Diseases of the marrow and blood can be debilitating or fatal, but for certain diseases, a treatment method is to implant some healthy bone marrow from a genetically compatible donor into a patient in the hope it will grow and replace the diseased marrow. Often, the patient’s own cancerous marrow is destroyed prior to restoring the patient’s marrow with the new healthy donor cells. Read more: What Conditions Do You Need a Bone Marrow Transplant for? Article
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Related Disease Conditions
Sickle Cell Disease (Anemia)
Sickle cell anemia (sickle cell disease), a blood disease which shortens life expectancy, is caused by an inherited abnormal hemoglobin. Symptoms of sickle cell anemia may include bacterial infections, painful swelling of the hands and feet, fever, leg ulcers, fatigue, anemia, eye damage, and lung and heart injury. Treatment for sickle cell anemia aims to manage and prevent the worst manifestations of the disease and focuses on therapies that block red blood cells from stacking together, which can lead to tissue and organ damage and pain.
Leukemia is a type of cancer of the blood cells in which the growth and development of the blood cells are abnormal. Strictly speaking, leukemia should refer only to cancer of the white blood cells (the leukocytes) but in practice it can apply to malignancy of any cellular element in the blood or bone marrow, as in red cell leukemia (erythroleukemia).
Non-Hodgkin's lymphoma is cancer of the lymphatic system, a vital part of the body's immune system. Symptoms and signs include swollen lymph nodes, fever, night sweats, coughing, weakness, chest pain, unexplained weight loss, and abdominal pain. Treatment depends on which type of non-Hodgkin's lymphoma one has, the stage of the cancer, one's age, how fast the cancer is growing, and whether one has other health problems.
Beta Thalassemia is the most familiar type of thalassemia. Thalassemia is not just one disease but rather a complex series of genetic (inherited) disorders all of which involve underproduction of hemoglobin. Beta thalassemia major symptoms include pale skin, irritability, growth retardation, swelling of the abdomen, and jaundice. Beta thalassemia treatments include directly relieving the symptoms of the illness.
Hodgkin's and Non-Hodgkin's Lymphoma: Differences and Similarities
Both Hodgkin's disease (sometimes referred to as Hodgkin's lymphoma) and non-Hodgkin's lymphoma are cancers that originate in a type of white blood cell known as a lymphocyte, an important component of the body's immune system.
Mantle Cell Lymphoma (MCL)
Mantle cell lymphoma (MCL) is a rare form of non-Hodgkin's lymphoma. It is not known what causes MCL. MCL signs and symptoms include fever, enlarged spleen and liver, fatigue, and weight loss. Treatment of MCL incorporates radiotherapy and chemotherapy. MCL has a poor prognosis as it typically is diagnosed in a late stage.
Leukoplakia is a white or gray patch that develops on the tongue or inside the cheek. Causes of Leukoplakia may include irritation from rough teeth fillings or crowns, chronic smoking, sun exposure to the lips, or HIV or AIDS.
Burkitt lymphomas are types of non-Hodgkin's lymphoma that affect the bone marrow and central nervous system. There are multiple types of Burkitt lymphoma. Gene mutations, malaria, and Epstein-Barr virus (EBV) may increase the risk of these cancers. Symptoms of Burkitt lymphoma may include nausea, vomiting, headache, fatigue, enlarged lymph nodes, and many other symptoms. Diagnosis involves lab testing, imaging studies, patient history, and cytogenic evaluation. There are multiple staging systems used to stage Burkitt lymphoma. Treatment consists of chemotherapy. The prognosis of the cancer tends to be more favorable in children than in adults.
MPS I (Mucopolysaccharidosis Type I, Hurler Syndrome)
MPS I (also referred to as mucopolysaccharidosis Type I or Hurler syndrome) is a genetic, inherited condition that involves chromosome number 4. Symptoms of MPS I include Thick lips Eye problems Chronic nasal discharge Enlarged spleen or other abdominal organs Joint stiffness Coarsening of facial features There is no cure for MPS I, but signs and symptoms may be managed with enzyme replacement therapy and surgery to improve symptoms.
Childhood Acute Lymphoblastic Leukemia (ALL)
Childhood acute lymphoblastic leukemia is the most common type of cancer in children. Symptoms and signs include fever, easy bruising, bone or joint pain, weakness, loss of appetite, and painless lumps in the neck, underarm, stomach, or groin. Treatment depends upon staging and may include chemotherapy, radiation, or stem cell transplant.
Treatment & Diagnosis
- Leukemia FAQs
- Cancer FAQs
- Evolution of Treatment for a Rare Type of Leukemia
- Gleevec and Chronic Myeloid Leukemia
- How Familes Cope with a Leukemia Diagnosis
- Coping with a Bad Disease - Community Counts
- A Family's Leukemia Diary - Coping
- Is Multiple Myeloma the Same as Leukemia?
- Can Folic Acid Prevent Leukemia?
- Does Folic Acid Prevent Leukemia?
- Chronic Myelogenous Leukemia (CML)
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