- Tips to Fast Stress Relief
- Take the Panic Attacks Quiz!
- Generalized Anxiety Disorder (GAD) Slideshow
- What is clonazepam, and how does it work (mechanism of action)?
- What brand names are available for clonazepam?
- Is clonazepam available as a generic drug?
- Do I need a prescription for clonazepam?
- What are the uses for clonazepam?
- What are the side effects of clonazepam?
- What is the dosage for clonazepam?
- Which drugs or supplements interact with clonazepam?
- Is clonazepam safe to take if I'm pregnant or breastfeeding?
- What else should I know about clonazepam?
What is clonazepam, and how does it work (mechanism of action)?
- Clonazepam is an anti-anxiety medication in the benzodiazepine family, the same family that includes diazepam (Valium), alprazolam (Xanax), lorazepam (Ativan), flurazepam (Dalmane), and others. Clonazepam and other benzodiazepines act by enhancing the effects of gamma-aminobutyric acid (GABA) in the brain. GABA is a neurotransmitter (a chemical that nerve cells use to communicate with each other) that inhibits brain activity. It is believed that excessive activity in the brain may lead to anxiety or other psychiatric disorders. Clonazepam is primarily used for treating panic disorder and preventing certain types of seizures.
- The FDA approved clonazepam in June 1975.
What are the uses for clonazepam?
Clonazepam is used for:
What are the side effects of clonazepam?
The most common side effects associated with clonazepam are sedation, which is reported in approximately half of patients. Dizziness is reported in one-third of patients.
Other common side effects include:
- A feeling of depression,
- Loss of orientation,
- Unsteadiness, and
- Sleep disturbance
- Lack of inhibition
- Changes in sexual desire
Other serious side effects of clonazepam include:
- Respiratory depression
- Enlarged liver
- Withdrawal symptoms (if stopped suddenly)
- Increased heart rate
- Low blood pressure
- Blood disorders
Other serious adverse reactions:
- Antiepileptic medications have been associated with an increased risk of suicidal thinking and behavior. Anyone considering the use of antiepileptic drugs must balance this risk of suicide with the clinical need for the antiepileptic drug. Patients who begin antiepileptic therapy should be closely observed for clinical worsening, suicidal thoughts or unusual changes in behavior.
Latest Mental Health News
Daily Health News
What is the dosage for clonazepam?
The dose of clonazepam is tailored to the patient's needs.
- For seizures in adults the initial dose is 1.5 mg daily in 3 divided doses.
- Dosage may be increased by 0.5 to 1 mg daily every 3 days until seizures are controlled or side effects preclude further increases in dose.
- The maximum dose is 20 mg daily. The initial dose for panic disorders is 0.25 mg twice daily.
- The dose may be increased to the target dose of 1 mg daily after 3 days.
Which drugs or supplements interact with clonazepam?
Is clonazepam safe to take if I'm pregnant or breastfeeding?
- Clonazepam and other benzodiazepines have been associated with fetal damage, including congenital malformations, when taken by pregnant women in their first trimester. Clonazepam is best avoided in the first trimester and probably throughout pregnancy.
- Benzodiazepines are secreted in breast milk. Mothers who are breastfeeding should not take clonazepam.
What else should I know about clonazepam?
What preparations of clonazepam are available?
- Tablets: 0.5, 1, and 2 mg;
- Disintegrating tablets: 0.125, 0.25, 0.5, 1, and 2 mg.
How should I keep clonazepam stored?
Tablets should be kept at room temperature, between 15 C and 30 C (59 F and 86 F).
Multimedia: Slideshows, Images & Quizzes
Anxiety Disorder Pictures: Symptoms, Panic Attacks, and More with Pictures
Learn about generalized anxiety disorder (GAD). See if your worries are normal or something more by learning about symptoms,...
What Are Phobias? Agoraphobia, Social Anxiety Disorder, Other Fears
What are you afraid of? Learn about phobias such as agoraphobia, claustrophobia, arachnophobia, zoophobia, and more. Discover...
The Stages of Dementia: Alzheimer's Disease and Aging Brains
What are the symptoms of dementia? What causes dementia? Dementia includes many disorders, such as Lewy Body dementia,...
Restless Leg Syndrome (RLS) Quiz: Test Your Medical IQ
Restless leg syndrome (RLS), an annoying, sometimes painful disorder that keeps millions of people awake at night. What are the...
Epilepsy & Seizures Quiz: What Causes Seizures?
Do you know the difference between seizures and epilepsy? What are the types of seizures? Take the Epilepsy & Seizures Quiz to...
Panic Attacks (Panic Disorder) Quiz: Test Your Mental Health IQ
Could you suffer a panic attack? Take this Panic Attacks Quiz to learn causes, symptoms, and treatments for panic disorder. Use...
