- What Are They
- Side Effects
- Drug Interactions
- Pregnancy & Breastfeeding
Cyclobenzaprine vs. Xanax
- Cyclobenzaprine and Xanax (alprazolam) are used to relieve muscle spasms.
- Cyclobenzaprine is used with rest and physical therapy for short-term relief of muscle spasms associated with acute painful muscle and skeletal conditions.
- Xanax is mainly used to treat anxiety disorders and panic attacks.
- Brand names for cyclobenzaprine include Flexeril, Amrix, and Fexmid.
- Cyclobenzaprine and Xanax belong to different drug classes. Cyclobenzaprine is a muscle relaxant and Valium is a benzodiazepine.
- Side effects of cyclobenzaprine and Xanax that are similar include drowsiness, dry mouth, fatigue, headaches, and constipation.
- Side effects of cyclobenzaprine that are different from Xanax include dizziness, nausea, blurred vision, unpleasant taste, nervousness, confusion, acid reflux, and abdominal pain or discomfort.
- Side effects of Xanax that are different from cyclobenzaprine include memory problems, speech problems, weight changes, and addiction (dependency).
- Withdrawal symptoms such as insomnia, headaches, nausea, vomiting, lightheadedness, sweating, anxiety, fatigue, and seizures (in severe cases) may occur if you suddenly stop taking Xanax.
What is cyclobenzaprine? What is Xanax?
Cyclobenzaprine is a muscle relaxant used for short-term relief of muscle spasms associated with acute painful muscle and skeletal conditions, along with rest and physical therapy. Cyclobenzaprine is indicated for short-term use, up to two or three weeks. Cyclobenzaprine relieves muscle spasm when the spasm is due to local problems in the muscle itself and not in the nerves that control the muscles. Cyclobenzaprine achieves its beneficial effect through a complex mechanism within the nervous system, probably in the brainstem.
Xanax (alprazolam) is a benzodiazepine type anti-anxiety medication used to treat anxiety disorders and panic attacks. Other benzodiazepines include diazepam (Valium), clonazepam (Klonopin), lorazepam (Ativan), flurazepam (Dalmane), and others. Xanax and other benzodiazepines act by enhancing the effects of the neurotransmitter gamma-aminobutyric acid (GABA) in the brain. It is believed that excessive activity in the brain may cause anxiety or other psychiatric disorders.
What are the side effects of cyclobenzaprine and Xanax?
Cyclobenzaprine side effects
The most common side effects of cyclobenzaprine include:
Other reported side effects include:
- Blurred vision,
- Unpleasant taste
- Acid reflux
- Abdominal pain or discomfort
Possible serious side effects include:
Xanax side effects
The most common side effects of Xanax taken at lower doses are:
Other side effects include:
- Memory problems
- Speech problems
- Changes in weight
- Addiction (dependency)
- Dry mouth
What are the withdrawal symptoms of Xanax?
Withdrawal Addiction is more likely to occur at high doses given over prolonged periods. Abrupt discontinuation of alprazolam after prolonged use can lead to symptoms of withdrawal such as:
Seizures can occur in more severe cases of withdrawal. Consequently, patients on alprazolam for extended periods of time should slowly taper the medication under a doctor's supervision rather than abruptly stopping the medication.
What is the dosage of cyclobenzaprine vs. Xanax?
The recommended dose of cyclobenzaprine dose is 5 or 10 mg three times daily using immediate release tablets or 15 or 30 mg once daily using extended release tablets.
- The starting dose for treating anxiety is 0.25-0.5 mg 3 to 4 times daily using immediate release tablets. The dose may be increased every 3-4 days to a maximum dose of 4 mg daily.
- The starting dose for treating panic attacks is 0.5 mg 3 times daily. Doses can be increased every 3-4 days but by no more than 1 mg daily.
- The effective dose for preventing panic attacks may be as high as 10 mg daily for some patients. The starting dose when using extended release tablets to treat panic disorder is 0.5 mg once daily and the average dose is 3-6 mg once daily.
- Alprazolam may be taken with or without food.
What drugs interact with cyclobenzaprine and Xanax?
Cyclobenzaprine drug interactions
- Cyclobenzaprine is chemically related to the tricyclic class of antidepressants, for example, amitriptyline (Elavil, Endep), nortriptyline Pamelor). As such, it should not be taken with or within two weeks of any monoamine oxidase (MAO) inhibitor, for example, isocarboxazid (Marplan), phenelzine (Nardil), tranylcypromine (Parnate), and procarbazine (Matulane). High fever, convulsions, and even death can occur when these drugs are used together.
- Cyclobenzaprine interacts with other medications and drugs that slow the brain's processes, such as
Xanax drug interactions
- Ketoconazole (Nizoral), itraconazole (Sporanox), nefazodone (Serzone), cimetidine (Tagamet), and fluvoxamine (Luvox) increase concentrations in the blood of alprazolam and therefore may increase the side effects of alprazolam.
