- Side Effects
- Drug Interactions
- Pregnancy & Breastfeeding
- What Else to Know
Generic Name: clotrimazole
Brand Name: Lotrimin AF, Mycelex, Trivagizole
Discontinued Brand Names: Gyne-Lotrimin (DC), Alevazol, Desenex, Lotrimin
Drug Class: Antifungals, Other
What is clotrimazole, and what is it used for?
Clotrimazole is an anti-fungal medication related to fluconazole (Diflucan), ketoconazole (Nizoral), itraconazole (Sporanox), and miconazole (Micatin, Monistat).
Clotrimazole prevents the growth of several types of fungi by preventing interfering with the production of the membrane that surrounds fungal cells. It is used topically on the skin, inserted vaginally, or allowed to dissolve in the mouth for local fungal infections.
Clotrimazole is used for the treatment of local fungal infections due to Candida albicans, including the following:
- vaginal yeast infections ,
- oral thrush,
- tinea versicolor,
- tinea pedis ("athlete's foot"),
- tinea cruris ("jock itch") or
- tinea corporis.
What are the side effects of clotrimazole?
The most commonly noted side effects associated with clotrimazole include:
- local redness,
- hives, or
- burning at the area of application.
Other side effects include nausea and vomiting, which may be caused by the oral forms.
What drugs interact with clotrimazole?
Inform your doctor of all medications you are currently taking, who can advise you on any possible drug interactions. Never begin taking, suddenly discontinue, or change the dosage of any medication without your doctor’s recommendation.
- Clotrimazole topical has no listed severe interactions with any other drugs.
- Clotrimazole topical has no listed serious interactions with any other drugs.
- Clotrimazole topical has no listed moderate interactions with any other drugs.
- Clotrimazole topical has no listed minor interactions with any other drugs.
The drug interactions listed above are not all of the possible interactions or adverse effects. For more information on drug interactions, visit the RxList Drug Interaction Checker.
It is important to always tell your doctor, pharmacist, or health care provider about all prescription and over-the-counter medications you use, as well as the dosage for each, and keep a list of the information. Check with your doctor or healthcare provider if you have any questions about the medication.
What is the dosage for clotrimazole?
The troche (lozenge) should slowly dissolve in the mouth. One troche is administered 5 times daily for 14 days. Clotrimazole cream, lotion, or solution is applied to the affected and surrounding skin areas, generally twice daily in the morning and evening.
- The vaginal cream is inserted via applicator once daily, preferably at night, for 7 consecutive days.
- The 100 mg vaginal suppository is inserted once daily, preferably at bedtime, for 7 consecutive days.
- The 200 mg vaginal suppository is inserted once daily for 3 days, preferably at bedtime.
IMAGESBrowse our medical image collection of allergic skin disorders such as psoriasis and dermatitis and more caused by allergies See Images
Pregnancy and breastfeeding
- Clotrimazole is very poorly absorbed into the blood and the body after application to the skin or the vagina. Studies in women in their second or third trimesters of pregnancy have demonstrated no ill effects. No data is available on pregnant women during their first trimester.
- It is not known if clotrimazole is secreted in breast milk.
What else should I know about clotrimazole?
What preparations of clotrimazole are available?
- Topical cream, solution or lotion: 1%
- Buccal troche: 10 mg
- Vaginal suppositories: 100 and 200 mg
- Vaginal cream: 1% and 2%
How should I keep clotrimazole stored?
- Cream, lotion, solution and troche should be stored between 20 C to 25 C (68 F to 77 F). Vaginal suppositories should be stored between 15 C to 30 C (59 F to 86 F).
- CDC Warns of Potentially Fatal Bacterial Illness on U.S. Gulf Coast
- Helping Others as Volunteers Helps Kids 'Flourish': Study
- FDA Approves Pfizer's RSV Shot for Older Adults
- What to Do When Tough-to-Treat Lymphoma Strikes During Pregnancy
- Rate of Pregnant U.S. Women Who Have Diabetes Keeps Rising
- More Health News »
Clotrimazole is a drug prescribed to treat local fungal infections such as vaginal yeast infections, oral thrush, athlete's foot, and jock itch. The most commonly noted side effects associated with clotrimazole include local redness, stinging, blistering, peeling, swelling, itching, hives, or burning at the area of application. Clotrimazole has no known drug interactions. Consult your doctor if pregnant or breastfeeding.
