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- What is cefpodoxime proxetil, and how does it work (mechanism of action)?
- Is cefpodoxime proxetil available as a generic drug?
- Do I need a prescription for this drug?
- What are the uses for cefpodoxime proxetil?
- Cefpodoxime proxetil side effects
- How do I take cefpodoxime proxetil (dosage)?
- Which drug or supplement interactions occur with this drug?
- What brand names are available for cefpodoxime proxetil?
- Is this medicine safe to take if I'm pregnant or breastfeeding?
- What else should I know about this medication?
What is cefpodoxime proxetil, and how does it work (mechanism of action)?
Cefpodoxime proxetil (Vantin, Banan) is an oral antibiotic prescription drug in the cephalosporin family of antibiotics.
The cephalosporin family includes:
Cefpodoxime proxetil is converted to cefpodoxime, its active form, in the body. Like other cephalosporins, cefpodoxime stops bacteria from multiplying by preventing bacteria from forming the walls that surround them. The walls are necessary to protect bacteria from their environment and to keep the contents of the bacterial cell together; most bacteria cannot survive without a cell wall. Cefpodoxime is active against a wide spectrum of bacteria such as Staphylococcus aureus, Streptococcus pneumoniae, Streptococcus pyogenes (the cause of strep throat), Streptococcus agalactiae, Hemophilus influenzae, Moraxella catarrhalis, E. coli, Klebsiella, Proteus mirabilis, Proteus vulgaris, Providencia rettgeri, Haemophilus parainfluenzae, and Neisseria gonorrhoeae.
Do I need a prescription for this drug?
Yes, your doctor or health care professional will need to write you a prescription for this medicine.
What are the uses for cefpodoxime proxetil?
Cefpodoxime is effective for the medical treatment of these infections.
- Middle ear (otitis media)
- Throat (pharyngitis)
- Urinary tract infections
- Skin structure or skin infections caused by susceptible bacteria
Cefpodoxime proxetil side effects
Side effects include:
- Abdominal pain
- Skin rash
- Diaper rash
- Muscle pain
- Allergic reactions
- Vaginal infections
Cefpodoxime should be avoided by patients who are allergic to cephalosporin type antibiotics. Since this drug is chemically related to penicillin, some patients allergic to penicillin also may have an allergic reaction (sometimes even life-threatening anaphylaxis) to cefpodoxime.
Possible serious side effects.
Like other antibiotics, cefpodoxime may cause a condition called pseudomembranous colitis, a potentially serious bacterial infection of the colon caused by a bacterium called Clostridium difficile (C. difficile colitis). Patients who develop this type of colitis as a result of antibiotic treatment can have signs and symptoms of:
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How do I take cefpodoxime proxetil (dosage)?
- The adult dose for treating pneumonia, bronchitis, or sinusitis is 200 mg every 12 hours for 10 to 14 days depending on the type of infection.
- Gonorrhea is treated with a single 200 mg dose.
- Urinary tract infections are treated with 100 mg every 12 hours for 7 to 14 days.
- The dose for skin or skin structure infections is 400 mg every 12 hours for 70 to 14 days.
Which drug or supplement interactions occur with this drug?
- Probenecid increases the concentration of cefpodoxime in the blood. Drugs that reduce acidity in the stomach (for example, antacids, H2-blockers, proton pump inhibitors) may reduce absorption of cefpodoxime.
- Combining cefpodoxime with drugs that reduce kidney function may increase the risk of harm to the kidney.
What brand names are available for cefpodoxime proxetil?
Vantin and Banan are the brand names available for this medicine in the US.
Is this medicine safe to take if I'm pregnant or breastfeeding?
Doctors and researchers have not established if this drug is safe to take during pregnancy because there are'nt adequate studies in pregnant women. However, studies in animals suggest no important effects on the fetus.
This medication is excreted in human milk. The levels of cefpodoxime in human milk were 0, 2 and 6% of blood levels at 4 hours after a 200 mg oral dose. At 6 hours after dosing, the levels in breast milk were 0%, 9% and 16% of the concentration of cefpodoxime in blood. Women should decide whether to discontinue breastfeeding or to discontinue the drug.
