What is ciclopirox, and how does it work (mechanism of action)?

Ciclopirox is a synthetic broad-spectrum antifungal agent that inhibits the growth of dermatophytes, a type of fungus that grows on the skin, hair, and nails. When applied to skin a very small percentage is absorbed into the body. It was approved for use in the U.S. by the FDA in December 1999.

What brand names are available for ciclopirox?

Penlac, Loprox

Is ciclopirox available as a generic drug?

GENERIC AVAILABLE: Yes

Do I need a prescription for ciclopirox?

Yes

What are the uses for ciclopirox?

Ciclopirox is a medication prescribed to treat mild to moderate finger or toenail fungus, ringworm, jock itch, athlete's foot, tinea versicolor, and seborrheic dermatitis.

What are the side effects of ciclopirox?

Side effects of ciclopirox include:

What is the dosage for ciclopirox?

Ciclopirox is applied once or twice a day to affected areas depending on the condition being treated.

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Which drugs or supplements interact with ciclopirox?

Use together with other medications for fungal infection is not recommended. Nail polish or other cosmetic products should not be used on the treated nails.

Is ciclopirox safe to take if I'm pregnant or breastfeeding?

When applied to skin a very small amount of ciclopirox is absorbed into the body. It is not known whether ciclopirox is excreted in breast milk. Because of a potential for side effects in the nursing infant, the physician must weigh the potential benefits and possible risks before prescribing ciclopirox to nursing mothers.

What else should I know about ciclopirox?

What preparations of ciclopirox are available?

Solution: 8%; Cream/lotion/gel: 0.77%; Shampoo: 1%

How should I keep ciclopirox stored?

Ciclopirox should be stored at room temperature, 15 C - 30 C (59 F - 86 F). Use or storage near heat or open flame should be avoided since the solution is flammable.

Summary

Ciclopirox (Penlac, Loprox) is a medication prescribed to treat mild to moderate finger or toenail fungus, ringworm, jock itch, athlete's foot, tinea versicolor, and seborrheic dermatitis. Review side effects, drug interactions, and dosage information prior to taking this medication.

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You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

See more info: ciclopirox on RxList
Medically Reviewed on 8/7/2019
References
FDA Prescribing Information
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