- Side Effects
- Drug Interactions
- Pregnancy & Breastfeeding
- What Else to Know
Generic Name: cefpodoxime proxetil
Brand Names: Vantin, Bantan
Drug Class: Cephalosporins, 3rd Generation
What is cefpodoxime proxetil, and what is it used for?
Cefpodoxime proxetil (Vantin, Banan) is an oral antibiotic prescription drug in the cephalosporin family of antibiotics.
The cephalosporin family includes:
- Cephalexin (Keflex)
- Cefaclor (Ceclor)
- Cefuroxime (Zinacef)
- Cefprozil (Cefzil)
- Many injectable forms
Cefpodoxime proxetil is converted to cefpodoxime, its active form, in the body. Like other cephalosporins, cefpodoxime stops bacteria from multiplying by preventing bacteria from forming the walls that surround them. The walls are necessary to protect bacteria from their environment and to keep the contents of the bacterial cell together; most bacteria cannot survive without a cell wall. Cefpodoxime is active against a wide spectrum of bacteria such as Staphylococcus aureus, Streptococcus pneumoniae, Streptococcus pyogenes (the cause of strep throat), Streptococcus agalactiae, Hemophilus influenzae, Moraxella catarrhalis, E. coli, Klebsiella, Proteus mirabilis, Proteus vulgaris, Providencia rettgeri, Haemophilus parainfluenzae, and Neisseria gonorrhoeae.
Cefpodoxime is effective for the medical treatment of these infections.
- Middle ear (otitis media)
- Throat (pharyngitis)
- Urinary tract infections
- Skin structure or skin infections caused by susceptible bacteria
It also is used for the treatment of gonorrhea as well as acute and chronic bronchitis (bacterial) in patients with chronic obstructive pulmonary disease (COPD).
What are the side effects of cefpodoxime proxetil?
Side effects of cefpodoxime proxetil include:
- Abdominal pain
- Skin rash
- Diaper rash
- Muscle pain
- Allergic reactions
- Vaginal infections
Cefpodoxime should be avoided by patients who are allergic to cephalosporin type antibiotics. Since this drug is chemically related to penicillin, some patients allergic to penicillin also may have an allergic reaction (sometimes even life-threatening anaphylaxis) to cefpodoxime.
Possible serious side effects.
Like other antibiotics, cefpodoxime may cause a condition called pseudomembranous colitis, a potentially serious bacterial infection of the colon caused by a bacterium called Clostridium difficile (C. difficile colitis). Patients who develop this type of colitis as a result of antibiotic treatment can have signs and symptoms of:
What is the dosage for cefpodoxime proxetil?
- The adult dose for treating pneumonia, bronchitis, or sinusitis is 200 mg every 12 hours for 10 to 14 days depending on the type of infection.
- Gonorrhea is treated with a single 200 mg dose.
- Urinary tract infections are treated with 100 mg every 12 hours for 7 to 14 days.
- The dose for skin or skin structure infections is 400 mg every 12 hours for 70 to 14 days.
Which drugs interact with cefpodoxime proxetil?
- Probenecid increases the concentration of cefpodoxime in the blood. Drugs that reduce acidity in the stomach (for example, antacids, H2-blockers, proton pump inhibitors) may reduce absorption of cefpodoxime.
- Combining cefpodoxime with drugs that reduce kidney function may increase the risk of harm to the kidney.
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Pregnancy and breastfeeding
- Doctors and researchers have not established if this drug is safe to take during pregnancy because there are'nt adequate studies in pregnant women. However, studies in animals suggest no important effects on the fetus.
- This medication is excreted in human milk. The levels of cefpodoxime in human milk were 0, 2 and 6% of blood levels at 4 hours after a 200 mg oral dose. At 6 hours after dosing, the levels in breast milk were 0%, 9% and 16% of the concentration of cefpodoxime in blood. Women should decide whether to discontinue breastfeeding or to discontinue the drug.
What else should I know about this medication?
- Tablets and granules should be stored at room temperature, 20 C – 25 C (68 F – 77 F). After mixing the granules with water, the suspension should be stored in a refrigerator, 2 C to 8 C (36 F to 46 F). The suspension should be shaken well before using and discarded if unused after 14 days.
- This medication is available as tablets in 100 mg and 200 mg and granules for oral suspension in 50 and 100 mg/5 ml.
- The FDA approved cefpodoxime proxetil in August, 1992.
