- Understanding COPD Slideshow
- COPD (Chronic Obstructive Pulmonary Disease) Quiz
- Energy Foods for COPD Slideshow Pictures
- What is cefuroxime, and how does it work (mechanism of action)?
- What brand names are available for cefuroxime?
- Is cefuroxime available as a generic drug?
- Do I need a prescription for cefuroxime?
- What are the side effects of cefuroxime?
- What is the dosage for cefuroxime?
- Which drugs or supplements interact with cefuroxime?
- Is cefuroxime safe to take if I'm pregnant or breastfeeding?
- What else should I know about cefuroxime?
What is cefuroxime, and how does it work (mechanism of action)?
Cefuroxime is a semisynthetic cephalosporin antibiotic, chemically similar to penicillin. Cephalosporins stop or slow the growth of bacterial cells by preventing bacteria from forming the cell wall that surrounds each cell. The cell wall protects bacteria from the external environment and keeps the contents of the cell together. Without a cell wall, bacteria are not able to survive. Cefuroxime is effective against a wide variety of bacteria, such as Staphylococcus aureus, Streptococcus pneumoniae, Haemophilus influenzae, E. coli, N. gonorrhea, and many others. The FDA approved cefuroxime in December 1987.
What are the side effects of cefuroxime?
Cefuroxime is generally well tolerated, and side effects are usually transient. Commonly reported side effects are:
Other important side effects include:
Since cefuroxime is chemically related to penicillin, patients allergic to penicillin may develop an allergic reaction (sometimes even anaphylaxis) to cefuroxime. Cefuroxime like other antibiotics can alter the colon's normal bacteria, leading to overgrowth of a bacterium called Clostridium difficile. Overgrowth of this bacterium leads to the release of toxins that contribute to the development of Clostridium difficile-associated diarrhea, which may range in severity from mild diarrhea to fatal pseudomembranous colitis.
Quick GuideCOPD Lung Symptoms, Diagnosis, Treatment
What is the dosage for cefuroxime?
Typical adult oral doses are 250 or 500 mg twice daily for 7-20 days depending on the type and severity of the infection. A single 1000 mg dose may used for uncomplicated gonorrhea. The tablets and suspension are not interchangeable.
Is cefuroxime safe to take if I'm pregnant or breastfeeding?
Cephalosporins are usually considered safe for use during pregnancy.
Cefuroxime is excreted in breast milk and may cause adverse effects in the infant. Cefuroxime is approved for pediatric patients 3 months and older.
What else should I know about cefuroxime?
What preparations of cefuroxime are available?
- Tablets: 125, 250 and 500 mg.
- Powder for Oral Suspension: 125 or 250 mg per 5 ml (teaspoon).
- Injection: 750 mg, 1.5 g and 7.5 g.
How should I keep cefuroxime stored?
- Tablets should be stored at room temperature between 15 C - 30 C (59 F - 86 F).
- The oral suspension should be stored between 2 C - 30 C (36 F - 86 F) prior to mixing and refrigerated between 2 C - 8 C (36 F - 46 F) after mixing. The suspension should be discarded after 10 days.
Reference: FDA Prescribing Information
Quick GuideCOPD Lung Symptoms, Diagnosis, Treatment
Cefuroxime (Ceftin, Zinacef) is an antibiotic prescribed for the treatment of infections of the middle ear, tonsils, throat, laryngitis, bronchitis, pneumonia, UTIs, gonorrhea, and COPD. Side effects, drug interactions, dosing, and pregnancy safety should be reviewed prior to taking this medication.
Multimedia: Slideshows, Images & Quizzes
Lyme Disease Symptoms, Rash, Treatments
Lyme disease is caused by the bacterium Borrelia burgdorferi transmitted to humans through infected deer ticks. Lyme disease...
Strep (Streptococcal) Throat Infection Quiz: Test Your Infectious Disease IQ
Take the Strep (Streptococcal) Throat Infection Quiz to learn about causes, symptoms, treatments, prevention methods, diagnosis,...
