- What is cefadroxil, and how does it work (mechanism of action)?
- What are the uses for cefadroxil?
- What are the side effects of cefadroxil?
- What is the dosage for cefadroxil?
- Which drugs or supplements interact with cefadroxil?
- Is cefadroxil safe to take if I'm pregnant or breastfeeding?
- What else should I know about cefadroxil?
What is cefadroxil, and how does it work (mechanism of action)?
Cefadroxil is an oral antibiotic in the cephalosporin family of drugs, a family that includes cephalexin (Keflex), cefaclor (Ceclor), cefuroxime (Zinacef), cefpodoxime (Vantin), cefixime (Suprax), and many other injectable antibiotics. Cephalosporins stop bacteria from multiplying by preventing bacteria from forming the walls that surround them. The walls are necessary to protect bacteria from their environment and to keep the contents of the bacterial cell together. Bacteria cannot survive without a cell wall. Cephalosporins are most effective when bacteria are actively multiplying and forming cell walls. Cefadroxil is active against many bacteria, including Staphylococcus aureus, Streptococcus pneumoniae, Streptococcus pyogenes, Moraxella catarrhalis, E. coli, Klebsiella, and Proteus mirabilis. The FDA approved cefadroxil in 1977.
Is cefadroxil available as a generic drug?
GENERIC AVAILABLE: Yes
Do I need a prescription for cefadroxil?
What are the uses for cefadroxil?
Cefadroxil is prescribed to treat bacterial infections such as Staphylococcus aureus, Streptococcus pneumoniae, Streptococcus pyogenes, Moraxella catarrhalis, E. coli, Klebsiella, and Proteus mirabilis, urinary tract infections (UTI), throat infections (sore throat), and tonsillitis.
What are the side effects of cefadroxil?
Cefadroxil generally is well-tolerated. The most common side effects are:
- diarrhea or loose stools,
- abdominal pain,
- vomiting, and
Patients who have had allergic reactions to other cephalosporins should not take cefadroxil. Additionally, persons allergic to penicillin or one of its derivatives (for example, amoxicillin [Amoxil, Dispermox, Trimox] or ampicillin [Omnipen, Plycillin, Principen]) may also be allergic to cefadroxil, although cefadroxil has been used safely in such patients.
Other important side effects which are serious, but rare include:
- severe allergic reactions (anaphylaxis),
- and reduced platelet or red blood cell counts.
Cefadroxil can alter the normal bacteria in the colon and encourage overgrowth of some bacteria, specifically, Clostridium difficile which causes inflammation of the colon (pseudomembranous colitis). Patients who develop signs of pseudomembranous colitis after starting cefadroxil (diarrhea, fever, abdominal pain, and possibly shock) should contact their physician immediately.
What is the dosage for cefadroxil?
The recommended adult dose for treating pharyngitis, skin and skin structure infections, and tonsillitis is 1 gram daily as a single dose or in two divided doses.
The dose for urinary tract infections is 2 grams once daily or in two divided doses.
The dose for preventing endocarditis is 2 grams given one hour before a procedure.
The recommended dose for children is 30 mg/kg/day as a single dose or two divided doses.
Which drugs or supplements interact with cefadroxil?
Cefadroxil may reduce the immune response to BCG (tuberculosis vaccine) and typhoid live vaccines and result in less effective vaccination.
Is cefadroxil safe to take if I'm pregnant or breastfeeding?
There are no adequate studies of cefadroxil in pregnant women.
Cefadroxil is secreted in breast milk.
What else should I know about cefadroxil?
What preparations of cefadroxil are available?
Tablets: 1 g. Capsules: 500 mg. Powder for suspension: 125, 250, and 500 mg/teaspoon (5 ml).
How should I keep cefadroxil stored?
Cefadroxil should be stored at room temperature, 15 C - 30 C (59 F - 86 F). Once mixed, the suspension should be refrigerated and discarded after 14 days.