Multimedia: Slideshows, Images & Quizzes
Fungal Skin Infections: Types, Symptoms, and Treatment
Fungal skin infections and fungal nail infections produce symptoms like red, itchy, circular rashes and thick, discolored, flaky...
Picture of Ringworm Tinea Corporis (Faciei)
Ringworm infection on a 51-year-old woman's skin. Ringworm (tinea) is a disease caused by a fungal infection of the skin. It can...
Picture of Ringworm Tinea Pedis
Close-up of athlete's foot (tinea pedis) on the foot of a 66year old man. See a picture of Ringworm Tinea Pedis and learn more...
Picture of Tinea Versicolor
Tinea versicolor is a fungal infection that causes small patches of discolored spots on your skin. It's also called pityriasis...
Yeast Infection Quiz: Symptoms & Treatment
How much do you know about vaginal yeast infections? Learn the causes, symptoms, and treatments of a yeast infection with the...
Picture of Athlete's Foot 2
Athlete's foot is a fungus that causes itching, redness, and cracking. See a picture of Athlete's Foot and learn more about the...
Picture of Yeast Infections (Thrush in Babies)
Thrush is a yeast infection that causes white patches in the mouth and on the tongue. See a picture of Yeast Infection (Thrush)...
Picture of Types of Ringworm
Ringworm is a common skin disorder otherwise known as tinea. See a picture of Types of Ringworm and learn more about the health...
Picture of Athlete's Foot 1
Athlete's foot is caused by a fungus that grows on or in the top layer of skin. See a picture of Athlete's Foot and learn more...
Picture of Baby Yeast Infections
Thrush is a yeast infection that causes white patches in the mouth and on the tongue. See a picture of Baby Yeast Infections and...
Related Disease Conditions
Jock itch is an itchy red rash that appears in the groin area. The rash may be caused by a bacterial or fungal infection. People with diabetes and those who are obese are more susceptible to developing jock itch. Antifungal shampoos, creams, and pills may be needed to treat fungal jock itch. Bacterial jock itch may be treated with antibacterial soaps and topical and oral antibiotics.
The term "ringworm" refers to a fungal infection on the surface of the skin. A physical examination of the affected skin, evaluation of skin scrapings under the microscope, and culture tests can help doctors make the appropriate distinctions. A proper diagnosis is essential to successful treatment. The different types of ringworm include the following: tinea barbae, tinea capitis, tinea corporis, tinea cruris, tinea faciei, tinea manus, tinea pedis, and tinea unguium.
Thrush (Oral Candidiasis)
Thrush is an infection of the mouth caused by the Candida fungus. Symptoms of thrush include pain or difficulty swallowing, a feeling that food gets stuck in the throat, and fever. Treatment of thrush depends on the cause and severity of the infection. Infants, toddlers, and children with thrush often do not require treatment.
Yeast Infections: How Do You Know When It Is Healing?
Vaginal yeast infections are the most frequent, causing itching, redness, discharge, and pain. Most yeast infections resolve within a week after therapy.
Vaginal Yeast Infection
Vaginal yeast infections in women are caused by an organism called Candida albicans. Symptoms of a vaginal yeast infection include vaginal pain with urination, vaginal discharge, odor, and itching. Treatment is generally OTC medications. A man can contract a yeast infection from his female sexual partner. Symptoms of a yeast infection in men include penile itching. Treatment is with oral or topical medication.
Yeast Infection vs. Diaper Rash in Infants, Toddlers, and Children
Diaper rash in infants, babies, toddlers, and children is caused by Candida, the most common type of fungus. Signs and symptoms of diaper rash includes red, elevated skin that may be visible under and in the creases of the skin, groin, or anus. Yeast diaper rash is not painful. Treatments for diaper rash include antibiotic creams, lotions, natural home remedies, over-the-counter (OTC) medicine, and oral antibiotics. Yeast infections in infants, babies, toddlers, and children can cause diaper rash and thrush. Signs and symptoms of thrush include thick, white lacy patches on top of a red base that can form on the tongue, palate, or elsewhere inside the palate. Treatment for yeast infections caused by Candida fungi are similar to the treatments for diaper rash. If Candida gets into the bloodstream of an individual they may get sick with or without a fever. If the Candida infection spreads throughout the body up to 45% of people may die. Even with common mouth thrush can cause critical illness and may be more resistant to normal treatment.