Ear Infection Quiz: Test Your Medical IQ
Is it possible to prevent ear infections? Take the Ear Infection (Otitis Media) Quiz to learn the risks, causes, symptoms and...
Picture of The Clap (Gonorrhea)
A sexually transmitted infection (STI) caused by the bacterium Neisseria gonorrhoea. See a picture of The Clap (Gonorrhea) and...
Related Disease Conditions
Urinary Tract Infections (UTIs)
A urinary tract infection (UTI) is an infection of the bladder, kidneys, ureters, or urethra. E. coli, a type of bacteria that...
Laryngitis is an inflammation of the voice box (vocal cords). The most common cause of acute laryngitis is infection, which...
Sore throats are generally described as pain or discomfort in the throat area. A sore throat may be caused by: bacterial...
Tonsillitis is a contagious infection with symptoms such as: Bad...
Pneumonia is inflammation of the lungs caused by fungi, bacteria, or viruses. Symptoms and signs include cough, fever, shortness...
Bronchitis is inflammation of the airways in the lung. Acute bronchitis is is short in duration (10 to 20 days) in comparison...
COPD (Chronic Obstructive Pulmonary Disease)
COPD or chronic obstructive pulmonary disease is a lung condition caused by smoking tobacco, exposure to secondhand smoke,...
Strep throat is a bacterial infection of the throat. Signs and symptoms of strep throat include headache, nausea,...
Ear Infection (Otitis Media)
Middle ear infection or inflammation (otitis media) is inflammation of the middle ear. There are two forms of this type of ear...
Lyme disease is a bacterial illness, which is spread by ticks when they bite the skin. Initially the disease affects the skin...
Chronic bronchitis is a cough that occurs daily with production of sputum that lasts for at least three months, two years in a...
Group A streptococcal infections are caused by group A streptococcus, a bacteria that causes a variety of health problems,...
Treatment & Diagnosis
- Strep Streptococcal Throat Infection FAQs
- Ear Infection FAQs
- Antibiotics 101
- How To Reduce Your Medication Costs
- Pharmacy Visit, How To Get The Most Out of Your Visit
- Indications for Drugs: Approved vs. Non-approved
- Generic Drugs, Are They as Good as Brand-Names?
- Drugs: Buying Prescription Drugs Online Safely
- Medication Disposal - What to Do with Old or Unusable Medication
- Dangers of Mixing Medications
- Drugs: The Most Common Medication Errors
Medications & Supplements
Prevention & Wellness
Daily Health News
Lung Disease/COPD Resources
Subscribe to MedicineNet's Allergy and Asthma Newsletter
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Top cefuroxime Related ArticlesComplete List
Adenoids and Tonsils
Tonsillitis is a contagious infection with symptoms such as:
- Bad breath
- Coughing up blood
Tonsillitis can be caused acute infection of the tonsils, and several types of bacteria or viruses (for example, strep throat or mononucleosis), chronic tonsillitis, and peritonsillar abscess. Treatment of tonsillitis and adenoids include antibiotics and other medications depending on the cause, symptom relief, and in some cases, surgery (tonsillectomy or adenoidectomy ).
Bronchitis is inflammation of the airways in the lung. Acute bronchitis is is short in duration (10 to 20 days) in comparison with chronic bronchitis, which lasts for months to years. Causes of acute bronchitis include viruses and bacteria, which means it can be contagious. Acute bronchitis caused by environmental factors such as pollution or cigarette smoke is not contagious. Common symptoms for acute bronchitis include
- nasal congestion,
- sore throat,
- muscle aches, and
Acute bronchitis in children also my include runny nose, fever, and chest pain. Treatment for acute bronchitis are OTC pain relievers, cough suppressants (although not recommended in children), and rest. Infrequently antibiotics may be prescribed to treat acute bronchitis.
