- Bacterial Infections 101 Pictures Slideshow
- Take the Tummy Trouble Quiz
- Hepatitis C Slideshow Pictures
- What is cefadroxil, and how does it work (mechanism of action)?
- Is cefadroxil available as a generic drug?
- Do I need a prescription for cefadroxil?
- What are the side effects of cefadroxil?
- What is the dosage for cefadroxil?
- Which drugs or supplements interact with cefadroxil?
- Is cefadroxil safe to take if I'm pregnant or breastfeeding?
- What else should I know about cefadroxil?
What is cefadroxil, and how does it work (mechanism of action)?
Cefadroxil is an oral antibiotic in the cephalosporin family of drugs, a family that includes cephalexin (Keflex), cefaclor (Ceclor), cefuroxime (Zinacef), cefpodoxime (Vantin), cefixime (Suprax), and many other injectable antibiotics. Cephalosporins stop bacteria from multiplying by preventing bacteria from forming the walls that surround them. The walls are necessary to protect bacteria from their environment and to keep the contents of the bacterial cell together. Bacteria cannot survive without a cell wall. Cephalosporins are most effective when bacteria are actively multiplying and forming cell walls. Cefadroxil is active against many bacteria, including Staphylococcus aureus, Streptococcus pneumoniae, Streptococcus pyogenes, Moraxella catarrhalis, E. coli, Klebsiella, and Proteus mirabilis. The FDA approved cefadroxil in 1977.
What are the side effects of cefadroxil?
Cefadroxil generally is well-tolerated. The most common side effects are:
Patients who have had allergic reactions to other cephalosporins should not take cefadroxil. Additionally, persons allergic to penicillin or one of its derivatives (for example, amoxicillin [Amoxil, Dispermox, Trimox] or ampicillin [Omnipen, Plycillin, Principen]) may also be allergic to cefadroxil, although cefadroxil has been used safely in such patients.
Other important side effects which are serious, but rare include:
Cefadroxil can alter the normal bacteria in the colon and encourage overgrowth of some bacteria, specifically, Clostridium difficile which causes inflammation of the colon (pseudomembranous colitis). Patients who develop signs of pseudomembranous colitis after starting cefadroxil (diarrhea, fever, abdominal pain, and possibly shock) should contact their physician immediately.
What is the dosage for cefadroxil?
The recommended adult dose for treating pharyngitis, skin and skin structure infections, and tonsillitis is 1 gram daily as a single dose or in two divided doses.
The dose for urinary tract infections is 2 grams once daily or in two divided doses.
The dose for preventing endocarditis is 2 grams given one hour before a procedure.
The recommended dose for children is 30 mg/kg/day as a single dose or two divided doses.
Which drugs or supplements interact with cefadroxil?
Cefadroxil may reduce the immune response to BCG (tuberculosis vaccine) and typhoid live vaccines and result in less effective vaccination.
Is cefadroxil safe to take if I'm pregnant or breastfeeding?
There are no adequate studies of cefadroxil in pregnant women.
Cefadroxil is secreted in breast milk.
What else should I know about cefadroxil?
What preparations of cefadroxil are available?
Tablets: 1 g. Capsules: 500 mg. Powder for suspension: 125, 250, and 500 mg/teaspoon (5 ml).
How should I keep cefadroxil stored?
Cefadroxil should be stored at room temperature, 15 C - 30 C (59 F - 86 F). Once mixed, the suspension should be refrigerated and discarded after 14 days.
Quick GuideSymptoms of Mono: Infectious Mononucleosis Treatment
Cefadroxil (Duricef [Discontinued]) belongs to the drug class Cephalosporin. Cefadroxil (Duricef) is prescribed for bacterial infections such as Staphylococcus aureus, Streptococcus pneumoniae, Streptococcus pyogenes, Moraxella catarrhalis, E. coli, Klebsiella, and Proteus mirabilis, urinary tract infections (UTI), throat infections (sore throat), and tonsils (tonsillitis). Side effects, drug interactions, warnings and precautions, and efficacy during pregnancy information should be reviewed prior to taking this medication.
Multimedia: Slideshows, Images & Quizzes
Strep (Streptococcal) Throat Infection Quiz: Test Your Infectious Disease IQ
Take the Strep (Streptococcal) Throat Infection Quiz to learn about causes, symptoms, treatments, prevention methods, diagnosis,...
Urinary Tract Infection Quiz
How would you know if you had urinary tract infection (UTI)? Take the Urinary Tract Infection in Adult Quiz to learn the causes,...
What Is a Staph Infection? Symptoms, Pictures
Do you know what a staph infection is? Learn about the causes, symptoms, and treatment of staph infections (Staphylococcus...
Related Disease Conditions
Acne is a localized skin inflammation as a result of overactivity of oil glands at the base of hair follicles. This...
Tonsillitis (Adnoiditis, Symptoms, Home Treatment, Pictures, Causes)
Tonsillitis is a contagious infection with symptoms of bad breath, snoring, congestion, headache, hoarseness, laryngitis,...
Pneumonia is inflammation of the lungs caused by fungi, bacteria, or viruses. Symptoms and signs include cough, fever, shortness...
Sore throat (throat pain) usually is described as pain or discomfort in the throat area. A sore throat may be caused...
Strep Throat (Treatment, Causes, Home Remedies)
Strep throat is a bacterial infection of the throat. Signs and symptoms of strep throat include headache, nausea,...
Urinary Tract Infections (UTIs)
A urinary tract infection (UTI) is an infection of the bladder, kidneys, ureters, or urethra. E. coli, a type of bacteria that...
Staph Infection (Staphylococcus Aureus)
Staphylococcus or staph is a group of bacteria that can cause a multitude of diseases. Staph infections can cause illness...
Heart Attack Prevention
Heart disease and heart attacks can be prevented by leading a healthy lifestyle with diet, exercise, and stress management....
Group A streptococcal infections are caused by group A streptococcus, a bacteria that causes a variety of health problems,...
Treatment & Diagnosis
- Urinary Tract Infection FAQs
- Strep Streptococcal Throat Infection FAQs
- Medication Disposal
- Dangers of Mixing Medications
- How To Reduce Your Medication Costs
- Pharmacy Visit, How To Get The Most Out of Your Visit
- Indications for Drugs: Approved vs. Non-approved
- Strep Throat Diagnosis & Treatment
- Drugs: Buying Prescription Drugs Online Safely
- Drugs: The Most Common Medication Errors
- Antibiotics 101
- Generic Drugs, Are They as Good as Brand-Names?
Medications & Supplements
Prevention & Wellness
Infectious Disease Resources
Health Solutions From Our Sponsors
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.