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What is clindamycin? What is clindamycin used for?
Clindamycin vaginal cream is indicated for the treatment of bacterial vaginosis (formerly referred to as Haemophilus vaginitis, Gardnerella vaginitis, nonspecific vaginitis, Corynebacterium vaginitis, or anaerobic vaginosis) in non-pregnant women.
Clindamycin in general is an antibiotic used for treating several other infections as well. It is effective against several types of bacteria such as Staphylococcus aureus, Streptococcus pneumoniae, and Staphylococcus epidermidis, and Propionibacterium acnes. It reduces growth of bacteria by interfering with their ability to make proteins.
The FDA approved clindamycin vaginal suppositories in November, 2004.
What brand names are available for clindamycin-vaginal suppository?
Is clindamycin-vaginal suppository available as a generic drug?
Do I need a prescription for clindamycin-vaginal suppository?
What are the side effects of vaginal clindamycin?
The most common side effects of clindamycin vaginal suppositories are:
- vaginal moniliasis, a fungal infection
- vulvovaginal disorder
- trichomonal vaginitis
Other side effects that may occur include:
Possible serious side effects of clindamycin include:
- Orally administered and injected clindamycin may cause severe colitis (inflammation of the colon).
- Vaginal formulations of clindamycin may be absorbed into the blood stream, and colitis with diarrhea or bloody diarrhea (including C.difficile colitis) have been reported with the use of clindamycin vaginal suppositories.
What is the dosage for vaginal clindamycin?
- Insert 1 suppository into the vagina at night for 3 days.
- Patients should avoid vaginal intercourse or vaginal products (such as tampons or douches) during treatment with clindamycin vaginal suppositories.
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Is vaginal clindamycin safe to take if I'm pregnant or breastfeeding?
- The frequency of congenital abnormalities was not increased when pregnant women used oral clindamycin during the second and third trimesters.
- Pregnant women who used clindamycin vaginal cream during the second trimester reported abnormal labor more frequently than those who received placebo.
- Clindamycin vaginal suppositories have not been properly evaluated during the first trimester of pregnancy. They should only be used during the first trimester of pregnancy when they are clearly needed.
- Oral clindamycin is excreted in breast milk and should not be used by nursing mothers or nursing should be stopped.
- It is not known whether clindamycin from vaginal suppositories is excreted in breast milk.
What else should I know about vaginal clindamycin?
What preparations of clindamycin-vaginal suppository are available?
- Suppositories: 100 mg
How should I keep clindamycin-vaginal suppository stored?
- Clindamycin vaginal suppositories should be stored at room temperature, 15 C – 30 C (59 F – 86 F).
Clindamycin phosphate vaginal suppository (Cleocin) is an antibiotic prescribed to treat bacterial vaginosis infection in women. Side effects, drug interactions, dosing, storage, and pregnancy and breastfeeding information should be reviewed prior to using this medication.
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Related Disease Conditions
Toxoplasmosis (toxo) is a parasitic infection that causes flu-like symptoms, swollen lymph nodes, and muscle aches and pains that may last from a few days to several weeks. Toxoplasmosis can be contracted by touching the hands to the mouth after gardening, cleaning a cat's litter box, or anything that came into contact with cat feces. Toxoplasmosis can also be contracted by eating raw or partly cooked meat, especially pork or lamb, or touching the hands to the mouth after contact with raw or undercooked meat.
Bacterial vaginosis is an abnormal vaginal condition with signs and symptoms of vaginal discharge, vaginal odor, and vaginal pain. Bacterial vaginosis results from an overgrowth of normal bacteria in the vagina. Although it may cause some disturbing symptoms (discharge and odor), it is not dangerous and cannot be passed by sex. Diagnosis becomes important to exclude serious infections like gonorrhea and Chlamydia. Many treatment options are available such as oral antibiotics and vaginal gels.
Vaginitis (Inflammation of the Vagina)
Vaginitis refers to inflammation of the vagina. Vaginitis can be caused by infections, menopause, or poor hygiene. Symptoms of vaginitis include vaginal itching, discharge, odor, pain, or discomfort. Treatment for vaginitis depends on the cause. Antibiotics may be necessary for some forms of vaginitis.
Vancomycin-Resistant Enterococci (VRE)
Vancomycin-resistant enterococci (VRE) infection is the most common type of infection acquired by patients while hospitalized. Patients at risk for VRE are those who are already ill, and hospitalized, including individuals with diabetes, elderly, ICU patients, kidney failure patients, or patients requiring catheters. Enterococci can survive for months in the digestive tract and female genital tract. Other risk factors for acquiring VRE include those how have been previously treated with vancomycin and combinations of other antibiotics. Treatment of VRE is generally with other antibiotics other than vancomycin. Prevention of VRE can be achieved by proper hand hygiene.
Vaginal Pain (Vulvodynia)
Vulvodynia or vaginal pain, genital pain is a condition in which women have chronic vulvar pain with no known cause. There are two types of vulvodynia, generalized vulvodynia and vulvar vestibulitis. Researchers are trying to find the causes of vulvodynia, for example, nerve irritation, genetic factors, hypersensitivity to yeast infections, muscle spasms, and hormonal changes.The most common symptoms of vaginal pain (vulvodynia) is burning, rawness, itching, stinging, aching, soreness, and throbbing. There are a variety of treatments that can ease the symptoms of vulvodynia (vaginal pain).
Yeast Infection vs. Bacterial Vaginosis (BV)
Yeast infections and bacterial vaginosis (BV) both cause vaginal discharge. Yeast infection discharge is thick, white, and had a cottage cheese consistency. BV discharge is whitish-gray and is thinner. Vaginal odor, irritation, and pain may also be present. Treatment of yeast infections includes over-the-counter and prescription antifungals. BV treatment involves antibiotics.
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