
Cardiac sarcomas are difficult to treat and often fatal. Even after treatment, chances of recurrence and spread to other organs are high.
Surgery that involves the removal of the entire sarcoma from the heart remains the main treatment option that extends survival. There are reports of people surviving for years after complete surgical removal of the tumor. Radiotherapy and chemotherapy done after surgery have also helped improve outcomes in some people.
However, large-scale studies have reported that the average lifespan of people with cardiac sarcoma is 6 months without surgery. Some studies report that 90% of people with primary cardiac sarcoma treated only with medications survived for only 9-12 months.
According to a study that involved 44 people with primary right-sided cardiac sarcoma, people who received chemotherapy after the surgery lived for 20 months compared with those who did not receive chemotherapy who lived only for 9 months.
Survival rates of cardiac sarcoma:
- 1-year survival rate: 47%
- 3-year survival rate: 16%
- 5-year survival rate: 11%
What are complications of cardiac sarcoma?
Cardiac sarcoma can lead to potentially life-threatening complications:
- Heart attack: When small tumor pieces break and travel through the bloodstream, they can form a blood clot and block the artery that supplies the heart, leading to a heart attack. A heart attack can cause symptoms such as shortness of breath, sudden chest pain, nausea, vomiting, and excessive sweating.
- Stroke: When small tumor pieces break and travel through the bloodstream, they can form a blood clot and block the artery that supplies the brain, leading to a stroke. A stroke can cause weakness or complete paralysis in one or both sides of the body.
- Pulmonary embolism: When small tumor pieces break, they can get lodged in the artery that supplies the lungs and form a blood clot known as an embolus, causing pulmonary embolism. Pulmonary embolism causes sudden shortness of breath, chest pain, and cough (which may be bloody or blood-streaked).
- Pericarditis: Cardiac sarcoma can cause inflammation of the pericardium (the sac that surrounds the heart) and pericarditis. The main feature of pericarditis is a sharp and stabbing pain in the chest, often in the middle (behind the breastbone).

SLIDESHOW
Skin Cancer Symptoms, Types, Images See SlideshowHow cardiac sarcomas are treated
Your doctor will assess various factors before determining the most appropriate course of treatment:
- Age
- Overall health
- Coexisting conditions
- Spread of the tumor
- Tolerance to medications or surgery
- Preference for certain treatment options
Surgery is the most effective treatment option for cardiac sarcoma. While it may not extend the survival of all people with the tumor, it is more helpful than medical therapy alone. Your doctor may recommend one of the following:
- Removing the tumor by open heart surgery: Small cardiac sarcomas can be removed through open heart surgery, in which the surgeon makes a large incision cut in the chest to open the rib cage and operates on the heart.
- Heart transplantation: If the tumor is very large, removal becomes difficult. In such cases, surgeons may recommend heart transplantation. You will have to take immunosuppressants for a long time to avoid your body rejecting the new heart.
- Removing the tumor by autotransplantation: This is a novel type of surgery in which your heart is removed for a period of time to remove the cardiac sarcoma completely, followed by placing your heart back in its original location.
- Chemotherapy and radiation therapy: Your doctor may recommend other cancer therapies such as chemotherapy or radiation therapy if the cardiac sarcoma has spread to other parts of your body. Chemotherapy involves administering drugs that destroy cancer cells, often given in the form of injections or oral pills. Radiation therapy involves the use of targeted high beams of waves that shrink the tumor.
- Clinical trial: You may have the option to participate in clinical trials that try newer medications for cardiac sarcoma. Ask your surgeon or cancer specialist for information.
Can you prevent cardiac sarcoma?
While cardiac sarcomas cannot be prevented, you can avoid risk factors for cancer:
- Smoking or using tobacco
- Excessive alcohol consumption
- Excessive sun exposure
- Excessive radiation exposure
If you have a family history of cardiac sarcoma, you can ask your doctor about genetic cancer screening. Early detection can improve the success of cancer treatment.