Related Disease Conditions
Restless Leg Syndrome
Restless leg syndrome (RLS) is a common cause for painful legs that typically eases with motion, and becomes worse and more noticeable at rest. This characteristic nighttime worsening can frequently lead to insomnia. Treatment of the symptoms of restless leg syndrome is generally with medication as well as treating any underlying condition causing restless leg syndrome.
Anxiety is a feeling of apprehension and fear characterized by symptoms such as trouble concentrating, headaches, sleep problems, and irritability. Anxiety disorders are serious medical illnesses that affect approximately 19 million American adults. Treatment for anxiety may incorporate medications and psychotherapy.
Seizures Symptoms and Types
Seizures are divided into two categories: generalized and partial. Generalized seizures are produced by electrical impulses from throughout the brain, while partial seizures are produced by electrical impulses in a small part of the brain. Seizure symptoms include unconsciousness, convulsions, and muscle rigidity.
Huntington's disease is the result of degeneration of neurons in areas of the brain. Huntington's disease is an inherited disorder. Early symptoms include mood swings, apathy, depression, and anger uncharacteristic of the individual. Judgement, memory, and other cognitive functions may become impaired. Presymptomatic testing is available for individuals who have a family history of Huntington's disease. Treatment includes medication and therapy for symptoms.
Panic attacks are sudden feelings of terror that strike without warning. These episodes can occur at any time, even during sleep. A person experiencing a panic attack may believe that he or she is having a heart attack or that death is imminent. The fear and terror that a person experiences during a panic attack are not in proportion to the true situation and may be unrelated to what is happening around them. Most people with panic attacks experience several of the following symptoms: racing heartbeat, faintness, dizziness, numbness or tingling in the hands and fingers, chills, chest pains, difficulty breathing, and a feeling of loss or control. There are several treatments for panic attacks.
Alcoholism and Alcohol Abuse
Alcoholism is a disease that includes alcohol craving and continued drinking despite repeated alcohol-related problems, such as losing a job or getting into trouble with the law. It can cause myriad health problems, including cirrhosis of the liver, birth defects, heart disease, stroke, psychological problems, and dementia. Counseling and a few medications can be effective for alcoholism treatment.
Epilepsy is a brain disorder in which the person has seizures. There are two kinds of seizures, focal and generalized. There are many causes of epilepsy. Treatment of epilepsy (seizures) depends upon the cause and type of seizures experienced.
Muscle Pain (Myofascial Pain Syndrome)
Muscle pain (myofascial pain syndrome) is muscle pain in the body's soft tissues due to injury or strain. Symptoms include muscle pain with tender points and fatigue. Treatment usually involves physical therapy, massage therapy, or trigger point injection.
Phobias are unrelenting fears of activities (social phobias), situations (agoraphobia), and specific items (arachnophobia). There is thought to be a hereditary component to phobias, though there may be a cultural influence or they may be triggered by life events. Symptoms and signs of phobias include having a panic attack, shaking, breathing troubles, rapid heartbeat, and a strong desire to escape the situation. Treatment of phobias typically involves desensitization, cognitive behavioral therapy, and medications such as selective serotonin reuptake inhibitors and beta-blockers.
Dystonia disorders cause involuntary movements and prolonged muscle contraction, resulting in twisting body motions, tremor, and abnormal posture. There are many forms of dystonia. Some types of dystonia respond to dopamine, or can be controlled with dedative-type medications, or surgery.
Why Do People Sleepwalk (Somnambulism)?
Sleepwalking is a condition in which an individual walks or does other activities while asleep. Factors associated with sleepwalking include genetic, environmental, and physiological. Episodes of sleepwalking may include quiet walking to agitated running. Conditions that may have similar symptoms of sleepwalking, but are not include night terrors, confusional arousals, and nocturnal seizures. Treatment of sleepwalking generally include preventative measures. Medication may be prescribed if necessary.
Separation anxiety disorder is a common childhood anxiety disorder that has many causes. Infants, children, older kids and adults can suffer from symptoms of separation anxiety disorder. Common separation anxiety treatment methods include therapy and medications. Factors that contribute to how quickly or successfully a child moves past separation anxiety by preschool age include how well the parent and child reunite, the skills the child and adult have at coping with the separation, and how well the adult responds to the infant's separation issues. For example, children of anxious parents tend to be anxious children.
What Causes Myoclonic Seizures in Babies?
Epileptic syndromes that cause myoclonic seizures usually begin in early childhood, and last throughout life, though milder forms may improve with adulthood. Doose syndrome (myoclonic-atonic epilepsy), Dravet syndrome (severe myoclonic epilepsy of infancy [SMEI]) and Lennox-Gastaut syndrome are all childhood epilepsy syndromes that may cause seizures in babies and toddlers.
