GENERIC NAME: CIMETIDINE - ORAL (sye-MET-uh-deen)
BRAND NAME(S): Tagamet
Medication Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage
USES: Cimetidine is used to treat ulcers of the stomach and intestines and prevent them from coming back after they have healed. This medication is also used to treat certain stomach and throat (esophagus) problems caused by too much stomach acid (e.g., Zollinger-Ellison syndrome, erosive esophagitis) or a backward flow of stomach acid into the esophagus (acid reflux disease/GERD). Decreasing extra stomach acid can help relieve symptoms such as stomach pain, heartburn, difficulty swallowing, persistent cough, and trouble sleeping. It can also prevent serious acid damage to your digestive system (e.g., ulcers, cancer of the esophagus).Cimetidine belongs to a class of drugs commonly called H2 blockers. It works by reducing the amount of acid in your stomach.This medication is also available without a prescription. It is used to treat occasional heartburn caused by too much acid in the stomach (also called acid indigestion or sour stomach). It is also used to prevent heartburn and acid indigestion caused by certain foods and beverages. If you are taking this medication for self-treatment, it is important to read the manufacturer's package instructions carefully so you know when to consult your doctor or pharmacist. (See also Precautions.)
HOW TO USE: Take this medication by mouth with or without food as directed by your doctor.The dosage and length of treatment are based on your medical condition and response to therapy. Follow your doctor's instructions carefully. If you are also taking antacids to relieve stomach pain as recommended by your doctor, separate them from this medication by at least 1 hour.Take this medication regularly as prescribed in order to get the most benefit from it. To help you remember, take it at the same time(s) each day. Do not increase your dose or take it more often than directed. Continue to take this medication for the prescribed length of treatment even if you are feeling better. Stopping treatment too early may delay the healing process.If you are using nonprescription cimetidine for self-treatment of acid indigestion or heartburn, take 1 tablet by mouth with a glass of water as needed. To prevent heartburn, take 1 tablet by mouth with a glass of water right before or up to 30 minutes before eating food or drinking beverages that cause heartburn. Do not take more than 2 tablets in 24 hours unless directed by your doctor. Do not take for more than 14 days in a row without talking with your doctor.Inform your doctor if your symptoms do not improve or if they worsen.
SIDE EFFECTS: Headache, dizziness, drowsiness, or diarrhea may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.If your doctor has directed you to use this medication, remember that he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.Tell your doctor immediately if any of these unlikely but serious side effects occur: mental/mood changes (e.g., agitation, confusion, depression, hallucinations), trouble urinating, muscle/joint pain, breast swelling/soreness in males, decreased sexual ability (with very high doses of this medication).Tell your doctor immediately if any of these rare but very serious side effects occur: easy bruising/bleeding, signs of infection (e.g., fever, persistent sore throat, cough, trouble breathing), fast/slow/irregular heartbeat, unusual tiredness, persistent nausea/vomiting, severe stomach/abdominal pain, dark urine, yellowing eyes/skin, change in the amount of urine.A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.In the US -Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
PRECAUTIONS: Before taking cimetidine, tell your doctor or pharmacist if you are allergic to it; or to other H2 blockers (e.g., famotidine, nizatidine, ranitidine); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.Before using this medication, tell your doctor or pharmacist your medical history, especially of: immune system problems, kidney problems, liver problems, certain lung diseases (chronic obstructive pulmonary disease-COPD), diabetes, other stomach problems (e.g., tumors).Some symptoms may actually be signs of a more serious condition. Get medical help right away if you have: heartburn with lightheadedness/sweating/dizziness, chest/jaw/arm/shoulder pain (especially with shortness of breath, unusual sweating), unexplained weight loss.In addition, before you self-treat with this medication, get medical help right away if you have any of these signs of a serious condition: trouble/pain swallowing food, bloody vomit, vomit that looks like coffee grounds, bloody/black stools, heartburn for over 3 months, frequent chest pain, frequent wheezing (especially with heartburn), nausea/vomiting, stomach pain.This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages.Do not use this medication to treat children younger than 12 unless directed by the doctor.Older adults may be more sensitive to the side effects of this drug, especially confusion and lung infection (pneumonia). Confusion can increase the risk of falling.Cimetidine should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor.Cimetidine passes into breast milk. Consult your doctor before breast-feeding.
