Can Gout Cause Aplastic Anemia?

  • Medical Author:
    William C. Shiel Jr., MD, FACP, FACR

    Dr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology.

Ask the Experts

My father-in-law has suffered from gout for several years and was put on Col-Benemid (colchicine/probenecid) and developed symptoms of aplastic anemia about 3 years ago. A bone marrow biopsy did not show cancerous cells. After long doses of steroids, his low platlet count, low WBC count, etc. has resolved.

Doctor's Response

Gout can present in association with blood dyscrasias, such as:

It is of note that colchicine (which is a component of Col-Benemid) can cause bone marrow suppression and result in low blood counts.

For more information, please read our full medical article about colchicine uses, side effects and dosage.

REFERENCE:

"Clinical manifestations and diagnosis of gout"
UpToDate.com

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Reviewed on 10/24/2017
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