Casein Peptides

What other names is Casein Peptides known by?

Bovine Casein Hydrosylate, C12, C12 Peptide, C12 Peption, Calcium Caseinate, Casein, Casein Decapeptide, Casein-derived Peptide, Casein Hydrosylate, Casein Peptide, Casein Phosphopeptide, Casein Protein Extract, Casein Protein Hydrosylate, Casein Tripeptide, Casein Tryptic Hydrolysate, Caséinate, Caséinate de Calcium, Caseinates, Caséine de Potassium, Caséine Hydrolysée, Caseins, Concentré de Caséine Hydrolysée, Cysteine Milk Peptide, Extrait de Protéine de Caséine, Extrait de Protéine de Lait, Hydrolysed Casein, Hydrolyzed Casein, Hydrolyzed Casein Concentrate, Hydrolyzed Lactalbumin, Hypotensive Peptides, Isoleucyl-Prolyl-Proline, Lactalbumin Hydrolysate, Lactalbumine Hydrolysée, Lactotripeptide, Micellar Casein, Milk Protein Extract, Milk Protein Hydrosylate, Peptide C12, Peptide Dérivé de la Caséine, Peptides de Caseine, Peptides de Caséine, Peptides Hypotenseurs, Péptidos de la Caseína, Potassium Caseinate, Protéine de Lait Hydrolysée, Sodium Caseinate, Sour Milk Extract, Sour Milk Peptides, Tripeptide de Caséine, Valyl-Prolyl-Proline.

What is Casein Peptides?

Casein is the main protein in milk. It is the ingredient in milk that solidifies when milk curdles. When people drink milk, digestive juices break down the casein into protein pieces called casein peptides. Casein peptides can also be made in the laboratory and marketed as dietary supplements.

Casein peptides are used for high blood pressure, high cholesterol, anxiety, fatigue, epilepsy, intestinal disorders, cancer prevention, and stress reduction.

QUESTION

Next to red peppers, you can get the most vitamin C from ________________. See Answer

Insufficient Evidence to Rate Effectiveness for...

More evidence is needed to rate the effectiveness of casein peptides for these uses.

How does Casein Peptides work?

Some casein peptides are thought to cause blood vessels to enlarge in diameter and therefore lower blood pressure.

Are there safety concerns?

Casein peptides are normally consumed in the diet from milk products. But there isn't enough information to know if casein peptides in dietary supplements are safe.

Special Precautions & Warnings:

Pregnancy and breast-feeding: Not enough is known about the use of casein peptides during pregnancy and breast-feeding. Stay on the safe side and avoid use.

Milk allergy: People with milk allergy are allergic to the proteins contained in milk. They may also be allergic to fragments of milk proteins, such as casein peptides. If you have a milk allergy, it's best to avoid taking casein peptides.

Surgery: Casein peptides might affect blood pressure. There is some concern that casein peptides might interfere with blood pressure control during and after surgery. Stop taking casein peptides at least 2 weeks before a scheduled surgery.

Are there any interactions with medications?


Medications for high blood pressure (Antihypertensive drugs)Interaction Rating: Moderate Be cautious with this combination.Talk with your health provider.

Some casein peptides might decrease blood pressure. Taking casein peptides along with medications for high blood pressure might cause your blood pressure to go too low.

Some medications for high blood pressure include captopril (Capoten), enalapril (Vasotec), losartan (Cozaar), valsartan (Diovan), diltiazem (Cardizem), Amlodipine (Norvasc), hydrochlorothiazide (HydroDiuril), furosemide (Lasix), and many others.

Dosing considerations for Casein Peptides.

The appropriate dose of casein peptides depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for casein peptides. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

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Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, and Insufficient Evidence to Rate (detailed description of each of the ratings).

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Reviewed on 9/17/2019
References

Claustre J, Toumi F, Trompette A, et al. Effects of peptides derived from dietary proteins on mucus secretion in rat jejunum. Am J Physiol Gastrointest Liver Physiol 2002;283:G521-8. View abstract.

Gill HS, Doull F, Rutherfurd KJ, Cross ML. Immunoregulatory peptides in bovine milk. Br J Nutr 2000;84:S111-7. View abstract.

Nishi T, Hara H, Hira T, Tomita F. Dietary protein peptic hydrosylates stimulate cholecystokinin release via direct sensing by rat intestinal mucosal cells. Exp Biol Med (Maywood) 2001;226:1031-6. View abstract.

Park O, Swaisgood HE, Allen JC. Calcium binding of phosphopeptides derived from hydrolysis of alpha s-casein or beta-casein using immobilized trypsin. J Dairy Sci 1998;81:2850-7. View abstract.

Tauzin J, Miclo L, Gaillard JL. Angiotensin-I-converting enzyme inhibitory peptides from tryptic hydrolysate of bovine alphaS2-casein. FEBS Lett 2002;531:369-74. View abstract.

Townsend RR, McFadden CB, Ford V, Cadee JA. A randomized, double-blind, placebo-controlled trial of casein protein hydrolysate (C12 peptide) in human essential hypertension. Am J Hypertens 2004;17(11 Pt 1):1056-8. View abstract.

Wal JM. Cow's milk proteins/allergens. Ann Allergy Asthma Immunol 2002;89:3-10. View abstract.

Wal JM. Structure and function of milk allergens. Allergy 2001;56:35-8. View abstract.

Yamamoto N. Antihypertensive peptides derived from foods. Biopoly 1997;43:129-34.