clobetasol propionate

Clobetasol propionate is a man-made corticosteroid that is used on the skin (topically). It is available as foam, shampoo, cream, gel, lotion, ointment, solution, and spray. It is similar to alclometasone (Aclovate), hydrocortisone valerate (Westcort), halobetasol (Ultravate) and several others. Topical clobetasol is used to treat certain scalp and skin conditions such as psoriasis, rashes, and dermatitis. Corticosteroids have potent anti-inflammatory actions and also suppress the immune response. Clobetasol is a very potent topical corticosteroid and should only be used for a short period of time. Long term use of topical clobetasol propionate can cause serious systemic side effects and should be avoided.

The FDA approved clobetasol on February 22, 1990.

Cormax, Embeline, Temovate, Olux, Clobex

GENERIC AVAILABLE: Yes

Yes

WARNING Clobetasol propionate is a very strong topical corticosteroid that causes serious side effects if absorbed into the blood. If absorbed into the blood stream prolonged use of clobetasol can depress the ability of the body's adrenal glands to produce corticosteroids. Abruptly stopping hydrocortisone in these individuals can cause symptoms of corticosteroid insufficiency. Therefore, topical corticosteroids should only be used for short term therapy and only applied to small area(s) of the body.

Clobetasol should be applied to the affected area(s) of the skin or scalp twice daily, once in the morning and once at night. As topical clobetasol is a very strong corticosteroid, treatment should be limited to two consecutive weeks and no more than 50 g or 50 ml per week.

There are no adequate and well-controlled studies evaluating the use of topical corticosteroids during pregnancy. Therefore, clobetasol and other topical corticosteroids should only be used during pregnancy if the potential benefit to the mother justifies the potential risk to the unborn baby. If used during pregnancy large amounts or use for long periods of time should be avoided.

It is not known whether clobetasol is secreted in breast milk. Therefore, topical corticosteroids should be used cautiously in nursing mothers.

What preparations of clobetasol scalp solution-topical are available?

Topical solution, Gel, Ointment, Liquid, Lotion, Spray, or Foam: 0.05%

How should I keep clobetasol scalp solution-topical stored?

Clobetasol should be stored at controlled room temperature between 20 C and 25 C (68 F and 77 F).