- Side Effects
- Drug Interaction
- Precautions & Warnings
- Things to Know
Brand Name: Suprax
Generic Name: cefixime
Drug Class: Cephalosporins, 3rd Generation
What is cefixime, and how does it work (mechanism of action)?
Cefixime is a semi-synthetic (partially man-made), oral antibiotic in the cephalosporin family of antibiotics. The cephalosporin family includes cephalexin (Keflex), cefaclor (Ceclor), cefuroxime (Zinacef), cefpodoxime (Vantin), cefprozil (Cefzil), and many injectable forms. Like other cephalosporins, cefixime stops bacteria from multiplying by preventing bacteria from forming the walls that surround them. The walls are necessary to protect bacteria from their environment and to keep the contents of the bacterial cell together; most bacteria cannot survive without a cell wall.
Cefixime is active against a very wide spectrum of bacteria such as:
- Staphylococcus aureus
- Streptococcus pneumoniae
- Streptococcus pyogenes (the cause of strep throat)
- Hemophilus influenzae
- Moraxella catarrhalis
- E. coli
- Proteus mirabilis
- Neisseria gonorrhoeae
The FDA approved cefixime in April 1989.
What brand names are available for a cefixime?
Is cefixime available as a generic drug?
Do I need a prescription for a cefixime?
What are the uses for cefixime?
Cefixime is effective for infections like:
- infection of the middle ear (otitis media),
- throat infections (pharyngitis),
- bronchitis, and
- pneumonia caused by susceptible bacteria.
It also is used for treating:
- urinary tract infections,
- gonorrhea, and
- acute bacterial bronchitis in patients with chronic obstructive pulmonary disease (COPD).
What are the side effects of cefixime?
Common side effects of cefixime include:
- abdominal pain,
- vomiting and,
- skin rash.
Other side effects include:
What is the dosage for cefixime?
The recommended adult dose for otitis media, tonsillitis, pharyngitis, and urinary tract infections is 400 mg once daily or divided and given as 200 mg every 12 hours. Pediatric patients (6 months and older) have a recommended dose of 8 mg/kg/day once daily or in two doses of 4/mg/kg every 12 hours.
Which drugs or supplements interact with cefixime?
Probenecid (Benemid) may increase the blood concentration of cefixime by decreasing the removal of cefixime by the kidney. This interaction sometimes is used to enhance the effect of cephalosporins.
Combining cefixime with aminoglycosides (for example, tobramycin [Tobradex] produces additive bacterial killing effects but also may increase the risk of harmful effects to the kidney.)
Exenatide (Byetta) may delay or reduce the absorption of cephalosporins. Cephalosporins should be administered one hour before exenatide.
Cefixime may cause a false positive urine ketone test.
Is cefixime safe to take if I'm pregnant or breastfeeding?
Safety in pregnancy has not been established for cefixime. There are no adequate studies on pregnant women; however, studies in animals suggest no important effects on the fetus.
Safety in nursing mothers has not been established. It is not known if cefixime is excreted in breast milk.
What else should I know about cefixime?
Tablets: 400 mg. Tablet (Chewable): 100, 200 mg. Suspension: 100,200, 500 mg/5 ml.How should I keep cefixime stored?
Tablets and oral suspension may be stored at room temperature, 20 C to 25 C (68 F to 77 F), in a tightly closed container. Suspension may be refrigerated or stored at room temperature after mixing.
- Chinese Company May Help Ease U.S. Shortage of Cancer Drug
- Opdivo Could Boost Outcomes for People Battling Hodgkin Lymphoma
- More U.S. Kids, Teens Are Getting Weight-Loss Surgeries
- Could a Nitroglycerin Patch Ease Hot Flashes?
- One Form of Menopause Hormone Therapy Might Raise Blood Pressure
- More Health News »
Cefixime (Suprax) is an antibiotic in the cephalosporin class of drugs. Cefixime (Suprax) is prescribed for the treatment of bacterial infections. Review side effects, drug interactions, warnings and precautions, and patient information prior to taking any medication.
Multimedia: Slideshows, Images & Quizzes
What Is a Staph Infection? Causes, Symptoms, Treatments
Do you know what a staph infection is? What about golden staph? Learn about the causes, symptoms, and treatments of staph...
What happens within the body when a person develops bronchitis? Take this quick quiz to learn the causes, symptoms, treatments,...
Ear Infection Quiz: Test Your Medical IQ
Is it possible to prevent ear infections? Take the Ear Infection (Otitis Media) Quiz to learn the risks, causes, symptoms and...
Strep (Streptococcal) Throat Infection Quiz: Test Your Infectious Disease IQ
Take the Strep (Streptococcal) Throat Infection Quiz to learn about causes, symptoms, treatments, prevention methods, diagnosis,...
Urinary Tract Infection Quiz
How would you know if you had urinary tract infection (UTI)? Take the Urinary Tract Infection in Adult Quiz to learn the causes,...
Picture of The Clap (Gonorrhea)
A sexually transmitted infection (STI) caused by the bacterium Neisseria gonorrhoea. See a picture of The Clap (Gonorrhea) and...
Related Disease Conditions
STDs in Men
Symptoms of sexually transmitted diseases (STDs) in men include painful urination, bumps or sores on the penis, and penile discharge and itching. Learn about the most common STDs in men.
Urinary Tract Infection (UTI)
A urinary tract infection (UTI) is an infection of the bladder, kidneys, ureters, or urethra. E. coli, a type of bacteria that lives in the bowel and near the anus, causes most UTIs. UTI symptoms include pain, abdominal pain, mild fever, urinary urgency, and frequency. Treatment involves a course of antibiotics.
