- What is chlordiazepoxide hydrochloride and clidinium bromide, and how does it work (mechanism of action)?
- What are the uses for chlordiazepoxide hydrochloride and clidinium bromide?
- What are the side effects of chlordiazepoxide hydrochloride and clidinium bromide?
- What is the dosage for chlordiazepoxide hydrochloride and clidinium bromide?
- Which drugs or supplements interact with chlordiazepoxide hydrochloride and clidinium bromide?
- Is chlordiazepoxide hydrochloride and clidinium bromide safe to take if I'm pregnant or breastfeeding?
- What else should I know about chlordiazepoxide hydrochloride and clidinium bromide?
What is chlordiazepoxide hydrochloride and clidinium bromide, and how does it work (mechanism of action)?
Chlordiazepoxide hydrochloride and clidinium bromide (Librax) combines the anti-anxiety action of chlordiazepoxide and the antispasmodic effects of clidinium. It also blocks the acid secretion of the gastrointestinal tract and inhibits the action of nerves that are very active in certain diseases. The FDA classifies the combination as possibly effective as additional therapy for treatment of peptic ulcers, irritable bowel syndrome (IBS), GI spasms and some intestinal infections.
What brand names are available for chlordiazepoxide hydrochloride and clidinium bromide?
Is chlordiazepoxide hydrochloride and clidinium bromide available as a generic drug?
GENERIC AVAILABLE: yes
Do I need a prescription for chlordiazepoxide hydrochloride and clidinium bromide?
What are the uses for chlordiazepoxide hydrochloride and clidinium bromide?
What are the side effects of chlordiazepoxide hydrochloride and clidinium bromide?
- Adverse reactions may include drowsiness, dizziness, and confusion. Nausea, constipation, and dry mouth may occur.
- Urinary hesitancy or retention are seen, particularly in the elderly.
- Skin eruptions and liver abnormalities are less common.
- Avoid driving or operating machinery while taking chlordiazepoxide hydrochloride/clidinium bromide because it reduces mental alertness.
What is the dosage for chlordiazepoxide hydrochloride and clidinium bromide?
Chlordiazepoxide hydrochloride/clidinium bromide may be taken with or without food. Take 1 to two capsules every 6 to 8 hours before meals and at bedtime.
Which drugs or supplements interact with chlordiazepoxide hydrochloride and clidinium bromide?
Chlordiazepoxide hydrochloride/clidinium bromide should not be used in people with glaucoma or urinary retention (difficulty urinating) due to benign prostatic hypertrophy (BPH) because clidinium blocks the action of choline, increasing intraocular pressure and causing difficulty urinating. Chlordiazepoxide has sedative effects and should not be combined with alcohol or other central nervous system depressants.
Is chlordiazepoxide hydrochloride and clidinium bromide safe to take if I'm pregnant or breastfeeding?
What else should I know about chlordiazepoxide hydrochloride and clidinium bromide?
What preparations of chlordiazepoxide hydrochloride and clidinium bromide are available?
Capsules: 5mg chlordiazepoxide hydrochloride and 2.5mg clidinium bromide.
How should I keep chlordiazepoxide hydrochloride and clidinium bromide stored?
Capsules should be stored at room temperature in a tightly close container.
Chlordiazepoxide hydrochloride and clidinium bromide (Librax) is a prescription drug used as therapy for peptic ulcer disease and IBS (irritable bowel syndrome). Librax also may be useful in management of acute gastroenteritis (stomach flu). Review side effects, drug interactions, dosage, storage, and pregnancy safety information prior to taking this drug.
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Related Disease Conditions
Stomach Flu (Gastroenteritis)
Stomach flu (gastroenteritis) is a term referred used to describe a variety of gastrointestinal problems. The most common signs and symptoms of gastroenteritis are nausea, vomiting, diarrhea, and abdominal pain. The most common cause of gastroenteritis in the United States is Norovirus. Other causes of gastroenteritis include Rotavirus, Astrovirus, Adenovirus, and Sapovirus. There are bacterial causes of gastroenteritis such as Salmonella, Shigella, Campylobacter Aeromonas, E. coli, Clostridium, Vibrio, Campylobacter, and Yersinia spp. Parasites that cause gastroenteritis include Giardia, Cryptosporidium, Cyclospora, and Entamoeba. Treatment for gastroenteritis is generally home remedies such as keeping hydrated to prevent dehydration. At times, hospitalization may be necessary if dehydration occurs.
Irritable Bowel Syndrome (IBS)
Irritable bowel syndrome or IBS is a GI disorder with symptoms of constipation, abdominal pain, bloating, and gas. IBS treatment includes medications, dietary changes, and lifestyle changes.
Most people with diverticulosis have few if any symptoms at all. When people do experience signs and symptoms of diverticulosis (diverticular disease) they may include abdominal pain, abdominal cramps, diarrhea, constipation, and bloating. Diverticulitis is a condition in which diverticula in the colon rupture. The rupture results in infection in the tissues that surround the colon. Treatment methods for diverticulitis include prescription medications, and in some cases, diverticulitis surgery.
Peptic Ulcer (Stomach Ulcer)
Peptic or stomach ulcers are ulcers in the lining of the stomach, duodenum, or esophagus. Learn about symptoms, causes, diet, and treatment.
How to Get Rid of Hiccups
Hiccups are involuntary spasms of the diaphragm that may be caused by medications, certain foods, surgery, strokes, brain tumors, and noxious fumes. Get tips for curing hiccups in infants and babies.
Treatment & Diagnosis
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Medications & Supplements
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.