Cefpodoxime proxetil is an antibiotic that is used to treat various bacterial infections such as tonsillitis, ear infections, throat infections, urinary tract infections (UTIs), bronchitis, and other infections. The antibiotic works by destroying the cell walls of bacteria. Side effects of cefpodoxime proxetil include diarrhea, nausea, abdominal pain, vomiting, skin rash, diaper rash, fever, muscle pain, allergic reactions, vaginitis, vaginal infections, itching, headaches, dizziness, and insomnia. Cefpodoxime may cause a condition called pseudomembranous colitis, a potentially serious bacterial infection of the colon caused by a bacterium called Clostridium difficile (C. difficile colitis).
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Related Disease Conditions
Sinus Infection (Sinusitis)
Sinus infection (sinusitis) is caused by allergies, infection, and chemicals or other irritants of sinuses. Signs and symptoms include headache, fever, and facial tenderness, pressure, or pain. Treatments of sinus infections are generally with antibiotics and at times, home remedies.
Laryngitis is an inflammation of the voice box (vocal cords). The most common cause of acute laryngitis is an infection, which inflames the vocal cords. Symptoms may vary from the degree of laryngitis and age of the person (laryngitis in infants and children is more commonly caused by croup).
Inner Ear Infection
An inner ear infection or otitis interna is caused by viruses or bacteria and can occur in both adults and children. An inner ear infection can cause symptoms and signs, for example, a severe ear, dizziness, vertigo, nausea and vomiting, and vertigo. An inner ear infection also may cause inflammation of the inner ear or labyrinthitis. Inner ear infections are not contagious; however, the bacteria and viruses that cause the infection can be transmitted to other people. Good hygiene practices will help decrease the chances of the infection spreading to others. Inner ear infection symptoms and signs like ear pain and nausea may be relieved with home remedies or over-the-counter (OTC) medication. Some inner ear infections will need to be treated and cured with antibiotics or prescription pain or antinausea medication.
Urinary Tract Infection (UTI)
A urinary tract infection (UTI) is an infection of the bladder, kidneys, ureters, or urethra. E. coli, a type of bacteria that lives in the bowel and near the anus, causes most UTIs. UTI symptoms include pain, abdominal pain, mild fever, urinary urgency, and frequency. Treatment involves a course of antibiotics.
Sore Throat Home Remedies
Natural and home remedies for sore throat symptoms and pain relief include essential oils, licorice gargles, slippery elm leaves, raw garlic, Throat Coat tea, sage, and acupuncture. Typical symptoms of a sore throat include throat pain, coughing, sneezing, fever, and swollen lymph nodes. Sore throats are caused by viral (common cold, flu, mumps), bacterial (tonsillitis, some STDs), toxins, allergens, trauma or injury, or "mechanical causes" (breathing through the mouth).
Middle Ear Infection (Otitis Media)
A middle ear infection (otitis media) can cause earache, temporary hearing loss, and pus drainage from the ear. It is most common in babies, toddlers, and young children. Learn about causes and treatment.
Sore throat (throat pain) usually is described as pain or discomfort in the throat area. A sore throat may be caused by bacterial infections, viral infections, toxins, irritants, trauma, or injury to the throat area. Common symptoms of a sore throat include a fever, cough, runny nose, hoarseness, earaches, sneezing, and body aches. Home remedies for a sore throat include warm soothing liquids and throat lozenges. OTC remedies for a sore throat include OTC pain relievers such as ibuprofen or acetaminophen. Antibiotics may be necessary for some cases of sore throat.
Tonsillitis is a contagious infection with symptoms of bad breath, snoring, congestion, headache, hoarseness, laryngitis, and coughing up blood. Tonsillitis can be caused by acute infection of the tonsils, and several types of bacteria or viruses (for example, strep throat or mononucleosis). There are two types of tonsillitis, acute and chronic. Acute tonsillitis lasts from 1-2 weeks while chronic tonsillitis can last from months to years. Treatment of tonsillitis and adenoids include antibiotics, over-the-counter medications, and home remedies to relieve pain and inflammation, for example, saltwater gargle, slippery elm throat lozenges, sipping warm beverages and eating frozen foods (ice cream, popsicles), serrapeptase, papain, and andrographism Some people with chronic tonsillitis may need surgery (tonsillectomy or adenoidectomy).
Is Strep Throat Contagious?
Strep throat is caused by group A streptococcus bacteria. Incubation period for strep throat is 1-5 days after exposure. If strep throat is treated with antibiotics, it is no longer contagious after 24 hours; if it is not treated with antibiotics, it is contagious for 2-3 weeks. Symptoms include fever, sore throat, tonsillitis, white spots or patches on the tonsils, and nausea and vomiting. Diagnosis of strep throat is performed through a rapid strep test.
