- What is ciclopirox, and how does it work (mechanism of action)?
- What are the uses for ciclopirox?
- What are the side effects of ciclopirox?
- What is the dosage for ciclopirox?
- Which drugs or supplements interact with ciclopirox?
- Is ciclopirox safe to take if I'm pregnant or breastfeeding?
- What else should I know about ciclopirox?
What is ciclopirox, and how does it work (mechanism of action)?
Ciclopirox is a synthetic broad-spectrum antifungal agent that inhibits the growth of dermatophytes, a type of fungus that grows on the skin, hair, and nails. When applied to skin a very small percentage is absorbed into the body. It was approved for use in the U.S. by the FDA in December 1999.
What brand names are available for ciclopirox?
Penlac, Loprox
Is ciclopirox available as a generic drug?
GENERIC AVAILABLE: Yes
Do I need a prescription for ciclopirox?
Yes
What are the uses for ciclopirox?
What are the side effects of ciclopirox?
Side effects of ciclopirox include:
What is the dosage for ciclopirox?
Ciclopirox is applied once or twice a day to affected areas depending on the condition being treated.

SLIDESHOW
Rosacea, Acne, Shingles, Covid-19 Rashes: Common Adult Skin Diseases See SlideshowWhich drugs or supplements interact with ciclopirox?
Use together with other medications for fungal infection is not recommended. Nail polish or other cosmetic products should not be used on the treated nails.
Is ciclopirox safe to take if I'm pregnant or breastfeeding?
When applied to skin a very small amount of ciclopirox is absorbed into the body. It is not known whether ciclopirox is excreted in breast milk. Because of a potential for side effects in the nursing infant, the physician must weigh the potential benefits and possible risks before prescribing ciclopirox to nursing mothers.
What else should I know about ciclopirox?
What preparations of ciclopirox are available?
Solution: 8%; Cream/lotion/gel: 0.77%; Shampoo: 1%
How should I keep ciclopirox stored?
Ciclopirox should be stored at room temperature, 15 C - 30 C (59 F - 86 F). Use or storage near heat or open flame should be avoided since the solution is flammable.
Summary
Ciclopirox (Penlac, Loprox) is a medication prescribed to treat mild to moderate finger or toenail fungus, ringworm, jock itch, athlete's foot, tinea versicolor, and seborrheic dermatitis. Review side effects, drug interactions, and dosage information prior to taking this medication.
Multimedia: Slideshows, Images & Quizzes
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Picture of Ringworm Tinea Corporis (Faciei)
Ringworm infection on a 51-year-old woman's skin. Ringworm (tinea) is a disease caused by a fungal infection of the skin. It can...
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Picture of Ringworm Tinea Pedis
Close-up of athlete's foot (tinea pedis) on the foot of a 66year old man. See a picture of Ringworm Tinea Pedis and learn more...
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Picture of Ringworm of the Hand
Ringworm may involve the hands, particularly the palms and the spaces between the fingers. See a picture of Ringworm of the Hand...
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Picture of Fungal Nail Infection
Nails that are infected with a fungus may become discolored (yellowish-brown or opaque), thick and brittle, and may separate from...
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Picture of Types of Ringworm
Ringworm is a common skin disorder otherwise known as tinea. See a picture of Types of Ringworm and learn more about the health...
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Picture of Ringworm Illustration
Ringworm is a fungal infection of the skin previously thought to be due to a parasite (worm). See a picture of Ringworm and learn...
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Picture of Ringworm
This superficial skin infection, also known as tinea, is caused by fungi called dermatophytes. See a picture of Ringworm and...
Related Disease Conditions
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Jock Itch
Jock itch is an itchy red rash that appears in the groin area. The rash may be caused by a bacterial or fungal infection. People with diabetes and those who are obese are more susceptible to developing jock itch. Antifungal shampoos, creams, and pills may be needed to treat fungal jock itch. Bacterial jock itch may be treated with antibacterial soaps and topical and oral antibiotics.
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Ringworm
The term "ringworm" refers to a fungal infection on the surface of the skin. A physical examination of the affected skin, evaluation of skin scrapings under the microscope, and culture tests can help doctors make the appropriate distinctions. A proper diagnosis is essential to successful treatment. The different types of ringworm include the following: tinea barbae, tinea capitis, tinea corporis, tinea cruris, tinea faciei, tinea manus, tinea pedis, and tinea unguium.
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Fungal Nails
Fungal nails (onychomycosis) may be caused by many species of fungi, but the most common is Trichophyton rubrum. Distal subungal onychomycosis starts as a discolored area at the nail's corner and slowly spread toward the cuticle. In proximal subungal onychomycosis, the infection starts at the cuticle and spreads toward the nail tip. Yeast onychomycosis is caused by Candida and may be the most common cause of fungal fingernail.
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Athlete's Foot
Athlete's foot (tinea pedis) is a skin infection caused by the ringworm fungus. Symptoms include itching, burning, cracking, peeling, and bleeding feet. Treatment involves keeping the feet dry and clean, wearing shoes that can breathe, and using medicated powders to keep your feet dry.
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Seborrheic Dermatitis
Seborrheic dermatitis is a chronic skin condition. Symptoms and signs include a red, scaling rash on the scalp, face, ears, and torso. Treatment often includes the use of a medicated shampoo and the application of a topical steroid lotion.
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Tinea Versicolor
Tinea versicolor is a fungus infection that mainly affects the skin of young people. Recognized by light or reddish brown spots, and areas lighter than the surrounding skin. Tinea versicolor is caused by yeast actually found in our skin. Factors like heat, humidity, and sweat help it proliferate in people, resulting in a rash that is not contagious to others.
Treatment & Diagnosis
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Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.