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What is calcitonin? What is calcitonin used for?
Miacalcin nasal spray is a calcitonin, indicated for the treatment of postmenopausal osteoporosis in women greater than 5 years postmenopause when alternative treatments are not suitable. Fracture reduction efficacy has not been demonstrated.
Limitations of Use:
- Due to the possible association between malignancy and calcitonin use, the need for continued therapy should be re-evaluated on a periodic basis
- Miacalcin nasal spray has not been shown to increase bone mineral density in early postmenopausal women
Is calcitonin available as a generic drug?
Do I need a prescription for calcitonin?
What are the side effects of calcitonin?
Side effects from calcitonin are uncommon and usually are mild. Injectable calcitonin can cause:
The nasal spray can cause other side effects including:
The nausea that can occur with injectable calcitonin is unlikely to occur with the nasal spray. In rare instances, the nasal spray can cause an upset stomach.
What is the dosage for calcitonin?
Injectable calcitonin is injected under the skin or into the muscle. The nasal spray is administered into the nostril. To achieve optimal results, patients with osteoporosis should simultaneously receive adequate amounts of calcium and vitamin D.
The recommended regimens for Paget's disease and postmenopausal osteoporosis are 100 units per day injected into muscle or under the skin. Postmenopausal osteoporosis can also be treated with 1 spray (200 units) per day administered in alternate nostrils. Increased blood calcium (hypercalcemia) is treated with 4-8 units/kg of injectable calcitonin every 6-12 hours
Which drugs or supplements interact with calcitonin?
Combining calcitonin salmon and lithium may reduce lithium concentrations due to increased loss of lithium in urine. The dose of lithium may require adjustment.PREGNANCY: There are no adequate studies of calcitonin in pregnant women.
Is calcitonin safe to take if I'm pregnant or breastfeeding?
There are no adequate studies of calcitonin in nursing mothers.
What else should I know about calcitonin?
What preparations of calcitonin are available?
Injection: 200 units/ml. Intranasal spray: 200 units/activation (0.09 ml/puff)
How should I keep calcitonin stored?
Calcitonin should be stored in a refrigerator between 2-8 C (36-46 F). It should be protected from freezing. Bottles of intranasal spray that are being used may be stored at room temperature between 15 C-30 C (59 F-86 F) for 30 days.
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Calcitonin-salmon (Miacalcin) is a man-made version of the hormone calcitonin. Calcitonin-salmon is prescribed to treat osteoporosis (postmenopause), Paget's disease of the bone, and hypercalcemia. Side effects, drug interactions, warnings and precautions, and efficacy during pregnancy information should be reviewed prior to taking this medication.
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Related Disease Conditions
Menopause is the time in a woman's life when menstrual periods permanently stop, also called the "change of life." Menopause symptoms include hot flashes, night sweats, irregular vaginal bleeding, vaginal dryness, painful intercourse, urinary incontinence, weight gain, and emotional symptoms such as mood swings. Treatment of menopausal symptoms varies, and should be discussed with your physician.
Osteopenia is a bone condition characterized by bone loss that is not as severe as in osteoporosis. Bone fracture is the typical symptom of osteopenia, though the condition may be present without symptoms. Treatment involves lifestyle modifications (quitting smoking, not drinking in excess) and ensuring an adequate intake of vitamin D and calcium.
Learn about osteoporosis, a condition characterized by the loss of bone density, which leads to an increased risk of bone fracture. Unless one experiences a fracture, a person may have osteoporosis for decades without knowing it. Treatment for osteoporosis may involve medications that stop bone loss and increase bone strength and bone formation, as well as quitting smoking, regular exercise, cutting back on alcohol intake, and eating a calcium- and vitamin D-rich balanced diet.
Hypercalcemia (Elevated Calcium Levels)
Hypercalcemia is a condition in which calcium levels in the blood are elevated. Hypercalcemia is associated with other conditions such as: hyperparathyroidism, lung cancer, breast cancer, kidney failure, and elevated levels of vitamin D. Symptoms of hypercalcemia include constipation, nausea, abdominal pain, and kidney stones. Treatment depends on the cause of hypercalcemia.
There are four major types of thyroid cancer: papillary, follicular, medullary, and anaplastic thyroid cancer. Tumors on the thyroid are referred to as thyroid nodules. Symptoms of thyroid cancer include swollen lymph nodes, pain in the throat, difficulty swallowing, hoarseness, and a lump near the Adam's apple. Treatment usually involves chemotherapy, surgery, radioactive iodine, hormone treatment or external radiation and depends upon the type of thyroid cancer, the patient's age, the tumor size, and whether the cancer has metastasized.
Paget's disease is a chronic bone disorder due to irregular breakdown and formation of bone tissue. Symptoms of Paget's disease include bone pain, headaches and hearing loss, pressure on nerves, increased head size, hip pain, and damage to cartilage of joints.
Disease Prevention in Women
Disease prevention in women includes screening tests that are a basic part of prevention medicine. All screening tests are commonly available through your general doctor. Some specialized tests may be available elsewhere.
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