D-Mannose

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What other names is D-mannose known by?

Carubinose, D-Manosa, Mannose, Seminose.

What is D-mannose?

D-mannose is a kind of sugar that is related to glucose.

D-mannose is used for preventing urinary tract infections (UTIs) and treating carbohydrate-deficient glycoprotein syndrome, an inherited metabolic disorder.

Insufficient Evidence to Rate Effectiveness for...

  • Treating a rare inherited disorder called carbohydrate-deficient glycoprotein syndrome type 1b. Some reports suggest that taking D-mannose supplements improves protein loss, liver function, low blood sugar, and blood clotting disorders in people with this condition.
  • Preventing urinary tract infections (UTIs).
  • Other conditions.
More evidence is needed to rate the effectiveness of D-mannose for these uses.

Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, and Insufficient Evidence to Rate (detailed description of each of the ratings).

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How does D-mannose work?

D-mannose might treat the deficiency caused by a genetic defect that causes abnormal breakdown and production of mannose. D-mannose might prevent certain kinds of bacteria from sticking to the walls of the urinary tract and causing infection.

Are there safety concerns?

D-mannose appears to be safe for most adults. It can cause loose stools and bloating. In high doses, it might harm the kidneys.

Special Precautions & Warnings:

Pregnancy and breast-feeding: Not enough is known about the use of D-mannose during pregnancy and breast-feeding. Stay on the safe side and avoid use.

Diabetes: Some research suggests that D-mannose might make blood sugar control more difficult in people with diabetes.

Dosing considerations for D-mannose.

The appropriate dose of D-mannose depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for d-mannose. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

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Reviewed on 3/29/2011 12:35:40 PM

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