- What is clindamycin phosphate-vaginal cream, and how does it work (mechanism of action)?
- What are the side effects of clindamycin phosphate-vaginal cream?
- What is the dosage for clindamycin phosphate-vaginal cream?
- Which drugs or supplements interact with clindamycin phosphate-vaginal cream?
- Is clindamycin phosphate-vaginal cream safe to take if I'm pregnant or breastfeeding?
- What else should I know about clindamycin phosphate-vaginal cream?
What is clindamycin phosphate-vaginal cream, and how does it work (mechanism of action)?
Clindamycin is an antibiotic used for treating serious infections. It is effective against several types of bacteria such as Staphylococcus aureus, Streptococcus pneumoniae, and Staphylococcus epidermidis, and Propionibacterium acnes. It reduces growth of bacteria by interfering with their ability to make proteins. The FDA approved clindamycin for vaginal use in August 1972.
What brand names are available for clindamycin phosphate-vaginal cream?
Is clindamycin phosphate-vaginal cream available as a generic drug?
Do I need a prescription for clindamycin phosphate-vaginal cream?
What are the side effects of clindamycin phosphate-vaginal cream?
The most common side effects of clindamycin cream are:
What is the dosage for clindamycin phosphate-vaginal cream?
The recommended dose is one full applicator of clindamycin phosphate vaginal cream 2% intravaginally, preferably at bedtime, for 3 or 7 days in non-pregnant women and for 7 days in pregnant women.
Which drugs or supplements interact with clindamycin phosphate-vaginal cream?
Clindamycin give orally may act as a neuromuscular blocker. This means that it can increase the action of neuromuscular blocking drugs (for example, pancuronium and vecuronium). However, very little clindamycin is absorbed into the blood stream when given vaginally so the likelihood of drug interactions is less.
Is clindamycin phosphate-vaginal cream safe to take if I'm pregnant or breastfeeding?
The frequency of congenital abnormalities was not increased when pregnant women used clindamycin during the second and third trimesters, and clindamycin vaginal cream is approved for use during the second and third trimesters of pregnancy. Clindamycin should not be used during the first trimester of pregnancy unless it is clearly needed because it has not been properly evaluated during the first trimester.
Oral clindamycin is excreted in breast milk and should not be used by nursing mothers, or nursing should be stopped. It is not known whether clindamycin given vaginally is excreted in breast milk.
What else should I know about clindamycin phosphate-vaginal cream?
What preparations of clindamycin phosphate-vaginal cream are available?
STORAGE: Clindamycin should be stored at room temperature 20 C to 25 C (68 F to 77 F).
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Clindamycin phosphate vaginal cream (Cleocin) is used to treat symptoms of bacterial vaginosis. Side effects, drug interactions, and pregnancy safety information should be reviewed prior to using this medication.
Related Disease Conditions
Vaginal Yeast Infection (in Women and Men)
Vaginal yeast infections in women are caused by an organism called Candida albicans. Symptoms of a vaginal yeast infection include vaginal pain with urination, vaginal discharge, odor, and itching. Treatment is generally OTC medications. A man can contract a yeast infection from his female sexual partner. Symptoms of a yeast infection in men include penile itching. Treatment is with oral or topical medication.
Bacterial vaginosis is an abnormal vaginal condition with signs and symptoms of vaginal discharge, vaginal odor, and vaginal pain. Bacterial vaginosis results from an overgrowth of normal bacteria in the vagina. Although it may cause some disturbing symptoms (discharge and odor), it is not dangerous and cannot be passed by sex. Diagnosis becomes important to exclude serious infections like gonorrhea and Chlamydia. Many treatment options are available such as oral antibiotics and vaginal gels.
Pregnancy Planning (Tips)
Pregnancy planning is an important step in preparation for starting or expanding a family. Planning for a pregnancy includes taking prenatal vitamins, eating healthy for you and your baby, disease prevention (for both parents and baby) to prevent birth defects and infections, avoiding certain medications that may be harmful to your baby, how much weight gain is healthy exercise safety and pregnancy, travel during pregnancy.
Vancomycin-Resistant Enterococci (VRE)
Vancomycin-resistant enterococci (VRE) infection is the most common type of infection acquired by patients while hospitalized. Patients at risk for VRE are those who are already ill, and hospitalized, including individuals with diabetes, elderly, ICU patients, kidney failure patients, or patients requiring catheters. Enterococci can survive for months in the digestive tract and female genital tract. Other risk factors for acquiring VRE include those how have been previously treated with vancomycin and combinations of other antibiotics. Treatment of VRE is generally with other antibiotics other than vancomycin. Prevention of VRE can be achieved by proper hand hygiene.
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