Strep throat is a bacterial infection of the throat. Signs and symptoms of strep throat include headache, nausea, vomiting, sore throat, and fever. Strep throat symptoms in infants and children are different than in adults. Strep throat is contagious and is generally passed from person to person. Treatment for strep throat symptoms includes home remedies and OTC medication; however, the only cure for strep throat is antibiotics.
Inner Ear Infection (Labyrinthitis)
Labyrinthitis occurs when there is inflammation of the part of the ear responsible for balance and hearing), usually due to viral infections of the inner ear. Learn about causes, symptoms, and treatment.
Ear Infection Home Treatment
Infections of the outer, middle, and inner ear usually are caused by viruses. Most outer (swimmer's ear) and middle ear (otitis media) infections can be treated at home with remedies like warm compresses for ear pain relief, tea tree, ginger, or garlic oil drops. Symptoms of an outer ear (swimmer's ear) and middle ear infection include mild to severe ear pain, pus draining from the ear, swelling and redness in the ear, and hearing problems. Middle and inner ear infections may cause fever, and balance problems. Inner ear infections also may cause nausea, vomiting, vertigo, ringing in the ear, and labyrinthitis (inflammation of the inner ear). Most outer and middle ear infections do not need antibiotics. Inner ear infections should be treated by a doctor specializing in ear and hearing problems.
Staph (Staphylococcus) Infection
Staphylococcus or staph is a group of bacteria that can cause a multitude of diseases. Staph infections can cause illness directly by infection or indirectly by the toxins they produce. Symptoms and signs of a staph infection include redness, swelling, pain, and drainage of pus. Minor skin infections are treated with an antibiotic ointment, while more serious infections are treated with intravenous antibiotics.
Pneumonia is inflammation of the lungs caused by fungi, bacteria, or viruses. Symptoms and signs include cough, fever, shortness of breath, and chills. Antibiotics treat pneumonia, and the choice of the antibiotic depends upon the cause of the infection.
Is Pneumonia Contagious?
Pneumonia is inflammation of the lung usually caused by bacterial or viral infection (rarely, also by fungi) that causes the air sacs to fill with pus. If inflammation affects both lungs, the infection is termed double pneumonia. If it affects one lung, it is termed single pneumonia. If it affects only a certain lobe of a lung it's termed lobar pneumonia. Most pneumonias are caused by bacteria and viruses, but some pneumonias are caused by inhaling toxic chemicals that damage lung tissue.
Is Tonsillitis Contagious?
Tonsillitis is a common infection, especially in kids. Tonsillitis is caused by viruses and bacteria like the flu and herpes simplex virus, and Streptococcus bacteria. These viruses and bacterium are spread person to person. Symptoms of tonsillitis are a yellow or white coating on the tonsils, throat pain, pain when swallowing, and hoarseness.
Is a Urinary Tract Infection (UTI) Contagious?
Bacteria such as E. coli or Pseudomonas can cause a urinary tract infection (UTI). The incubation period for a UTI ranges from three to eight days.
Bladder Infection (Cystitis)
Bladder infection is an infection of the bladder, usually caused by bacteria or, rarely, by Candida. Certain people, including females, the elderly, men with enlarged prostates, and those with chronic medical conditions are at increased risk for bladder infection. Bladder infections are treated with antibiotics, but cranberry products and adequate hydration may help prevent bladder infections.
Is Sore Throat (Pharyngitis) Contagious?
Pharyngitis is a contagious infection that can spread from one person to another. Depending on the cause of your sore throat, you may be more or less contagious. Evaluation from a healthcare provider can help diagnose the cause of your sore throat.
Is Laryngitis Contagious?
Laryngitis is inflammation and swelling of the voice box (larynx). Causes of laryngitis are viral, bacterial, fungal, strenuous singing or talking, chemical irritants, and other underlying medical conditions. Symptoms of laryngitis are hoarseness, a weak or loss of voice, sore throat, dry throat, a tickling sensation in the back of the throat, or irritated or raw throat. Treatment of laryngitis depends upon the cause.
Is a Staph Infection Contagious?
A staph infection is caused by the bacteria Staphylococcus aureus. Staph can cause boils, food poisoning, cellulitis, toxic shock syndrome, MRSA, and various other illnesses and infections. Most staph infections are transmitted from person to person.
Is a Sinus Infection Contagious?
Sinus infection (sinusitis) is an infection (viral, bacterial, or fungal) or inflammation of the sinuses. Symptoms of sinus infection are cough, bad breath, coughing up greenish-yellow sputum, sinus headache, and other symptoms of the common cold. Treatments of sinus infection are home remedies to soothe symptoms and antibiotics if the infection is bacterial or fungal.