Dandruff (seborrhea) is a skin disorder that results from neither too much moisture nor too much oil. Dandruff can be treated with shampoos that contain tar, salicylic acid, zinc, selenium sulfide, or ketoconazole.
Athlete's foot (tinea pedis) is a skin infection caused by the ringworm fungus. Symptoms include itching, burning, cracking, peeling, and bleeding feet. Treatment involves keeping the feet dry and clean, wearing shoes that can breathe, and using medicated powders to keep your feet dry.
Is a Yeast Infection Contagious?
Yeast is a fungus that has many types. A type of yeast that can cause infection in humans is called Candida. Candida can infect the mouth, vagina, penis, or other areas of the body. Symptoms of yeast infections depend on the area infected, however, may include itching, bumps on the skin, a reddish rash, or patches of skin that ooze a clear or yellow liquid. Most yeast infections are not contagious even though they are caused by a fungus.
Is Ringworm Contagious?
A fungus causes ringworm. Ringworm can be transmitted from person to person. Animals may also spread ringworm. Ringworm causes an itchy, ring-shaped red rash with hair loss. Treatment incorporates the use of topical medication.
What Is the Fastest Way To Get Rid of a Yeast Infection?
Learn what medical treatments can help ease your yeast infection symptoms and speed up your recovery. Learn how to safely get rid of a yeast infection while pregnant.
Yeast infections vs. STDs in Men and Women
STDs, also termed sexually transmitted diseases, are infections that are mainly transmitted to others during direct sexual contact. A yeast infection is the invasion and multiplication of a fungus (yeast) in or on the body.
Oral Thrush in Children
Yeast infections are caused by an overgrowth of a type of fungus called Candida. Oral thrush is a yeast infection of the mouth and throat. Oral thrush and yeast infections are treated orally or topically with an antifungal antibiotic called nystatin.
Sickle Cell Disease (Anemia)
Sickle cell anemia (sickle cell disease), a blood disease that shortens life expectancy, is caused by inherited abnormal hemoglobin. Symptoms of sickle cell anemia may include bacterial infections, painful swelling of the hands and feet, fever, leg ulcers, fatigue, anemia, eye damage, and lung and heart injury. Treatment for sickle cell anemia aims to manage and prevent the worst manifestations of the disease and focuses on therapies that block red blood cells from stacking together, which can lead to tissue and organ damage and pain.
Will Jock Itch Go Away on Its Own?
Although jock itch is a curable condition, it does not go away on its own and can lead to complications if left untreated.
What Is the Fastest Way To Cure Jock Itch?
Learn what medical treatments can help ease your jock itch symptoms and help speed up your recovery.
How Do You Get Rid of a Yeast Infection In Your Mouth (Oral Thrush, Candidiasis)?
Learn what medical treatments can ease a yeast infection in your mouth, ease the symptoms of oral thrush, and speed up your recovery.
What Happens if You Don't Treat a Yeast Infection?
Yeast infections are contagious. They can be transmitted through sexual contact. Those with weak immunity have a high risk of the infection. Yeast infections can be vaginal (candidiasis), oral (thrush) or penile. Untreated yeast infections may spread to other areas, cause symptoms or pass to others.
Tinea versicolor is a fungus infection that mainly affects the skin of young people. Recognized by light or reddish brown spots, and areas lighter than the surrounding skin. Tinea versicolor is caused by yeast actually found in our skin. Factors like heat, humidity, and sweat help it proliferate in people, resulting in a rash that is not contagious to others.
What Is the Main Cause of a Yeast Infection?
Yeast infections are mainly caused by yeast-like fungus named Candida or Monilia. Yeast infections may affect the skin, mouth or vagina. Your doctor will use different methods of testing yeast infections depending on the area of your infection or symptoms.
How Long Does Oral Thrush Last Without Treatment?
Most people with good immunity can rid themselves of oral thrush within a week to 10 days.
Yeast Infection vs. Urinary Tract Infection (UTI)
Candida albicans typically causes vaginal yeast infections. Bacterial infections typically cause urinary tract infections (UTIs). Thick white cottage-cheese like vaginal discharge characterizes vaginal yeast infections. Painful, frequent urination characterize urinary tract infections. Antifungal medications treat yeast infections while prescription antibiotics treat UTIs.
