- What is clindamycin and benzoyl peroxide gel, and how does it work (mechanism of action)?
- What are the side effects of clindamycin and benzoyl peroxide gel?
- What is the dosage for clindamycin and benzoyl peroxide gel?
- Which drugs or supplements interact with clindamycin and benzoyl peroxide gel?
- Is clindamycin and benzoyl peroxide gel safe to take if I'm pregnant or breastfeeding?
- What else should I know about clindamycin and benzoyl peroxide gel?
What is clindamycin and benzoyl peroxide gel, and how does it work (mechanism of action)?
Clindamycin/benzoyl peroxide is a combination of an antibiotic, clindamycin, and benzoyl peroxide, another drug that has antibacterial effects. Clindamycin/benzoyl peroxide is used topically (applied to the skin) for the treatment of pimples (acne). Both agents are active against Propionibacterium acnes, a bacterium which has been associated with acne. Clindamycin probably reduces acne by penetrating into the skin and killing bacteria that contribute to the formation of acne. Benzoyl peroxide works through several mechanisms. It kills the bacteria and promotes the growth of new skin cells. It also dries the skin. Increased cell growth leads to replacement of the pimples with new skin. Combaining clindamycin and benzoyl peroxide is more convenient than using them separately. The FDA approved clindamycin/benzoyl peroxide in December 2000.
What brand names are available for clindamycin and benzoyl peroxide gel?
Benzaclin, Acanya, Duac, Onexton
Do I need a prescription for clindamycin and benzoyl peroxide gel?
What are the side effects of clindamycin and benzoyl peroxide gel?
The most common side effect of clindamycin/benzoyl peroxide are:
Allergic reactions may also occur. Diarrhea, sometimes bloody, has been reported with topical clindamycin. This reaction, although quite rare, can be dangerous. Discontinuation is recommended if marked diarrhea develops.
What is the dosage for clindamycin and benzoyl peroxide gel?
Clindamycin/benzoyl peroxide should be applied to acne lesions at bedtime (Duac), once daily (Acanya), twice daily, morning and evening (Benzaclin), or as directed by a physician. Affected areas should be washed, rinsed with warm water, and patted dry before applying clindamycin/benzoyl peroxide.
Which drugs or supplements interact with clindamycin and benzoyl peroxide gel?
There are no known drug interactions with clindamycin/benzoyl peroxide.
Is clindamycin and benzoyl peroxide gel safe to take if I'm pregnant or breastfeeding?
Clindamycin/benzoyl peroxide has not been tested in pregnant women.
Clindamycin/benzoyl Peroxide has not been tested among nursing women. Orally ingested clindamycin is secreted into breast milk and may cause side effects in the infant. Mothers should decide whether to stop breastfeeding or discontinue clindamycin/benzoyl peroxide.
What else should I know about clindamycin and benzoyl peroxide gel?
What preparations of clindamycin and benzoyl peroxide gel are available?
Gel (clindamycin/benzoyl peroxide): 1%/ 5% or 1.2%/2.5%, 3.75%
How should I keep clindamycin and benzoyl peroxide gel stored?
The gel can be stored at room temperature, up to 25 C (77 F), for up to three months after it is dispensed by the pharmacy. Unused gel should be discarded after three months.
Latest Skin News
Daily Health News
Clindamycin and benzoyl peroxide gel (Benzaclin, Acanya, Duac) is a topical medication prescribed for the treatment of acne. Side effects, drug interactions, and pregnancy safety should be reviewed prior to taking this medication.
Related Disease Conditions
Acne is a localized skin inflammation as a result of overactivity of oil glands at the base of hair follicles. This inflammation, depending on its location, can take the form of a superficial pustule (contains pus), a pimple, a deeper cyst, congested pores, whiteheads, or blackheads. Treatments vary depending on the severity of the acne.
Pimple vs. Cold Sore
Pimples are areas of skin inflammation with pus in the center. Cold sores are fluid-filled blisters. Pimples are caused by bacterial overgrowth and inflammation. Cold sores are caused by infection with herpes simplex viruses (HSV-1 and HSV-2). Benzoyl peroxide and sometimes antibiotics treat acne. Antiviral medications accelerate the healing process of oral herpes.
Vancomycin-Resistant Enterococci (VRE)
Vancomycin-resistant enterococci (VRE) infection is the most common type of infection acquired by patients while hospitalized. Patients at risk for VRE are those who are already ill, and hospitalized, including individuals with diabetes, elderly, ICU patients, kidney failure patients, or patients requiring catheters. Enterococci can survive for months in the digestive tract and female genital tract. Other risk factors for acquiring VRE include those how have been previously treated with vancomycin and combinations of other antibiotics. Treatment of VRE is generally with other antibiotics other than vancomycin. Prevention of VRE can be achieved by proper hand hygiene.
What Is the Best Treatment for Impetigo?
Impetigo is a bacterial skin infection that causes a rash that forms blisters and can ooze pus, causing a crust. Impetigo can be caused by different kinds of bacteria, including strep and staph. Usually, impetigo is easy to treat and rarely leaves scarring.
Heart Attack Prevention
Heart disease and heart attacks can be prevented by leading a healthy lifestyle with diet, exercise, and stress management. Symptoms of heart attack in men and women include chest discomfort and pain in the shoulder, neck, jaw, stomach, or back. Women experience the same symptoms as men; however, they also may experience: Extreme fatigue Pain in the upper abdomen Dizziness Fainting Leading a healthy lifestyle with a heart healthy low-fat diet, and exercise can help prevent heart disease and heart attack.
Treatment & Diagnosis
- Medication Disposal
- Dangers of Mixing Medications
- How To Reduce Your Medication Costs
- Pharmacy Visit, How To Get The Most Out of Your Visit
- Indications for Drugs: Approved vs. Non-approved
- Drugs: Buying Prescription Drugs Online Safely
- Drugs: The Most Common Medication Errors
- What Are the Side Effects of Taking Antibiotics Long-Term?
- Antibiotics 101
- Generic Drugs, Are They as Good as Brand-Names?
Medications & Supplements
Prevention & Wellness
Health Solutions From Our Sponsors
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
FDA Prescribing Information