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- What is cefixime, and how does it work (mechanism of action)?
- What brand names are available for cefixime?
- Is cefixime available as a generic drug?
- Do I need a prescription for cefixime?
- What are the uses for cefixime?
- What are the side effects of cefixime?
- What is the dosage for cefixime?
- Which drugs or supplements interact with cefixime?
- Is cefixime safe to take if I'm pregnant or breastfeeding?
- What else should I know about cefixime?
What is cefixime, and how does it work (mechanism of action)?
Cefixime is a semi-synthetic (partially man-made), oral antibiotic in the cephalosporin family of antibiotics. The cephalosporin family includes cephalexin (Keflex), cefaclor (Ceclor), cefuroxime (Zinacef), cefpodoxime (Vantin), cefprozil (Cefzil), and many injectable forms. Like other cephalosporins, cefixime stops bacteria from multiplying by preventing bacteria from forming the walls that surround them. The walls are necessary to protect bacteria from their environment and to keep the contents of the bacterial cell together; most bacteria cannot survive without a cell wall. Cefixime is active against a very wide spectrum of bacteria such as Staphylococcus aureus, Streptococcus pneumoniae, Streptococcus pyogenes (the cause of strep throat), Hemophilus influenzae, Moraxella catarrhalis, E. coli, Klebsiella, Proteus mirabilis, Salmonella, Shigella, and Neisseria gonorrhoeae. The FDA approved cefixime in April 1989.
What are the uses for cefixime?
Cefixime is effective for infections like:
- infection of the middle ear (otitis media),
- throat infections (pharyngitis),
- bronchitis, and
- pneumonia caused by susceptible bacteria.
It also is used for treating
What are the side effects of cefixime?
Common side effects of cefixime include:
Other side effects include:
Quick GuideSymptoms of Mono: Infectious Mononucleosis Treatment
What is the dosage for cefixime?
The recommended adult dose for otitis media, tonsillitis, pharyngitis, and urinary tract infections is 400 mg once daily or divided and given as 200 mg every 12 hours. Pediatric patients (6 months and older) have a recommended dose of 8 mg/kg/day once daily or in two doses of 4/mg/kg every 12 hours.
Which drugs or supplements interact with cefixime?
Combining cefixime with aminoglycosides (for example, tobramycin [Tobradex] produces additive bacterial killing effects but also may increase the risk of harmful effects to the kidney.)
Cefixime may cause a false positive urine ketone test.
Is cefixime safe to take if I'm pregnant or breastfeeding?
Safety in pregnancy has not been established for cefixime. There are no adequate studies in pregnant women; however, studies in animals suggest no important effects on the fetus.
Safety in nursing mothers has not been established. It is not known if cefixime is excreted in breast milk.
What else should I know about cefixime?
What preparations of cefixime are available?
Tablets: 400 mg. Tablet (Chewable): 100, 200 mg. Suspension: 100,200, 500 mg/5 ml.
How should I keep cefixime stored?
Tablets and oral suspension may be stored at room temperature, 20 C to 25 C (68 F to 77 F), in a tightly closed container. Suspension may be refrigerated or stored at room temperature after mixing.
REFERENCE: FDA Prescribing Information
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Top cefixime Related ArticlesComplete List
Adenoids and Tonsils
Tonsillitis is a contagious infection with symptoms such as:
- Bad breath
- Coughing up blood
Tonsillitis can be caused acute infection of the tonsils, and several types of bacteria or viruses (for example, strep throat or mononucleosis), chronic tonsillitis, and peritonsillar abscess. Treatment of tonsillitis and adenoids include antibiotics and other medications depending on the cause, symptom relief, and in some cases, surgery (tonsillectomy or adenoidectomy ).
COPD (Chronic Obstructive Pulmonary Disease)
COPD or chronic obstructive pulmonary disease is a lung condition caused by smoking tobacco, exposure to secondhand smoke, and/or air pollutants. Conditions that accompany COPD include:
- Chronic bronchitis
- Chronic cough
Symptoms of COPD include:
- Shortness of breath
- Chronic cough
Treatment of COPD include smoking cessation, medications, and surgery. The life expectancy of a person with COPD depends on the stage of the disease.