Blackmon SH, Reardon MJ. Surgical treatment of primary cardiac sarcomas. Tex Heart Inst J. 2009;36(5):451-452.
Oliveira GH, Al-Kindi SG, Hoimes C, Park SJ. Characteristics and survival of malignant cardiac tumors: A 40-year analysis of >500 patients. Circulation. 2015 Dec 22;132(25):2395-2402.
Cardiac Sarcoma. https://emedicine.medscape.com/article/277297-overview#a1
Top Can You Survive Cardiac Sarcoma Related Articles
Adult Soft Tissue Sarcoma
Soft tissue sarcoma is a rare type of cancer that forms in the soft tissues of the body. Soft tissues include the muscle, tendons, fat, lymph, blood vessels, and nerves. Sarcomas can appear anywhere in the body but are usually encountered in the arms, legs, chest, abdomen, head, and neck. Although the condition primarily affects adults, it can rarely affect children.Cancer
Cancer is a disease caused by an abnormal growth of cells, also called malignancy. It is a group of 100 different diseases, and is not contagious. Cancer can be treated through chemotherapy, a treatment of drugs that destroy cancer cells.Cancer 101 Slideshow
Learn the basics about cancer including types, causes, how it spreads, symptoms and signs, stages and treatment options. Read about the common type of cancers.Cancer Quiz
Take this quiz to learn the causes of cancer. Get the facts about the causes, symptoms, and treatments for the world's most common cancers.Everyday Habits to Lower Breast Cancer Risk
Concerned about your breast cancer risk? Here are everyday health habits you can adopt to improve your odds.Is Tumor a Cancer?
A tumor is a mass or lump of tissue in an organ. In a healthy body, cells grow, divide, and are replaced by new cells. In the case of a tumor, the rate of cell multiplication is more than cell destruction. The word tumor is often associated with cancer; however, not all tumors are cancerous.Less Common Skin Cancers
Merkel cell carcinoma. Merkel cell carcinoma is a rare malignant cancer that usually begins as a single painless lump on the skin. Merkle cells are highly specialized cells in the epidermis that act as pressure receptors. The origin of Merkle cells is debated and proposed to be derived from neural crest cells or other epidermal cells. Merkel- cell polyoma virus infection, ultraviolet radiation and a weakened immune function probably all contribute to the growth of this cancer.Cancer: Symptoms of Common Cancers in Men
Can men get breast cancer? Cancer symptoms men need to watch out for include skin changes, difficulty swallowing, rapid weight loss, a breast mass, and more. Learn possible clues to finding and detecting cancer early.Targeted Therapy: What Is Apoptosis in Cancer Cells?
Cancer cells grow and proliferate endlessly. Targeted therapy to stimulate cell death or apoptosis can help keep tumors in check. Normal cells have a finite cell cycle of growth, division and differentiation. The final stage in the cell cycle is apoptosis, or programmed cell death, when they are infected, old, damaged or simply no longer needed.Targeted Therapy: What Is the Function of A Tumor Suppressor Gene?
Tumor suppressor genes encode proteins to modulate the process of cell growth and replication. Mutations which inactivate the tumor suppressor genes enable cancer cells to grow, unrestrained. Some targeted therapies aim to reactivate these genes, thus suppressing the tumor.What Exactly Is a Tumor?
A tumor is an abnormal growth of cells, which serves no purpose in the body. There are three types of tumors, but it is not always clear how a tumor will develop in the future. Some non-cancerous tumors can become cancerous. Early detection of a lump or tumor is important to determine what will be the treatment.What Is a Grade 4 Tumor?
In grade 4 cancer, tumor cells look very different from the normal cells, and most likely, they have spread to distant organs. Such tumors have a poorer outlook and may need more aggressive management. Usually, tumors in grade 4 are undifferentiated and very aggressive.What Is Cardiac Angiosarcoma?
Cardiac angiosarcoma is an endothelial cell tumor that forms in the inner linings of the organs and typically occurs in the right atrium of the heart.