Castleman Disease is a group of related conditions. It is a rare disease with an unknown prevalence. Signs and symptoms of Castleman disease include:
Castleman disease is caused by an abnormal growth of lymphocytes, a type of white blood cell. There are two types of Castleman disease; 1) unicentric, and 2) multicentric. Castleman disease is diagnosed by biopsy of the suspected lymph nodes. Castleman disease is treated with medications (for example, corticosteroids, chemotherapy drugs, immunodilating drugs, interferon-alfa, and anti-viral medications), surgery, and radiation therapy. The life expectancy for a person with Castleman disease is difficult to determine because the condition is rare and takes different forms.Read more: Castleman Disease Article
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Treatment & Diagnosis
Medications & Supplements
- cyclophosphamide (Cytoxan)
- rituximab (Rituxan)
- thalidomide, Thalomid
- Corticosteroids (Systemic, Oral and Injectable)
- etoposide - oral, Vepesid
- vinblastine - injection
- cladribine - injection, Leustatin
- valganciclovir- oral, Valcyte
- carmustine - injection, BiCNU
- etoposide - injection, Toposar, Vepesid
- doxorubicin - injection, Adriamycin, Rubex
- chlorambucil - oral, Leukeran
- vincristine - injection, Oncovin
- lenalidomide (Revlimid)