- Alprazolam interacts with alcohol and medications (for example, barbiturates, and narcotics) that suppress activity in the brain by suppressing activity more and causing sedation.
- Carbamazepine and rifampin reduce the effect of alprazolam by increasing metabolism and elimination of alprazolam in the liver.
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Are cyclobenzaprine and Xanax safe to use while pregnant or breastfeeding?
- There are no adequate studies of cyclobenzaprine in pregnant women. However, studies in animals suggest no important effects on the fetus. Cyclobenzaprine therefore can be used in pregnancy if the physician feels that it is necessary.
- It is not known whether cyclobenzaprine is secreted in milk. However, since it is related to the tricyclic antidepressants, some of which are excreted in breast milk, caution is advised in using this medication in women who are breastfeeding.
Cyclobenzaprine and Xanax (alprazolam) are used to relieve muscle spasms. Cyclobenzaprine is used with rest and physical therapy for short-term relief of muscle spasms associated with acute painful muscle and skeletal conditions. Xanax is mainly used to treat anxiety disorders and panic attacks.
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Muscle spasms are involuntary muscle contractions that come on suddenly and are usually quite painful. Dehydration, doing strenuous exercise in a hot environment, prolonged muscle use, and certain diseases of the nervous system may cause muscle spasms. Symptoms and signs of a muscle spasm include an acute onset of pain and a possible bulge seen or felt beneath the skin where the muscle is located. Gently stretching the muscle usually resolves a muscle spasm.
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- Myositis Muscle (Pain and Inflammation) Serious Drug Interactions
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Medications & Supplements
- alprazolam - oral, Xanax
- cyclobenzaprine - oral, Flexeril
- Alprazolam (Xanax) vs. Temazepam (Restoril)
- Hydroxyzine vs. Xanax
- Alprazolam vs. Diazepam
- Buspirone vs. Xanax
- Anxiolytics (for Anxiety) Drug Class Side Effects
- Baclofen vs. Flexeril (Side Effects and Interactions)
- alprazolam (Xanax)
- cyclobenzaprine (Flexeril, Amrix, Fexmid)
- Side Effects of Flexeril (cyclobenzaprine)
- Xanax vs. Valium
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Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Top Cyclobenzaprine flexeril vs Xanax alprazolam Related Articles
alprazolam (Xanax)Alprazolam is a member of the benzodiazepine family, which are sedatives that cause dose-related depression of the central nervous system. Alprazolam is used for the treatment of anxiety disorders and panic attacks, which cause unrealistic worry and apprehension, restlessness, aches, trembling, shortness of breath, smothering sensation, palpitations, sweating, cold clammy hands, lightheadedness, flushing, exaggerated startle responses, problems concentrating, and insomnia.
It is important to be aware of the drug interactions related to alprazolam, effects on pregnancy and nursing mothers, as well as common side effects on the user.
cyclobenzaprine (Flexeril, Amrix, Fexmid)
Cyclobenzaprine (Fexmid, Amrix, Flexeril) is a drug prescribed for the short-term relief of muscle spasms associated with acute painful muscle and skeletal conditions. Common side effects include dry mouth, fatigue, and headaches. Possible serious side effects include stroke, heart attacks, and heat stroke.
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Hamstring Muscle PictureThe prominent tendons at the back of the knee. See a picture of Hamstring Muscle and learn more about the health topic.
Muscle CrampsMuscle cramps are involuntarily and forcibly contracted muscles that do not relax. Extremely common, any muscles that have voluntary control, including some organs, are subject to cramp. Since there is such variety in the types of muscle cramps that can occur, many causes and preventative medications are known. Stretching is the most common way to stop or prevent most muscle cramps.
Muscle Cramps (Charley Horse) and Muscle SpasmsWhat are the differences between muscle spasms and cramps? Learn about the causes of muscle spasms and cramps (charley horse) in the calf, leg, and more.
Muscle Cramps: Foods That Help and Prevent CrampingOne way to prevent muscle cramps is to get enough of these nutrients: potassium, sodium, calcium, and magnesium. They’re called electrolytes, and you can find them in these foods.
Muscle Pain (Myofascial Pain Syndrome)Muscle pain (myofascial pain syndrome) is muscle pain in the body's soft tissues due to injury or strain. Symptoms include muscle pain with tender points and fatigue. Treatment usually involves physical therapy, massage therapy, or trigger point injection.
Muscle SpasmsMuscle spasms are involuntary muscle contractions that come on suddenly and are usually quite painful. Dehydration, doing strenuous exercise in a hot environment, prolonged muscle use, and certain diseases of the nervous system may cause muscle spasms. Symptoms and signs of a muscle spasm include an acute onset of pain and a possible bulge seen or felt beneath the skin where the muscle is located. Gently stretching the muscle usually resolves a muscle spasm.
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