COPD (Chronic Obstructive Pulmonary Disease)
COPD or chronic obstructive pulmonary disease is a lung condition caused by smoking tobacco, exposure to secondhand smoke, and/or air pollutants. Conditions that accompany COPD include:
- Chronic bronchitis
- Chronic cough
Symptoms of COPD include:
- Shortness of breath
- Chronic cough
Treatment of COPD include smoking cessation, medications, and surgery. The life expectancy of a person with COPD depends on the stage of the disease.
Middle ear infection or inflammation (otitis media) is inflammation of the middle ear. There are two forms of this type of ear infection, acute and chronic. Acute otitis media is generally short in duration, and chronic otitis media generally lasts several weeks. Seventy-five percent of children in the U.S. suffer from otitis media at some point.
Signs and symptoms in babies, toddlers, and children may:
- Be irritable and pull and tug at their ears
- Be fussy
- Have problems feeding or sleeping
- Complain about pain and fullness in the ear
- Have a fever
- A buildup of pus in the ear
- Have signs and symptoms of an upper respiratory infection
Treatment depends upon the type (chronic or acute).
Ear Infection QuizIs it possible to prevent ear infections? Take the Ear Infection (Otitis Media) Quiz to learn the risks, causes, symptoms and treatments for the common ear infection.
Laryngitis is an inflammation of the voice box (vocal cords). The most common cause of acute laryngitis is infection, which inflames the vocal cords. Symptoms may vary from degree of laryngitis and age of the person (laryngitis in infants and children is more commonly caused by croup). Common symptoms include
- a "barky" cough,
- a hoarse cough,
- runny nose,
- dry cough, and
- loss of voice.
Chronic laryngitis generally lasts more than three weeks. Causes other than infection include smoking, excess coughing, GERD, and more. Treatment depends on the cause of laryngitis.
Liver BiopsyLiver biopsy is a procedure used to remove a small piece of liver tissue for examination for signs of disease or damage to the liver. Preparation for liver biopsy includes discontinuing certain medications. The techniques used to perform liver biopsy include percutaneous liver biopsy, transvenous liver biopsy, and laparoscopic liver biopsy. Recovery from liver biopsy are generally one to two days. Certain risks are associated with liver biopsy.
Lyme Disease SlideshowLyme disease is caused by the bacterium Borrelia burgdorferi transmitted to humans through infected deer ticks. Lyme disease symptoms include a bull's-eye shaped rash. See pictures of Lyme disease rashes and ticks that carry Lyme disease.
Pneumonia FactsPneumonia is inflammation of the lungs caused by fungi, bacteria, or viruses. Symptoms and signs include cough, fever, shortness of breath, and chills. Antibiotics treat pneumonia, and the choice of the antibiotic depends upon the cause of the infection.
Sore Throat (Pharyngitis)Sore throats are generally described as pain or discomfort in the throat area. A sore throat may be caused by:
- bacterial infections,
- viral infections,
- trauma, or
- injury to the throat area.
Strep Throat QuizTake the Strep (Streptococcal) Throat Infection Quiz to learn about causes, symptoms, treatments, prevention methods, diagnosis, and complications of this common infectious disease.
Strep Throat (GAS)Strep throat is a bacterial infection of the throat. Signs and symptoms of strep throat include
- sore throat, and
Strep throat symptoms in infants and children are different than in adults. Strep throat is contagious and is generally passed from person-to-person. Treatment for strep throat symptoms include home remedies and OTC medication; however, the only cure for strep throat are antibiotics.
The Clap (Gonorrhea) PictureA sexually transmitted infection (STI) caused by the bacterium Neisseria gonorrhoea. See a picture of The Clap (Gonorrhea) and learn more about the health topic.
Urinary Tract InfectionA urinary tract infection (UTI) is an infection of the bladder, kidneys, ureters, or urethra. E. coli, a type of bacteria that lives in the bowel and near the anus, causes most UTIs. UTI symptoms include pain, abdominal pain, mild fever, urinary urgency and frequency. Treatment involves a course of antibiotics.