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- What is chlordiazepoxide hydrochloride and clidinium bromide, and how does it work (mechanism of action)?
- What are the uses for chlordiazepoxide hydrochloride and clidinium bromide?
- What are the side effects of chlordiazepoxide hydrochloride and clidinium bromide?
- What is the dosage for chlordiazepoxide hydrochloride and clidinium bromide?
- Which drugs or supplements interact with chlordiazepoxide hydrochloride and clidinium bromide?
- Is chlordiazepoxide hydrochloride and clidinium bromide safe to take if I'm pregnant or breastfeeding?
- What else should I know about chlordiazepoxide hydrochloride and clidinium bromide?
What is chlordiazepoxide hydrochloride and clidinium bromide, and how does it work (mechanism of action)?
Chlordiazepoxide hydrochloride and clidinium bromide (Librax) combines the anti-anxiety action of chlordiazepoxide and the antispasmodic effects of clidinium. It also blocks the acid secretion of the gastrointestinal tract and inhibits the action of nerves that are very active in certain diseases. The FDA classifies the combination as possibly effective as additional therapy for treatment of peptic ulcers, irritable bowel syndrome (IBS), GI spasms and some intestinal infections.
What brand names are available for chlordiazepoxide hydrochloride and clidinium bromide?
Is chlordiazepoxide hydrochloride and clidinium bromide available as a generic drug?
GENERIC AVAILABLE: yes
Do I need a prescription for chlordiazepoxide hydrochloride and clidinium bromide?
What are the uses for chlordiazepoxide hydrochloride and clidinium bromide?
What are the side effects of chlordiazepoxide hydrochloride and clidinium bromide?
- Adverse reactions may include drowsiness, dizziness, and confusion. Nausea, constipation, and dry mouth may occur.
- Urinary hesitancy or retention are seen, particularly in the elderly.
- Skin eruptions and liver abnormalities are less common.
- Avoid driving or operating machinery while taking chlordiazepoxide hydrochloride/clidinium bromide because it reduces mental alertness.
What is the dosage for chlordiazepoxide hydrochloride and clidinium bromide?
Chlordiazepoxide hydrochloride/clidinium bromide may be taken with or without food. Take 1 to two capsules every 6 to 8 hours before meals and at bedtime.
Which drugs or supplements interact with chlordiazepoxide hydrochloride and clidinium bromide?
Chlordiazepoxide hydrochloride/clidinium bromide should not be used in people with glaucoma or urinary retention (difficulty urinating) due to benign prostatic hypertrophy (BPH) because clidinium blocks the action of choline, increasing intraocular pressure and causing difficulty urinating. Chlordiazepoxide has sedative effects and should not be combined with alcohol or other central nervous system depressants.
Is chlordiazepoxide hydrochloride and clidinium bromide safe to take if I'm pregnant or breastfeeding?
What else should I know about chlordiazepoxide hydrochloride and clidinium bromide?
What preparations of chlordiazepoxide hydrochloride and clidinium bromide are available?
Capsules: 5mg chlordiazepoxide hydrochloride and 2.5mg clidinium bromide.
How should I keep chlordiazepoxide hydrochloride and clidinium bromide stored?
Capsules should be stored at room temperature in a tightly close container.
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Chlordiazepoxide hydrochloride and clidinium bromide (Librax) is a prescription drug used as therapy for peptic ulcer disease and IBS (irritable bowel syndrome). Librax also may be useful in management of acute gastroenteritis (stomach flu). Review side effects, drug interactions, dosage, storage, and pregnancy safety information prior to taking this drug.
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Related Disease Conditions
Irritable Bowel Syndrome (IBS)
Irritable bowel syndrome (IBS) is a GI (gastrointestinal) disorder with signs and symptoms that include abdominal pain, bloating, increased gas (flatulence), abdominal cramping, diarrhea, constipation, and food intolerance.Two new tests are now available that may help diagnose irritable bowel syndrome with diarrhea and constipation (IBS-M) irritable bowel syndrome with diarrhea (IBS-D), and irritable bowel syndrome with constipation (IBS-C). Treatment for IBS includes diet changes, medications, and other lifestyle changes to manage symptoms.
How Are Hiccups Caused?
Hiccups are a sudden, involuntary contraction of the diaphragm muscle. In general hiccups are just a temporary condition. Some of the causes of hiccups include certain medications, surgery, eating or drinking too much, spicy foods, diseases or conditions that irritate the nerves controlling the diaphragm, strokes, brain tumors, liver failure, and noxious fumes. There are a variety of home remedies and treatments that can be used to get rid of hiccups.
Peptic Ulcer (Stomach Ulcer)
Peptic or stomach ulcers are ulcers are an ulcer in the lining of the stomach, duodenum, or esophagus. Ulcer formation is related to H. pylori bacteria in the stomach, use of anti-inflammatory medications, and cigarette smoking. Symptoms of peptic or stomach ulcers include abdominal burning or hunger pain, indigestion, and abdominal discomfort after meals. Treatment for stomach ulcers depends upon the cause.
Diverticulitis (Diverticulosis, Diverticular Disease)
Most people with diverticulosis have few if any symptoms at all. When people do experience signs and symptoms of diverticulosis (diverticular disease) they may include abdominal pain, abdominal cramps, diarrhea, constipation, and bloating. Diverticulitis is a condition in which diverticuli in the colon rupture. The rupture results in infection in the tissues that surround the colon. Treatment methods for diverticulitis includes prescription medications, and in some cases, diverticulitis surgery.
Stomach Flu (Gastroenteritis) Symptoms Signs, Treatment Remedies, Diet
Stomach flu (gastroenteritis) is a term referred used to describe a variety of gastrointestinal problems. The most common signs and symptoms of gastroenteritis are nausea, vomiting, diarrhea, and abdominal pain. The most common cause of gastroenteritis in the United States is Norovirus. Other causes of gastroenteritis include Rotavirus, Astrovirus, Adenovirus, and Sapovirus. There are bacterial causes of gastroenteritis such as Salmonella, Shigella, Campylobacter Aeromonas, E. coli, Clostridium, Vibrio, Campylobacter, and Yersinia spp. Parasites that cause gastroenteritis include Giardia, Cryptosporidium, Cyclospora, and Entamoeba. Treatment for gastroenteritis is generally home remedies such as keeping hydrated to prevent dehydration. At times, hospitalization may be necessary if dehydration occurs.
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Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.