Cluster headaches are headaches that typically cause severe pain and occur on one side of the head, often around or behind the eye. The pain occurs in cyclic patterns referred to as clusters. Overall, cluster headaches are not as common as other types of headaches. Cluster headaches affect men more often than women.
Signs and symptoms of cluster headaches include severe pain on one side of the head around the eye. The pain may radiate into the forehead, jaw, gum line, or into the teeth. Other associated symptoms and signs can include
- excessive tearing of the eye,
- runny nose,
- eyelid drooping,
- eyelid swelling, or
- redness of the eye.
Cause of cluster headaches
Doctors do not understand the exact cause of cluster headaches.
Other cluster headache symptoms and signs
- Droopy Eyelids
- Excessive Tearing of the Eye
- Eyelid Swelling
- Pain That Radiates to the Forehead, Teeth, Gum Line, or Jaw
- Red Eyes
- Runny Nose
- Severe Pain on One Side of the Head Around the Eye
Main Article on Cluster Headache Symptoms and Signs

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Examples of Medications for Cluster Headache Symptoms and Signs
- lidocaine spray - mucous membrane, Xylocaine
- lithium (Lithobid)
- Melatonin
- sumatriptan, Imitrex, Alsuma, Imitrex STATdose System, Sumavel DosePro
- topiramate, Topamax, Qudexy XR, Topamax Sprinkle, Topiragen, Trokendi XR
- valproic acid, divalproex, Depakote, Depakote Sprinkle, Depakote ER, Depakene, Depacon, Stavzor
- verapamil (Calan, Verelan, Verelan PM [Discontinued: Isoptin, Isoptin SR, Covera-HS])
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Migraines and Headaches Resources
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