Laryngitis is an inflammation of the voice box (vocal cords). The most common cause of acute laryngitis is an infection, which inflames the vocal cords. Symptoms may vary from the degree of laryngitis and age of the person (laryngitis in infants and children is more commonly caused by croup).
Middle Ear Infection (Otitis Media)
A middle ear infection (otitis media) can cause earache, temporary hearing loss, and pus drainage from the ear. It is most common in babies, toddlers, and young children. Learn about causes and treatment.
Tonsillitis is a contagious infection with symptoms of bad breath, snoring, congestion, headache, hoarseness, laryngitis, and coughing up blood. Tonsillitis can be caused by acute infection of the tonsils, and several types of bacteria or viruses (for example, strep throat or mononucleosis). There are two types of tonsillitis, acute and chronic. Acute tonsillitis lasts from 1-2 weeks while chronic tonsillitis can last from months to years. Treatment of tonsillitis and adenoids include antibiotics, over-the-counter medications, and home remedies to relieve pain and inflammation, for example, saltwater gargle, slippery elm throat lozenges, sipping warm beverages and eating frozen foods (ice cream, popsicles), serrapeptase, papain, and andrographism Some people with chronic tonsillitis may need surgery (tonsillectomy or adenoidectomy).
Sore throat (throat pain) usually is described as pain or discomfort in the throat area. A sore throat may be caused by bacterial infections, viral infections, toxins, irritants, trauma, or injury to the throat area. Common symptoms of a sore throat include a fever, cough, runny nose, hoarseness, earaches, sneezing, and body aches. Home remedies for a sore throat include warm soothing liquids and throat lozenges. OTC remedies for a sore throat include OTC pain relievers such as ibuprofen or acetaminophen. Antibiotics may be necessary for some cases of sore throat.
Strep throat is a bacterial infection of the throat. Signs and symptoms of strep throat include headache, nausea, vomiting, sore throat, and fever. Strep throat symptoms in infants and children are different than in adults. Strep throat is contagious and is generally passed from person to person. Treatment for strep throat symptoms includes home remedies and OTC medication; however, the only cure for strep throat is antibiotics.
Staph (Staphylococcus) Infection
Staphylococcus or staph is a group of bacteria that can cause a multitude of diseases. Staph infections can cause illness directly by infection or indirectly by the toxins they produce. Symptoms and signs of a staph infection include redness, swelling, pain, and drainage of pus. Minor skin infections are treated with an antibiotic ointment, while more serious infections are treated with intravenous antibiotics.
Gonorrhea In Women
Gonorrhea is a bacterial infection transmitted during sexual contact. In women, symptoms include a yellow vaginal discharge, burning or frequent urination, and redness, swelling, burning, and itching of the vaginal area. Gonorrhea can be treated with injectable (penicillin) or oral medications.
Sexually Transmitted Diseases (STDs)
Common sexually transmitted diseases (STDs) in women include gonorrhea, chlamydia, genital herpes, and HPV infection (genital warts). Learn about types, symptoms, and treatment.
Pneumonia is inflammation of the lungs caused by fungi, bacteria, or viruses. Symptoms and signs include cough, fever, shortness of breath, and chills. Antibiotics treat pneumonia, and the choice of the antibiotic depends upon the cause of the infection.
Bronchitis is inflammation of the airways in the lung. Acute bronchitis is short in duration (10-20 days) in comparison with chronic bronchitis, which lasts for months to years. Causes of acute bronchitis include viruses and bacteria, which means it can be contagious. Acute bronchitis caused by environmental factors such as pollution or cigarette smoke is not contagious. Common symptoms for acute bronchitis include nasal congestion, cough, headache, sore throat, muscle aches, and fatigue. Acute bronchitis in children also my include runny nose, fever, and chest pain. Treatment for acute bronchitis are OTC pain relievers, cough suppressants (although not recommended in children), and rest. Infrequently antibiotics may be prescribed to treat acute bronchitis.
COPD (Chronic Obstructive Pulmonary Disease)
COPD or chronic obstructive pulmonary disease is a lung condition caused by smoking tobacco, exposure to secondhand smoke, and/or air pollutants. Conditions that accompany COPD include chronic bronchitis, chronic cough, and emphysema. Symptoms of COPD include shortness of breath, wheezing, and chronic cough. Treatment of COPD includes GOLD guidelines, smoking cessation, medications, and surgery. The life expectancy of a person with COPD depends on the stage of the disease.
Antibiotic Resistance (Drug Resistance, Antimicrobial Resistance)
Antibiotics are medications used to kill or slow the growth of bacteria and some fungi. The definition of antibiotic resistance is the ability of bacteria to change (mutate) and grow in the presence of a drug (an antibiotic) that would normally slow its growth or kill it. These antibiotic-resistant bacteria and fungi become harder to treat. Antibiotic-resistant infections can lead to longer hospital stays, higher treatment costs, and more deaths.
Treatment & Diagnosis
- Urinary Tract Infection FAQs
- Strep Streptococcal Throat Infection FAQs
- Ear Infection FAQs
- Bronchitis FAQs
- Drugs: Buying Prescription Drugs Online Safely
- How To Reduce Your Medication Costs
- Pharmacy Visit, How To Get The Most Out of Your Visit
- Indications for Drugs: Approved vs. Non-approved
- Drugs: The Most Common Medication Errors
- Gonorrhea Treatment Recommendations Update
- Medication Disposal
- Dangers of Mixing Medications
- Antibiotics 101
- Generic Drugs, Are They as Good as Brand-Names?
Medications & Supplements
Health Solutions From Our Sponsors
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
FDA Prescribing Information