Ringworm vs. Eczema
While ringworm is a fungal infection, and eczema is a skin condition, both are characterized by itchiness. Eczema patches are leathery while ringworm involves ring formation on the skin. Over-the-counter antifungals treat ringworm. Topical creams and ointments treat eczema.
What Conditions Can Be Mistaken for a Yeast Infection?
Around 75% of women experience at least one yeast infection at some point in their lives. Conditions that can be mistaken for a yeast infection include STDs, bacterial vaginosis, skin conditions, and UTIs.
Is Jock Itch (Tinea Cruris) Contagious?
Jock itch is a fungal infection in the groin area that causes a raised, itchy, red rash. Jock itch can typically be treated with antifungal medications. People may need to seek medical care for jock itch if the groin area becomes swollen, tender, if red streaks appear, or if the lymph nodes become swollen.
Yeast Infection vs. Bacterial Vaginosis (BV)
Yeast infections and bacterial vaginosis (BV) both cause vaginal discharge. Yeast infection discharge is thick, white, and had a cottage cheese consistency. BV discharge is whitish-gray and is thinner. Vaginal odor, irritation, and pain may also be present. Treatment of yeast infections includes over-the-counter and prescription antifungals. BV treatment involves antibiotics.
How Can I Treat a Yeast Infection While Pregnant?
Vaginal yeast infections are fungal infections that cause irritation and vaginal discharge. You can treat a vaginal yeast infection while pregnant with vaginal creams or suppositories, non-prescription medications, or medications that have been proven safe and effective in pregnant women.
How Serious Is A Yeast Infection During Pregnancy?
A yeast infection, also referred to as vaginal candidiasis, is a fungal infection caused by a type of fungus called candida. Even though a yeast infection is not a threat to you and your child, it can cause you extreme discomfort.
How Do I Check Myself for a Yeast Infection?
If you suspect you have a vaginal yeast infection, you may try an at-home vaginal pH test; however, this test will only help you rule out other infections.
What Is the Treatment for Tinea Corporis?
Tinea corporis, also called ringworm, is a superficial fungal infection of the skin that can be treated with topical antifungals. Learn about the causes, symptoms, and treatment of tinea corporis, and check out the center below for more medical references on fungal skin infections, including multimedia (slideshows, images, and quizzes), related diseases, treatment, diagnosis, medications, and prevention or wellness.
Is Clotrimazole Good for Fungal Infection?
Clotrimazole can be used to treat fungal skin infections and is typically applied topically. Learn about how to use clotrimazole as well as precautions and potential side effects. Check out the center below for more medical references on fungal skin infections, including multimedia (slideshows, images, and quizzes), related diseases, treatment, diagnosis, medications, and prevention or wellness.
How Do You Get Rid of Tinea Pedis?
Treatment for tinea pedis (athlete’s foot) typically includes prescription medications and home remedies. Check out the center below for more medical references on fungal skin infections, including multimedia (slideshows, images, and quizzes), related disease conditions, treatment and diagnosis, medications, and prevention or wellness.
Treatment & Diagnosis
- Yeast Infection FAQs
- How To Reduce Your Medication Costs
- Pharmacy Visit, How To Get The Most Out of Your Visit
- Indications for Drugs: Approved vs. Non-approved
- Drugs: Buying Prescription Drugs Online Safely
- Drugs: The Most Common Medication Errors
- Medication Disposal
- Dangers of Mixing Medications
- Can Yeast Infection Cause Low Back Pain?
- What Causes Yeast Infections (Vaginitis)?
- Does Stress Cause Yeast Infection?
- Does Douching Cause Yeast Infections?
- Tinea Versicolor Treatment
- Tinea Versicolor Symptoms and Signs
- Generic Drugs, Are They as Good as Brand-Names?
Medications & Supplements
- Which Antibiotic Is Best for An Ear Infection?
- clotrimazole lozenge - mucous membrane (oral), Mycelex
- clotrimazole/betamethasone - topical, Lotrisone
- Drugs: Questions to Ask Your Doctor or Pharmacist about Your Drugs
- Drug Interactions
- ketoconazole, Nizoral, Extina, Xolegel, Kuric
- itraconazole, Sporanox
- Lotrisone (clotrimazole and betamethasone topical cream and lotion)
- Side Effects of Lotrisone (clotrimazole and betamethasone)
- Vfend (voriconazole)
- Ertaczo (sertaconazole nitrate) Cream
Prevention & Wellness
Health Solutions From Our Sponsors
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.