What else should I know about this medication?
- Tablets and granules should be stored at room temperature, 20 C – 25 C (68 F – 77 F). After mixing the granules with water, the suspension should be stored in a refrigerator, 2 C to 8 C (36 F to 46 F). The suspension should be shaken well before using and discarded if unused after 14 days.
- This medication is available as tablets in 100 mg and 200 mg and granules for oral suspension in 50 and 100 mg/5 ml.
- The FDA approved cefpodoxime proxetil in August, 1992.
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Cefpodoxime proxetil (Vantin, Banan) is an antibiotic that is used to treat various bacterial infections such as tonsillitis, ear infections, throat infections, urinary tract infections (UTIs), bronchitis, and other infections. The antibiotic works by destroying the cell walls of bacteria.
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Sinus Infection (Sinusitis)
Sinus infection (sinusitis) is caused by allergies, infection, and chemicals or other irritants of sinuses. Signs and symptoms are headache, fever, and facial tenderness, pressure, or pain. Treatments of sinus infections are generally with antibiotics and at times, home remedies.
Staph (Staphylococcus) Infection
Staphylococcus or staph is a group of bacteria that can cause a multitude of diseases. Staph infections can cause illness directly by infection or indirectly by the toxins they produce. Symptoms and signs of a staph infection include redness, swelling, pain, and drainage of pus. Minor skin infections are treated with an antibiotic ointment, while more serious infections are treated with intravenous antibiotics.
Middle Ear Infection (Otitis Media)
Middle ear infection (otitis media) is inflammation of the middle ear. There are two forms of this type of ear infection, acute and chronic. Acute otitis media is generally short in duration, and chronic otitis media generally lasts several weeks. Babies, toddlers, and children with a middle ear infection may be irritable, pull and tug at their ears, and experience numerous other symptoms and signs. Treatment depends upon the type of ear infection.
Sore Throat Home Remedies
Natural and home remedies for sore throat symptoms and pain relief include essential oils, licorice gargles, slippery elm leaves, raw garlic, Throat Coat tea, sage, and acupuncture. Typical symptoms of a sore throat include throat pain, coughing, sneezing, fever, and swollen lymph nodes. Sore throats are caused by viral (common cold, flu, mumps), bacterial (tonsillitis, some STDs), toxins, allergens, trauma or injury, or "mechanical causes" (breathing through the mouth).
Urinary Tract Infection (UTI)
A urinary tract infection (UTI) is an infection of the bladder, kidneys, ureters, or urethra. E. coli, a type of bacteria that lives in the bowel and near the anus, causes most UTIs. UTI symptoms include pain, abdominal pain, mild fever, urinary urgency and frequency. Treatment involves a course of antibiotics.
Pneumonia is inflammation of the lungs caused by fungi, bacteria, or viruses. Symptoms and signs include cough, fever, shortness of breath, and chills. Antibiotics treat pneumonia, and the choice of the antibiotic depends upon the cause of the infection.
Sore throat (throat pain) usually is described as pain or discomfort in the throat area. A sore throat may be caused by bacterial infections, viral infections, toxins, irritants, trauma, or injury to the throat area. Common symptoms of a sore throat include a fever, cough, runny nose, hoarseness, earaches, sneezing, and body aches. Home remedies for a sore throat include warm soothing liquids and throat lozenges. OTC remedies for a sore throat include OTC pain relievers such as ibuprofen or acetaminophen. Antibiotics may be necessary for some cases of sore throat.
Laryngitis is an inflammation of the voice box (vocal cords). The most common cause of acute laryngitis is infection, which inflames the vocal cords. Symptoms may vary from degree of laryngitis and age of the person (laryngitis in infants and children is more commonly caused by croup). Common symptoms include a "barky" cough, a hoarse cough, fever, cold, runny nose, dry cough, and loss of voice. Chronic laryngitis generally lasts more than three weeks. Causes other than infection include smoking, excess coughing, GERD, and more. Treatment depends on the cause of laryngitis.
Is a Staph Infection Contagious?