Lewy Body Dementia (Dementia with Lewy Bodies)
Lewy body dementia (LBD or dementia with Lewy bodies) is one the most common causes of dementia. There are two types of LBD: 1) dementia with Lewy bodies, and 2) Parkinson's disease dementia. Symptoms of LBD are changes in a person's ability to think, movement problems, and sleep disorders. Treatment of LBD includes lifestyle changes, management of symptoms, palliative care, and medications to manage symptoms.
Tourette syndrome is disorder, which symptoms include involuntary facial tics, motor tics, and vocal tics. The cause of Tourette syndrome is not known. ADHD is associated with Tourette syndrome. Treatment includes medication, psychotherapy, and in severe cases surgery.
Mental health is an optimal way of thinking, relating to others, and feeling. All of the diagnosable mental disorders fall under the umbrella of mental illness. Depression, anxiety, and substance-abuse disorders are common types of mental illness. Symptoms and signs of mental illness include irritability, moodiness, insomnia, headaches, and sadness. Treatment may involve psychotherapy and medication.
Agoraphobia is a fear of being outside or of being in a situation from which escape would be impossible. Symptoms include anxiety, fear, disorientation, rapid heartbeat, diarrhea, or dizziness. Treatment may incorporate psychotherapy, self-exposure to the anxiety-causing situation, and medications such as SSRIs, benzodiazepines, and beta-blockers.
Febrile seizures, or convulsions caused by fever, can be frightening in small children or infants. However, in general, febrile seizures are harmless. Febrile seizure is not epilepsy. It is estimated that one in every 25 children will have at least one febrile seizure. It is important to know what to do to help your child if he/she has a febrile seizure. Some of the features of a febrile seizure include losing consciousness, shaking, moving limbs on both sides of the body, and lasts 1-2 minutes. Less commonly, a febrile seizure may only affect one side of the body.
Treatment & Diagnosis
- Catatonia (Catatonic Behavior)
- Seizure (Epilepsy)
- Borderline Personality Disorder
- Panic Attack
- Generalized Anxiety Disorder
- Lewy Body Dementia
- Doctor: Checklist to Take To Your Doctor's Appointment
- Huntington's Disease
- Periodic Limb Movement Disorder
- Epilepsy and Seizures FAQs
- Restless Leg Syndrome RLS FAQs
- Panic Attacks Disorder FAQs
- How To Reduce Your Medication Costs
- Pharmacy Visit, How To Get The Most Out of Your Visit
- Indications for Drugs: Approved vs. Non-approved
- Drugs: Buying Prescription Drugs Online Safely
- 10 Tips to Avoid Insomnia and Get a Good Night's Sleep
- Drugs: The Most Common Medication Errors
- Medication Disposal
- Dangers of Mixing Medications
- Generic Drugs, Are They as Good as Brand-Names?
Medications & Supplements
- Benzodiazepines (Benzodiazepine Drug Class)
- Anxiolytics (for Anxiety) Drug Class Side Effects
- Klonopin (clonazepam) vs. Valium (diazepam)
- alprazolam (Xanax)
- Alprazolam vs. Diazepam (Differences between Side Effects and Uses)
- diazepam (Valium, Diastat, Acudial, Diastat Pediatric, Diazepam Intensol)
- Drugs: Questions to Ask Your Doctor or Pharmacist about Your Drugs
- lorazepam (Ativan)
- Drug Interactions
- Klonopin (clonazepam) vs. Buspar (buspirone)
- Klonopin (clonazepam) vs. Ambien (zolpidem)
- What Are the Side Effects of Antiepileptic Drugs?
- triazolam (Halcion)
- Ativan (lorazepam) vs. Valium (diazepam)
- temazepam (Restoril)
- Klonopin (clonazepam) vs. Restoril (temazepam)
- Lyrica (pregabalin) vs. Klonopin (clonazepam)
- Klonopin (clonazepam) vs. Xanax (alprazolam)
- dimethyl fumarate (Tecfidera)
- Side Effects of Klonopin (clonazepam)
- teriflunomide (Aubagio)
Prevention & Wellness
- 3 Simple Steps Might Reduce Opioid OD Deaths
- Amnesia Affecting Some Opioid Abusers
- 1 in 6 U.S. Adults Takes a Psychiatric Drug: Study
- Girls Given Risky Meds Don't Get Contraceptive Advice
- Kids' ER Visits for Medicine Overdoses Dropping: Report
- Smoking, Pesticides Might Spur Rare 'Sleep-Kicking' Disorder
Health Solutions From Our Sponsors
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
FDA Prescribing Information