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Cefadroxil (Duricef [Discontinued]) belongs to the drug class cephalosporin. Cefadroxil (Duricef) is prescribed for bacterial infections such as Staphylococcus aureus, Streptococcus pneumoniae, Streptococcus pyogenes, Moraxella catarrhalis, E. coli, Klebsiella, and Proteus mirabilis, urinary tract infections (UTI), throat infections (sore throat), and tonsillitis. Review side effects, drug interactions, warnings and precautions, and efficacy during pregnancy information prior to taking this medication.
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Urinary Tract Infection (UTI)
A urinary tract infection (UTI) is an infection of the bladder, kidneys, ureters, or urethra. E. coli, a type of bacteria that lives in the bowel and near the anus, causes most UTIs. UTI symptoms include pain, abdominal pain, mild fever, urinary urgency, and frequency. Treatment involves a course of antibiotics.
Tonsillitis is a contagious infection with symptoms of bad breath, snoring, congestion, headache, hoarseness, laryngitis, and coughing up blood. Tonsillitis can be caused by acute infection of the tonsils, and several types of bacteria or viruses (for example, strep throat or mononucleosis). There are two types of tonsillitis, acute and chronic. Acute tonsillitis lasts from 1-2 weeks while chronic tonsillitis can last from months to years. Treatment of tonsillitis and adenoids include antibiotics, over-the-counter medications, and home remedies to relieve pain and inflammation, for example, saltwater gargle, slippery elm throat lozenges, sipping warm beverages and eating frozen foods (ice cream, popsicles), serrapeptase, papain, and andrographism Some people with chronic tonsillitis may need surgery (tonsillectomy or adenoidectomy).
Sore throat (throat pain) usually is described as pain or discomfort in the throat area. A sore throat may be caused by bacterial infections, viral infections, toxins, irritants, trauma, or injury to the throat area. Common symptoms of a sore throat include a fever, cough, runny nose, hoarseness, earaches, sneezing, and body aches. Home remedies for a sore throat include warm soothing liquids and throat lozenges. OTC remedies for a sore throat include OTC pain relievers such as ibuprofen or acetaminophen. Antibiotics may be necessary for some cases of sore throat.
Strep throat is a bacterial infection of the throat. Signs and symptoms of strep throat include headache, nausea, vomiting, sore throat, and fever. Strep throat symptoms in infants and children are different than in adults. Strep throat is contagious and is generally passed from person to person. Treatment for strep throat symptoms includes home remedies and OTC medication; however, the only cure for strep throat is antibiotics.
Staph (Staphylococcus) Infection
Staphylococcus or staph is a group of bacteria that can cause a multitude of diseases. Staph infections can cause illness directly by infection or indirectly by the toxins they produce. Symptoms and signs of a staph infection include redness, swelling, pain, and drainage of pus. Minor skin infections are treated with an antibiotic ointment, while more serious infections are treated with intravenous antibiotics.
Pneumonia is inflammation of the lungs caused by fungi, bacteria, or viruses. Symptoms and signs include cough, fever, shortness of breath, and chills. Antibiotics treat pneumonia, and the choice of the antibiotic depends upon the cause of the infection.
Acne is a localized skin inflammation as a result of overactivity of oil glands at the base of hair follicles. This inflammation, depending on its location, can take the form of a superficial pustule (contains pus), a pimple, a deeper cyst, congested pores, whiteheads, or blackheads. Treatments vary depending on the severity of the acne.
Group A streptococcal infections are caused by group A Streptococcus, a bacteria that causes a variety of health problems, including strep throat, impetigo, cellulitis, erysipelas, and scarlet fever. There are more than 10 million group A strep infections each year.
Heart Attack Prevention
Heart disease and heart attacks can be prevented by leading a healthy lifestyle with diet, exercise, and stress management. Symptoms of heart attack in men and women include chest discomfort and pain in the shoulder, neck, jaw, stomach, or back.
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You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.