- Bacterial Infections 101 Pictures Slideshow
- Take the Tummy Trouble Quiz
- Hepatitis C Slideshow Pictures
- What's the Difference Between Cefdinir and Amoxicillin?
- What Are Cefdinir and Amoxicillin?
- What Are the Side Effects of Cefdinir and Amoxicillin?
- What Is the Dosage of Cefdinir vs. Amoxicillin
- What Drugs Interact with Cefdinir and Amoxicillin?
- Are Cefdinir and Amoxicillin Safe to Take While Pregnant or Breastfeeding?
What's the Difference Between Cefdinir and Amoxicillin?
- Cefdinir and amoxicillin are antibiotics used to treat bacterial infections.
- The drugs are in different classes. Cefdinir is a cephalosporin antibiotic and amoxicillin is a penicillin-type antibiotic.
- Cefdinir is only available as a generic. The Omnicef brand has been discontinued and there are no other brand names available for cefdinir available in the U.S. Brand names for amoxicillin include Amoxil, Moxatag, and Larotid.
- Side effects of cefdinir and amoxicillin that are similar include diarrhea, nausea, abdominal pain, vomiting, and rash.
- Side effects of cefdinir that are different from amoxicillin include vaginal yeast infection, vaginitis, and headache.
- Side effects of amoxicillin that are different from cefdinir include dizziness, heartburn, insomnia, itching, confusion, easy bruising, bleeding, and allergic reactions.
What Are Cefdinir and Amoxicillin?
Amoxicillin belongs to a class of antibiotics called penicillins. Other members of this class include ampicillin (Unasyn), piperacillin (Pipracil), and ticarcillin (Ticar). These antibiotics all have a similar mechanism of action. They do not directly kill bacteria, but they stop bacteria from multiplying by preventing bacteria from forming the walls that surround them. The walls are necessary to protect bacteria from their environment and to keep the contents of the bacterial cell together. Bacteria cannot survive without a cell wall. Amoxicillin is effective against many different bacteria including H. influenzae, N. gonorrhoea, E. coli, Pneumococci, Streptococci, and certain strains of Staphylococci.
What Are the Side Effects of Cefdinir and Amoxicillin?
Cefdinir generally is well tolerated. The most common side effects are:
Rare side effects include:
Cefdinir may cause false test results with some tests for sugar in the urine.
Like most antibiotics, cefdinir may cause a condition called pseudomembranous colitis (Clostridium difficile colitis), a potentially serious bacterial infection of the colon.
Persons who are allergic to the penicillin class of antibiotics, for example, amoxicillin, amoxicillin and clavulanic acid (Augmentin), which are related to cephalosporins, may or may not be allergic to cephalosporins.
Side effects due to amoxicillin include:
- abdominal pain,
- easy bruising,
- rash, and
- allergic reactions.
People who are allergic to the cephalosporin class of antibiotics, which are related to the penicillins, for example, cefaclor (Ceclor), cephalexin (Keflex), and cefprozil (Cefzil), may or may not be allergic to penicillins.
Serious but rare reactions include:
- severe allergic reactions (anaphylaxis), and
- low platelet (thrombocytopenia) or red blood cell count.
Amoxicillin can alter the normal bacteria in the colon and encourage overgrowth of some bacteria such as Clostridium difficile which causes inflammation of the colon (pseudomembranous colitis). Patients who develop signs of pseudomembranous colitis after starting amoxicillin (diarrhea, fever, abdominal pain, and possibly shock) should contact their physician immediately.
What Is the Dosage of Cefdinir vs. Amoxicillin
- Cefdinir is taken once or twice daily, depending on the type and severity of the infection.
- The capsules or suspension can be taken with or without food.
- Patients with advanced kidney disease may need to take lower doses to prevent accumulation of cefdinir since it is eliminated from the body by the kidneys.
- For adult infections the usual dose is 300 mg every 12 hours or 600 mg per day for 5-10 days depending on the nature and severity of the infection.
- The recommended dose for children 6 months to 12 years of age is 7 mg/kg every 12 hours or 14 mg/kg per day for 5-10 days depending on the type of infection.
- For most infections, once daily dosing is as effective as twice daily dosing, although once daily dosing has not been evaluated for the treatment of skin infections or pneumonia.
- For most infections in adults the dose of amoxicillin is 250 mg every 8 hours, 500 mg every 8 hours, 500 mg every 12 hours or 875 mg every 12 hours, depending on the type and severity of infection.
- For the treatment of adults with gonorrhea, the dose is 3 g given as one dose.
- For most infections, children older than 3 months but less than 40 kg are treated with 25 or 45 mg/kg/day in divided doses every 12 hours or 20 or 40 mg/kg/day with one-third of the daily dose given every 8 hours depending on the type and severity of the infection.
- Amoxicillin can be taken with or without food.
What Drugs Interact with Cefdinir and Amoxicillin?
- Aluminum or magnesium containing antacids reduce the absorption of cefdinir from the intestine. Separating the administration of cefdinir and such antacids by two hours prevents this interaction.