DRUG INTERACTIONS: See also How to Use section.Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.This drug should not be used with the following medications because very serious interactions may occur: cisapride, dofetilide, epirubicin.If you are currently using any of these medications listed above, tell your doctor or pharmacist before starting cimetidine.Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: artemether, clopidogrel, carmustine, lumefantrine, metformin, moclobemide, moricizine, procainamide, quinidine, silver sulfadiazine, drugs removed from your body by certain liver enzymes (such as lidocaine, metoprolol, propranolol, tacrine, warfarin, zaleplon, anti-seizure drugs including carbamazepine and phenytoin, benzodiazepines including diazepam, calcium channel blockers including diltiazem, narcotic analgesics including codeine, tricyclic antidepressants including amitriptyline, theophylline and related drugs).Since cimetidine reduces the amount of acid in your stomach, it may also change the absorption of certain medications and affect how they work. Some examples of affected drugs include atazanavir, dasatinib, delavirdine, certain azole antifungals (such as itraconazole, ketoconazole), among others. Ask your doctor or pharmacist if any of the medications you take are affected by cimetidine and how to manage this interaction.Check the labels on all your medicines because they may contain nonsteroidal anti-inflammatory drugs (NSAIDs such as aspirin, ibuprofen, naproxen) that may cause stomach irritation/ulcers. Ask your pharmacist about the safe use of those products. Low-dose aspirin should be continued if prescribed by your doctor for specific medical reasons such as heart attack or stroke prevention (usually at dosages of 81-325 milligrams per day). Consult your doctor or pharmacist for more details.Cigarette smoking can affect this medication. Tell your doctor if you smoke and if you stop or start smoking while using this medication.This medication and similar H2 blockers (e.g., famotidine, nizatidine, ranitidine) are available both with and without a prescription. Do not take them at the same time.
OVERDOSE: If overdose is suspected, contact a poison control center or emergency room immediately. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include mental/mood changes, slurred speech, difficulty awakening.
- Kids With Autism Face Higher Odds of Vision Issues, But Many Don't Get Screened
- Mental Health Woes Double Women's Odds for Cervical Cancer
- Million-Person Study Finds Genes Common to Many Addiction Disorders
- Too Much Social Media Could Raise Risk for Eating Disorders
- Weaker Bones, Weakening Brain? Study Makes the Connection
- More Health News »
NOTES: Do not share this medication with others.Lifestyle changes such as stress reduction programs, stopping smoking, limiting alcohol, and diet changes (e.g., avoiding caffeine and spicy foods) may increase the effectiveness of this medication. Talk to your doctor or pharmacist about lifestyle changes that might benefit you.Laboratory and/or medical tests may be performed to monitor your progress or check for side effects. Consult your doctor for more details.
MISSED DOSE: If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.
STORAGE: Store in a tightly closed container at room temperature between 59-86 degrees F (15-30 degrees C) away from moisture and light. Do not store in the bathroom. Keep all medicines away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.
Information last revised February 2014. Copyright(c) 2014 First Databank, Inc.
Health Solutions From Our Sponsors
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.
Top cimetidine Related Articles
Chronic CoughChronic cough is a cough that does not go away and is generally a symptom of another disorder such as asthma, allergic rhinitis, sinus infection, cigarette smoking, GERD, postnasal drip, bronchitis, pneumonia, medications, and less frequently tumors or other lung disease.
Chronic cough treatment is based on the cause, but may be soothed natural and home remedies.
