal
- Electrolyte Imbalance
- Infection of the Brain or CNS
- Lipid Storage Diseases
- Liver Failure
- Malnutrition
- Medication Toxicity
- Medications
- Poisoning
- Renal Failure
- Respiratory Failure
- Severe Hemorrhage
- Sleep Deprivation
- Thyroid Storm
- Vascular Dementia
- Viral Infection
- Wernicke-Korsakoff Syndrome

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Alzheimer's disease is a common cause of dementia. Symptoms and warning signs of Alzheimer's disease include memory loss, difficulty performing familiar tasks, disorientation to time and place, misplacing things, and more. The biggest risk factor for Alzheimer's disease is increased age. Treatment for Alzheimer's is often targeted toward decreasing the symptoms and progression of the disease.
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Stroke
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Teen Drug Abuse
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Kasper, D.L., et al., eds. Harrison's Principles of Internal Medicine, 19th Ed. United States: McGraw-Hill Education, 2015.