A staph infection is caused by the bacteria Staphylococcus aureus. Staph can cause boils, food poisoning, cellulitis, toxic shock syndrome, MRSA, and various other illnesses and infections. Most staph infections are transmitted from person to person.
Is Pneumonia Contagious?
Pneumonia is inflammation of the lung usually caused by bacterial or viral infection (rarely, also by fungi) that causes the air sacs to fill with pus. If inflammation affects both lungs, the infection is termed double pneumonia. If it affects one lung, it is termed single pneumonia. If it affects only a certain lobe of a lung it's termed lobar pneumonia. Most pneumonias are caused by bacteria and viruses, but some pneumonias are caused by inhaling toxic chemicals that damage lung tissue.
Is Strep Throat Contagious?
Strep throat is caused by group A streptococcus bacteria. Incubation period for strep throat is 1-5 days after exposure. If strep throat is treated with antibiotics, it is no longer contagious after 24 hours; if it is not treated with antibiotics, it is contagious for 2-3 weeks. Symptoms include fever, sore throat, tonsillitis, white spots or patches on the tonsils, and nausea and vomiting. Diagnosis of strep throat is performed through a rapid strep test.
Is a Urinary Tract Infection (UTI) Contagious?
Bacteria such as E. coli or Pseudomonas can cause a urinary tract infection (UTI). The incubation period for a UTI ranges from three to eight days.
Is Laryngitis Contagious?
Laryngitis is inflammation and swelling of the voice box (larynx). Causes of laryngitis are viral, bacterial, fungal, strenuous singing or talking, chemical irritants, and other underlying medical conditions. Symptoms of laryngitis are hoarseness, a weak or loss of voice, sore throat, dry throat, a tickling sensation in the back of the throat, or irritated or raw throat. Treatment of laryngitis depends upon the cause.
Are Skin Rashes Contagious?
Direct and indirect contact can spread some types of rashes from person to person. Rash treatment depends upon a rash's underlying cause. A rash that sheds large amounts of skin warrants urgent medical attention. Rashes can be either contagious or noncontagious. Noncontagious rashes include seborrheic dermatitis, atopic dermatitis, contact dermatitis, stasis dermatitis, psoriasis, nummular eczema, drug eruptions, hives, heat rash (miliaria), and diaper rash. Rashes usually considered contagious include molluscum contagiosum (viral), impetigo (bacterial), herpes (herpes simplex, types 1 and 2 viruses), rash caused by Neisseria meningitides (N. meningitides) (bacterial), rash and blisters that accompany shingles (herpes zoster virus), ringworm (fungal) infections (tinea), scabies (itch mite), chickenpox (viral), measles and rubella (viral), erythema infectiosum (viral), pityriasis rosea (viral), cellulitis and erysipelas (bacterial), lymphangitis (bacterial, and folliculitis (bacterial).
Is a Sinus Infection Contagious?
Sinus infection (sinusitis) is infection (viral, bacterial, or fungal) or inflammation of the sinuses. Symptoms of sinus infection are cough, bad breath, coughing up greenish-yellow sputum, sinus headache, and other symptoms of the common cold. Treatments of sinus infection are home remedies to soothe symptoms and antibiotics if the infection is bacterial or fungal.
Strep throat is a bacterial infection of the throat. Signs and symptoms of strep throat include headache, nausea, vomiting, sore throat, and fever. Strep throat symptoms in infants and children are different than in adults. Strep throat is contagious and is generally passed from person-to-person. Treatment for strep throat symptoms include home remedies and OTC medication; however, the only cure for strep throat are antibiotics.
Is Sore Throat (Pharyngitis) Contagious?
The medical term for a sore throat is pharyngitis. There are many causes of a sore throat such as medications, diseases (GERD, cancer, AIDS), infections (Streptococcus or strep, mononucleosis), allergies, and smoking. Symptoms are a red, swollen throat; fever, and swollen lymph nodes. Treatment for sore throat depends on the cause.
Urinary Tract Infections in Children
Urinary tract infections (UTIs) are very common in children. Symptoms and signs include fever and abdominal pain. Associated symptoms and signs include flank pain, vomiting, and blood in the urine. Treatment for a UTI involves antibiotic therapy.
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