ciclopirox, Penlac, Loprox

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

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What is ciclopirox, and how does it work (mechanism of action)?

Ciclopirox is a synthetic broad-spectrum antifungal agent that inhibits the growth of dermatophytes, a type of fungus that grows on the skin, hair, and nails. When applied to skin a very small percentage is absorbed into the body. It was approved for use in the U.S. by the FDA in December 1999.

What brand names are available for ciclopirox?

Penlac, Loprox

Is ciclopirox available as a generic drug?

GENERIC AVAILABLE: Yes

Do I need a prescription for ciclopirox?

Yes

What are the side effects of ciclopirox?

Side effects of ciclopirox include:

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What is the dosage for ciclopirox?

Ciclopirox is applied once or twice a day to affected areas depending on the condition being treated.

Which drugs or supplements interact with ciclopirox?

Use together with other medications for fungal infection is not recommended. Nail polish or other cosmetic products should not be used on the treated nails.

Is ciclopirox safe to take if I'm pregnant or breastfeeding?

When applied to skin a very small amount of ciclopirox is absorbed into the body. It is not known whether ciclopirox is excreted in breast milk. Because of a potential for side effects in the nursing infant, the physician must weigh the potential benefits and possible risks before prescribing ciclopirox to nursing mothers.

What else should I know about ciclopirox?

What preparations of ciclopirox are available?

Solution: 8%; Cream/lotion/gel: 0.77%; Shampoo: 1%

How should I keep ciclopirox stored?

Ciclopirox should be stored at room temperature, 15 C - 30 C (59 F - 86 F). Use or storage near heat or open flame should be avoided since the solution is flammable.

Reference: FDA Prescribing Information

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Summary

Clopirox (Penlac, Loprox) is a medication prescribed to treat mild to moderate finger or toenail fungus, ringworm, jock itch, athlete's foot, tinea versicolor, and seborrheic dermatitis. Side effects, drug interactions, and dosing information should be reviewed prior to taking this medication.

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See more info: ciclopirox on RxList
Reviewed on 12/22/2015
References
Reference: FDA Prescribing Information

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