calamine and zinc oxide

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jerry R. Balentine, DO, FACEP
    Jerry R. Balentine, DO, FACEP

    Jerry R. Balentine, DO, FACEP

    Dr. Balentine received his undergraduate degree from McDaniel College in Westminster, Maryland. He attended medical school at the Philadelphia College of Osteopathic Medicine graduating in1983. He completed his internship at St. Joseph's Hospital in Philadelphia and his Emergency Medicine residency at Lincoln Medical and Mental Health Center in the Bronx, where he served as chief resident.

What is calamine lotion-topical, and how does it work (mechanism of action)?

calamine is a mixture of zinc oxide and other components. Calamine and zinc oxide are topical anti-itch lotions. Although the exact mechanism of how calamine and zinc oxide work is not known, they have skin protecting and astringent properties that relieve itching. They also seem to slow down bacterial growth, preventing infections from worsening.

What brand names are available for calamine lotion-topical?

Calamine Lotion

Is calamine lotion-topical available as a generic drug?


Do I need a prescription for calamine lotion-topical?


What are the side effects of calamine lotion-topical?

Side effects of calamine and zinc oxide are itching, redness, and irritation.

What is the dosage for calamine lotion-topical?

The recommended dose for calamine and zinc oxide is: Apply to affected areas every 6 to 8 hours as needed.

Which drugs or supplements interact with calamine lotion-topical?

No drug interactions have been established with calamine and zinc oxide lotion.

Is calamine lotion-topical safe to take if I'm pregnant or breastfeeding?

There are no adequate studies done on calamine and zinc oxide to determine safe and effective use in pregnant women.

It is not known whether calamine and zinc oxide enters breast milk.

What else should I know about calamine lotion-topical?

What preparations of calamine lotion-topical are available?

  • Calamine and zinc oxide lotion is available in topical, liquid form.
  • Calamine and zinc oxide is pink-colored suspension, supplied in 4 fluid ounces (118 ml) plastic bottles.

How should I keep calamine lotion-topical stored?

Store calamine and zinc oxide lotion between temperatures 15 C and 30 C (59 F and 86 F).


calamine and zinc oxide (Calamine Lotion) is a mixture of components used to relieve the itching and pain from poison oak, poison ivy, poison sumac, sunburns, and insect and bug bites. Side effects, drug interactions, dosage, and storage should be reviewed prior to using this medication.

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