Chronic Rhinitis and Post-Nasal DripChronic rhinitis and post-nasal drip symptoms include an itchy, runny nose, sneezing, itchy ears, eyes, and throat. Seasonal allergic rhinitis (also called hay fever) usually is caused by pollen in the air. Perennial allergic rhinitis is a type of chronic rhinitis and is a year-round problem, often caused by indoor allergens, such as dust, animal dander, and pollens that may exist at the time. Treatment of chronic rhinitis and post nasal drip are dependent upon the type of rhinitis condition.
What Is Esophageal pH Monitoring?Esophageal pH monitoring is used to measure the reflux (regurgitation or backwash) of acid from the stomach into the esophagus and to diagnose gastroesophageal reflux disease (GERD). Side effects of the procedure are few but may include mild discomfort in the back of the throat while the catheter is placed, and swallowing.
Esophagus PictureThe esophagus is a muscular tube connecting the throat (pharynx) with the stomach. See a picture of the Esophagus and learn more about the health topic.
GERD (Acid Reflux, Heartburn)GERD (gastroesophageal reflux disease) is a condition in which the acidified liquid contents of the stomach backs up into the esophagus. The symptoms of uncomplicated GERD are:
- regurgitation, and
GERD QuizWho is at risk for developing GERD? Are you? Take this quiz to learn what GERD is, if you're at risk, and what you can do about it.
Heartburn is a burning sensation experienced from acid reflux (GERD). Symptoms of heartburn include chest pain, burning in the throat, difficulty swallowing, the feeling of food sticking in the throat, and a burning feeling in the chest.
Causes of heartburn include dietary habits, lifestyle habits, and medical causes.
Treatments for heartburn include lifestyle changes, OTC medication,prescription medication, and surgery.
Hiatal HerniaHiatal hernia is a condition in which a thin membrane of tissue connects the esophagus with the diaphragm becomes week, and a portion of the stomach slides up into the esophagus. Causes include obesity, pregnancy, straining during a bowel movement, aging, and ascites. There are generally no symptoms of a hiatal hernia, and it is discovered during another medical procedure to test for GERD, or other swallowing problems.
Hives (Urticaria)Hives, also called urticaria, is a raised, itchy area of skin. Most often the cause of hives is unknown. Sometimes it is a sign of an allergic reaction to food or medications, but the cause of the allergy (the allergen) is unknown. Dermatographism and swelling (angioedema) may accompany hives. Treatment to get rid of hives and alleviate symptoms typically includes antihistamines.
Cough: 19 Tips on How to Stop a CoughCoughing is a reflex that helps a person clear their airways of irritants. There are many causes of an excessive or severe cough including irritants like cigarette and secondhand smoke, pollution, air fresheners, medications like beta blockers and ACE inhibitors, the common cold, GERD, lung cancer, and heart disease.Natural and home remedies to help cure and soothe a cough include staying hydrated, gargle salt water, use cough drops or lozenges, use herbs and supplements like ginger, mint, licorice, and slippery elm, and don't smoke. Over-the-counter products (OTC)to cure and soothe a cough include cough suppressants and expectorants, and anti-reflux drugs. Prescription drugs that help cure a cough include narcotic medications, antibiotics, inhaled steroids, and anti-reflux drugs like proton pump inhibitors or PPIs, for example, omeprazole (Prilosec), rabeprazole (Aciphex), and pantoprazole (Protonix).
Peptic Ulcer (Stomach Ulcer)Peptic or stomach ulcers are ulcers are an ulcer in the lining of the stomach, duodenum, or esophagus. Ulcer formation is related to H. pylori bacteria in the stomach, use of anti-inflammatory medications, and cigarette smoking. Symptoms of peptic or stomach ulcers include abdominal burning or hunger pain, indigestion, and abdominal discomfort after meals. Treatment for stomach ulcers depends upon the cause.
Shock (Medical)Medical shock is a life-threatening medical condition. There are several types of medical shock, including:
- septic shock,
- anaphylactic shock,
- cardiogenic shock,
- hypovolemic shock, and
- neurogenic shock.
- heart attack,
- heart failure,
- heavy bleeding (internal and external),
- spinal cord injury,
- severe burns,
- chronic vomiting or