How Do You Get Rid of an Inner Ear Infection Without Antibiotics?
What Is an Inner Ear Infection? Learn whether you need antibiotics and what other treatments can help to relieve your symptoms.
Are Skin Rashes Contagious?
Direct and indirect contact can spread some types of rashes from person to person. Rash treatment depends upon a rash's underlying cause. A rash that sheds large amounts of skin warrants urgent medical attention. Rashes can be either contagious or noncontagious. Noncontagious rashes include seborrheic dermatitis, atopic dermatitis, contact dermatitis, stasis dermatitis, psoriasis, nummular eczema, drug eruptions, hives, heat rash (miliaria), and diaper rash. Rashes usually considered contagious include molluscum contagiosum (viral), impetigo (bacterial), herpes (herpes simplex, types 1 and 2 viruses), rash caused by Neisseria meningitides (N. meningitides) (bacterial), rash and blisters that accompany shingles (herpes zoster virus), ringworm (fungal) infections (tinea), scabies (itch mite), chickenpox (viral), measles and rubella (viral), erythema infectiosum (viral), pityriasis rosea (viral), cellulitis and erysipelas (bacterial), lymphangitis (bacterial, and folliculitis (bacterial).
Will Tonsillitis Go Away on Its Own?
Tonsils are the two oval-shaped pads of tissue in the back of your throat. They help protect your body from infection. However, sometimes they get infected and inflamed (red and swollen) and this is called tonsillitis. Tonsillitis symptoms usually go away after three to four days.
How Do You Know if Your Baby Has an Ear Infection?
Baby ear infection symptoms can include signs of irritability, tugging on the ears, an unpleasant smell and discharge coming from the ears, and more. Learn all the signs here.
How Long Does Dizziness Last With an Inner Ear Infection?
If an infection occurs in any part of your inner ear, irritation can occur and lead to inflammation. Dizziness due to an ear infection usually goes away within a few weeks.
Urinary Tract Infections in Children
Urinary tract infections (UTIs) are very common in children. Symptoms and signs include fever and abdominal pain. Associated symptoms and signs include flank pain, vomiting, and blood in the urine. Treatment for a UTI involves antibiotic therapy.
How Long Does Vertigo Last From Inner Ear Infection?
The symptoms of vertigo from inner ear infections may last for many days and manifest themselves severely. After about one to two weeks, they often go away.
Yeast Infection vs. Urinary Tract Infection (UTI)
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How Long Does Vertigo Last From an Inner Ear Infection?
Vertigo is a feeling of dizziness or the sensation that the room around you is spinning. An inner ear infection can cause vertigo for a few hours, days, or weeks.
How Do You Know If You Have Vertigo or Ear Infection?
The sensation that the world around you is spinning is called vertigo while infection of the inner ear may cause labyrinthitis. The type of vertigo that is associated with an inner ear infection is called peripheral vertigo.
What Is the Best Treatment for Urinary Tract Infection?
In most cases, the best treatment for a urinary tract infection (UTI) is a course of antibiotics. Which antibiotics are prescribed depend on the type of bacteria responsible.
Home Remedies for Tonsillitis: Treatment and Relief
Tonsillitis usually runs its course. Home remedies may help ease your/your child’s symptoms including getting plenty of rest, gargling, drinking water, washing your hands and taking over-the-counter pain relieving medication.
How Do You Know If You Have Tonsillitis?
What is tonsillitis, and how do you know if you have it? Learn the signs of tonsillitis and what to do if you have it.
What Is the Most Common Cause of Urinary Tract Infection?
E. coli bacteria are the most common cause of urinary tract infection (UTI).
How Does a Woman Get a Urinary Tract Infection?
Urinary tract infections (UTIs) occur more frequently in women because they have a shorter urethra, making it easier for bacteria from the anus to travel to the area.
Urinary Tract Infection or Urinary Infection
The urinary system of your body includes two kidneys, two tubes (ureters), a urine sac (bladder) and an opening to expel the urine from the body (urethra). An infection of this system due to germs is called a urinary tract infection (UTI). UTI may be treated with antibiotics, especially if a kidney infection is involved.
Bladder Infection in Adults
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How Do You Know if You Have a Urinary Tract Infection?
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How Do You Get Rid of a Urinary Tract Infection (UTI)?
Learn what medical treatments can help treat your urinary tract infection symptoms and help you manage this condition.
What Causes a Urinary Tract Infection in a Child?
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