Middle ear infection or inflammation (otitis media) is inflammation of the middle ear. There are two forms of this type of ear infection, acute and chronic. Acute otitis media is generally short in duration, and chronic otitis media generally lasts several weeks. Seventy-five percent of children in the U.S. suffer from otitis media at some point.
Signs and symptoms in babies, toddlers, and children may:
- Be irritable and pull and tug at their ears
- Be fussy
- Have problems feeding or sleeping
- Complain about pain and fullness in the ear
- Have a fever
- A buildup of pus in the ear
- Have signs and symptoms of an upper respiratory infection
Treatment depends upon the type (chronic or acute).
Ear Infection QuizIs it possible to prevent ear infections? Take the Ear Infection (Otitis Media) Quiz to learn the risks, causes, symptoms and treatments for the common ear infection.
Gonorrhea In WomenGonorrhea is a bacterial infection transmitted during sexual contact. In women, symptoms include a yellow vaginal discharge, burning or frequent urination, and redness, swelling, burning and itching of the vaginal area. Gonorrhea can be treated with injectable (penicillin) or oral medications.
Pneumonia FactsPneumonia is inflammation of the lungs caused by fungi, bacteria, or viruses. Symptoms and signs include cough, fever, shortness of breath, and chills. Antibiotics treat pneumonia, and the choice of the antibiotic depends upon the cause of the infection.
Sexually Transmitted Diseases (STDs In Women)
Sexually transmitted diseases, or STDs, are infections that are transmitted during any type of sexual exposure, including intercourse (vaginal or anal), oral sex, and the sharing of sexual devices, such as vibrators. Women can contract all of the STDs, but may have no symptoms, or have different symptoms than men do. Common STDs in women are:
- Zika virus
- Genital herpes
- Hepatitis B
- Hepatitis C
- Pubic lice
- Genital warts
Treatment for STDs depends upon the type.
Sore Throat (Pharyngitis)Sore throats are generally described as pain or discomfort in the throat area. A sore throat may be caused by:
- bacterial infections,
- viral infections,
- trauma, or
- injury to the throat area.
Staph InfectionStaphylococcus or Staph is a group of bacteria that can cause a multitude of diseases. Staph infections can cause illness directly by infection or indirectly by the toxins they produce. Symptoms and signs of a Staph infection include redness, swelling, pain, and drainage of pus. Minor skin infections are treated with an antibiotic ointment, while more serious infections are treated with intravenous antibiotics.
Staph Infection SlideshowDo you know what a staph infection is? Learn about the causes, symptoms, and treatment of staph infections (Staphylococcus aureus), and how this group of bacteria can cause a multitude diseases ranging from mild to potentially fatal.
Strep Throat QuizTake the Strep (Streptococcal) Throat Infection Quiz to learn about causes, symptoms, treatments, prevention methods, diagnosis, and complications of this common infectious disease.
Strep Throat (GAS)Strep throat is a bacterial infection of the throat. Signs and symptoms of strep throat include
- sore throat, and
Strep throat symptoms in infants and children are different than in adults. Strep throat is contagious and is generally passed from person-to-person. Treatment for strep throat symptoms include home remedies and OTC medication; however, the only cure for strep throat are antibiotics.
The Clap (Gonorrhea) PictureA sexually transmitted infection (STI) caused by the bacterium Neisseria gonorrhoea. See a picture of The Clap (Gonorrhea) and learn more about the health topic.
Urinary Tract InfectionA urinary tract infection (UTI) is an infection of the bladder, kidneys, ureters, or urethra. E. coli, a type of bacteria that lives in the bowel and near the anus, causes most UTIs. UTI symptoms include pain, abdominal pain, mild fever, urinary urgency and frequency. Treatment involves a course of antibiotics.
Urinary Tract Infection QuizHow would you know if you had urinary tract infection (UTI)? Take the Urinary Tract Infection in Adult Quiz to learn the causes, symptoms, and treatments for infection that can affect your kidneys, ureters, bladder, and urethra.