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Does codeine cause side effects?
Codeine is habit forming (addictive). Mental and physical dependence can occur but are unlikely when used for short-term pain relief. If codeine is suddenly withdrawn after prolonged use, withdrawal symptoms may develop.
Drug interactions of codeine include alcohol and other sedatives, drugs that stimulate and also block opioid receptors (for example, pentazocine), anticholinergic drugs, and monoamine oxidase inhibitors (MAOIs).
Using codeine during pregnancy can cause opioid withdrawal syndrome in the newborn, which may be life-threatening if not treated. Small amounts of codeine are secreted in breast milk, but the risk of adverse events in the infant is small.
What are the important side effects of codeine?
The most frequent side effects of codeine include:
- Shortness of breath
- Allergic reactions
- Abdominal pain
Serious side effects of codeine include:
Codeine side effects list for healthcare professionals
The most frequent adverse reactions include lightheadedness, dizziness, sedation, nausea, and vomiting. These effects seem to be more prominent in ambulatory than in non ambulatory patients, and some of these adverse reactions may be alleviated if the patient lies down.
Can codeine cause addiction and withdrawal symptoms?
Controlled Substance: Codeine phosphate is a Schedule II narcotic.
Although much less potent in this regard than morphine, codeine can produce drug dependence a.d. therefore, has the potential for being abused. Patients given 60 mg codeine every 6 hours for 2 months usually show some tolerance and mild withdrawal symptoms. Development of the dependent state is recognized by an increased tolerance to the analgesic effect and the appearance of purposive phenomena (complaints, pleas, demands, or manipulative actions) shortly before the time of the next scheduled dose. A patient in withdrawal should be treated in a hospital environment. Usually, it is necessary only to provide supportive care with administration of a tranquilizer to suppress anxiety. Severe symptoms of withdrawal may require administration of a replacement narcotic.
What drugs interact with codeine?
Codeine in combination with other narcotic analgesics, general anesthetics, phenothiazines, tranquilizers, sedative-hypnotics, or other CNS depressants (including alcohol) has additive depressant effects. When s.c. combination therapy is contemplated, the dosage of one or both agents should be reduced.
Codeine is a narcotic (opioid) pain reliever and cough suppressant similar to morphine and hydrocodone used to relieve mild to moderately severe pain and to suppress cough. Common side effects of codeine include dizziness, nausea, vomiting, shortness of breath, sedation, allergic reactions, constipation, abdominal pain, rash, and itching.
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Related Disease Conditions
Cough: 19 Tips on How to Stop a Cough
Coughing is a reflex that helps a person clear their airways of irritants. There are many causes of an excessive or severe cough including irritants like cigarette and secondhand smoke, pollution, air fresheners, medications like beta blockers and ACE inhibitors, the common cold, GERD, lung cancer, and heart disease.Natural and home remedies to help cure and soothe a cough include staying hydrated, gargle salt water, use cough drops or lozenges, use herbs and supplements like ginger, mint, licorice, and slippery elm, and don't smoke. Over-the-counter products (OTC)to cure and soothe a cough include cough suppressants and expectorants, and anti-reflux drugs. Prescription drugs that help cure a cough include narcotic medications, antibiotics, inhaled steroids, and anti-reflux drugs like proton pump inhibitors or PPIs, for example, omeprazole (Prilosec), rabeprazole (Aciphex), and pantoprazole (Protonix).
Chronic cough is a cough that does not go away and is generally a symptom of another disorder such as asthma, allergic rhinitis, sinus infection, cigarette smoking, GERD, postnasal drip, bronchitis, pneumonia, medications, and less frequently tumors or other lung disease. Chronic cough treatment is based on the cause, but may be soothed natural and home remedies.
Cold and Cough Medicine for Infants and Children
The safety of giving infants and children over-the-counter (OTC) cold and cough medicine is important for caregivers to understand. While there is no "gold standard" recommendation for giving infants and children OTC cold and cough medicine for fever, aches, cough, and runny nose, a few standards have been recommended. The American Academy of Pediatrics recommends that OTC cold and cough medicine only be used in children age four years and older. The American College of Chest Physicians recommend that these medicines only be used in children age 15 years and older. The FDA recommends that OTC cold and cough medicine be used in children 2 years of age and older. However, there is agreement in regard to which OTC medications should not be used in children under the age of four (or the age of two, depending upon which guidelines are used), and they are 1) certain antihistamines like brompheniramine, chlorpheniramine maleate, and diphenhydramine (Benadryl); 2) cough expectorants (guaifenesin); 3) cough suppressants (dextromethorphan, DM); and 4) decongestants (pseudoephedrine and phenylephrine). Aspirin should never be given to infants, children, and adolescents due to the possibility of a rare, but often severe and even fatal illness called Reye's syndrome. REFERENCES:FDA. "Most Young Children with a Cough or Cold Don't Need Medicines." July 18, 2017. FDA. "Use Caution When Giving Cough and Cold Products to Kids." Updated: Nov 04, 2016.
Whooping Cough (Pertussis)
Whooping cough (pertussis) is a highly contagious respiratory infection caused by the bacteria Bordetella pertussis. There are an estimated 300,000 plus deaths annually from whooping cough (pertussis). Whooping cough commonly affects infants and young children but can be prevented with immunization with the vaccine. First stage whooping cough symptoms are a runny nose, sneezing, low-grade fever, a mild cough with the cough gradually becoming more severe. After one to two weeks, the second stage of whooping cough begins.
Chronic pain is pain (an unpleasant sense of discomfort) that persists or progresses over a long period of time. In contrast to acute pain that arises suddenly in response to a specific injury and is usually treatable, chronic pain persists over time and is often resistant to medical treatments.
Children's Cough Causes and Treatments
Children's cough causes include infection, acid reflux, asthma, allergies or sinus infection, whooping cough, and exposure to irritants. Treatment for a child's cough include cough medicine for children over the age of four.
What Are the 7 More Dangerous Medicines to Mix?
Some drug interactions can have serious side effects, while others may be lethal. You should avoid dangerous drug mistakes like mixing alcohol and opioids, warfarin and acetaminophen and few others.
What Is Substance Use Disorder?
Substance use disorder (or drug addiction) is a psychiatric disorder in people. In the disorder, people uncontrollably use a substance (legal or illegal drugs or medications) despite harmful consequences.
Treatment & Diagnosis
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Medications & Supplements
- codeine phosphate - injection
- acetaminophen/codeine - oral, Tylenol-Codeine No.3, Tylenol-
- Oxycodone vs. Codeine
- codeine (for Pain)
- Oxycodone vs. Hydrocodone
- Codeine vs. Vicodin
- Types of Addiction and Substance Abuse Medications
- Kloxxado (naloxone hydrochloride)
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Professional side effects list, drug interactions, and addiction sections courtesy of the U.S. Food and Drug Administration