- Iron supplements also reduce the absorption of cefdinir. Separating the administration of cefdinir and iron supplements by two hours prevents this interaction. There have been reports of reddish stool in patients who have received cefdinir. This could be due to the formation of a chemical complex between cefdinir and iron in the stomach.
Amoxicillin is rarely associated with important drug interactions.
Are Cefdinir and Amoxicillin Safe to Take While Pregnant or Breastfeeding?
- There are no adequate studies of cefdinir in pregnant women; however, studies in animals suggest no important effects on the fetus.
- Cefdinir is not secreted in human milk.
- Penicillins are generally considered safe for use by pregnant women who are not allergic to penicillin.
- Small amounts of amoxicillin may be excreted in breast milk and may cause diarrhea or allergic responses in nursing infants. Amoxicillin is generally considered safe to use while breastfeeding. Amoxicillin is used to treat infections in the newborn.
Latest Infectious Disease News
Daily Health News
Cefdinir and amoxicillin are antibiotics used to treat bacterial infections. Cefdinir is a cephalosporin antibiotic and amoxicillin is a penicillin-type antibiotic.
Multimedia: Slideshows, Images & Quizzes
Ear Infection Symptoms, Causes, and Treatment
Learn about the causes and symptoms of ear infections and how they are diagnosed and treated. Read about treatments such as ear...
What Is a Staph Infection? Causes, Symptoms, Treatments
Do you know what a staph infection is? What about golden staph? Learn about the causes, symptoms, and treatments of staph...
Sinus Infection (Sinusitis) Symptoms & Treatment
Sinus infection (sinusitis) symptoms can include headaches, a sore throat, and toothaches. Antibiotics and home remedies can...
What's Bronchitis? Symptoms and Treatments
Is bronchitis contagious? Learn about bronchitis, an inflammation of the lining of the lungs. Explore bronchitis symptoms,...
Ear Infection Quiz: Test Your Medical IQ
Is it possible to prevent ear infections? Take the Ear Infection (Otitis Media) Quiz to learn the risks, causes, symptoms and...
What happens within the body when a person develops bronchitis? Take this quick quiz to learn the causes, symptoms, treatments,...
Picture of Bronchitis
Acute bronchitis usually comes on quickly and gets better after several weeks. See a picture of Acute Bronchitis and learn more...
Related Disease Conditions
Middle Ear Infection (Otitis Media)
Middle ear infection (otitis media) is inflammation of the middle ear. There are two forms of this type of ear infection, acute and chronic. Acute otitis media is generally short in duration, and chronic otitis media generally lasts several weeks. Babies, toddlers, and children with a middle ear infection may be irritable, pull and tug at their ears, and experience numerous other symptoms and signs. Treatment depends upon the type of ear infection.
Pneumonia is inflammation of the lungs caused by fungi, bacteria, or viruses. Symptoms and signs include cough, fever, shortness of breath, and chills. Antibiotics treat pneumonia, and the choice of the antibiotic depends upon the cause of the infection.
Gonorrhea In Women
Gonorrhea is a bacterial infection transmitted during sexual contact. In women, symptoms include a yellow vaginal discharge, burning or frequent urination, and redness, swelling, burning and itching of the vaginal area. Gonorrhea can be treated with injectable (penicillin) or oral medications.
Bronchitis is inflammation of the airways in the lung. Acute bronchitis is short in duration (10-20 days) in comparison with chronic bronchitis, which lasts for months to years. Causes of acute bronchitis include viruses and bacteria, which means it can be contagious. Acute bronchitis caused by environmental factors such as pollution or cigarette smoke is not contagious. Common symptoms for acute bronchitis include nasal congestion, cough, headache, sore throat, muscle aches, and fatigue. Acute bronchitis in children also my include runny nose, fever, and chest pain. Treatment for acute bronchitis are OTC pain relievers, cough suppressants (although not recommended in children), and rest. Infrequently antibiotics may be prescribed to treat acute bronchitis.
Strep throat is a bacterial infection of the throat. Signs and symptoms of strep throat include headache, nausea, vomiting, sore throat, and fever. Strep throat symptoms in infants and children are different than in adults. Strep throat is contagious and is generally passed from person-to-person. Treatment for strep throat symptoms include home remedies and OTC medication; however, the only cure for strep throat are antibiotics.
Group A Streptococcal Infections
Second Source article from Government
Treatment & Diagnosis
- Ear Infection FAQs
- Bronchitis FAQs
- How Long Does It Take Strep to Go Away?
- How Long Is Pneumonia Contagious?
- Flu Shots - Next Big Influenza Outbreak
- Strep Throat Complications
- Sore Throat: Is It Mono or Strep Throat?
- Acute Bronchitis Treatment Treatment Medications and Home Remedies
- Sore Throat: Virus or Strep?
- Strep Throat Natural Home Remedies
- Acute Bronchitis: How Long Do Symptoms Last?
- Air Travel, Colds, and Sinus Infections
Medications & Supplements
Health Solutions From Our Sponsors
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.