Calcium D-Glucarate

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What other names is Calcium D-glucarate known by?

Calcio D-Glucarato, Calcium Glucarate, Calcium-D Glucarate, Calcium-D-Glucarate, D-Glucarate (GA), D-glucaro-1,4-lactone (1,4 GL), Glucarate de Calcium.

What is Calcium D-glucarate?

Calcium D-glucarate is a chemical. It is similar to a naturally occurring chemical called glucaric acid. Glucaric acid is found in our bodies as well as in fruits and vegetables such as oranges, apples, brussels sprouts, broccoli, and cabbage. Calcium D-glucarate is made by combining glucaric acid with calcium to make supplements that people use for medicine.

Calcium D-glucarate is used for preventing breast, prostate, and colon cancer; and for removing cancer-causing agents, toxins, and steroid hormones from the body.

Insufficient Evidence to Rate Effectiveness for...

  • Preventing breast, prostate, and colon cancer.
  • Detoxifying the body by removing carcinogens, toxins, and steroid hormones.
  • Other conditions.
More evidence is needed to rate the effectiveness of calcium D-glucarate for these uses.

Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, and Insufficient Evidence to Rate (detailed description of each of the ratings).

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How does Calcium D-glucarate work?

Calcium D-glucarate might lower estrogen levels, and this is thought to be helpful in treating some people with hormone-dependent cancers. There isn't enough evidence to support the use of calcium D-glucarate for preventing cancer in humans.

Are there safety concerns?

There isn't not enough information to know if calcium D-glucarate is safe or what the potential side effects might be.

Special Precautions & Warnings:

Pregnancy and breast-feeding: Not enough is known about the use of calcium D-glucarate during pregnancy and breast-feeding. Stay on the safe side and avoid use.

Are there any interactions with medications?



Alcohol (Ethanol)
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

The body breaks down calcium D-glucarate to get rid of it. Alcohol might increase how fast the body gets rid of calcium D-glucarate. By increasing how fast the body gets rid of calcium D-glucarate, alcohol might decrease the effectiveness of calcium D-glucarate.



Medications changed by the liver (Glucuronidated drugs)
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

The body breaks down some medications to get rid of them. The liver helps break down these medications. Calcium D-glucarate might increase how quickly some medications are broken down by the liver. Taking calcium-D glucarate along with medications changed by the liver might decrease the effectiveness of these medications.

Some of these medications changed by the liver include acetaminophen (Tylenol, others), atorvastatin (Lipitor), diazepam (Valium), digoxin, entacapone (Comtan), estrogen, irinotecan (Camptosar), lamotrigine (Lamictal), lorazepam (Ativan), lovastatin (Mevacor), meprobamate, morphine, oxazepam (Serax), and others.



Kanamycin
Interaction Rating: Minor Be cautious with this combination.
Talk with your health provider.

Kanamycin is an antibiotic. The body breaks down kanamycin to get rid of it. Calcium D-glucarate might increase how quickly the body gets rid of kanamycin. Taking calcium-D-glucarate along with kanamycin might decrease the effectiveness of kanamycin.

Dosing considerations for Calcium D-glucarate.

The appropriate dose of calcium D-glucarate depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for calcium D-glucarate. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.
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Reviewed on 3/29/2011 12:35:40 PM

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