Corneal Disease: Symptoms & Signs

Medically Reviewed on 5/26/2021

Corneal disease refers to problems with the cornea, the clear layer in the front of the eye. There are many types of corneal disease with different causes.

Signs and symptoms of corneal disease depend to some extent on the type of corneal disease and the specific cause. Associated symptoms and signs can include

Causes of corneal disease

Corneal disease may be caused by infections (bacterial, fungal, or viral infections), trauma or scarring, dystrophies or degenerative disorders, autoimmune diseases, allergic reactions, nutritional deficiencies, benign or malignant tumors, or thinning of the cornea. Other conditions of the eye can also cause secondary damage to the cornea.

Other corneal disease symptoms and signs


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Jameson, J. Larry, et al. Harrison's Principles of Internal Medicine, 20th Ed. New York: McGraw-Hill Education, 2018.